A 2026 analysis linked emotional disorders in heart failure to poorer cardiovascular health, oral-health burden, and oral microbiome dysbiosis, but the strongest mediation signal came from oral health rather than systemic immune-inflammation index.1 In fully adjusted NHANES models, emotional disorders were associated with lower Life’s Essential 8 cardiovascular health, OR 0.39, while self-rated oral health …
A 36-person experiment found that 18 Hz infrasound raised salivary cortisol and negative mood appraisal even though participants did not detect the infrasound above chance (p = 0.241).1 The result is a controlled acute signal, not proof that every real-world low-frequency noise complaint is physiologically caused by infrasound. Research Highlights Cortisol rose with infrasound: Infrasound …
A 40-rat early-life visceral stress study found auditory pathway sensitization without hearing-threshold loss: neonatal colorectal distension produced IBS-like visceral hypersensitivity, normal ABR thresholds, shortened auditory brainstem latencies, increased amplitudes, and 219 differentially expressed cochlear proteins.1 The result turns IBS-like stress exposure into a gut-pain and sensory-processing question. Research Highlights Visceral hypersensitivity was strong: At 20 …
A 2026 Generation Scotland study linked traumatic physical injury to diagnosis-stratified blood methylation differences in 4,308 people.1 The clearest recurrent-depression signal pointed toward oxytocin signaling and synaptic-plasticity pathways, but the result is still exploratory pathway evidence rather than a blood test for depression or PTSD. Research Highlights Recurrent depression carried the strongest phenotype signal: traumatic …
A 2026 systematic review argues that catatonia should be read as a limbic-cortical circuit syndrome, with motor shutdown tied to brain systems for threat, salience, motivation, and emotional regulation. Research Highlights 20 studies met criteria: the 2026 review screened 1,792 records, assessed 54 full texts, and included 20 articles: 13 observational studies and 7 case …
A 2026 iScience study found that both humans and rats could report whether their own 2-second timing responses were small-error or large-error trials, but rats were more accurate on test choices: human accuracy was 55%-57%, rat accuracy was 65%-67%, and the species gap remained significant before task-variable matching.1 Research Highlights Both species monitored timing errors: …
A 2026 humanized P301S tauopathy mouse study found that syntaxin-6 knockout partly rescued early motor impairment from months 1 to 4, protected gait at 5.5 months, reduced frailty (p = 0.0052), and reduced superficial-cortex neurodegeneration at 3 months (p = 0.0055).1 The finding strengthens syntaxin-6 as a tauopathy modifier, but it is still mouse genetics, …