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Web-Based Exercise Reduced Postmenopause Depression and Sleep Scores

MHD featured image for web-based exercise, postmenopause depression symptoms, fatigue, and sleep quality.

A 2026 randomized trial in early postmenopausal women found that 8 weeks of app-based combined aerobic and resistance exercise reduced Beck Depression Inventory scores by 7.30 points, compared with 2.20 points after education-only control and 5.65 points after face-to-face exercise. A structured home program delivered through a mobile platform improved depression, fatigue, sleep quality, and …

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iSupport-Malaysia Dementia Caregiver Program Scored 74.3 on Usability

A 2026 mixed-methods preprint found that iSupport-Malaysia, a multimedia web-based dementia caregiver psychoeducation program, reached a good System Usability Scale score of 74.3. That is enough to justify pilot testing, but not enough to claim caregiver mental-health benefit: 33.3% of usability-test participants failed sign-up, 20.0% failed search, and Loh et al. did not measure burden, …

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LIFU vs. rTMS for Stroke Recovery: Same 2-Week Endpoint, Larger FMA Gains

MHD featured image for LIFU vs. rTMS in post-stroke motor recovery.

A 2026 secondary randomized-trial analysis found that low-intensity focused ultrasound and repetitive transcranial magnetic stimulation reached statistically similar 2-week post-treatment motor scores after subacute stroke, even though LIFU produced larger median Fugl–Meyer Assessment gains than rTMS: 7 vs. 2 upper-limb points and 3 vs. 1 lower-limb points.1 LIFU therefore carries the recovery-dynamics signal in this …

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Levetiracetam Range in Children: 2.82-24.37 mcg/mL TDM

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A 2026 real-world study involving 1,174 children with epilepsy proposed a levetiracetam therapeutic drug monitoring range of 2.82-24.37 mcg/mL, much lower than commonly cited adult-style ranges, but the same data also warned against treating a drug level as a stand-alone seizure-control predictor. Research Highlights Lower pediatric range: Sun et al. proposed an observational levetiracetam range …

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Autoimmune Focal Epilepsy: Antibody Testing and Immunotherapy

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A 2026 structured review of autoimmune drug-resistant focal epilepsy argues for a narrow but clinically important claim: immune mechanisms can make seizures refractory in selected patients, but the evidence supports targeted testing and immunotherapy triage rather than treating every medication-resistant seizure disorder as autoimmune. Research Highlights Autoimmune epilepsy is a subset: Kunecki et al. estimated …

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Prostate Cancer Survivors Who Smoke Showed Lower Verbal Memory Scores

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A 2026 study involving 118 prostate cancer survivors found the clearest lifestyle-cognition signal around smoking: smokers learned fewer words across repeated verbal-memory trials, while obesity and physical activity produced narrower reaction-time findings and no significant anxiety or depression differences. Research Highlights Smoking tracked verbal learning: in 118 prostate cancer survivors, smokers scored lower on Verbal …

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Multiple Sclerosis Iron MRI Linked to Cognitive Impairment in 12 Studies

MHD featured image for multiple sclerosis, iron-sensitive MRI, and cognitive impairment.

A 2026 systematic review of advanced neuroimaging in multiple sclerosis narrowed 600 database records to 12 studies and found the clearest cognition signal in basal ganglia iron-sensitive MRI measures, while thalamic susceptibility was more variable and often tangled with atrophy. Research Highlights Basal ganglia signal was strongest: across 12 studies, elevated susceptibility or iron-related metrics …

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