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Sleep Disorders vs. Systemic Immune-Inflammation Index (SII) in the U.S. Population (2023 Study)

Sleep and inflammation have long been topics of scientific inquiry, with a growing body of evidence underscoring their intricate relationship. The systemic immune-inflammation index (SII), a novel marker based on leukocyte parameters, has emerged as a significant indicator of systemic inflammation. A recent study explored the association between sleep-related disorders and SII, revealing intriguing connections …

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Valerian Root for Insomnia & Sleep: Is It Actually Effective? (2023 Review)

Valerian, a herb long cherished for its sedative properties, stands at the crossroads of traditional medicine and modern scientific inquiry. Despite its widespread use across cultures for promoting sleep and alleviating insomnia, the scientific community remains divided over its efficacy. Highlights: Historical Significance: Valerian has been used since the times of ancient Greece and Rome …

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tDCS for Insomnia & Sleep Disturbances: Targeting the Infralimbic Cortex to Ventrolateral Preoptic Area Pathway (2024 Study)

In the quest to effectively treat insomnia, a condition plaguing millions worldwide, scientists are exploring innovative treatments beyond traditional medication. Transcranial Direct Current Stimulation (tDCS) emerges as a promising intervention, offering a non-invasive method to modulate brain activity and enhance sleep quality. A recent study suggests tDCS may treat stress-related sleep disturbances and highlights the …

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Reset Modafinil Tolerance with Drug Holidays & Pitolisant-Bridging? (2023 Study)

Narcolepsy, a chronic neurological disorder, significantly impacts the daily lives of those affected due to excessive daytime sleepiness (EDS). Modafinil has been a cornerstone in managing EDS, but its effectiveness can wane over time due to tolerance. An innovative approach, using the drug pitolisant during modafinil ‘drug holidays’, offers new hope for resetting tolerance and …

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Anabolic Androgenic Steroids vs. Sleep Quality & Psychological Distress in Weightlifters (2024 Study)

Recent research has analyzed the relationship between the use of Anabolic Androgenic Steroids (AAS), sleep quality, and psychological distress. A new study specifically evaluated the effects of anabolic steroids on sleep patterns during both active use and withdrawal phases, among male weightlifters in Norway. Highlights: A large proportion of men using AAS report experiencing sleep …

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Medical Cannabis for Generalized Anxiety Disorders & Sleep Disturbances (2023 Study)

Recent research has shed light on the potential benefits of cannabis-based medicinal products (CBMPs) in treating Generalized Anxiety Disorder (GAD), especially in patients with sleep disturbances. Recent research explored the effectiveness of CBMPs on GAD, the role of sleep quality in treatment outcomes, and the incidence of adverse events. Highlights: CBMPs Show Promise in Treating …

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ZzzQuil Side Effects & Adverse Reactions (List)

ZzzQuil is an over-the-counter medication utilized most frequently to enhance sleep quality among individuals with allergies or the “common cold.”  However, because ZzzQuil is a potent sleep aid, individuals without health problems sometimes use the medication to help manage insomnia.  On occasion, ZzzQuil is even administered for the treatment of motion sickness and extrapyramidal symptoms …

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