A 2026 emergency department claims analysis estimated 3.87 million United States ED visits in 2021 where take-home naloxone could have been clinically relevant, compared with 226,453 ED-treated opioid-overdose visits in the same database.1 The finding reframes naloxone distribution as an emergency-care workflow for overdose risk, polysubstance exposure, long-term opioid use, and patients who arrive after …
A 2026 ABCD Study preprint found that teen substance-use initiation prediction improved more when models included changing risk over time than when they simply switched from logistic regression to multi-task learning.1 Dynamic models raised AUROC by 0.044 to 0.062 in multi-task learning and by 0.050 to 0.084 in logistic regression, which makes timing the main …
A Saudi dental-clinic study found very high caries burden, but dental fear and anxiety were not the main adjusted explanation for dental caries. In 619 Al Ahsa patients, 89.5% had caries, 36.3% reported dental fear, and 25.8% reported anxiety; age, education, and oral hygiene carried a stronger caries signal than fear or anxiety.1 Research Highlights …
Australian coronial data show that fatal poisonings involving new psychoactive stimulants and hallucinogens were rarely single-drug events. In 70 toxicology-confirmed deaths from 2007 through 2025, 92.9% involved other psychoactive drugs and 75.7% involved multiple stimulants or hallucinogens. Research Highlights Fatal cases were usually polysubstance cases: 65 of 70 deaths (92.9%) had psychoactive drugs beyond the …
Warm AI chatbots can feel more supportive while becoming less reliable. In a 2026 Nature experiment across 5 language models, warmth fine-tuning raised wrong-answer rates by 7.43 percentage points on average, and the gap was largest when users sounded sad.1 Research Highlights Warmth came with an accuracy cost. Models trained to sound warmer made more …
The “men have shallower friendships” story is too blunt. In a 2026 Sex Roles analysis of 1,899 young adults, the familiar gender friendship gap was largely driven by one group: white men reported the lowest closeness to best friends, while Black men, Latino men, and women across ethnoracial groups looked much more similar after adjustment.1 …
A 2025 preregistered meta-analysis found that temporary social media abstinence did not significantly improve positive affect, negative affect, or life satisfaction across 10 adult experiments involving 4,674 participants.1 The result does not prove that every break is useless, but it challenges the generic “digital detox” claim that simply logging off reliably improves mood. Research Highlights …