A 2026 randomized trial in early postmenopausal women found that 8 weeks of app-based combined aerobic and resistance exercise reduced Beck Depression Inventory scores by 7.30 points, compared with 2.20 points after education-only control and 5.65 points after face-to-face exercise. A structured home program delivered through a mobile platform improved depression, fatigue, sleep quality, and …
A 2026 polysomnography study involving 685 children found that neck-to-height ratio identified moderate/severe pediatric obstructive sleep apnea better than BMI Z-score, waist-to-height ratio, or hip-to-height ratio. The signal was useful but not diagnostic: neck-to-height ratio reached AUC 0.781 overall, which is strong enough for triage but not strong enough to replace a sleep study.1 Research …
A 2026 multi-ancestry genome-wide association study of urinary aMT6s, a melatonin metabolite used as a proxy for overnight melatonin secretion, found 0 genome-wide significant loci in 11,744 people, even though 23 variants reached suggestive significance and 8 were supported by 2 analytic methods. Research Highlights No common variant dominated: the 2026 GWAS meta-analysis involving 11,744 …
A 2026 mixed-methods study of 32 chronic non-cancer pain patients found the strongest satisfaction signal when prescribed cannabis-based medicines affected stress, sleep, coping, anxiety, appetite, and daily function — not pain intensity alone.1 Research Highlights 32 patients were interviewed: Pombeiro Stein et al. studied adults from a German pain clinic who had used physician-prescribed cannabis-based …
A 2026 population-based polysomnography study involving 1,206 adults found current smokers had 1.75x higher odds of worse obstructive sleep apnea severity than non-smokers or occasional smokers after adjustment for age and body mass index. Former smokers showed almost the same overall signal — 1.76x higher odds than never smokers — but that part of the …
A 2026 randomized sham-controlled trial in 76 adults with primary insomnia found an 8-week Sancai acupuncture protocol reduced post-treatment Insomnia Severity Index scores to 7.80 vs. 16.45 with sham acupuncture, while total sleep time increased to 366.83 minutes vs. 287.97 minutes.1 Research Highlights Insomnia severity fell far more with real acupuncture: Zhao et al. randomized …
A 2026 randomized trial in 63 adults with type 2 diabetes found that progressive muscle relaxation was linked to a large fatigue drop in the intervention group, from a Fatigue Severity Scale mean of 51.58 to 34.12, but adjusted between-group tests did not confirm a clear advantage over control for fatigue or sleep quality.1 The …