Research Highlights One published case is not a base rate. Roelandt and colleagues (2026) describe a 25-year-old multimorbid patient who developed severe ketamine addiction after a single 75 mg intranasal sub-anesthetic dose given for acute suicidality. It is N = 1, but it is now the second published case after Bonnet 2015 of post-clinical-use ketamine …
Loneliness raises measured risk of Alzheimer’s, suicidal ideation, and completed suicide. The associations are documented; the precise magnitudes are not.
Modern administrative cohorts find no dementia signal for ECT and link it to lower suicide and mortality. The supportive literature carries known biases worth flagging.
Major Depressive Disorder (MDD) is not just a mental health concern; it’s a complex interplay of psychological, environmental, and biological factors, where the most tragic outcome can be suicide. Recent research has unveiled a potential link between the immune system’s inflammatory response and the increased risk of suicide among those suffering from MDD. By examining …
Suicide, a tragic end to around 800,000 lives each year, remains one of the most perplexing and devastating phenomena in mental health. Despite the vast number of studies and data, accurately predicting who is at risk of suicide has remained largely elusive, with current tools heavily reliant on subjective assessments and the clinician’s experience. A …
Circadian rhythms, the natural cycles of physiological and behavioral processes occurring within a 24-hour period, play a crucial role in our overall well-being. Recent research highlights the significant impact of these rhythms on the severity of major depressive disorder (MDD) and, crucially, on the intensity of suicidal ideation among those affected. A new study analyzed …
Suicide remains a leading cause of death worldwide, with its prevention a top priority for both public health initiatives and individual care strategies. Recent research in the US Army offers new insights into the genetic underpinnings of suicide attempts, suggesting that polygenic risk scores (PRS) could become a valuable tool in identifying individuals at risk. …