Whole-body hyperthermia looks less like generic relaxation and more like a timed biological stressor: in a small depression substudy, a single session was followed by early Hamilton Depression Rating Scale improvement, heat-shock gene activation, and immune-process enrichment that included interleukin 6 production. Research Highlights Depression scores improved early: in the 18-person RNA sequencing substudy, whole-body …
A 299-person remote randomized trial found that 10 min of daily focused-attention meditation reduced anxiety and mind wandering more than waitlist control, with the strongest gains among adults who started with higher internalizing symptoms. Research Highlights Anxiety improved in the randomized phase: Glick et al. randomized 299 meditation-naive adults and found greater 8-week Generalized Anxiety …
A 2026 Phase I crossover trial found that a 400-mg powdered cannabidiol formulation reached peak CBD faster than Epidyolex oil in healthy adults — 3 h vs. 3.5 h when fasted and 5 h vs. 8 h after a high-fat meal — but food still dominated the exposure story.1 Research Highlights Faster peak: CBtru powder …
A 2026 nationwide Korean analysis found that resistance exercise was associated with lower depression and anxiety scores after propensity score matching, while aerobic exercise alone was not significantly associated with either outcome. The result favors adding weights, bands, machines, or body-weight strength work to mental-health exercise advice without assuming that lifting caused the lower symptom …
CBD has solid evidence for rare pediatric epilepsies, preliminary signal in anxiety and psychosis, and insufficient evidence for most conditions it’s marketed for.
‘Depression is inflammation’ holds for a subgroup of patients, not for everyone. Community-sample and twin data weaken the broader version of the claim.
CBT-I beats sleep medications long-term and self-help versions work too. Sleep hygiene alone isn’t enough — the two are routinely conflated.