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Latuda (Lurasidone) Withdrawal Symptoms + How Long Do They Last?

Latuda (Lurasidone) is a new atypical antipsychotic drug that is approved for the treatment of depressive episodes in bipolar disorder (type 1) as well as schizophrenia. It is considered a relatively new drug as it was just approved in 2013 to treat depressive episodes for people with bipolar I disorder. This drug is somewhat unique because it is among very few antipsychotics that are able to treat the depressive side of bipolar disorder.

Although this drug may work well for treating the depression in bipolar I patients, there is not yet substantial evidence proving that it also helps address manic episodes. For this reason, it is sometimes prescribed with lithium as it is known to help control mania. It also has been thought to work well at addressing both the negative symptoms as well as the cognitive symptoms (i.e. memory deficits) among individuals with schizophrenia.

It is thought to help learning and memory as a result of the effect it has on various serotonin receptors. Despite the fact that there is a lot of hype surrounding this new antipsychotic drug, it hasn’t been around long enough for an accurate evaluation; long-term effects are unknown. Most of the studies suggest that Latuda is well-tolerated with minimal side effects compared to other anitpsychotics.

However, just because it is a newer, trendy drug that is touted as having minimal side effects does not mean it is perfect. Many people will still have side effects with this drug and/or find it ineffective at managing their symptoms. A majority of people will try it for awhile, and end up having to face withdrawal symptoms.

Factors that influence Latuda (Lurasidone) withdrawal

As with any antipsychotic drug, there are going to be various factors that play a role in determining withdrawal symptoms. These key factors include: the time span over which you took the drug, your dosage, how quickly you withdrew, as well as other individual factors such as sensitivity to withdrawal.

1. Time Span

How long did you take Latuda? In general, the longer you take an antipsychotic drug, the more difficulty you are likely to have facing withdrawal. When you take an antipsychotic for a long period of time, your body and brain become accustomed to receiving the drug for everyday functioning.

If you take away the substance that you have been supplying your nervous system for an extended period, it is going to have difficulty functioning properly – leading to withdrawal symptoms. Individuals who took Latuda for only a short period of time are likely going to have a much easier time facing withdrawal and readjusting to normal functioning.

2. Dosage (20 mg to 160 mg)

How much Latuda were you taking on a daily basis? Individuals with schizophrenia tend to start at a dose of around 40 mg and then titrate up to a dose that provides symptom relief if the starting dose is inadequate. It can be taken from the starting dose of 40 mg all the way up to a maximum daily amount of 160 mg.

Individuals with bipolar depression typically take anywhere from 20 mg to 120 mg (the daily maximum). It should be noted that titrating upwards from the starting dosage is typically not necessary and doesn’t usually yield any additional benefit. With that said, when a person is taking a higher dose than average, the body can become tolerant to the extra strength of the drug. Withdrawal is thought to be longer-lasting and more severe if you took a higher dose.

3. Cold Turkey vs. Tapering

Despite the fact that many people claim that this drug has minimal discontinuation symptoms doesn’t mean that you should quit cold turkey. It is still relatively new and the jury is still out on how quickly you can come off of this drug. I would recommend conducting a gradual taper just like other antipsychotics.

A tapering protocol that you can use is cutting down by 10 mg every 2 weeks. So if you were on 40 mg, you could drop down to 30 mg after 2 weeks. By dropping at a rate of 10 mg every couple weeks, you are giving your nervous system a chance to gradually adjust to functioning with less of the drug. Tapering is thought to yield significantly less side effects than quitting cold turkey.

4. Individual Factors

It is also important to consider individual factors when coming off an antipsychotic. Some people may not experience many withdrawal symptoms, while others may be plagued with debilitating withdrawal effects for weeks (or months) following their last dose. Certain individuals are naturally more sensitive to withdrawal from drugs than others.

Various factors to consider include: amount of social support, whether you are taking other drugs, whether you are transitioning to another antipsychotic, and your daily habits. People who eat healthy, exercise, and get plenty of sleep may have an easier time recovering from withdrawal symptoms. Additionally people who are taking other drugs or transitioning to another anitpsychotic may not notice nearly as much of a withdrawal.

Latuda Withdrawal Symptoms: List of Possibilities

Below is a list of possible withdrawal symptoms that you may experience when discontinuing Latuda. Understand that you may not experience every symptom listed and that severity of the symptoms can differ based on the individual.

  • Anger: Various individuals have reported that they felt pretty grumpy during withdrawal from Latuda. This is an antipsychotic that tends to have somewhat of an antidepressant effect and works on serotonin. When coming off of it, your neurotransmitter levels may be lower than average, making individuals more prone to anger.
  • Anxiety: Some people experience pretty severe anxiety when they initially quit this drug. Some withdrawal accounts have stated that anxiety was their worst withdrawal symptom and persisted for a long period (in one case months) after the last dose.
  • Body aches: As with most antipsychotics, you may notice that your muscles feel especially achy and/or you may feel weakness as you come off of this drug. Experiencing muscle aches and feeling weak is likely due to your nervous system adjusting to not having the drug for functioning.
  • Concentration problems: Some people notice foggy thinking when they discontinue this medication. The concentration difficulties may be due to the fact that people are experiencing an array of physical side effects while coming off of the drug – which can be distracting. Additionally the cognitive benefits that a person experiences while taking the drug will subside during withdrawal.
  • Confusion: This drug is thought to improve cognition in some people who take it. When you come off of it, the improved cognition will likely subside. The combination of concentration and memory problems during withdrawal can contribute to a general state of confusion.
  • Depersonalization: You may feel unlike your natural self during the withdrawal process. You may feel like a zombie and/or as if your normal self has left your body. This is largely due to changes in neurotransmitters and brain activity as a result of withdrawal. Over time, you should return to feeling like your normal self again.
  • Depression: It is very common to feel depressed during withdrawal from Latuda. In part this may be due to the fact that your brain is no longer receiving the same degree of dopamine and serotonin regulation that the drug provided. When you stop taking it, you may feel even more depressed than before you started taking it. It will likely take some time for your brain functioning to adjust.
  • Dizziness: One of the most common withdrawal effects from any psychiatric medication is that of dizziness. Do not be surprised if you discontinue this drug and notice that you feel extremely dizzy during the first few weeks following your last dose.
  • Fatigue: Some people experience pretty significant fatigue when they stop taking this drug. The fatigue is usually a result of your brain attempting to reestablish normal, sober functioning. The withdrawal can be mentally draining and leave people feeling lethargy.
  • Hallucinations: During withdrawal, it is possible to experience symptoms of psychosis. One of the hallmark symptoms of psychosis is that of hallucinations. Although this it is not common to hallucinate during withdrawal, it is possible as your dopamine activity readjusts.
  • Headache: Perhaps one of the worst symptoms of Latuda withdrawal is that of headaches. Some individuals have reported severe pressure headaches and/or migraines for weeks following their last dose. Do your best to relax, stay hydrated, and consider over-the-counter headache relief if they are substantial.
  • Insomnia: Another withdrawal symptom that people experience is insomnia or the inability to fall asleep at night. This may be severe for the first few weeks of withdrawal, but eventually your sleep cycle should correct itself and this will subside.
  • Memory problems: This drug is thought to help improve cognition and deficits that people experience as a result of schizophrenia. When you come off of it, you may notice that your memory isn’t as good as it was while you took the drug. In some cases your memory may be worse than before you took your first dose of the drug. Unless you had major memory deficits before you took the drug, you should experience full recovery in memory functioning.
  • Mood swings: This is a drug that affects dopamine, serotonin, and adrenergic receptors in the brain. During withdrawal a person may experience abnormal functioning from the receptors affected by the drug – which could be the culprit for mood swings. One minute you may feel hopeful for the future, the next minute completely hopeless and depressed. Just know that mood swings should eventually stabilize (assuming you are non-bipolar).
  • Nausea: Another fairly common symptom that people experience is that of nausea. If this becomes severe enough it may lead to vomiting. This can be reduced by conducting a gradual taper off of the drug. Quitting cold turkey is thought to lead to more significant nausea.
  • Psychosis: Researchers have found that withdrawal from antipsychotics can cause psychosis. In other words, even if you don’t have schizophrenia, but were on an antipsychotic medication like Latuda, you could end up experiencing temporary psychosis. Additionally people who have been diagnosed with schizophrenia may be experiencing a relapse in symptoms.
  • Racing thoughts: Some people have reported experiencing changes in thought patterns upon withdrawal. You may notice that you experience more racing thoughts (not to be confused with mania) and/or unpleasant, intrusive thoughts.
  • Restlessness: You may feel a general sense of restlessness or inability to sit still. Restlessness is often a symptom that occurs when serotonin and dopamine levels are altered. As time passes, you should eventually feel more naturally calm.
  • Sleep changes: Your sleep pattern may become temporarily altered during withdrawal. Many people report that while they are on Latuda they notice a trend of tiredness and others have difficulty getting restful sleep. When you come off of the drug, your natural sleep cycle may require some time to reset itself.
  • Suicidal thinking: Since this medication tends to provide somewhat of an antidepressant effect, coming off of it may lead a person to feel depressed and suicidal. If you feel suicidal, understand that it may be in part due to withdrawal. Seek help from a therapist if you are unable to cope with this feeling.
  • Sweating: You may experience heavy sweats throughout the day and/or wake up with night sweats. Sweating is a common symptom of withdrawal and in part is due to your nervous system adjusting itself and can serve as a natural detoxification response.
  • Tremors: Antipsychotic withdrawal can lead a person to shake uncontrollably or have “tremors.” You may notice that you shake uncontrollably in the hand region and/or throughout the body.
  • Vision changes: You may notice changes in your vision when you come off this drug. The changes are unlikely to be permanent, but you may experience temporary blurs or alterations. These will eventually return to normal with enough time off of the drug.
  • Weight loss: In general, Latuda is considered an antipsychotic that doesn’t tend to lead to drastic weight gain.  Some people experience significant increases in appetite (and craving for carbohydrates) when they are on Latuda. When they stop taking it, their appetite returns to normal and they lose the weight that they gained. Don’t expect immediate weight loss, but just know that you will eventually lose the weight that you packed on.

Latuda Withdrawal Duration: How long does it last?

There is no exact timeline that can be followed when withdrawing from Latuda. The severity of symptoms that you experience as well as the duration for which they persist will be based entirely on individual circumstances. The drug itself has a half life of 18 hours, meaning it will be entirely cleared from your body within an estimated 126 hours (less than 6 days). However, just because the drug is cleared from the body within a couple of days doesn’t mean that withdrawal is immediately over.

Most withdrawal symptoms start after the drug has been fully cleared from the body. Common reported symptoms from antipsychotic withdrawal include: headaches, dizziness, low energy, and changes in mood. Some people may not notice many withdrawal symptoms from Latuda, while others may have difficult, protracted withdrawals that last for weeks, or in more extreme cases, months.

Although withdrawal symptoms may last for an extended period of time, do your best to engage in healthy habits. Getting proper rest, eating healthy, socializing, and getting light exercise can go a long way towards repairing the nervous system.  If you have gone through withdrawal from Latuda, feel free to share your experience in the comments section below, you may really help another person going through the same journey.

Unfortunately this is a relatively brand new drug and there isn’t much literature surrounding its discontinuation and withdrawal symptoms, so any additional insight that can be provided from those who have been on this drug is appreciated.

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192 thoughts on “Latuda (Lurasidone) Withdrawal Symptoms + How Long Do They Last?”

  1. It has been 6 weeks since I have been off of latuda. In August I randomly experienced some electric anxiety on the med and started to experience nausea, loss of appetite and mood swings. I was so freaked out by this I decided to taper. That was late August and it has been absolute hell every since. I went on this med for depression but the withdrawal caused the worst depression I have ever experienced in my life.

    The anxiety attacks I would call terror attacks. I went from daydreaming about suicide as relief sometimes to researching suicide methods with seriousness. I keep getting painful depression periods throughout the day. My life was not like this before. I lost 25 pounds in a month from not eating much and was a binge eater before. I still am having weird dreams. I still have anxiety. My perception is still off. The depression has improved but it’s still terrible which tells you about what this drug caused.

    And to be clear, I went without meds and managed my depression for 4 years so I know my depression. This isn’t just a return of symptoms. The depression was like it wiped everything out my brain. I still sobb on and off throughout the day. But this med is messing with my mind. I don’t want to go on another med but I’m not sure im going to make it.

    Reply
    • Hope you’re doing ok? You described my interaction with latuda… about the suicidal ideation. I used to think of it once in awhile because I saw and went through so much, now it’s really bad. This is the drug, I’m pretty sure.

      Reply
  2. Has anyone experienced an allergic reaction type withdrawal symptom? I was only in Latuda for 3 weeks (20mg, then 40mg then started tapering off back to 20 because I didn’t like the side effects). I have been completely off for four days, and now, I am experiencing itchy, rash like hives on my neck, upper chest and back. I have never had allergies before in my life so I’m not sure if I suddenly developed one to something or if it’s coming off the medicine. So strange!

    Reply
    • This happened to me when I took Ibuprofen. Reading up on it, any pain reliever seems to have a potentially “serious” interaction with Latuda. Once I stopped the pain meds, the itching went away. Hope this helps.

      Reply
  3. I recently stopped Latuda after a long spell of depression. On a side note, it didn’t feel strong enough so I drank nightly to control my symptoms. Long story short, I got really screwed up and my doc took me off it cold turkey. After 2 days I felt like jumping off the balcony and I couldn’t deal with it. I am back on it now, I have eliminated alcohol from my diet and am doing well so far.

    Reply
  4. Bipolar II went from 20mg to 40mg in 40 days. Felt zero improvement in mood. Unbearable side effects: insomnia, restless leg/body, chills/shivers. Felt like I would jump out of my skin. Maddening sleeplessness and body jumpiness. Stopped cold turkey (figured I hadn’t been on it long enough to matter) and am having same side effects a week later. Do not plan on adding another drug to my lithium. This is after 20 years of “try this”, “let’s try this.” etc. Tired of trying.

    Reply
    • I have had a similar experience. I am also Bipolar II and went from 20mg to 40mg in 30 days. I couldn’t bear the side effects (extreme restlessness and insomnia occurred about two hours after taking it; feeling “like I would jump out of my skin” is a good description) so after tapering off to 20mg, I quit cold turkey. I was fine for a few days, but then the side effects started to come back, with the added effects of tremors and a painful headache on the left side of my head about an hour after I get up in the morning each day.

      Reply
  5. I have been taking Latuda for about a year. Depression was worse. Have quit cold turkey for my health and have horrible diarrhea. I am scared. I think I was misdiagnosed and have been for years. I was first diagnosed with severe depression now schizoaffective disorder. I am beginning to think that all psychiatrists are quacks and that a pill is not the answer. Any comments would be helpful.

    Reply
  6. I took Latuda for about 5 weeks. Was up to 60 mgs for less than a week. I don’t know if it helped but I had severe, severe sweating on it. I could hardly dry off from after a shower! I’ve been off it for about 3 weeks and there has been ‘no change’ in the sweating. I can hardly stand it! Does anyone know how long the sweats might last? No other withdrawal symptoms that I know of. I hope there is no permanent damage to my temperature control. Thanks. Lois

    Reply
  7. I have been on latuda 80mg for a year. I started to taper down 2 months ago. Today is day 6 I have been off it and 100mg zoloft. I have been struggling with extreme irritability, panic attacks, disillusion, sleep pattern disrupted, energy level low, mood swings and I think that’s it. So far what I’ve been using to help is xanax .5mg to help me go to sleep. I also exercise at a Crossfit gym 4 to 5 days a week.

    The days I don’t exercise are way worse than the ones I do. I also eat a very strict diet of greens, fresh fruits and veggies and meat and nuts. I keep my meals small so I eat often. Eating healthy has a huge impact on my mood. It feels like my food turns into my mood. If I eat crap most likely that’s how I will feel and vice versa. I’m 6 ft tall and weigh 220lbs… I’m drinking about 1 gallon of water a day. Water also has a huge impact on my mood and my ability to feel balanced.

    It almost feels like the water flushes my system and gives me the ability to feel as good as possible. These exercise and diet habits I have been doing for about a year and a half so that helps a lot too. I did almost cuss my boss out today which I’m sure I would’ve lost my job but instead I prayed first and God told me to keep my big lips shut.

    I listened and I thankfully still have a job. Reading the other comments helps me being into perspective the challenges of doing this med. Sobering but I needed to read it to be prepared for what lies ahead. I also have been masturbating once a day since it does an amazing job at centering me and helping me find a balance. I have a good support network of people, psychiatrist, therapist, wife, 4 yr old son and 1 yr old daughter. My best friend is my God Jehovah who I talk to constantly and who helps me make every decision big and small.

    I hope I’ve helped someone because just writing this has really helped me. I hope all of my mental health brothers and sisters find balance and whatever else it is they are searching for. We are the only ones who truly understand each other and I’m glad this site exist so I could share. I will try to keep checking in thru the stages of my withdrawals.

    Reply
  8. My Dr took me off cold turkey. I have blurry vision, nausea, anxiety, fatigue, body aches, loss of appetite, and restlessness. I don’t think my doctor should have took me off 120mg cold turkey.

    Reply
  9. I took one dose of latuda in the morning and by the end of the night my whole face was swollen. When I woke up the next morning the swelling was so severe I could barely open my eyes let alone keep them open for very long. My lips were tripled in size and I could hardly swallow. My hands was also swollen along with feeling extremely weak and tired. I also had body aches and a headache that kept persisting. I called my pharmacist and she had an urgency in her voice to take benadryl and put an urgent call into my Dr. It’s been three days now and I’m still swollen in my face. So until latuda is completely out of my system I have to take benadryl. I don’t suggest this drug to anyone!!!

    Reply
  10. I been taking Latuda for about 16 days, and after realizing that I was miss diagnosed, and that the effects of the Latuda was more harmful then helpful, I decided to stop taking it. I was on 20mg at nighttime, and I just got past the mark where the drug has left my system (36 hours). I been experiencing what I believe or withdrawals, but not sure.

    I am experiencing nausea, restlessness, and my brain feels tingly or just light headed. I have severe fatigue and soreness all over my body, but especially the legs. My doctor is unavailable (big surprise) and I can not break a 20 into a 10, so decreasing dosage isn’t possible. I imagine the withdrawals will get worse before getting better. My main concern is having seizures from it.

    The only other drug I am taking is Clonazepam at the moment and 10 mg of Lamotrigine, which I am also trying to come off of as well. What should I do? Should I go to the emergency room or just wait it out? Any input would be helpful.

    Reply
  11. I’ve been tapering off of Latuda for 4 weeks from 40mg, to 30mg, to 20mg and on day 11 of the 20’s I started withdrawal symptoms. I am experiencing nausea, trouble sleeping, spaciness, sweating, grumpiness, mood swings, dizziness at times, and memory problems. I don’t understand why all of a sudden I started experiencing this problem. I have a call into the Psych’s office but they haven’t gotten back to me, my Psych is on vacation this week unfortunately. This is miserable. So I have to decide on my own whether to continue at 20, go to 10 or what to do! It sucks.

    Reply
  12. I have been taking 60mg of latuda for about three years. I recently tapered down and eventually got off of it within a month timespan. The withdrawal symptom that I’m feeling the most is nausea. I constantly feel nauseous. Has anyone else gone through this and if so how long did it last after stopping the medication?

    Reply
  13. I also have been taking latuda at 160 mg for a long time and am experiencing weight gain, memory loss, and general “masked face” that is described in medical literature. I want to get off the medication, but I worry from these other posts that I will never be the same again – that I will experience permanent anxiousness, depression, and memory problems even more than I am facing right now – can anyone offer any advice?

    I also feel like maybe I am psyching myself out and that I might be better off with the medication and this is a desire to get off medication altogether, which might not be a productive goal. I would love to speak with anyone about this – I feel alone in that the medical literature is so conflicting with the comments I am reading. I want to return to my normal, bright self before I was diagnosed with schizophrenia!

    Reply
    • I was at 20 mg Latuda nightly for months when I tried getting off. I went to 10 mg for four weeks. This worked pretty well at first. None of the anger, anxiety, muscle pains occurred. I think people should come off of it slower like I did. I was taking it for preventing suicidality. After five and a half weeks off it, I was so suicidal I had to go back on it. I use 10 mg a night and it works great for me at this minimal level. Everyone withdrawing should take it very slow.

      Reply
  14. Long story short, I was put on Latuda last July, had really bad restlessness and anxiety, so they put me on cogentin for side effects. I gained over 50lbs since then. Anyway, it was discovered that my actual diagnosis is actually Complex PTSD as opposed to bipolar, so a few months ago I started getting tapered, gladly, off meds, Latuda being one, down a dosage every two weeks. I was on 100mg Latuda, and the tapering process wasn’t too bad until I got to 40mg. I was there for two weeks, went down to 20mg for almost two weeks, and now I’m off since this past Thursday. It is now Sunday, and I feel SO sick! Mentally I’m OK, but physically I feel horrible! I have severe body/joint and muscle aches, blurred vision, hypersensitivity to sound and light, fatigue, pressure in my head and face, chills, nausea, etc. I hope this doesn’t last too long, I feel miserable!

    Reply
    • I was misdiagnosed too. The antipsychotics only made me flat with little emotion but fear. Just took myself off the latuda due to health problems, plus realize the diagnoses of 1st schizoaffective and later bipolar were wrong. I too have complex PTSD. I have dissociative disorder as well…I zone out. I’ve had a week of amnesia from it 3 times since 2015. Smaller bouts of amnesia last hour plus, I’d like to talk with someone else about it.

      I’m currently seeking a therapist but wont start until I move beginning of January. If you’re interested in sharing more or just talking with someone that probably relates, please email me breebear[AT]outlook.com. The antipsychotics took me from an athletic 130 lbs to 285 lbs diagnosed morbidly obese. Other health problems as a result. I believe that a lot of mental illness could be worked out in long term therapy, with only temporary meds given if at all.

      Exercise and a high veggie/protein/healthy fat diet is working. Past few weeks I have been eating anything due to withdrawal symptoms…so need to get back on track. Very tired, muscle pain and spasm, anxiety, feeling disconnected and like something bad is about to happen. I’m curious if withdrawals could cause a heart attack. Felt like I had one 2 weeks ago…started with pounding heart and palpitations. I didn’t call 911. I’ve been 3 times before and it was anxiety. EMT guy said for me to stop wasting their time.

      Reply
  15. This medication has caused me alot of problems coming out of it, little did I know that all psychotic medication causes diabetes. However, while on it I started having panic attacks and sleepless nights waking up with anxiety. I no longer take the medication and almost 4 weeks after still at night can’t have a full night sleep because I wake up with panic and my heart beats fast. How much longer do I have to wait for everything to get back to normal?

    Reply
  16. I went off 80 mg of latuda cold turkey about a month and a half ago. It gave me severe anxiety and the shakes. I was taking it for 2 years and after I stopped, I realized I hadn’t laughed since I started taking it. Although I am not flat anymore and my real personality is coming back, I have still not been able to laugh. The anxiety is a bit less, but the shakiness and uneasiness is worse. I also feel restless all the time. Does anybody else out there have any of these symptoms and if so, how long does it take before you felt better?

    Reply
    • I was on latuda 60mg for almost three years, and quit it cold turkey. After few days stop taking it, I feeling super super anxious!! Kind of like social phobia or anxiety!! Right now it’s been almost 4 months, and still feeling anxious almost most the time!! And this is the only withdrawal symptom I have! And I really wanna know how long it going to last!?

      Reply
  17. I am coming off of 160mgs of Latuda cold-turkey after 4 months of upping the dosage. I was told it was safe to do so. Further independent research says standard procedure is to wean by 20mgs every two weeks. I’m one week in and I’m having confusion, rage, negative impulses, headaches, and for the past two days very intense pain in any muscle I use in any way, like for typing or nodding my head. No stomach or sleep problems. Very poor memory. Two days ago I didn’t recognize my mom’s face, but I recognized her voice.

    I live with her, so I see her every day. I’m not really experiencing mood swings, and my psychosis has gone way down from when I was on the Latuda. The last increase in dose led to three weeks of a medium-strength mushroom trip, which, to explain, meant that colors changed at random, depth perception changes (for instance, if you’re looking down a hallway, the end of it may stretch away from you a great distance and then rush back toward you), light gets much brighter and then much more dim, and the size and shape of objects changes the longer you look at them.

    The only difference was that there is no increase in dopamine, like on mushrooms, so it’s not “magical”, it is highly disruptive to normal functioning. I’ve done a lot of psychedelics (I don’t anymore), and I have a lot of hallucinations and delusions, so it wasn’t scary unless I was having a paranoid delusion with it, but as it happened I was having them at least twice a day during this time.

    Also, on the Latuda I was having intense chest pain that eventually sent me to the hospital last Tuesday, at which point I was instructed to stop taking it. I also had shooting pains in other, randomized locations on my body on the Latuda. Even though I’m miserable now, I would rather go through intense discomfort now (it should get better once I’m placed on another antipsychotic, my appointment is on Monday) than spend eight weeks detoxing. Plus, it was doctor’s orders.

    Reply
  18. I have been on antidepressants since age 9 (over 20 years), and I am used to withdrawal. The last time they decreased my Latuda was from 120 mg to 40mg in the hospital in preparation for ECTs. Now, I am going from 80mg to 60mg, and am experiencing withdrawal again. One nurse said to go to the hospital, but my GP and pharmacists think I am going through normal withdrawal. I am dizzy, confused, tired, have a head ache, and lack motor skills. I do not have an upset stomach yet, but am prepared. I can’t drive for 2 days.

    Reply
  19. I was on 40 MG of Latuda for 2 months until I increased to 80 MG with the aid of Gabapentin 100 MG 3 times a day and neither of anything for me. I felt exactly the same, if anything worse because I became delusional. I stopped taking it without my doctor’s permission and I have felt no withdrawal symptoms at all.

    Reply
  20. I have been on a number of medications over the last year and a half, with zero affect. The doctors have labeled me as “med resistant” because no matter which medication they put me on, there doesn’t seem to be any affect, aside from side affects that is. I started taking Latuda at 20mg per day, then increased to 40mg. The doctor stated that it should be taken around bedtime, but, some people prefer to take it in the mornings, given the issues I have during the day, I equated having a calmer day to leading into a calmer night… I was wrong.

    About 3 hours after taking this medication it made me feel a way that I really can’t describe… antsy,anxious, rage-filled, severely restless, so I had to switch to taking it at night. I had to time this just right so that I wouldn’t be awake when the effects hit. I stopped taking this medication this past week, I wasn’t experiencing any positive affects from it, and and so no reason to take something that only gave me a negative. I didn’t suffer from any withdrawals, but, I think that would probably attributed to being med resistant.

    Reply
  21. My experience with Latuda has been a living hell. Some of the darkest most terrifying thoughts that have ever been in my head and the closest I’ve ever come to actually killing myself. I don’t know who I am anymore. Will I ever get my life back? I’ve been off it about a week and this is the most depressed I’ve ever been during 20 years of depression. Truly evil side effects.

    Reply
  22. Thank you all for your posts, you have helped me feel a little better while being so sick. I took Latuda for over 4 years and it helped me a lot but I had to take Promethazine with it cause I got severe nausea from the Latuda. I just decided I wanted to be on a cheaper drug and my doctor said I could quit cold turkey since I was on lowest dose. I’ve been physically ill, got horrible headaches and anxiety so bad I ended up in medi-center and given Valium. I would like somebody to post that this stuff will end…eventually. I’m kinda scared I’ll be stuck like this.

    Reply
  23. I was on 20 mg of Latuda for one week, then it was increased to 40mg. I increased it to 40mg on a Friday morning, within two hours I was in the ER with horrible effects. I didn’t take it on Saturday, I appeared to be fine. Sunday morning I took it the same time I did on Friday and was in the hospital again within two hours. The symptoms I was feeling was hot flashes, dizziness, skin flushing, muscle cramping throughout my body beyond belief. I could hardly walk. This medication was stopped by my doctor cold turkey because of the adverse reactions. I feel like total crap, I am on day 2 of not taking this. I hope the withdrawals clear quick!

    Reply
  24. My best friend was on this medication for a month. Then the Dr stopped it upon discharge from the hospital. Within 12 hours of stopping this and starting another like med she lost her balance and fell backwards down a heavily carpeted stairway breaking her neck and dying. Autopsy confirmed she was in multi system shut down from Latuda! Do not ignore changing symptoms. Always get to a Dr or ER and get assistance for your loved ones when any mental or physical changes in Gait or Balance are noted!!

    Reply
    • Psychs need to be held accountable for causing these tragedies with their carelessness. Stories like this are heartbreakingly, infuriatingly common. I’m so sorry for your loss.

      Reply
  25. I’ve been on Latuda for almost 2 years. I had a great experience with it to be honest it helped me through a very hard time in my life with suicidal tendencies. I will say one thing though: despite what it claims about enhancing memory I actually found the opposite to be true. Before I had perfect recall, which was one of my problems because some things shouldn’t be remembered. Once on latuda my memory changed drastically which I never complained about. I’m now going off latuda and have experienced almost zero withdrawal symptoms but its been about 2 weeks and my memory has not yet regained its former state. I’ll give it more time since I was on it awhile.

    Reply
    • Like you, I was put on Latuda for severe depression. It was great! I wasn’t able to tolerate other depression drugs so this was a last resort. After 2 days I felt much better, I also stopped biting my fingers from anxiety. And when I took it with dinner, I had some of the best sleep and dreams of my life. I’ve been on it 3 months.

      And went on vacay and forgot my meds and have gone off cold turkey. The only side effect I’m feeling is a little weepiness and a little nausea, but other than that I’m okay. The depression hasn’t come back so far. So I’m grateful. This drug has been a lifesaver for me but now that I’m doing good without it, I think I’ll stay off it.

      Reply
  26. I’m bipolar 1 and have PTSD. Was on Latuda 60mg for over one month and gained almost 18 pounds. My blood pressure skyrocketed et al. I’m currently being weaned from Latuda and it is a living hell. I’m being tirated from 40mg right now to 20mg next week. For the most part I am having severe depression with significant suicidal thoughts. Anger and rage problems as well as agitation. I cannot get a decent amount of sleep at night and awaken exhausted from nightmares.

    I pray to whomever is up there that this garbage ends soon. ‘Plain old Bipolar mixed with PTSD” is easier to predict and deal with than the withdrawal effects of this crap. I would never recommend Latuda to anyone. Anyone have any idea how long I will be like this? I was only on Latuda for one month. Thanks everyone for sharing, I don’t feel as alone now and I hope that we can all make it through to the other side of this.

    Reply
  27. Was on 60mg for two and half years and quit cold turkey. So far its been about one month from my last dose. I’m feeling very very anxious, and wake up depressed ( 1-2 hrs), and also dizzy.

    Reply
  28. Latuda almost killed me. I began taking it with Trileptal. I was on both for almost 4 weeks. The Latuda attacked my bone marrow (there is correct terminology for this but I like to keep it simple and degenerate) It screwed with specific types of blood cells. I feel like the Trileptal is what made the roof of my mouth swell and hurt so much. Periodontitis erupted in my mouth.

    I couldn’t wake up in the morning. I bled 3 times the normal amount of my usual menstrual cycle within the 4 weeks. I was seeing a clinician who disregarded most of my symptoms blaming them on other things. I’ve done a lot of research on Latuda, everything I experienced is within the information available, even if it is rare/adverse/hypersensitive side effects. What I haven’t been able to determine is if this happened because I already had something cancerous going and simply didn’t know it.

    I had my blood work done yesterday at the ER and it came back fine but I feel like complete crap and am going through different horrible things as each week passes. I have been taking cymbalta for the past 2 weeks because I abruptly discontinued both of the evil meds, hauled off to an urgent care place begging for help with anxiety and depression. I feel awful physically. This is horrible. I have tinnitus, trembling, joint/bone pain, muscle spasms, fatigue and weakness.

    The ER said all of it is because of the Latuda and Trileptal. I could only sleep about 2 hours at a time since abrupt disc before waking up covered in sweat from my chin to my thighs. The cymbalta seemed to put a dent in the night sweats. I can’t wait to feel better again. I will never take bipolar meds again. I pray to God this didn’t set off some kind of cancer in me.

    Reply
  29. Worst feeling I have ever experienced. Taking 80mg I stopped cold turkey. I am feeling: dizzy, nausea, double vision, feeling off my body, no energy, migraine, unable to sleep, very very tired, feel very sad, very very sad.

    Reply
  30. I was on 40 for a few days and stopped the. Did 60 for a few days then stopped then I did 80. For like four or 5 days and got drunk. That did a huge number on my body in where I wasn’t sleeping so took 40 again one night and then 80 the second night. This has caused crazy thoughts and couldn’t feel any pleasure BC my mind was so whacked.

    Started sleeping better but not totally there yet. Still have paranoia and sweating and restlessness. I wasn’t on latuda for long, but mixing it with alcohol after jumping to 80mg in less than a week really screwed with my energy levels in a huge way. Looking forward to returning to normal just don’t know when that will be. God is healing me and my mind WILL be well in jesus name.

    Reply
  31. I have been on Latuda 60mg as a treatment for psychotic symptoms for about 2 years, and I went off cold turkey and have experienced 0 withdrawal symptoms. It’s been about a week.

    Reply
  32. I have only been off my 20mg for 2 days due to insurance issues and I have the worst migraine in my life! The pressure is horrible! And sweating and nausea. But the headache is worse than any. Please if you can taper off this thing do it because this is horrible!

    Reply
  33. On latuda 3 months. Started at 20mg told to stop abruptly at 80mg. Have been experiencing withdrawal symptoms for 2 months now. Suicidal for the first 4 wks. My psych did not see the need for weaning. Bad decision.

    Reply
  34. I started taking 80 mg of Latuda in mid-October 2014 and a month later I started to feel muscle aches, bone aches, joint aches, tingling. I quit cold turkey on January 2, 2015. My doc gave me new medication. Right now its 15 days after I quit cold turkey and the muscle, bone pains are almost gone. I feel better. I did feel confused during my withdrawal. My pains are minor and I hope the pains will go away this week.

    Reply
  35. I was only on for 4 to 6 weeks. Went to the ER with chest pain. Dr said it was the latuda 80 mg. The withdrawal is horrendous: Shakes, chills, high pulse, borderline BP, nausea, diarrhea, no appetite, racing heart, foggy, exhausted, sleepless, dizzy, migraines, muscle pain and fever. I never experienced anything like this. Fortunately my heart is healthy. I hope it stops soon. Called my dr and she’s having me taper over 4 days. I just wonder if that’s enough.

    Reply
    • I took latuda for 5 weeks. I stopped taking it because around week three I started getting agitated really easily. My doc is on vacation and I was taking 20 mg. But I feel really weird right now. My vision feels weird and I’ve had a nervous feeling in my stomach that won’t go away. I can sleep, but that’s mainly because I take sleeping pills. I get random feelings of wanting to throw up. I honestly didn’t think I’d get withdrawals since I’ve only been on it for 5 weeks at a low dose, but I sure don’t feel normal. I feel a deep sense of unease in my own skin. I really hate this.

      Reply
  36. I started taking Latuda at 20mg at bedtime once a day for Bipolar I in August 2013. I was increased all the way up to 80mg at bedtime once a day by December 2014. At first I liked being on it but as the dosages increased I noticed I would get nausea shortly after taking it and headaches. My psychiatrist told me to eat before taking it to reduce the nausea. After being on it for awhile family members told me that I was irritable a lot.

    I have since decided to cold turkey quit the medication because I am fed up with the side effects and my family telling me I am irritable all the time. The side effects I am experiencing during withdrawal this far during cold turkey quitting and I am one week into it have been:

    – suicidal thoughts
    – poor concentration
    – feeling detached
    – poor sex drive
    – depressive mood
    – lack of motivation
    – feeling spaced out

    That’s all I can think of right now. But it is not as easy to get off of as other meds I have been on. This drug is not as great as they make it seem.

    Reply
    • Wow. My boyfriend is going through this right now. We both are extremely angry that his Dr prescribed 80mg for insomnia. My BF is not bipolar and doesn’t have schizophrenia. This is a powerful drug that had actually put out his fire. We finally had a chat about his “checking out” of life and it’s the Latuda. He basically has every single side effect.

      Reply
  37. I have been waking up energized since I started taking Latuda. I am able to sleep at least 6 hours straight then can’t go back to sleep. The suicidal thoughts have stopped as well and I was able go get through Christmas without the extra drama. However, I just ran out and currently have no way of getting more. I’m waiting for my insurance to go through. But long story short, after stopping cold turkey I am still waking up energized but now an hour or two earlier and can’t go back to sleep…

    Reply
  38. I switched to a new psychiatrist last week, and he completely changed my meds around. I was taking 15mg Prozac, 900mg lithium, and 80mg Latuda. Well, this new doc took me off of Latuda cold turkey, is tapering my lithium down each week, and increased my Prozac to 40mg. This started on 12/11 and on 12/15 I started having really bad withdrawals and I cannot figure out why or what it is from, but I’m assuming it’s the discontinuation of the Latuda. I’ve been having tremors, mood swings, anger, irritability, blurry vision, and I feel like I’m out of my mind….like I’m sitting here but my brain is on the other side of the room floating. I’ve sent a message to my Dr. to see what I am supposed to do because all of these withdrawals are horrible!

    Reply
    • Find a different doctor. None of these meds should be stopped cold turkey. If you are bipolar, an antidepressant will swing you over to mania and possible psychosis.

      Reply
  39. I’ve been on Latuda for over 2 years. My Dr put me all the way up to 160mg. I started experiencing muscling stiffness and and horrible muscle spasms. As time went on I began experiencing more side effects such as exhaustion, deeper depression however no manic spells at all. Which with a 3 and 4 year old I could’ve kinda used the energy. My hair began falling out in clumps, lock jaw, chewing and sucking on my tongue and worst of all I started to lactate.

    Yes from my breast, how embarrassing during an intimate moment. This medicine wasn’t helping me I felt worse about myself gained over 75 pounds. I didn’t know what to do. Now I’m dosing down. It feels horrible. Restlessness, severe increased anxiety, body aches, head aches double vision, fainting. I’m just praying that this will all dissipate and I’ll start to have clarity again. Hope this helps anyone.

    Reply
    • I feel for you. I hope you are doing better now. They put my son on 160mg and ruined our life. It was so hard to come off this drug. Everyday was a crisis for 2 years on this drug and coming off of it. 160 mg would only be prescribed by a quack!

      Reply
      • I took Latuda 80mg down to 40mg, then down to 10mg. Decreased dosage because I felt extremely foggy and lethargic. Sometimes it felt like my brain was on fire. I’m guessing it was too much serotonin levels for me to handle. Turns out I switched MD’s and he took me off it. Just taking Lamictal 150mg every day.

        I tapered by taking one 20mg tab and cutting it into 4 pieces and then 8. Taking crumb sized pieces. When I got down to my last pill I took one piece every other day, till gone. I have increased levels of energy and I don’t get mood swings anymore at all. I felt like the med was making me have random bursts of uncontrollable anger. I feel great now, just dealing with migraines that won’t quit.

        It’s been 2 weeks since I’ve been off and I’ve had a migraine almost every day. So bad I was thinking of going back on it. I’m assuming this won’t last long. Also I’ve been having periods of confusion, not sure it’s associated with the migraine considering it’s a symptom of migraines, I’m hoping these migraines will stop harassing me. Leaving work early and missing days due to a migraine is really getting me down.

        I’m completely fine for the most part but do have some anxiety/insomnia (Doctor have me on trazodone and klonopin). Getting off such an intense/strong drug is so hard. Glad to hear that some people are having the same symptoms. Hang in there I say… thanks for sharing your stories.

        Reply
  40. I was on 2 mg of Latuda for one week and then my doctor upped it to 40 then eventually 60 mg a day over the course of 3 weeks. When my dose increased, I felt extreme panic, extremely restless movements, feeling as if the walls were closing in around me. I felt hopeless and paced around my home for 4 hours praying for the dreadful symptoms to subside. I even contemplated calling 911. Luckily my boyfriend was able to come home from work and console me until I passed out from literal exhaustion.

    My doctor told me to immediately stop taking it and prescribed me Xanax to handle any withdrawal symptoms if I were to have any. I did have severe headaches, insomnia, lack of normal appetite. About one week later, I had my follow up appointment and my Dr. prescribed me Depakote. My bipolar manic and depressive symptoms are all but gone and I feel hopeful that I am on the right track. So don’t give up hope, there will always be the medicine for you.

    Reply
  41. I have insurance through my husband overseas so I have to pay in advance (get reimbursed 3 months later) and was horrified to discover the price is $854 at CVS for a 30-day supply (dosage 40 mg). I pay 20% of medicaments so I am just shocked at the price. The drug is too new for them to experiment on me and for me to get locked in at that price. If something should happen to my insurance and to be on a drug that costs that much… I may be insane but I’m not crazy. I was given 4 one-week packs so hopefully quitting cold turkey will not be too bad. I experienced a lot of dizziness and brain zaps getting off Prozac and Neurontin 13 years ago when I was last on medication. Good luck to all.

    Reply
    • First I thought there were substantial discount coupons available for most people. Don’t ask me how or what, I am in Canada. One months supply is $145. I get 120 mg dosage and split it 4 ways. Doesn’t matter what the dose is the price is the same. Pretty screwy but once you figure it if your doc will cooperate it gets fairly reasonable.

      Reply
    • I had been on it for almost a year. I had met my deductable last year, and now that it’s the new year I found that my 30 day supply was around $900. I couldn’t afford it, so I quit cold a few weeks ago. Today has been the 1st really low day I have had, feel out of my body and just not myself. I have been crying for no reason and just lethargic all day. Not sure if this is withdraw or my mind’s “normal” state.

      Reply
  42. I for one am having serious withdrawal symptoms. Mood swings, lack of energy, suicidal thoughts. I even wrote down my possible suicide note for my loved ones and friends to cope with. Every day is a struggle and I find myself wondering if today is the day that I will date my goodbye note. I already called my therapist, hopefully the pharmacy will have something for me tomorrow. Recommendation, withdraw slowly not cold turkey.

    Reply
    • My psychiatrist switched me from Latuda to Geodon while I was in the hospital about a week and a half ago. I really wish he would stop taking me off medications cold turkey because I’ve always had to deal with substantial withdrawal symptoms. Anyway, since he took me off Latuda I’ve been extremely dizzy, I’ve been depressed, anxious, suicidal, and my thoughts have been increasingly difficult to understand. It’s hard to function because I have a heck of a time following conversations, putting an intelligent thought together, and I’m so easily distracted – I hope that’s the withdrawal, anyway, otherwise I’m in trouble.

      Reply
  43. I had a very rapid w/d from latuda and at first I had flu like symptoms, sweating, nausea, insomnia and an internal fear inside and severe depression. It’s been 9 weeks off and I have windows of feeling ok than the internal fear comes back and I’m paralyzed. It also gave me severe anxiety that I never had before. Could it be protracted withdrawal. It should of been a 3 month taper and was done in 8 days.

    Reply
    • I’m 6 weeks off now, was on 60mg for almost 3 years. Since I stopped, I’m feeling super super anxious too, it’s kind of like social anxiety, which I never had before. I want to know are you feeling the same, or anyone?

      Reply
      • I went off rapidly as well and yes super social anxiety. I don’t leave the house, see no friends and barely answer the phone. Horrible!

        Reply
      • I’ve been on it for three years at 120mg, I dropped to 60mg about three months ago and same thing. Lots and lots of anxiety. Kind of like a prolonged mild panic attack.

        Reply
      • I was on 120 mg of Latuda as well as 400mg of Lamictal. I’ve tapered off both and it’s been about a week and a half. I feel terrible. I had to call in sick to work today. I gained about 80 lbs and am happy to see the weight go down but this is the only good thing. Has anyone tried cannabis to help with the anxiety?

        Reply
    • I have been on this medication for over a year and have found my anxiety has steadily increased over time. It’s to the point now where I’m agoraphobic and cannot go anywhere or do anything without being anxious. I have found out it may be due to this med. I am currently weaning down my dose to find out if this is truly the cause. Coming off of 40 mg down to 20, then off completely… you are not the only one who has been anxious on it!

      Reply
      • This is exactly how I am feeling!! I can barely do anything and when I do I’m a nervous wreck the whole time. I’ve been on it for years and getting off of it. Was on 40 mg now tapering off to 20 mg for a week then done. I’m so nervous about the withdrawal symptoms!! I hope it makes my horrible anxiety go away!!

        Reply
  44. “The worst side effect I experienced and still am is the act that my tongue is pressed up against the roof of my mouth continuously”

    I have that exact side effect if I take it in the day. People who haven’t experienced it wouldn’t believe how annoying and distracting it is.

    @Nicole: did that happen if you took it before bed? As I said, I’d never intentionally take it during the day, but the restlessness was never a problem if I took it less than an hour before bed. Of course, that means you need to eat a large snack right before bed, which I really don’t need.

    I’m just off it for a few days because of a prescription mixup, and the lightheadedness from withdrawal is pretty bad. Feels like a combination of a hangover and the flu. Hope I don’t go through the initial screwed up sleep phase again when I start up next week.

    Reply
    • Look up tardive dyskinesia… Tell your doctor if your experiencing any symptoms involving tongue neck or any involuntary muscl 3 problems. THEY CAN BE PERMANENT. Latuda works for me, however, when I forget two days in a row, it’s the worst withdrawals you could ever imagine. Worse than opiates or benzos. The thought of something happening and running out scares me so much I’m weening off rather than reaping the benefits.

      Reply
      • You are the first person on here to describe what the withdrawal feeling is for latuda after 2 days. If I forget to take after a couple of days I start to feel like a zombie and my sleep pattern gets all screwed up. I have been on it for about 6 months. It is amazing how after remembering to go back on a regular schedule again how quickly it works. I guess it is a lot stronger drug than I thought. I take it along with Celexa. I had a spinal cord injury 12 years ago and because of the nerve damage if I don’t take celexa everyday I end up all I want to do is cry. Thanks for your comment it has helped me.

        Reply
      • I have tried twice to get off this stuff. I currently take 40 mg. While on it I do great and feel great, but I hate meds. So I tried tapering. I take it at night-by 10 am the next morning I am ready to jump off a bridge and so restless I can’t stand it. My old shrink just said to stop cold turkey but she was a flake.

        I worry about the long term effects of this, but I’ve never felt this good my whole life, so I guess I will take meds for the rest of my life. I’m not going to try to stop it anymore. I can tell my brain is altered, but it beats the alternative. Otherwise, I love this stuff. My insurance doesn’t cover it, so Im worried about the day the samples will no longer be available.

        Reply
        • You can buy it in Canada for much cheaper. My husband bought the 80mg and cut it in half. So, we were getting a two months supply for $175. Much better than US prices.

          Reply
  45. I had a HORRIBLE experience with Latuda, which is weird because my psychiatrist said most people really do well on Latuda. It gave me a feeling of EXTREME restlessness that I could not bear. I couldn’t even drive on it because it made me so restless I just wanted to drive off the rode or crash my car. I was on 20-40 mg for two weeks and I just could not stand this feeling. It also gave me pretty bad nausea… Withdrawing from it now and still experiencing the nausea and some restlessness. It was like a devil drug for me and it scared me away from all antipsychotics. The side effects are so hard to deal with and it sucks because I really need to take them.

    Reply
    • I’ve been taking Latuda for about 3 weeks now. It’s in addition to Wellbutrin 450mg and Pristiq 50mg… added to help with suicidal ideation etc… I’ve had success with Abilify and Seroquel, but didn’t like the weight gain… The Dr started me slowly, cutting the pill in half for 2 days then another 2 days on next dose, etc… “Because she could,” she said.

      No problems except the slight nausea… But definitely taking it with food helps!!! When I got up to 40mg, I believe, I experienced the symptom you’re describing… Maybe the second day on that dose. It’s called akathisia, which is common with antipsychotics (I guess?) and the Dr had warned me about this. She added Cogentin .5 mg (tablet cut in half) to take with the Latuda…

      Saying that I could go w/ the the full 1mg, if needed. After about 2 weeks, the .5mg Cogentin was causing slightly-blurry near vision and mild light sensitivity… So I stopped it one night and (surprisingly) I found I no longer needed it, my body had adjusted to the Latuda. Just thought I’d share that you can get over this initial “tense/crawling” sensation if you stick with it. I’m now taking 80mg without Cogentin…

      And I’ll see how this works for me. My thoughts do seem clearer, but it’s definitely making my mood kind of indifferent, so I’m interested how this is going to go. FYI, I was looking up withdrawal symptoms because this drug is a huge pain in the ass to get and I thought I’d have to go a few days without it until my Rx arrived after the 3-day weekend.

      Luckily I was able to get *4* tablets from a pharmacy an hour away… LOL! ? For serious. This stuff is expensive! I hope it works!!

      Reply
    • I also had EXTREME restlessness. My legs, my body. Which really sucked because I considered this drug my miracle drug. I got rid of my suicidal thoughts my depression that came alone with my bipolar. But sadly I had to quit. I did this and right now I have extremely dry mouth, vertigo, nausea, vomiting, still restless but mainly my legs now and not as bad.

      I’ve also had weakness after stopping. I’m really disappointed that I had to quit because of the insomnia and extreme restlessness. I really liked myself on this drug. :-(

      Reply
      • @ Molly… What was your dosage for Latuda?… I am on 40 mg and considering tapering off… I’m currently on another medication for the insomnia :/

        Reply
  46. I’ve been taking Latuda around 5-6 weeks and found it helpful in eliminating suicidal thoughts. All of a sudden (yesterday and today) I am seeing double and I am not able to walk a straight line. I am all over the place. What happened? I am unable to drive due to my double vision. I am waiting to talk to my doctor, but know I must discontinue this drug. Apparently it often is a bad combination with Lithium. Bummer.

    Reply
    • Debbie, I’ve been on Latuda for about 8 weeks and just like you, I’ve experienced some relief from the horrible and persistent suicidal thoughts. I had bad blurred vision from the beginning but I was hoping it will go away. My Dr. lowered the doses to 20, but the blurred vision didn’t go away. Today she told me to stop it an she prescribed Lithium instead. I will taper off although she said to just stop it! I hope it goes well for you.

      Reply
  47. I was taking latuda for 2 years and experienced severe side effects such as impaired judgment, confusion, nausea, tremors, pulling my tongue back just to name a few. I’ve been off of latuda for about a month now and feel my mind begin to clear up. The withdrawal I’ve experienced from it has been sweating, sleeplessness. I don’t want to go back to this drug nor any other antipsychotic medicine I’d prefer to hear voices instead.

    Reply
    • I have the same experience with my tongue, I was off this medicine more than a week ago and I still can’t properly chew food. I hope it will go away and is not permanent. Do you think it can stay permanent or I should wait?

      Reply
        • There is a medication called cogentin that helps with those side effects. Ask your Dr about it. I’ve taken it the whole time I’ve been on Latuda. I started it when I was taking geodon because I was having a severe stiff neck. It’s called an extrapyramidal effect.

          Reply
  48. This is bad sh#t. I’ve been on it for five days and have been sick every day. Severe severe headaches, nauseau, GI problems, anxiety, anger just to name a few. The side effects are not going away as I was told. I am getting off.

    Reply
  49. I have been off of Latuda for over 3 weeks now. While I was on it I experinced extreme insomnia to the point where I only got 1-2 hours of sleep a night. I also experienced a lot of sweating. The worst side effect I experienced and still am is the act that my tongue is pressed up against the roof of my mouth continuously. Be careful with this drug!

    Reply
  50. I have been on latuda for 3 months on 40 mg. I went down to 35 and two days later experienced horrible depression. I would say 10 mg is too much to titrate off try 5 if you can even tolerate that. Its a serious drug. Helpful but hard to decrease.

    Reply

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