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Lurasidone Improves Positive Symptoms of Schizophrenia More Than Negative

MHD featured image for Lurasidone PANSS Domains: Positive Symptoms Lead, Negative Lag.

Lurasidone is approved for schizophrenia and bipolar depression on the strength of acute trials that mostly reported a single number: the change in PANSS total score. A 2026 post-hoc analysis of the JEWEL Phase 3 trial pulls that number apart, looking separately at five symptom domains and at all 30 individual items of the PANSS …

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Psychedelic Media Coverage Outpaced Evidence (2017–2024)

Photoreal illustration of newspaper headlines and scientific journals about psychedelic treatments, conveying media-evidence calibration.

Psychedelic-assisted therapy has been one of the most-covered mental-health stories of the past decade. A 2026 quantitative analysis by Evers and colleagues maps how media enthusiasm grew, peaked, and partially pulled back across major U.S. outlets — and how the coverage related to the actual evidence base for depression and PTSD.1 Research Highlights Psychedelic clinical …

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Teenage Cannabis Use vs. Cognition and Brain Development: THC vs. CBD (Toxicology Data)

Photoreal illustration of an adolescent brain with overlay of cannabis molecules and cognitive metrics, conveying developmental neurocognitive impact.

Studies of adolescent cannabis effects on cognition have been limited by self-report and confounding. A 2026 longitudinal study by Wade and colleagues uses the Adolescent Brain Cognitive Development (ABCD) cohort with both self-report and biological toxicology, separating THC and CBD effects on developing cognition.1 Research Highlights Adolescence is a critical window for cognitive maturation, with …

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Naltrexone/Bupropion Reduced Food Intake in Binge-Eating Lab Study

Photoreal illustration of brain reward circuitry overlaid on imagery of palatable food, conveying pharmacological reduction of consummatory reward.

Lisdexamfetamine remains the only FDA-approved medication for binge-eating disorder — a serious condition affecting roughly 1.2% of adults. A 2026 human laboratory study by McKee and colleagues tests whether naltrexone/bupropion, already approved for obesity, reduces the food-reward mechanisms that drive binge episodes.1 Research Highlights Binge-eating disorder (BED) is the most common eating disorder in the …

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Uncensored Media Trauma and Modern Psychological Effects

Photoreal illustration of a person scrolling through phone with overlay of trauma imagery, conveying mental health impact of uncensored media.

The internet era has dramatically changed how people are exposed to traumatic events — uncensored video of violence, war, and disaster reaches civilian audiences within minutes of occurrence. A 2026 study by Allouche-Kam and colleagues examines the mental health consequences of this indirect-trauma exposure in modern populations.1 Research Highlights Indirect trauma exposure through media has …

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