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Alzheimer’s Fingerprick Blood Biomarkers: p-tau217 and GFAP Track Cognition

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A 2026 PROTECT study involving 174 older adults found that self-administered fingerprick p-tau217 correlated with episodic memory (r = 0.299, p < 0.001) and GFAP correlated with working memory (r = 0.183, p = 0.034), supporting remote Alzheimer's risk triage rather than a stand-alone dementia diagnosis. Research Highlights Fingerprick sampling reached 77% completion: 174 of …

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Amitriptyline Water Pollution Impaired Male Guppy Spatial Accuracy

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A 2026 Environmental Science & Technology experiment found that wild guppies still reduced maze solve times with practice after 11-day exposure to environmentally motivated amitriptyline concentrations, but exposed males made 26.35% to 34.21% more navigation errors than control males.1 The result is a sex-specific accuracy signal, not a blanket claim that antidepressant pollution erased learning. …

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Lobar Brain Bleeds Carried 3.49x Dementia Risk in NLP Stroke-Subtype Study

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A 2026 Scottish health-system preprint used natural language processing of CT and MRI reports to subtype stroke and found that lobar intracerebral hemorrhage carried a higher dementia risk beyond 6 months, aHR 3.49 vs matched controls.1 The method reduced unspecified stroke coding from 26.1% to 3.4%, making location-specific prognosis easier to see. Research Highlights Lobar …

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CoQ10 Preserved Working Memory in Drp1-Deficient Mice Through Coa6

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A 2026 mouse study found that long-term CoQ10 exposure reduced working-memory errors in Purkinje-cell-specific Drp1-deficient mice, tying the behavioral rescue to Coa6 binding and support for mitochondrial respiratory-chain function.1 The result supports a narrow mechanistic CoQ10-Coa6 pathway under neuronal mitochondrial dysfunction while leaving human memory-supplement claims untested. Research Highlights Working memory improved in a mouse …

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Blood microRNAs Linked to Hippocampal Atrophy in Rhineland Study

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A 2026 Molecular Psychiatry analysis from the Rhineland Study found that blood-derived microRNA signatures were associated with hippocampal brain structure: 6 microRNAs linked cross-sectionally to left hippocampal volume, and 5 different microRNAs linked longitudinally to hippocampal atrophy rates.1 The result is biomarker-discovery evidence for brain aging, not a ready dementia blood test. Research Highlights Baseline …

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Mild COVID Cognition Improved After Alpha/Delta and Omicron

A 2026 longitudinal study found reassuring cognitive trajectories after mild-to-moderate COVID-19: Alpha/Delta and Omicron groups both improved by follow-up, and neither group showed persistent neuropsychological test deficits vs. population norms. Psychiatric symptoms and fatigue were also broadly similar across variants.1 Research Highlights 55 adults were assessed: 27 were infected during the Alpha/Delta era and 28 …

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