Thin Child to Heavier Adult Linked to Depression and Anxiety
In 447,821 UK Biobank adults, those who recalled being thinner than average at age 10 and had a high adult BMI had the highest rates of later depression and anxiety.
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Celecoxib Reduced Depression-Like Behavior and Brain Inflammation in Stressed Rats
In a 2026 study of 40 male rats under 6 weeks of daily restraint stress, 2 weeks of celecoxib improved open-field, maze and swim-test behavior and lowered hippocampal TNF-alpha, IL-1beta, IL…
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Higher Body Fat Linked to Lower Alzheimer's Risk in Older Adults
In 2,349 dementia-free older adults in China, the highest quarter of estimated body fat had about half the rate of Alzheimer's-type MCI over about 2 years. The link is observational and not …
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Higher Blood Pressure After Stroke Linked to Cognitive Decline and Dementia
In 5,128 stroke and TIA survivors from the PROGRESS trial, higher average and cumulative blood pressure over 18 months was linked to cognitive decline or dementia; each 15 mm Hg higher avera…
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Sleep and Activity Tracking Helped Tell Bipolar From Unipolar Depression
In 159 depressed adults at a Paris hospital, a model built from sleep questionnaires, wrist actigraphy and a sleep-lab night distinguished bipolar from unipolar depression (AUC 0.926 in 36 p…
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Lingering Depression Symptoms in Bipolar Disorder Linked to Poorer Functioning
In 133 bipolar I outpatients between episodes, those with mild lingering depression symptoms had poorer functioning and more self-stigma, impulsivity, and anxiety.
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6 Medicine Groups Linked to Fatal Overdoses in Bipolar Disorder
In a Finnish registry study, recent prescriptions for 6 medicine groups were linked to higher odds of fatal poisoning in bipolar disorder. Lithium was not.
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