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Psychological Burnout & Increased Risk of Cardiovascular Disease (CVD) (2024 Review)

Burnout, once a fringe topic relegated to the backburners of occupational health discussions, has emerged as a critical public health crisis with far-reaching consequences. Beyond its immediate toll on mental health and workplace productivity, burnout’s insidious effects extend to one of the body’s most vital systems: the cardiovascular system. Highlights: Elevated Risk: Individuals experiencing burnout …

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Effects of Stress & Negative Life Events on Brain Structure Connectivity in Adolescents (2024 Study)

Adolescence marks a pivotal era of transformation, where the brain undergoes significant development, shaping the trajectory of an individual’s emotional and psychological maturity. Recent studies, including one leveraging data from the IMAGEN Consortium, have evaluated how negative life events during these formative years can subtly yet significantly alter the structural connectivity of the adolescent brain. …

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Saffron Extract (Affron) Reduces Stress via HPA Axis & Neuroplasticity in Rats (2023 Study)

In a world increasingly burdened by the psychological strains of modern living, the quest for effective and safe treatments for stress-related symptoms has never been more urgent. A recent study evaluated the stress-mitigating properties of Affron® – a Saffron extract – in animal models, revealing its potent effects on the body’s stress response systems, including …

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tDCS for Insomnia & Sleep Disturbances: Targeting the Infralimbic Cortex to Ventrolateral Preoptic Area Pathway (2024 Study)

In the quest to effectively treat insomnia, a condition plaguing millions worldwide, scientists are exploring innovative treatments beyond traditional medication. Transcranial Direct Current Stimulation (tDCS) emerges as a promising intervention, offering a non-invasive method to modulate brain activity and enhance sleep quality. A recent study suggests tDCS may treat stress-related sleep disturbances and highlights the …

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Chronic Stress Alters the Gut Microbiome & Intestinal Barrier in Mice with Sex-Specific Effects (2023 Study)

The gut-brain axis, a complex communication network linking the gastrointestinal tract and the brain, plays a pivotal role in maintaining both mental and physical health. Recent studies illuminate how chronic stress disrupts this intricate system, particularly affecting the intestinal barrier in the jejunum, and contributes to the pathogenesis of Major Depressive Disorder (MDD). This emerging …

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Psychiatric Disorders Linked to Accelerated Aging in UK Biobank Study (2023)

Recent research utilizing data from the UK Biobank has shed light on the intricate relationship between biological aging and mental health, particularly focusing on depression and anxiety in older adults. A large-scale study linked advanced biological aging with increased risks of developing mental health issues, suggesting that biological aging could be a significant factor in …

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Effects of Social Isolation on the Brain & Behavior in Fruit Fly Models (2023 Study)

Social isolation is a phenomenon that transcends species, affecting individuals from diverse biological backgrounds in profound ways. It is not just a human experience but a universal condition with deep-rooted impacts on mental health and behavior. Highlights: Social Isolation Across Species: From humans to fruit flies, social isolation has universal, profound impacts on mental health …

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