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Adult ADHD Trials Often Skip Full Diagnostic Assessment

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A 2025 scoping review of 292 adult ADHD randomized controlled trials found that 49.7% allocated diagnosis without a general psychopathology assessment, and only 35% reported that psychiatrists or psychologists assigned the ADHD diagnosis. Research Highlights 292 adult ADHD RCTs were reviewed: Studart et al. screened 706 PubMed records and included 292 randomized controlled studies.1 49.7% …

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Antidepressants Did Not Shift Facial Emotion Recognition in Depression

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A 2026 ANTLER mechanistic analysis found no evidence that maintaining antidepressants preserved a happier facial-emotion recognition pattern compared with placebo substitution at 12 weeks (adjusted mean difference 0.23, 95% CI −0.5 to 1.0, p = 0.5) or 52 weeks (0.29, 95% CI −0.5 to 1.2, p = 0.5). Research Highlights No 12-week maintenance advantage: discontinuation …

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tDCS for Empathy: rTPJ Increased Other-Pain Signals, DLPFC Did Not

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A 2026 Psychological Medicine study involving 196 healthy adults found that transcranial direct current stimulation over the right temporoparietal junction increased cognitive empathy signals across pain and video tasks, while left dorsolateral prefrontal cortex stimulation produced narrower and less consistent effects.1 The useful finding is anatomical calibration: rTPJ looked more like an other-state representation target, …

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Saudi Medical Students Had 30% Health Anxiety in 650-Person Study

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A 2026 multi-university survey involving 650 Saudi medical students found that 30% met a threshold for clinically significant health anxiety, with higher adjusted odds among female students, rural students, private-university students, and students with psychiatric history.1 The result is not a diagnosis of “hypochondria”; it is a screening signal that illness-focused fear may be a …

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Healthcare Moral Injury Study Links NHS War-Mode Leadership to Stress

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A 2026 qualitative study of 71 UK National Health Service workers argued that a shift into “war-mode” leadership during an atypical crisis could push moral stress, distress, conflict, and suffering toward moral injury.1 Moral-injury endpoint: moral injury was the severe endpoint, while unresolved lower-consequence moral phenomena may become the pathway to it. Research Highlights 71 …

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Severe Infections Predicted Dementia After 27 Comorbidities in Finland

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A nationwide Finnish registry study found that 2 severe infection categories still predicted dementia after adjustment for 27 noninfectious comorbid diseases.1 Cystitis and bacterial infection of an unspecified site both had adjusted rate ratios of 1.19 after comorbidity adjustment, meaning the infection-dementia association did not disappear when prior hospital-treated illnesses were modeled. Research Highlights The …

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Amitriptyline Water Pollution Impaired Male Guppy Spatial Accuracy

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A 2026 Environmental Science & Technology experiment found that wild guppies still reduced maze solve times with practice after 11-day exposure to environmentally motivated amitriptyline concentrations, but exposed males made 26.35% to 34.21% more navigation errors than control males.1 The result is a sex-specific accuracy signal, not a blanket claim that antidepressant pollution erased learning. …

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