Mental Health DailyResearch. Evidence. Perspective.Published research on Headaches.
The MIND migraine feasibility study showed that remote migraine-cognition monitoring can produce a large daily dataset: 177 baseline participants completed 3,688 smartphone assessments, cove…
Read articleA 2026 iScience metabolomics study found 211 differentially expressed metabolites in migraine patients with patent foramen ovale; in a 220-person validation cohort, lower indoleacrylic acid …
Read articleA 2026 study by Bai et al. in Dialogues in Clinical Neuroscience uses Mendelian randomization (MR) — inherited genetic variants as a natural experiment to test causality — and concludes that…
Read articleA 2026 review argued that G protein-coupled receptor 30 may connect estrogen signaling, trigeminal pain pathways, and migraine biology, but migraine-specific human trials of GPR30-targeted d…
Read articleA 2026 cross-sectional study of 79 adults receiving hemodialysis found dialysis headache in 40 patients (50.6%), and a prior history of recurrent headaches was the strongest adjusted signal:…
Read articleMigraine, a primary headache disorder, significantly impacts the quality of life of millions worldwide. In recent years, the focus has shifted toward developing targeted therapies, particula…
Read articleMonosodium glutamate (MSG), commonly used as a flavor enhancer, has been controversially linked to headaches for decades. Key Facts: Human studies linking MSG to headaches have inconsistent …
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