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Seroquel (Quetiapine) Withdrawal Symptoms: How Long Do They Last?

Seroquel (Quetiapine) is a short-acting atypical anitpsychotic drug that is primarily used to treat schizophrenia and bipolar disorder. In some cases it is also used as an antidepressant augmentation strategy to treat major depression. It is sometimes used to help manage Alzheimer’s disease and is used at low doses for the treatment of insomnia. Despite the fact that this medication has a variety of uses, it should really only be used for its intended purpose – to treat schizophrenia and possibly bipolar disorder.

Many people take it and it works great to help people manage the positive symptoms of schizophrenia. It also helps prevent major mood swings among individuals with bipolar disorder. With that said, not everyone responds well to this drug – in some cases the side effects become unbearable. Additionally, for some individuals this drug doesn’t work well enough to justify continued usage.

Although this is a drug that can be beneficial for some people, the long term effects are not very promising. In many cases, this drug actually worsens intellectual functioning – especially in elderly with dementia. It also tends to elicit a variety of unpleasant side effects for the person taking it including: weight gain, sexual dysfunction, drowsiness, and worsened motor functioning.

Factors that influence Seroquel withdrawal include…

When you withdraw from any medication, there are important factors that will influence your withdrawal. These factors include: time span, dosage, your physiology, and whether you tapered off of the drug or quit cold turkey.

1. Time Span

How long were you taking Seroquel? If you were taking it for an extended period of time (e.g. over a year), you are likely going to have a tougher time coming off of the drug than someone who only took it for a few months. If you were on this drug for many years, it may be extremely difficult to quit.

2. Dosage (150 mg to 800 mg)

What dosage were you taking? In general, it is hypothesized that the higher the dosage you take, the more it alters your brain functioning. If you take a high dose for a long term, it is going to take your brain a much longer time to normalize in regards to neurotransmitter functioning. The drug comes in doses ranging from 25 mg, 50 mg, 100 mg, 200 mg, 300 mg, and 400 mg.

For treatment of schizophrenia, most people take between 150 mg and 800 mg per day. If you are on the 800 mg dose, it may take longer for you to withdraw. Fortunately the dosing is nice if you need to conduct a gradual taper – you can keep cutting your dose in half.

3. Individual Physiology

A lot of withdrawal symptoms will be influence by your individual physiology. Despite the fact that many people experience the same symptoms when they quit taking this drug, some people don’t experience as many symptoms, while others experience more symptoms. Another thing to consider is whether you have a mental illness like schizophrenia or bipolar. Withdrawal can trigger symptoms or a relapse of symptoms related to the illness for which you were taking it.

4. Cold Turkey vs. Tapering

How should you quit taking Seroquel? For most people, it is highly recommended to conduct a gradual taper. If you are on a higher dose and you quit cold turkey, you will likely be unable to function. By conducting a gradual taper (e.g. slowly reducing the dosage over time), you are allowing your body and brain to slowly adjust to changes.

If you have been on the drug for a long period of time, even tapering may be difficult. If you are someone that quit cold turkey and aren’t looking back, prepare yourself for a long recovery period and symptoms that feel as if they are never going to go away. If you haven’t yet quit this medication and want to taper, slowly reduce your dosage every few weeks. It may take months to taper off of your medication, but it will minimize the withdrawal symptoms.

Seroquel Withdrawal Symptoms: List of Possibilities

Below are a list of common symptoms that have been reported during Seroquel withdrawal. Keep these symptoms in mind when you come off of the medication so that you know what to expect. Although you may not experience every symptom on the list, it is likely that you will experience something when you quit taking this drug.

  • Agitation: If you feel especially agitated, it’s because you’re brain is no longer receiving the drug. This drug helps many people stay calm and reduces agitation. When a person quits taking it, they may become increasingly agitated and it may last for awhile.
  • Anxiety: In many cases this drug helps people with anxiety. When you stop taking it, your anxiety may skyrocket. Everything you do may provoke nervousness and intense anxiety. Try to realize that it is just from withdrawal and that you will recover.
  • Concentration problems: Although this drug can cause concentration problems while you take it, you may also experience poor concentration when you stop it. Some people call this “brain fog” or foggy thinking – it is due to the fact that your brain is trying to readjust itself.
  • Depression: When withdrawing from this antipsychotic you may spiral into deep depression. Any medication that affects neurotransmitters can result in depression when you withdraw – especially if it had a subtle antidepressant effect when you took it.
  • Dizziness: A common withdrawal symptom from any psychiatric medication is dizziness. This may be extreme when you quit taking Seroquel, but shouldn’t last longer than a few months. For most people, this sensation goes away after a few weeks, but for some, the dizziness persists for a long time. Don’t freak out if the dizziness lasts longer than you anticipated – realize that it is a result of post-acute withdrawal.
  • Fatigue: Feeling excessively lethargic, tired, and fatigued is common when quitting an antipsychotic. Although this medication tends to be sedating while you take it, the withdrawal takes a toll on overall energy levels. When your brain is trying to readjust, you may become extremely tired and feel like sleeping all day.
  • Headaches: It is common to experience headaches when you quit taking Seroquel. The headaches may be minor or may feel like full blown migraines. These will subside eventually, but may last weeks before they go away.
  • Heart rate changes: You may notice that your heart rate becomes excessive when you quit this drug. Some people notice that their heart beats excessively fast when they withdraw. You may also notice heart palpitations – these are caused by both withdrawal and anxiety.
  • Hypersensitivity: A person may become hypersensitive to sights and sounds when they come off of this medication. The person may not realize that it is from drug withdrawal and their neurotransmitters are not functioning properly. Therefore normal sounds may sound excessively loud and normal sights may appear excessively bright.
  • Insomnia: It is common to experience insomnia when you quit this drug. Insomnia is usually caused by anxiety and/or sleep disruptions. Your entire sleep cycle may be thrown off when you quit this drug and you may experience increased anxiety.
  • Irritability: Don’t be surprised if you become increasingly irritable and difficult when you stop this drug. In general the medication tends to calm people down almost to the point of a stupor. If you feel excessively irritable, know that it’s likely a result of withdrawal.
  • Itching: Some people notice when they quit this drug that they become itchy all over. If you are experiencing excessive itchiness when you stop Seroquel, just know that it’s a result of withdrawal. If it becomes too unbearable, you may want to conduct a slower taper.
  • Mood swings: It is common to experience mood swings when you quit this drug – even if you are not bipolar. The mood swings may be more pronounced and uncontrollable if you are bipolar, but even individuals that aren’t will notice that they may feel angry one minute and hopeful the next.
  • Nausea: One of the most common symptoms associated with withdrawal from Seroquel is that of nausea. You may feel nauseated for an extended period of time until your body becomes used to functioning without the drug.
  • Psychosis: It has been discovered that withdrawal from antipsychotics can cause psychosis. In other words, you may experience hallucinations, delusions, etc. when you are coming off of this medication. Most people don’t experience psychosis when they withdraw unless they have pre-existing schizophrenia – but it is still a possibility.
  • Sleep problems: A person may notice major changes in their sleep patterns and length when they quit taking this medication. One minute the person may have bouts of extreme insomnia and the next minute they may feel extremely tired.
  • Suicidal thoughts: Many people take this medication to help with suicidal thoughts and depression. When you quit taking it, you may feel more suicidal than you have ever felt. This is due to the fact that your neurotransmitter levels are out of balance and you are no longer receiving the drug to help.
  • Sweating: A very common symptom is that of profuse sweating when you stop taking Seroquel. This may be prevalent throughout the day and/or may occur while you are sleeping. You may wake up from sleep in a pool of sweat. Just know that this is your body’s response to withdrawing from the drug.
  • Vision changes: Some people experience pain in the eye and visual disturbances as a result of taking this medication. It has been hypothesized that this and other antipsychotics could lead a person to experience blurred vision even when withdrawing. Some even hypothesize potential “eye damage” as a result of taking this medication.
  • Vomiting: Unfortunately you may vomit a lot when you stop taking Seroquel. This can be a result of intense nausea and/or your body’s way of detoxifying itself. If you feel like vomiting, just know that many people experience this during withdrawal.

Note: It is documented that Seroquel stays in your system for around 1.6 days after you stop taking it.  Once the drug is out of your system, it can take a long time for your neurophysiology to recalibrate itself back to homeostatic functioning.

Seroquel Withdrawal Timeline: How long does it take?

The withdrawal process tends to affect everyone differently – therefore there is no predictable timeline for withdrawal. Some people may fully recover from symptoms within a month or two, while others may struggle with symptoms for months after they take their last dose. There is really no telling how long you will experience symptoms, but as a general rule of thumb, I recommend waiting 90 days before expecting any sort of recovery.

If you have been taking a powerful psychiatric antipsychotic drug for an extended period of time, it is going to take your brain and body quite some time before they fully recover back to homeostatic functioning. Your neurotransmitters and receptors have been altered by the long term drug usage, and your brain will need some time to reset its functioning.

In order to ensure the fastest possible recovery, you can make sure that you are eating healthy, getting plenty of sleep, staying productive, and getting some exercise throughout the day. Exercise helps stimulate functioning in the brain and rids toxins from the body. If you are getting some exercise (even if its light), it will go a long way towards helping you cope with recovery symptoms and recover quicker.

If you have been on Seroquel and would like to share your experience, feel free to do so in the comments section below. By sharing your experience, it helps other people realize that they are not alone and not going crazy.

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{ 704 comments… add one }
  • Tessa Sisson March 23, 2018, 3:04 pm

    I suffered from chronic insomnia for over 15 years where absolutely nothing helped for more than 3 nights at a time. I tried every drug, natural remedies, hypnotism, yoga, exercise – nothing. It seems to run in my family, strangely enough. I was deeply depressed and life became not worth living.

    At one point I would not have minded if I got hit by an express train. I would have drunk arsenic just for the unconsciousness. My doctor finally tried Seroquel, and at last I slept and life improved. 15 years later I tried to come off the drug and was swept back into chronic insomnia, plus the horrors of withdrawal.

    Knowing there is still nothing out there as a long term sleep aid, I am reluctantly going back to Seroquel. I still have some life left and I’d rather enjoy it through guaranteed nightly sleep than the agony of none.

  • Mohammed March 22, 2018, 8:23 pm

    I thank God and everyone here for your inputs. Because of you I decided to stop taking this stupid drug cold turkey which I’ve been taking now for 3 months for my bipolar. It gave me nothing but a good night sleep.

    It masks the bipolar but at the cost of intellectual abilities. I felt slow all the time as if I were high on a cheap illegal drug. This is my 1st week without my 300 mg Seroquel, the first 3 nights were tough.

    I couldn’t get any sleep. Nausea, itching, irritability, etc. – but as time went by the withdrawal symptoms started to disappear slowly.

  • Stephen March 22, 2018, 7:36 pm

    Hello to all, I was put on Clonazepam and Quetiapine starting in 2011 when I had a breakdown had been in deep depression for about 10 years, anxiety and PTSD. I have been taking Clonazepam 7mg per day for the last 4 years + 800mg Quetiapine (400mg twice a day).

    I have been wanting to get off both drugs as I feel they are now making me worse than actually helping. So I went down slowly from Clonazepam from 7mg to 1.25mg slowly(don’t know how long/fast I tapered off) but I am now trying to go slower from what I have been reading.

    I am trying to taper off 25mg per months for each drug but I feel I should stay on Clonazepam at 1mg while I taper off Quetiapine completely. I have noticed that this drug is affecting my memory and also my eye sight has been affected at close range I see blurry.

    I was told it was age as I passed 40 but I feel it in my bones that it is because of both drugs probably. Now I am tapering down Quetiapine 25mg per month as I had a feeling it should be done slowly, but after reading posts on here for the last 2h, I am happy I did that slow to start.

    But now I am scared of what could be coming my way as I taper off regularly (25mg per month). I have been not taking my dosage at specific hours.

    I have been taking them at different time but now I think I should stick to a schedule. I don’t know how I will be without them as I suffer from anxiety, but I know I will be better without this in my system.

    I feel I should maybe go down slower (12.5mg per months) but I don’t know if it is too slow I want to be off this drug now but 12.5mg per month would mean 3 years of tapering off.

    I don’t really have noticeable tapering off side effects right now(that I can associate to the drug) so I don’t know if I should continue to go down at 25mg per month or 12.5?

  • Karen Lowery March 20, 2018, 11:45 pm

    Thanks for all the info. I ran out of my Seroquel last week and couldn’t refill for five days. The withdrawal symptoms were brutal. Since then I’ve decided to stop after seeing my Dr. next month. Currently I’m on 800 mg. I’m not looking forward to the next several months.

    • Dee March 21, 2018, 5:34 am

      The withdrawal symptoms are brutal and please be careful with stopping cold turkey. It’s better to wean off and to have your doctor monitor decreases at small doses over a length of time (been there with stopping all at once and it gets worse over time!).

      I was taking 300mg and am down to 37.50mg after almost a year, but it’s worth it. Please have a plan of action when you need help and don’t be afraid to admit when you need it.

  • Yvon March 16, 2018, 5:29 pm

    I used to be on 200 mgs. twice a day for bipolar disorder. I immediately gained 30 lbs., and after 2-3 years, and because of my age (59), I clearly began to experience a slowness / numbness, and read up on this drug. No wonder my mind is going quickly.

    I eliminated the morning dosage (I used to hit people in the back bumper for no apparent reason but for sleepiness, and I am now off the night dosage (which was done gradually). I simply cannot sleep.

    My main concerns are the meaningless tunes that play over and over uncontrollably in my head 24 hours a day. It’s been 2 days of this, and I’m concerned that I may go mad. Anyone experienced this nasty “song” side effect all night (and sometimes all day)?

    • Dee March 21, 2018, 5:28 am

      I have experienced the weight gain and sleepiness being on this. As I’m tapering off I’ve lost weight, lack of sleep and the repetitive songs. I have had to listen to other songs to get a song out of my head, had to turn the volume up to drown out anything else and to concentrate on what I’m hearing.

      At night I’ve learned to take melatonin to help me relax and to wind down. Also helps to focus on my breathing slow, saying relax in each exhale to fall asleep. Hope some of this helps and to know you’re not the only one feeling this way. It sure helps me!

  • Angela Fluppen March 14, 2018, 4:09 am

    Hi, I am updating. I am four months and one week in tapering. The first month was physical things almost like you have the flu, for me after that it was all about the severe itching, nausea and headaches. I had racing heart beat so bad they did a cardio work up, my heart rate was 140 and up in a resting state for about a month but that has completely gone now.

    I felt like death for a solid 90 days. My doctor and I are conducting a slower taper because I am completely covered in a rash and still itching. Benadryl at night and Allegra during the day is finally helping but for weeks it didn’t even dent it. I used ice packs constantly for awhile.

    Mentally I had about one bad week of feeling strange. I hallucinated some and felt like my head was shrinking (I kid you not). I also felt like I have been plastered to my couch for so long but I am finally getting some energy back. So far I haven’t had insomnia but am still on 50 mgs.

    I just want everyone to know that it will get better. For me it has been slow and brutal at times. God bless!

    • Dee March 21, 2018, 5:44 am

      You’re doing great!!! I understand the things you were going through as I had them too when I first tapered off. The hallucinations are horrible and the shrinking head is weird, I even felt like my brain was being tweaked with!

      Having the numbing and lack of energy cloud being lifted and seeing an end to being on this med is motivation to keep going knowing I’ll be better without it! God bless!!

  • Lynne March 13, 2018, 9:11 am

    Hi. I’ve completely stopped seroquel about 3 weeks ago. Starting yesterday I was feeling nauseous and dizzy and had a “come and go” headache. I was starting to go crazy already thinking I might have some serious illness (might be anxiety that’s kicking up again). Do you think this is part of withdrawal symptoms? But why did I just feel it now? Your reply will be very much appreciated. Thanks.

    • Miilani March 14, 2018, 6:00 am

      I take Seroquel for chronic insomnia. I’ve been taken between 100 to 200 mg for about 15 years. The withdrawals are terrible. If I miss a day, I have symptoms of rapid heart beat, nausea, itching, and so much more. If you went three weeks without any withdrawals, that’s a good thing. Try to hang in there or have your doctor prescribe you something mild to help you with the withdrawals like Wellbutrin.

      • Lisa A March 21, 2018, 9:16 pm

        Try and hang in there. I tapered off seroquel over 4 months reducing by 25 mg at a time – starting with 200 mg once a dosage. Once completely off I didn’t sleep more than 3 hours of interrupted sleep for 2 months.

        Just couldn’t function on that little sleep and didn’t seem to be getting better with time so I had to go back on my original dose of 200mg to get back to 6 hours of sleep a night (not ideal but better than 3) and going to taper off it again over a much longer period with a psychiatrist supervising the process.

        My brain is definitely addicted to this drug. Can’t sleep without it. If you can bear the side effects of the withdrawal go for it, but know from my experience that it can take a really long time for your body to adjust to the absence of the drug.

        Wish I had never taken this drug. Hope all goes better for you than me.

  • Angel C March 13, 2018, 3:23 am

    I’m just coming up on 2 months off after nearly 8 years of 300 mg a day. I want my body and brain back! First time I tried to quit cold and was so nauseous! I tapered down till I ran out this time and had little to no withdrawal. This sex drive killing, penis shriveling poison helped my sleep and focus at work for awhile, but as the years went on it became a new monster. Does anyone know if your sex drive ever comes back? Asking for a friend!

  • Scott March 6, 2018, 12:17 pm

    Hey, I’m Scott. I was put, 6 years ago on 100mg fast release Quetiapine, within a year my super awesome bod was compromised, due to fatigue and apparently according to my GP – the drug itself. I’ve tapered and blah, and found no success. So time to man up.

    I’ve cut them completely off and am willing to take the insomnia, fudge it. Commitment is key. And I want my brain back. Day 3 now. And I am not going back. No sleep, irritable, migraines, and unbalanced moods – it sucks. The key is to keep reminding yourself that the withdrawal is responsible for the moods and keep reminding.

    Knowing that is true keeps a person from succumbing to the symptoms that are affecting your outlook. Keep on truckin’.

    • Hollie March 7, 2018, 11:59 pm

      Good job! I’m like a week and a half into stopping cold turkey as well. It’s tough! But yeah, I try to keep reminding myself it’s the withdrawal that’s causing anxiety, etc. Good to know other people are having a similar experience!

      • Scott March 9, 2018, 11:24 am

        Thanks for the reply Hollie, Still going strong just wondering, knowing everyone is different, I get that. But do you have a personal timeframe on any physical side effects improvement? E.g. sleep, or even heart rate? Any information is helpful. Thanks again for responding.

        • Maddie March 16, 2018, 9:27 pm

          I’ve been reducing for few months now and came completely off 3 days ago and I’ve found it so tough! The anxiety/nervousness/mood/emotion/no sleep are the main issues. I’ve never cried too much. I just wanted to say thanks for the reminder to remind myself that it’s the withdrawal causing this! How’re you getting on now? I hope it’s going as okay as it can. :)

    • Beau March 17, 2018, 9:53 am

      How’s it going Scott? I have tried what you’re trying and it was just too difficult for me, panic attacks in the middle of the night, I had to get up and do jumping jacks just to keep myself from going crazy, until I caved in and had to take some just to ward off the insanity.

      Sarah Quill is a funny drug, I gave a 25 mg pill to my sister a couple of days before her wedding because she was having trouble sleeping – she wasn’t able to get out of bed the next day until almost 4 PM. My dad tried it one night – it was hilarious. I caught him at 3 o’clock in the morning cooking scrambled eggs, he said he was starving.

  • Beau March 3, 2018, 7:09 am

    Hi everybody, my name is Beau, this message is somewhat directed at Christina. I’ve been taking Seroquel for about 10 years now, my doctor had me on Seroquel at 450 mg a night. The reason he put me on Seroquel was for minor, I mean minor bipolar and minor depression. Yeah it helped me sleep, but the side effects were tremendous.

    When I started taking the drug I was 6’ 2”, 200 lbs – I am now almost 300 pounds. I saw the weight gain about four years ago and have tried to stop on numerous occasions. I have tapered down to 25 mg on some nights and 50 mg on others. The problem that I run into is when I try to cut down all the way I have night terrors.

    The best way I can describe this is not being able to sleep, then my anxiety starts building, and building, and building, and building until I can’t take it anymore. Eventually I cave in and have to take Seroquel. I think I’m safe to say that this drug has ruined my life.

    Coming on this message board I was hoping to find a way out, but all I’ve read is: taper down, try meditating, try trazodone. All of this info is very discouraging and a bunch of bulls**t. I don’t know about you, but I will keep searching, especially because the same doctors that got us on this drug should have a drug that could get us off this drug. My hopes aren’t high but they’re all I have.

    • Nicola March 15, 2018, 9:28 pm

      I’m in the same boat. Been on it for 13 years. Let me know if you find anything that helps!

    • Mark March 17, 2018, 12:25 pm

      My friend Brad, a psychiatrist, tells me that exercise is the key to recovery. I’m down from 200 to 50 mg of seroquel at night. The fatigue is terrible but the workouts do help. Hang in there.

    • Dee March 21, 2018, 6:10 am

      One thing I’ve learned over and over is that you can’t go up and down on the dosage, especially from day to day. It will mess with you because it’s not consistent. Slowly taper down. I know you said that sounds discouraging, but it’s better then the night terrors, lack of sleep, and anxiety.

      I told my doctor I’m getting off this drug and I will without being put on any other kind of prescribed “sleep aid”, anti-anxiety like Xanax, klonopin, etc. They’re all as addictive as Seroquel. I’ve gone from 300mg to 37.50mg! And still going. Yes it been 6-9 months, but there is an end! Don’t let this drug continue to ruin your life! You can overcome it!

  • Jessica February 26, 2018, 6:44 pm

    I’ve been taking antipsychotics for bipolar for 3 years. I’ve been on every single one my doctor could name off, but none helped the depression. The first one I was on was Seroquel, and it made me gain 65 pounds in 2 months. I discontinued it and immediately went to something else.

    My new doctor put me on a very low dose of Seroquel about 4 months ago for anxiety and sleep. Then he started increasing it because I stopped my other bipolar stuff due to it not working. I thought because I was on 100mg, I wouldn’t gain the weight. I gained 32 pounds in one month AND I had depression constantly still.

    So I started coming off of it. He told me I was fine to just stop taking it and I’d have no problems. I’m one week into being without it and I have severe itching all over my body. My skin is welting up the second I touch it. I thought I was having an allergic reaction to something until I found this. I’ve dug pits into my skin because the itching is SO BAD.

    For a few days I felt better than I had in years, tons of energy as opposed to being lethargic, happy, and not miserable. Now I’m tired all day until I have to sleep, then I wake up and can’t sleep at all, I’m itchy, and I’m nauseous all the time. I’m not happy at all that my doctor told me to just stop taking it.

  • Beau February 22, 2018, 11:07 am

    I too took “only” 25 mg Seroquel for over 20 years. I slowly weaned myself off of that. The vivid terrorizing dreams lasted around two weeks, but the grueling insomnia lasted 5 months! It was so difficult to work or have any life.

    It’s now 6 months, and I can occasionally fall asleep without resorting to a handful of valerian and melatonin pills. I just allow myself to fall asleep when I need to (sometimes at 6:30 pm after work!). I wind up sleeping maybe 5 hours now, but sometimes, it’s less, and I get up to take the sleep aids.

    I am hopeful it all will return to normal, but it’s taking so long! Just grateful that now I can get SOME sleep at all. I still have some nights when there is very little sleep, but other nights I can have an all night rest. I just cannot plan it- which is why I go to bed whenever I get home.

  • Christian February 19, 2018, 7:37 pm

    I have been on and off antipsychotics since 2009. The antipsychotics I have taken include Olanzapine, Quetiapine and a mix of others given at the various ‘hospitals’. I found Olanzapine worse than Quetiapine. I have been taking a very low dose of Quetiapine (25mg daily) for around 2 and a half years.

    I’ve now been completely discharged and around a year ago I was informed that I am well enough to stop taking these tablets. I have tried 4 times to stop this ‘tiny’ dose and have not gone longer than a week as my early warning signs are back each time. I work full time, I drive, I have a decent house and a loving girlfriend.

    I have found that this medication has destroyed my sleep – While taking it I have extremely vivid dreams but I am ‘asleep’ – When I stop taking it I don’t sleep. I am laying down my eyes are closed but a pin drop would have me out of bed. Since taking antipsychotics I have not had true sleep.

    Without any form of sleep anxiety and paranoia is elevated with me and I can feel that episode creeping up on me and getting sectioned again would only be around the corner. I’m planning to start a family and We just want these tablets out of my life. You may read this and think 25mg is tiny and is such a minute dose that you could just stop but it’s not the case with me.

    I have previously been on 20mg of Olanzapine and 1000mg of Sodium valproate together daily but this Quetiapine is impossible :( Feel completely reliant on it. It’s not just the sleep but the sleep is the biggest impact… any help..? My GP isn’t offering much… 25mg isn’t large enough to phase out slowly…

    • Rosemary February 21, 2018, 4:42 am

      Christian, I understand that 25 mg to most does not seem like much but, it can be to some. Can you consult with your doctor to see if you can cut them in half and taper down to 12.5 mg rather than trying to just stop the 25 mg? Just a suggestion as that is how the started my mother on her anti-psych meds was with a half tablet of a 25 mg.

      I am now demanding that they take a slow approach and taper her off as they are giving her nightmares and flashbacks of traumatic childhood experiences. Plus since she is elderly they are increasing the symptoms they were suppose to reduce. Good luck to you.

    • Dee March 21, 2018, 5:59 am

      I agree with Rosemary- you should be able to cut the 25mg in 1/2. I’m taking 12.5’s to taper off.

  • Raquel February 16, 2018, 1:57 am

    Hi there… I have been on seroquel for over 7 years. My psychiatrist started me with 25 mills. But he knew very quickly when I was manic I really needed to be sedated. So he put me on 600 mills of it. About 2 years ago they cut my dose in half. I didn’t really notice anything. Since then i have had a few visits to the psych ward and stays in the hospital.

    My seroquel has been moved up and down a lot. There are times when I may not be able to take my meds at night… The withdrawal symptoms are horrendous. I am not able to sleep that night. I’m a basket case the next day with a severe headache and a sick stomach all day until I take my meds and go to sleep.

    Yesterday I saw a different psychiatrist as mine is away…. And I told him I wanted off of the seroquel. So he took me down 100 mills for 6 weeks. And then I see him again. He also prescribed me trazodone for sleep. I woke up today tired as ever. Did the stuff I needed to do and then had to lie down. I laid down for six hours.

    My sleep was so disrupted I felt like I was awake the whole time. When I woke up I felt like absolute crap. Sleepy… nauseous… achy… yucky… Emotional… irritable… I am to hear about a new job tomorrow and this is not the time for my body to have withdrawal symptoms. I really hope that they don’t last. My family and I need this job. Thank you for listening to my story.

    • Christina February 20, 2018, 1:11 pm

      Hello, I would suggest, given the current life situation and with you needing this job, don’t put yourself through withdrawal symptoms right now. They only get worse as you taper down. Can you wait to do your tapering during down times maybe? That is always an option. One step at a time. Timing will be everything. And with the support of your Dr, I’m sure he will help you with side effects also. I wish you the very best. Good luck with your job. I hope you got it!!!

  • Angela February 2, 2018, 5:24 pm

    I am almost 90 days in tapering down. The vomiting and body aches have gone but I am still itching so bad I have sores all over me. I am having to use ice packs at night especially. I remember when my doctor put me on this I was plastered to my couch for a long time unable to function. I am experiencing the same thing coming off of it.

    I am still on 50 mg and once I get stable again I will finish the taper. I had to wear a heart monitor for 24 hours because my heart rate was double or more than it should be. They found a leaky valve. I am really struggling with deep depression this last week. It is very deep and I know it is from the withdrawal so I just keep telling myself this will all get better.

    I haven’t left my home much and I don’t know how anyone can do this that has a job or small kids. This drug is demonic in my opinion. Nothing on earth will make me ever take anything less or this again! Good luck everyone.

    • Darlene MacDonald February 18, 2018, 12:06 pm

      I totally empathize with you. I went from 600 mg down to zero in 2 weeks (not very smart of me lol). At first my head seemed clearer, less foggy so I decided to stay off it. Then came no sleep, followed by only between 2 – 3 hours of sleep for about 4 weeks and the last two days 5 hours. The most brutal symptoms are the headache and nausea.

      I have two daughters ages are 13 and 17 living with me and a 27 year old daughter and 6 month old granddaughter. I have been helping them as well and I don’t know how I am doing it. Thank goodness I am stubborn lol. I was getting discouraged and it helped so much that you shared your experience. Thank you!

  • Caroline February 2, 2018, 4:45 am

    I have been on 400mg for about 9 months for bipolar 2. I have been tapering off for a while now. Initially I was reducing about 50mg every 1-2 weeks (until I got down to 200mg). For the last couple of weeks I have been reducing 25mg every few days. I have been experiencing some nausea, but nothing unbearable.

    I am on Lamictal, so haven’t had bit problems with mood. I am now down to 25mg, and am having some trouble sleeping. Again, nothing unbearable. I am wondering now, once I am off it altogether (taking the leap within the next week), how long is it likely to take to be out of my system altogether?

    I am cautious that even once I am off it, there might be a risk of side effects while my body finishes adjusting. It would be great to know whether or not this is likely (I know that nothing is ever completely risk free). Thank you :)

    • Michaela February 23, 2018, 8:43 pm

      I would like to know this as well. I have been on 300mg of seroquel for almost 9 years and I’m trying to taper off. I also have lamictal so my mood has not changed much, but my sleep is TERRIBLE!! I wake up all the time, sometimes in a pool of sweat, sometimes not, I fall asleep just fine but am awake within hours, and I’m tired ALL day.

      I’ve been going down about 50mg each week for the last month, but by 200 my sleep was already wonky. I’m now at 150 but scared to go more because of all the additional side effects I’m hearing about, and fear of not sleeping at all. I’m very relieved to hear it’s a side effect and not a manic episode (I was taking it for depression, but got nervous when my anxiety increased and sleep decreased).

      At least now I know I’m not completely crazy, but not sleeping is killing me. I get bored and anxious easily and every time I wake up, I freak out and get scared that somethings wrong (because I’m not sleeping, not because of the increased general anxiety, though I’m sure that’s not helping).

      But I’m already on other prozac and lamictal and I know the long term side effects of seroquel so I’d rather start coming off now (9 years is a LONG time already). Sorry, that was a long post meant to say, I’m sorry you’e going through this too, but I’m glad I’m not going completely crazy and I really hope I can figure the sleep thing out without having to add, yet ANOTHER medication. :( Everyone’s support is appreciated.

    • Indigo February 25, 2018, 7:06 am

      Hi Caroline, my name is Indigo. I am on 450 mg and if I’m really tired I take 600mg. I have had enough of the stuff. I will do my own little write up here but I am going to try start at 400mg and reduce 50mg a week. Oh and I have been on it for 3 years. I have responded to you as to maybe a pal idea might work by checking in with each other as we seem to be on about same amount. Hope you are into that and are ok with throwing ideas around. INDIGO

      • Caroline March 1, 2018, 11:23 pm

        Hi Indigo, I am happy to chat. I think that in my original post I was down to 25mg. That was when it got tough. I stopped for a week, but that was too sudden. I brought it down to 12.5 for a week or so, and now am on 6mg. The last couple of drops have been really painful. I have begun to suspect that the medication (and therefore any changes to those meds) mucks with gut bacteria.

        This is because I had loads of food intolerances years back, and a lot of what I have been experiencing is similar. There is also increasing evidence concerning the gut and mental health – most of the serotonin on your body (I have heard up to 80%) is in your gut! So, I am trying some dietary adjustments.

        Every day I am eating good quality yoghurt that is high in probiotics, lots of fibre (which is high in prebiotics – helps make a cozy home for the good bacteria), and trying to drink lots of water. All that seems to be helping somewhat. Of course though, dietary adjustments can take a while to have full effect. I figure though, it is healthy stuff, so can’t hurt.

  • Mary Anne February 1, 2018, 2:38 pm

    5 months after quitting a 14 year daily low 25mg dose of Seroquel, I still have insomnia. In order to sleep, I take a nightly dose of the following: 5 450mg of valerian, 20 mg of melatonin, and 3 Benadryl pills. This does not always work for the entire night either!

    I have had some success also with “Nighty Night tea”, but then I wake up in the middle of the night due to having to pee. I have experimented with many ways to fall and stay asleep. Please read up on taking herbal remedies for sleep, because you can overdose on the “natural” stuff too.

  • Lisa January 31, 2018, 6:17 pm

    OMG – I wish I had never been prescribed this drug. Was on 200 mg for sleep for 15 years. Have weaned down to nothing over a couple of months. Have had six weeks on miserable insomnia since getting down to 100 mg level.

    Going to my doctor tomorrow to see what can be done as I am getting almost no sleep at this point even though I have been off the drug completely for 5 weeks. Considering going back on the drug at some level and redoing my withdrawal over a longer period of time but don’t really want to do that.

    However I just can’t function on 2 to 4 hours of sleep a night that includes waking up every hour or two during that time. My best wishes to all of you going thru the withdrawal process like me.

    Had been helpful to know others are going through the same tough battle to quit like me. Hope we all get off this drug safely and finally and never take it again.

  • Denise Shepherd January 29, 2018, 5:32 pm

    My doctor put me on this med to induce sleep since I was having difficulty falling asleep and staying asleep. She did not inform me of the side effects or dangers of taking this drug. My business suffered since I was not capable of keeping up with it.

    Not knowing what was going on, my doctor, put me on more medications when complaining about the side effects, my understanding was that it would help with sleep patterns. I feel very betrayed by my doctor. I am now going to attempt to wean off at a slow pace.

    I have heard others that ended up in the hospital in doing so. My flight for fight is very high, my fear and frustration is great. My eyes are messed up along with my blood pressure which has never caused me a problem before, more meds, more bad side effects. My relationships with my family are totally ruined because I would run away at the slightest comment from them.

    Right now I am very angry from being fooled by my doctor. None of my family will speak to me. I am alone. This challenge is another blip in the road of life. So here I go…

    • Christina February 20, 2018, 1:23 pm

      Hello, Make sure you’re tapering slowly. Very slowly. Over a period of time, I’m talking years for some people. I was one of them. It took me 2 years to get off 300mgs. I also felt betrayed by my Dr. But honestly, they’re only doing what they think is best to treat our symptom we tell them, at the time.

      The best thing you can do, and I did, was meditate. Love yourself fully. Be patient with yourself and the withdraw process. Also, manage your fight and flight responds using a method like CBT (Cognitive behavioral therapy) or DBT (Dialectical behavioral therapy). Or just Mindfulness techniques. Or a combination of all. Drink TONS of water to flush it.

      And please do it under your Dr’s supervision. The last thing you want is a hospitalization and more meds added due to a temporary crisis situation you’re experiencing from the withdraw. So what saying is, keep your Dr in the loop. If you feel he doesn’t support you, be patient and seek another Dr who will help you. This whole process requires patience. For yourself, for the Dr’s and for the withdrawal process. I hope this helps.

  • Nick January 25, 2018, 4:45 pm

    Seroquel at 100mg made it difficult to think and process information. I found that Xanax helps with the withdrawal symptoms. No doctor ever warned me about the extreme side effects that come from discontinuing the medication. The withdrawal is severely painful and disturbing. Life is better without meds!

  • Midoriana January 18, 2018, 9:11 am

    I took my last Seroquel (300mg) on Sunday. I actually wasn’t planning on doing this, but we had a snow storm and the.clinic has been closed since last Friday. It is now Thursday and I really haven’t experienced any withdrawals (been taking Seroquel since spring of 2015 for Bipolar one). The article said it takes 1.6 days for the drug to get out of your system, so I assume that I should have some effect at this point.

    The only difference is that I want to sleep all the time, and not in a depression or fatigued type of way, but more in a way that the dreams are so vivid that I prefer to experience them over actual consciousness. Has anyone experienced anything similar, or know when I will be hit with withdrawals?

    • Mary January 19, 2018, 3:32 am

      Those “vivid dreams” you describe are often mentioned in this thread (and others) about Seroquel as initial withdrawal symptoms. I endured horrible dreams for a couple weeks. You might have slight symptoms as you took the drug for less then 2 years. I took it for 20 plus years, and have endured several months of insomnia.

      If you do not take the drug, you might get more withdrawal symptoms. Read this thread even though it’s very long. Never stop psyche meds cold turkey! Even with gradual weaning off, there can be unpleasant withdrawal!

  • Stevenson January 16, 2018, 7:13 pm

    I’ve taken a 600mg dosage of Seroquel for three years. I titrated 100mg a week. In retrospect it was too quick of a discontinuation. I should’ve been more prudent and allow a longer length of time to wait for its removal of my dependency. Side effects include a smorgasbord of itself; from insomnia, acute and chronic anxiety, fickle emotional responses, weight loss, and numerous others.

    There doesn’t seem to be a solution for restful sleep. However, to quickly attain normal sleep do not put yourself in stress inducing situations. Allow your body and mind to heal and not be perturbed.

    It was a long endured and difficult experience. With such a high dosage, and the short period I gave my self to come off it, I’d say withdrawals last me around a total of twelve months till beginning to subside.

    I suggest anyone going through this to not go cold turkey, and to give yourself 2-3 years to come off it completely. From all the research I’ve done, the ones who successfully discontinue this medication and have had no withdrawal symptoms are the ones to give themselves an extensive titration period.

    Anyone questions please comment, I am willing to share and give feedback.

    • Phil March 14, 2018, 4:09 pm

      I have been on this drug since 2011. Basically, I began at 100 mg. Then the Dr. brought me up to 150 mg. I went down to 100 mg. as the sedation effect was too much. I was coerced by a PA into getting on 200 mg. and went up to 300 mg. I gained 40 pounds. Finally they took me cold turkey off of it and switched me to lamictal.

      I then got pancreatitis. That was enough for me. I went nonfat and veggie and tamed the pancreatitis. Then I lowered my dose to 200 mg. THEY TOLD ME QUETIAPINE WASN’T ADDICTING AND I COULD JUST QUIT IT ANY TIME. SORRY, SUZIE Q IS MORE DANGEROUS THAN HEROIN. I tried to taper at a rate of 25 mg per month. I got impatient and reduced too fast (about two weeks each reduction) down to 150 mg.

      Now I have withdrawal symptoms even though I ran like hell back from 150 mg to 175 mg. and back up to 200 mg. The withdrawals got pretty bad at 150 mg. Nausea, increased heart rate, insomnia, lethargy, anxiety, sweaty palms… still I am having them and it’s been about three days since I got back to 200 mg. The whole problem is that they purposely designed this drug to string you out for $$$.

      I am now doing supplements and trying to get withdrawal free before I taper down AT A CRAWL… 6.25 mg per month. It’s almost a three year plan. But I’m 61 and sure want off this poison! What gets me SICK IS THE HOLISTIC REHABS that know how to get you tapered off and healthy etc. only take PRIVATE INSURANCE and mine doesn’t count. What a totally screwed up system.

      The drug companies, the doctors, and the whole “for profit” system gets me sick. The only way to get off it without the amplified horrors of withdrawal is at a rate of reduction of 6.25 mg. per month. Even then you will have withdrawals, but they will be far less than those going by the 10% per month or 10% per week plans out there.

      They are horses**t. You jump into this rabbit hole, but you have to literally slowly climb out. Very slowly. With supplements: Amino Acids, Omega 3s, CBD Oil, etc. Vegan food… I will try to get stable at 200 mg. I may have to go up to 225 mg as my sleep has been disrupted.

      Vivid horrible dreams recently. Once I am at the stable level, the tapering will begin, but at a crawl. Literally a small scrape off of a pill per month. Very small. God bless and good luck!

  • Jeffrey January 16, 2018, 1:14 pm

    Many of the comments here link seroquel with a racing heartbeat. With me it had the OPPOSITE effect. I love to run and was running 5 miles a day when I was prescribed 300mg of this drug. Afterward, the first time I ran I became so dizzy that I fainted and face-planted on the concrete. My resting heart rate is around 53 and has been as low as 42.

    I’ve been off the drug for about a month but the whole time I’ve only been able to run a quarter mile before I feel like I’m dying. When I check my heart rate, it’s very low and won’t rise with exercise. I sure hope this isn’t permanent. Has anyone else experienced bradycardia with this medicine, especially while exercising?

  • Nat January 16, 2018, 5:58 am

    Was scaled up to 200mg and then backed myself off, all over a time of 18 months. Stopped taking any 6 months ago.

    Immediate side effects: Insomnia (went away after about a week, slept fine since)

    After a week I started getting frequent wide muscle spasms, severe itching and tinnitus. Six months later: none of these side effects have gone away and the lingering feeling that they are permanent (which with these drugs is technically possible) has made me fall into a state of depression that was worse than before I was taking it.

    To anyone reading this who is thinking about taking it: Don’t. You will regret it.

  • Sabina Frank January 15, 2018, 1:41 pm

    I have been on Seroquel for 8 years. Way too long. Am down from 150xr daily to 50xr every other day. Hardly any physical withdrawal but lots of anxiety which affects my breathing. I am a chronic asthmatic and find it really hard to tell if it is really my asthma or anxiety. Scary.

  • Peyton January 3, 2018, 9:32 pm

    Just a warning: do not underestimate the itching! I didn’t know it was a symptom of withdrawal and spent a year trying to figure out why I occasionally randomly started itching before finding out that it was anytime I missed my medication for a few days (for example, if you are having trouble getting the prescription filled or insurance has changed).

    This is EXTREME itching. I would claw myself until I bled because the pain was more bearable than the itch itself. It also occurs everywhere all over your body and will drive you crazy. After trying every OTC itch cream or lotion I could find only to realize none of them helped in this particular situation, I found the solution..

    Use an antihistamine (I specifically use Benadryl). I don’t know why or how it works, but it does. Just know that there is hope and there is a way to manage the symptoms that doesn’t involve compulsively and pathetically crying into the oven mitts you’re wearing to keep yourself from scratching.

  • Raven December 27, 2017, 2:42 am

    I have taken several days to read all these comments. I have been on 600 mgs of Seroquel for a little over 20 years. Back when I began taking it, not much was known about long term side effects and withdrawal. I gained 75 lbs on Seroquel, my cholesterol is high, my blood pressure is high, and I’m prediabetic. All caused by Seroquel.

    I tried cutting my dose in half and the withdrawn was so bad I began hallucinating. I found this site and I’m so glad to know I’m not alone. I resumed my usual dose until I could speak with my Dr today. He is a great doctor, I’m very lucky. I told him of my experiences and shared this site with him. He agrees it is best to taper VERY slowly.

    And we are going to try reducing the Seroquel by 10 mgs every month or so. He mentioned that if I need to, I can taper even more slowly, and he made sure I understand that I can talk to him if something isn’t working and we will come up with a plan to address it. I plan to begin my taper at the beginning of next month when I get my meds refilled.

    I’m very very nervous, even scared. I know I have a rough few years ahead of me while I work to completely get off of Seroquel. I will keep a journal of my journey. And I will come back to this site and share my experiences. If anyone would like to talk privately about our experiences with Seroquel, please email me at [email protected]. I would love to hear from others going through this.

  • Paul March 29, 2017, 1:54 am

    I started on 100, 200, 800 mg of seroquel cuz apparently I had schizophrenia. From the beginning is started with it very badly. I could not breathe thru my nose and when I wanted to breath thru my mouth, my mouth would get very dry, plus I would get cramps in my legs which instead of helping me sleep it kept me awake at nights. Due to Seroquel, I was diagnosed with sleep apnea which is very dangerous.

    I trained myself to breath thru my nose and stopped snoring but the side effects such pain on feet and the cramps, breathing problems, heart pounding really fast, was so unbearable that I did not know what to do. I decided to taper it slowly and 6 weeks ago I was able to downgrade it to 300 mg. Amazingly, all the pain went away. Now I can’t hear my heart pounding and I don’t know if thats normal.

    It’s been six weeks and I manage to sleep only a couple of hours per night. I honestly don’t know whats going to happen to me due to the lack of sleep. Interestingly, I feel energized during the day, no fatigue, no vomiting, no headaches, no diarrhea, a bit of runny nose but it will go away, and concentration problems. I also stopped biting my tongue and the walls inside my mouth which occurred as soon as I started falling in sleep, waking me up at nights.

    I must confess that while reducing it I also used alcohol – which I don’t recommend to anyone unless you really know how to do it. As I did not want to overdose myself when I got drunk, I would reduce from 800 to 25 to keep me sleeping the entire night. Good side effect? I would get very sexual for several times by next day. But the next day I would get back to 800 mg and that’s when that fun would begin.

    I could not breathe and the pain on my feet was killing. I would do my praying several times before going to bed and even wrote my will just in case. I really thought that something was going to happen in one of those times, for years I would say. I truly believe in God and would ask him every night to help me with all my heart. Well, one evening it occurred me to take 600 instead of 800 and interestingly, the side effects decreased.

    I kind of liked it and decided to reduce it like that slowly until I reached to 300. Problem? When I decided to stop alcohol 6 weeks ago I could not sleep for 2 weeks at all, only a couple of hours per night now. I feel good cuz the pain is gone, my sex drive is back and the alcohol is gone. I feel proud for achieving this. I am determined to stop alcohol and eventually will completely get rid of quetiapine.

    Oh, I also stopped Clonazepam 6 weeks ago which gradually eats your memory. I guess I am just so strong, but not without my love of God. I think without God I would not be here now talking about this proud achievement. I really suggest that you give him a try. I promise you. I think my sleep will eventually come back.

    I have faith. Does anyone have suggestions for the sleep issue? Finally, if I knew about these bad side effects of seroquel I would have never tried, NEVER. For those deciding, think first and talk to your Dr, second opinions are always suggestible. Going cold turkey can make you suicidal. I tried it too. Good luck to you all, will pray for you, please pray for me. Paul :)

  • Carmel March 22, 2017, 2:47 am

    I have been on Seroquel for over four years. I can’t take regular antidepressants due to them causing suicidal ideology. However, the Seroquel is literally killing me now with uncontrollable high blood sugar and off the charts triglyceride levels. So now my med provider and I are starting a slow taper of 25mg every three weeks at least until my blood sugar and triglycerides are under control.

    She may decide to keep me on a low dose as long as it’s not having a negative effect on my general health. The first taper down dose started last night. I will keep you posted on what, if any, withdrawal effects I may experience and how I deal with them.

  • Kelly March 16, 2017, 3:59 am

    I have been taking 600mg of Seroquel XR for a little over two years. I have been diagnosed with bi-polar and PTSD. I was suffering from late night manic episodes. I would frequently go 2 maybe 3 days with no sleep. Even taking 4 Tylenol PM only gave about 4 hours sleep. Since I have been on Seroquel I have no energy, no ambition, and I have no emotions.

    I have added 100lbs and have had issues with my stomach and my heart and I am now as depressed as I was before. I have gone 2 days without the med a couple of times and I feel like I am about to die. Migraine level headaches, stomach pains, vomiting, muscle pain, and sensitive eyes.

    I have 4 kids and want to have the energy to keep up with them. I take 2-300mg pills every night. I want to come off of this and I am trying to figure out the best way to do it. Cold turkey is not an option for me as it puts me down after day two. Any help would be greatly appreciated.

  • Phaedra March 14, 2017, 9:35 pm

    I’m posting an update to a post I made here in Nov. I was on 25 mg for 2 years. I tapered off this low dosage over 6 weeks and my withdrawal side effects like headaches, nausea, heart palpitations lasted for 3 months after my last dose. This stuff is poison! And whatever you do, no matter the dosage, do not stop cold turkey.

  • Michael Mandra March 13, 2017, 11:02 am

    Why would anyone want to quit seroquel cold turkey? The withdrawal symptoms are probably so much worse then tapering off. I was on 300mg of seroquel for about 3 years. It didn’t help me at all and I didn’t like what it was doing to my heart. It also made me completely numb and indifferent to everything.

    I tapered off 50mgs at a time it took about 3 & 1/2 months to get off them but the withdrawal symptoms were very mild. Each time I went down 50 mgs. I would get headaches, itchiness and blurred vision for about 2 days then the withdrawal symptoms went away. Don’t go cold turkey just taper off trust me.

  • Cynthia Rose Hubbard March 4, 2017, 2:48 am

    I have been taking Seroquel for about 5 years now. Within those 5 years, I have quit cold turkey twice. Bad idea people!! Both times I chose to, not by doctor’s orders.

    Both times I got put into funny farms, sorry if some of you feel offended by my terminology… I quit solely because I felt more like me. I thought I didn’t need Seroquel anymore. Well, Seroquel was why I felt more like me.

    I am currently back on the medication. Have been for a few days now. If you are being prescribed this medication and feel like you want off of it – please take my advice. Speak with your doctor about it FIRST. The side effects can be detrimental!!!

  • Leo January 23, 2017, 9:12 pm

    If you’re reading comments to help you or a loved one decide whether or not to go on Seroquel, especially as a low dose ‘adjunct’ for depression treatment — DON’T DO IT. I was put on Seroquel about 6 months ago, building up to a dose of 300 mg over a few weeks, to supplement my regular dose of the SNRI Effexor (which I’d been on for about 2 years) to treat my MDD (Major Depressive Disorder).

    Adding the Seroquel helped slightly with my mood and depression, but it also made it nearly impossible for me to wake up and get out of bed in the morning; most mornings I felt paralyzed laying there, like I wanted to get up but couldn’t actually move. My sleep patterns and energy levels were thrown off completely while taking it, and I was hungry all the time and gained about 15 lbs. in 2 weeks — bad news for a diabetic. So my new psychopharmacologist suggested getting off both medications and maybe trying an MAOI instead (still undecided about that part).

    Withdrawal has been a living nightmare. I’m not sure what’s being caused by lingering effects from tapering off the Effexor (which I did first) and what’s being caused by tapering off the Seroquel (which I did next over about a 4 week period; I’ve been off it completely for about 10 days now) — there’s a lot of overlap in the lists of withdrawal side effects for both drugs — but the main side effects of withdrawal are hitting me now and they are making me miserable.

    I feel concussed. I can barely think, let alone concentrate (it’s taken me 3 hours so far to write this comment). I have a twilight sensation in my head at all times, like I’m not getting enough blood to my brain, and just turning my head to the side leaves me lightheaded and foggy. I am crying all the time, at the slightest provocation. I am tired all the time and want to crawl back into bed every 5 minutes.

    I am extremely irritable. My limbs feel like they’re made of lead and my joints feel creaky and odd, like I have no control over them. Just climbing one flight of stairs leaves me aching and breathless and sets my heart racing. I am periodically nauseous and feel the need to throw up but can’t. My vision has gotten much worse — extremely blurry.

    My dreams have gone from vivid and kind of antic but entertaining (like another commenter here, I would frequently wake up laughing in the middle of the night), to being just as vivid but deeply, deeply upsetting and bleak. They’re not exaggerated or grotesque in a nightmarish way, but they are profoundly dark and disturbing — all the things I’m most concerned or troubled about in life play out in excruciating detail while I sleep, and I’m somehow conscious that I’m dreaming but can’t wake up or stop them in any way.

    And the worst withdrawal side effect of all is this: while I was deeply depressed before and would occasionally think about suicide as a way out (which is why Seroquel was added to my treatment), I was thinking about death but not feeling in any way compelled to act on that feeling. But now I am thinking about death uncontrollably, ruminating about it constantly, like it’s the only concrete thought my mind can actually form. It’s scaring the sh-t out of me.

    Don’t take Seroquel and don’t let Seroquel be prescribed to anybody you love, if you can help it, at any cost.

  • Jane January 11, 2017, 1:05 pm

    I was on 300 mg Seroquel for 12 years for treatment of diagnosed bipolar disorder. For 10 years I had no doctor supervision, as my pdoc declared me stable after two years and only required me to check in “if” I experienced any mood symptoms. About five years after I had stopped seeing my pdoc, I began to reflect: I had had no mood episodes. NONE. I began to wonder if I had received the right diagnosis.

    Another three years, no mood episodes. I asked my family doc if I could consider reducing the Seroquel dose because I was noticing impaired memory function. I reduced first to 150, then to 100 with no noticeable mood effects. Because of a mixup with my pharmacy, I have now been without Seroquel entirely for a few days.

    Still no mood effects, but I’m experiencing (mild) physical withdrawal symptoms. Just putting this out there, because I suspect I was prescribed Seroquel when it was new and fashionable and perhaps it wasn’t really helping me all that much, after all.

  • Karen Smith January 10, 2017, 8:16 pm

    I’ve been on Seroquel since August 2015. I was in a car accident which gave me a concussion and a bad movement disorder. All of my Drs. told me I had “Conversion Disorder” and prescribed a Psychologist/ Psychiatrist, who placed me on Seroquel for sleep. I started to taper (from Seroquel 300 XR to 25mg) over a couple months.

    I have always had issues even when I would forget for just one night. The next day I would feel like I had a very bad hangover; headache, nausea, sleep deprivation, and very sluggish. I took my last 25mg pill two days ago thinking that the tapering would stop or dull the symptoms.

    It did not, at all. I still feel horrible, my mind is still foggy, my memory is almost non existent, and I am at my wits end. I am going to try to join a gym, hopefully this week to help combat this feeling of dread. Wish I was never introduced to this damn drug. Makes me feel so stupid and flighty.

  • Anna Sambrone January 9, 2017, 3:36 pm

    I have taken Seroquel for about 5 years at 200 mg. My doctor gave me Latuda to replace it but did not talk about the withdrawal of the Seroquel at all. Withdrawal started immediately!! I’m only on day 2! I was so relieved to read that others had my symptoms of cold turkey even though I have another antipsychotic to replace it.

    Body pain, nausea, head aches, insomnia, and mental discomfort! I hope that some home remedies and the knowledge of all your input will help. I also plan on starting an exercise for 10 min a day.

  • michael January 5, 2017, 5:35 am

    Hey guys, So it’s been about 2 months since my last post, and just over 3 months since I stopped taking Seroquel, and I thought I’d give a little update on my experience. From all the research I knew that minimum recovery time from withdrawal was 90 days, so I was really looking forward to January 1 2017 (3months for me), and was hoping I could ‘tick’ this episode of my life of the list.

    Um…not so much. So for me the biggest symptoms I faced were acute insomnia and nausea. In the first 2 months I couldn’t get more than 2-3 hours sleep a night! My last posting described the lack of sleep as physically painful. Now I get 5-6 hours of broken sleep.

    Last night my sleep was ended at 2am with me waking up knowing that I was going to die…good old impending sense of doom had returned (he and I go way back). I am also getting nauseated at least 2-3 times a day. I have absolutely no ability to concentrate on ANYTHING, and my balance is still way off.

    Having said all that, there is a definite overall improvement. So I just wanted to let you all know, it does get better. Hang in there… I can see the light at the end, or at least a faint glimmer of some kind.

    Anyway, I’ve documented my withdrawal, combined with a little guidance advice on YouTube and hope it may help other out there: https://youtu.be/eZ2lbLFeUFQ Thanks, Michael

    • Anna Sambrone January 9, 2017, 3:37 pm

      Thank you for posting!!

  • Worried Mum January 1, 2017, 7:09 pm

    My son (age 34) was on Quetiapine for about 3 years, 175mg. He tapered off slowly and took his last 25mg 2 months ago and has been through hell since. I realize now that he should have tapered the last 25mg slower, he did take every other day for a few days but then stopped. His anxiety and panic attacks have been really bad, trouble sleeping, plus much more.

    He had put on weight but has now lost more and probably now weighs less than 8 stone. This has mainly been due to throat tightness caused by the anxiety so now lives mainly on soup. Over the last few days he has slept slightly better and been a little less anxious but now depression has set in. He has little energy and has become over focussed on his breathing and heart and is paranoid that he will stop breathing or that he will have a heart attack.

    He cannot work as everything he tries to do is too stressful. We are trying to make sure he goes out for a walk daily but doesn’t manage to go very far. He is taking supplements but we have to find them in powdered or liquid form as he cannot swallow pills. I just want my son back. Can we please have more people coming back on here to say they are fine? Did anyone else go through similar and how long did it take to get better?

  • Cy December 30, 2016, 5:37 pm

    I have read many, not all of the comments on this site and for the most part, there are many who have been on moderate to high doses of quetiapine for months to sometimes years. My comment is about even short term use at low dose and what I personally, have been dealing with (of course it depends on an individuals physiology) and how that continues right now. I have had PTSD for many years and have dealt with it through a therapist and am making progress.

    Couple months back, I had a bit of a breakdown from what I thought were PTSD related issues and it turns out they were not. I saw a doctor and was prescribed quetiapine low dose (25mg) to help me sleep which it did and took it for around two weeks (ish) until I came to understand that my issue was not PTSD related (I was associating) and am now dealing with the issue separately. The quetiapine was also making me feel quite bad during the day, so I felt I should just get off this medication altogether.

    As it has only been around two weeks and low dose, it should not be a problem. I was told to ween by cutting the 25mg in half for one week and then 12.5mg for one week and then completely off thereafter, which I did. Again, everyone’s physiology and sensitivity to medication and withdrawal is different so this may not be typical, but I have to tell you, this has been a very difficult experience coming off this drug, even at that low dose for only a two week duration.

    I am now in my fourth week since quitting and I have had insomnia for several nights to begin with, and since then have gotten better. I have had very high anxiety with some moments of paranoia and the symptoms seem to come in “waves”. There have been days where it has not been too bad and then the next day the anxiety seems to return along with other body symptoms and then it will subside.

    I can still function OK but it is very difficult at times and very concerning, because I was only on this stuff for two weeks and at low dose! How can that happen??!! My expectation (as I’m sure many people think) is that I should recover in about the same period of time that I took the medication and that has turned out to be completely wrong, there is no timeline, so don’t put any timeline on your recovery.

    It will take as long as it takes and as I said, people are different so your experience may be completely different than mine. The only thing I took coming off the quetiapine is high dose vitamins and amino acids to help, which it has. My comments are not meant to frighten or concern those who have taken this drug longer and at higher doses, it is meant to inform people of the power of this drug and how that seems to be taken very lightly when it’s prescribed by most doctors.

    It is a very powerful drug that should only be prescribed to those it is intended to treat and even at that, it should be used with extreme caution. I think my recovery will take several more weeks to feel more consistently better every day, and this is a lesson to me about medication in general, but particularly seroquel. It may have its purpose but it is far more powerful and long lasting than is told to people when it’s prescribed.

    I sincerely hope that everyone going through this will remember, it’s not you, it’s your system trying to recover back to normal, even though it may not seem like it at the time.

    • Cy January 8, 2017, 1:50 am

      4 weeks, 6 days after being completely off seroquel. The anxiety seems to have gotten worse and intense, particularly after getting any form of exercise or physical activity. I’ve been told it’s whats called a “med release” which can make the symptoms much worse. I am taking more of my supplements to offset the symptoms and continue to ride it out.

  • Anna December 30, 2016, 4:34 pm

    I was on 300mgs of Seroquel XR for 7yrs. It has taken me a full year to taper off completely. I have now not had any Seroquel in my system for 3 months. During the year tapering, I experienced mainly the the following symptoms: nausea, dizziness, irritability, sensitivity to light and sound, agitation, insomnia (waking stimulated… almost electrically charged it felt like), decreased appetite… and the list goes on, but those were my most prominent.

    Now that I’ve been off the drug entirely for 3months, I am experiencing anxiety to the point of my stomach is in knots. Crying fits (in the middle of stores… very embarrassing). Extreme sadness for the state the world and people are in. Zero appetite. Paranoid delusions… fueled by anxiety and vice versa.

    But some good also, I’m seeing the beauty in life and feeling invigorated and excited to live it. But the paranoia and anxiety are debilitating. Especially the paranoia. So, it’s mainly the psychological effects I am contending with now.

    (NOTE: I never experienced paranoid delusions before taking this drug). I refuse to give in and start taking this drug again. I know the effects and know the dangers of long term use. (In my personal opinion any use is dangerous). Although, I really hope my brain readjusts very soon. Has anyone else had similar experiences?

  • Ashley December 30, 2016, 3:50 am

    I am decreasing a 100mg per week from being on 300mg for almost a year. I am miserable. Is anyone else having hot flashes? Horrible body aches? Please help.

  • Jordyn December 22, 2016, 5:52 pm

    I’ve been on Seroquel for 2 or 3 years. I’m 22 years of age. I’ve begged my doctor over and over again to take me off this medicine and he keeps on upping my dose. I’m not crazy!! There’s nothing wrong with me. I have PTSD. My parents don’t wanna deal with me so they use this drug to shut me up. I have come to the last resort of quitting it on my own.

    I have been experiencing withdrawals everyday. Violently vomiting, extreme nausea, extreme headaches, my whole body shakes & aches. From 300mgs I’ve lowered my dose to 50mgs. I cut my pills with a razor blade so there’s no way to know for sure how many milligrams I’m taking. I’m going to lower my dose once again to 25 mg. My question is how long should I stay on the extremely low dose before I quit altogether?

    • Cyn December 25, 2016, 5:44 am

      So sorry that your doctor is upping the meds when you are asking to be weaned. Are you able to work with a different doctor? With the severe withdrawal symptoms and not knowing how quickly you went from the 300 mg to 50 mg makes me wonder if you should stay at 50 mg until you adjust to that better.

      This is a tough med to get off of and going slow seems the softer, easier way off. Now that you started the weaning on your own, I can only suggest that you allow a decent spread of time between the decreases. What a decent spread of time means for each of us is different when dealing with individual systems coming off of the seroquel.

      I did close to a month on the 25 mgs and ended it there because I was already enduring the itching and wanted to finally get past it. Had I been able to, I would have cut the 25 mg in half for a few weeks. Be patient with the process. Give yourself as much time getting off as you need.

      Your body and brain are used to the chemical changes of the seroquel and will require time to change back to the normal functioning it once had. Do you have a support system in place to deal with your PTSD? Are there any groups you could get involved with where you can connect with others who also deal with PTSD or medication related issues?

      A group setting is a great place to hear how others have dealt with a myriad of issues. The benefits of having nonjudgmental group support are many along with knowing that others have your back. Also the experience you bring to others is priceless. Good luck with taking the best care of yourself.

  • Sandra December 21, 2016, 2:46 pm

    Hi, My daughter is finally off the Seroquel. I brought her down from 350 to 200 to 100 to 50 and now she stopped one week ago. She’s getting the full withdrawal effects of the drug: headaches, flu like symptoms, itching, anxiety, nausea, insomnia as well as heart palpitations. However, she’s more of herself lately, she can think better and remember things better she’s less irritated and her appetite has decreased (this drug put about 15 pounds extra in 2 months).

    My poor daughter has been through so much ever since she was diagnosed with “unspecified mood disorders” 4 months ago at her short age of 12. I am taking her to an acupuncturist for her sleep and anxiety problems. She’s now taking melatonin with serine and Gaba along with fish oil, B complete, and a bunch of other natural supplements.

    She’s also on a strict diet very healthy staying away from sugars, eating all organic fruits and veggies lots of fish specially wild cough salmon and organic meats. She also working out 3 to 4 times per week and exposing herself to more natural sunlight in the early mornings. Her cycles are decreasing time/intensity wise she seems to control her moods a little bit better on her own.

    The Seroquel was making her hungry, forgetful, anxious and unable to focus or do the things that she used to do creativity wise. Her last episode lasted one week compare to the first two episodes. There’s a cure for all this chemical imbalance problems but it requires lots of efforts it’s a total lifestyle change.

    But I rather have my daughter on all this natural supplements, good diet and exercise than have her on all this crazy drugs. Which in time will destroy her brain, kidneys, thyroid, personality, etc.

  • Elizabeth December 21, 2016, 1:11 am

    Thank you all for sharing your stories! It is good to know I am not alone. I have been on Seroquel for 7 months now. It helped to calm me down in May after a psychotic episode, but now I don’t need to be on it.

    Now, I am taking Niasafe (a non-flush form of Niacin) B vitamins, 5HTP, Magnesium and probiotics and amino acids to help my brain chemicals normalize and heal. This is my second time on Seroquel. (The first time was 8 years ago) and I don’t remember any withdrawal symptoms last time I took it. This time, I started with 25 mg and worked up to 100mg twice a day.

    I would get so drowsy when I took it in the day, and I couldn’t focus on anything. So I started taking just one pill at night. My doctor gradually tapered me back down to 25 mg. I have tried a few times to stop taking the 25mg and I had problems falling asleep. That got me worried.

    I am planning on using melatonin if this happens again. I am on my third day off Seroquel. I have experienced some of the withdrawal symptoms, feeling nauseated and not feeling like eating. But not at extreme levels.

    • Sandra December 21, 2016, 2:59 pm

      Elizabeth, Try the melatonin (5mg chewable peppermint) with Gaba and Serine. We use the Source Natural brand. This is working for my daughter she’s sleeping better from 8 to 10 hours and only waking up once or twice. For the withdrawal symptoms try B Supreme and lots of water to flush and clean your body from the drug.

  • Tony December 18, 2016, 2:14 pm

    By my own experience. 5 years using Seroquel for generalized anxiety disorder. Started with 200mg dosage at bed time. Then along with the time, reduced to 50mg a day, 1/2 of that dose, then 1/3 and finally 1/4 for the last 3 months. However, when dropping it totally, I could only sleep 2-3 hours a night.

    I then tried the middle, inside green part of the lotus seed (EMBRYO NELUMBINIS). The dried ones that look like tea. I believe you can find it in most Asian or Chinese supermarket. As for me, I could find the fresh ones and fried it by myself on a pan. Just use it like Chinese tea.

    One teaspoon in a mug of very hot water. You then can add as much hot water as a gallon to it as you like for drinking during the whole day. This simple but well known oriental medicine did help me to sleep again, soundly at night. Not feeling sleepy during day time, though. Hope this helps somebody.

  • Megan Ayers December 18, 2016, 12:26 pm

    Thanks for the article! I have been taking 100mg for about 3 months and didn’t get a refill before I ran out. This is my first night without it since I started taking it and I cannot fall asleep. I will be weening myself off of it when I get my next bottle. I’ll go down to 50mg then 25mg. No other drowsy pills seem to make me sleepy anymore. I didn’t realize how strong these pills are!

  • Peachy December 17, 2016, 8:23 pm

    I started taking this antipsychotic drug after a visit to hospital suffering with what I now know to be anxiety, stress and paranoia triggered by PMDD. After an hour talking with the doctor about my life I was given a prescription of 600ml XL, told I had psychosis and that I would need to take the medication for at least two years. When I first took this medication I felt as though I was strapped down to my bed unable to move or do anything this lasted a couple of days, I then developed an expressionless face, severe constipation and a increased appetite for carbohydrates which lead me to over eat and gain 100lbs in weight.

    Late last year my Psychiatrist reduced the med to 400mg and a few months after that to 300mg. I was starting to fell better and take control of my life… regular CBT therapy, started to exercise, eat healthier cut out meat and processed foods, lost my first 14lbs. Things were looking up. I was then allocated a new Psychiatrist.

    During a initial meeting with her I expressed that I didn’t believe I had Psychosis or Schizophrenia but actually believed I had something since my teens called PMDD (PreMenstrual Dysphoric Disorder) and that I want to slowly come off the medication to which she replied “well maybe you have Bipolar then.” This response triggered something in me and I knew it was time to come off the medication without her ‘help’. I made appointments with my GP (who is great) to get blood work, scans and see specialists regarding PMDD.

    Between May and November I reduced my medication twice by 100mg from 300-200 and then 200-100, giving my self a few months in between to readjust. I also started taking supplements to support my withdrawal. Magnesium, Ashwagandha, Iron, Macca root and epsom salts. I noticed a huge change in my personality from 300mg downward I felt extremely irritable and snappy. I’m a very creative person and I felt as though all my creativity had been zapped out of me, I felt numbed.

    Mentally I also noticed my thinking was confused, paranoid and hostile on the lower doses. After two years with this drug I decided enough was enough and I’ve have now been off the medication for 1 month after going cold turkey on 100mg.


    -The first week I experienced insomnia (wasn’t able to sleep for the first two nights then could sleep up to 5 hours), nausea, uncontrollable crying and a lack of appetite.
    -The second week I experienced limited sleep, nausea and itchy feet.
    -The third week I had increased anxiety, sensitivity to sound.
    -The fourth week I came down with a severe ‘cold’ had vomiting and diarrhea, nausea, increased thinking, sweating, and a headache every day. My sleep has increased however and I am now able to fall asleep when my body is tired.

    I cannot understand doctors handing out Quetiapine / Seroquel so easily especially to children or people with just sleeping issues. Thanks to everyone who has shared their story! Stay strong everyone! Love xx. “Tough times don’t last, tough people do”

  • Rebecca December 17, 2016, 9:50 am

    Please, please do not EVER take Seroquel! I was given a low dose for just insomnia. My GP thought it was a better choice than Ambien. 🤔 The horrible side-effects started immediately; racing heart, nightmares, sinusitis, rebound insomnia, tingling vibration in legs, depression and social anxiety disorder! I almost lost my mind. Now, after four months, I am having to SLOWLY withdraw. My doctor NEVER told me this drug was dangerous. It’s been a nightmare.

  • Cyn December 15, 2016, 4:57 am

    Two weeks off of Seroquel. The itching has been the worse part of the detox. I mentioned in an earlier post that I was going to find out from the doctor if taking Benadryl would only prolong this process of itching. Yes, it would prolong the process. Dang! When I have areas of intense itching I put some ice in a paper towel and place that on the area. That has been a saving grace.

    I have had some days of just feeling really tired and fatigued. The brain fog hasn’t completely lifted though I do feel like I have a bit more clarity with my thoughts. I can care enough to keep the thought in my head going. I am finding that I am suddenly remembering things I thought were long buried. I guess that means my brain is trying to work again! :-) Staying with it.

  • Cheyenne December 14, 2016, 4:46 am

    I am a 22 year old female. I have been taking 50 mg of Seroquel and 2 mg of Abilify for years. Recently, when I ran out of medicine, I went without it. It’s now been 1-2 weeks off both medicines and I have experienced strange symptoms. At night I have been extremely hyped up. I have started to see faces appear in my room as I look around. I am wide awake and am absolutely positive I am not dreaming.

    I also have bizarre thoughts and lie awake wondering why I am thinking them, all of which I can’t recall the content. The thoughts and faces keep me up the majority of the night. I also can’t lie still to fall asleep. I have a history of Obsessive-Compulsive Disorder and Attention-Deficit Hyperactivity Disorder.

    • Michelle December 15, 2016, 3:54 am

      Hey a Cheyenne, When you see these “faces” do they kind of look like wispy smoke-like faces that change? Or that you see shapes and things? I sometimes get that (usually if I’m VERY tired and have been fighting my normal bedtime). I brought it up with my doctor BC I was concerned and he said they were “illusions” and not to worry. Our brains do weird stuff.

  • Samuel December 13, 2016, 7:29 pm

    Today is my first day being off of Seroquel. It helped me when I slipped from a manic phase (that I’d been in for a few months) to a deep depression. The manic phase I think was precipitated by starting to smoke pot (daily) and going off my SSRI (paroxetine). My bipolar is a recent diagnosis; I know SSRIs can induce mania, but that drug really helped me (anxiety was my main problem before), even with the near complete loss of interest in sex.

    So now I’m switching from seroquel XR 200mg a day to lamotrigine. The main reason I decided to switch was because I slept way too much. I didn’t mind the haze as much because it helped the depression, even if it was still present. Anyways, my psychiatrist said going cold turkey was fine. Today is my first day.

    I’ve only been on seroquel like 4 months, but reading all of this I’m worried, but also glad to be going off seroquel after all the negativity of it for people on it long term. I guess we will see what happens. I’ll post again in a week with an update of how it’s going. I feel like life is an uphill climbing maze, searching for a peaceful flat plain. I wonder if I’ll ever get there. I want to hope again.

    • Cyn December 15, 2016, 4:37 am

      Never give up on the hope! I don’t know if being on it for a short time of 4 months will make it easier doing it cold turkey. If you find yourself and your body having a really hard time doing it cold turkey, maybe consider cutting it in half for a few days or a week and then keep cutting in half until you are weaned off. Do what works and is the most comfortable for you. Good luck!

  • Nicole December 10, 2016, 8:57 pm

    I was on Tegretol, Lithium and Seroquel since November of 2010. Doctor said I had bipolar depression. In March of 2016, I had a mental breakdown. So, I stopped taking the tegretol although my doctor argued that it was the lithium that was causing the issues. Even though all the side effects I was having was tegretol related.

    Months later I was still having problems and realized I needed to stop the lithium as well. I would throw up stomach acid on and off since on the lithium and it was only getting worse since stopping the tegretol. I told the doctor about it, but he didn’t seem to care. So, in September I stopped the lithium. The whole time I was on seroquel I wasn’t able to be awoken if there was an emergency and I had a hard time waking myself up to use the bathroom at night.

    The last couple months of taking the seroquel I had an irregular heart beat and was very dizzy. I told the doctor and he asked if I was getting 8 hours. I said yes and he asked what the problem was. I told him I was also having nightmares of people dying, but the doctor stated I don’t understand the problem when you are sleeping and that bipolar sometimes causes you to have those dreams.

    The last 3 nights I took the seroquel I had an irregular heartbeat and was very dizzy and ended up throwing up after taking it. So, I stopped it cold turkey. I started taking cod liver oil and a b-complex to help with the withdrawals and it seems to be helping. I have been sleeping better and am able to fall asleep on my own. I was told by another doctor that I have anxiety and depression not bipolar.

    I also realized that since off the medication I was taking it was making me act and think like someone that actually had bipolar. My mental health seems to be better and I feel like I can actually think straight. Plus, I found out by a different doctor that the seroquel, lithium and tegretol interacts with each other and this doctor was surprised that I was able to take them that long and was never in the hospital. And my therapist wondered why I was on both tegretol and lithium because she had other clients that was on one or the other not both.

    Yes, I had very bad withdrawals for about 5 days after stopping the seroquel. I was on 200mg at the time. I slept for crap and was throwing up throughout the day. And wasn’t able to eat. But after a week I was able to realize I can sleep and fall asleep without it. Yes, my anxiety level is bad somedays and I worry a lot when I am just laying in bed waiting to fall asleep. But learned that if I just focus on my deep breathing I can calm down and fall asleep.

  • Míssa December 8, 2016, 8:02 am

    Hey everyone, I’ve been on seroquel since 2013. I started at 300 mg every night. It was good for me for about 2 years but after that it just wasn’t working. I actually felt like it gave me more anxiety instead of helping it. Every time I’d take it I’d experience hearing and feeling my heart pumping in my head, adrenaline rushes, and just anxiety ridden nights falling asleep on it.

    Over that time I started to ween myself off. I am now taking whatever half of 25 mg is. However, this is my first night trying to be completely off of it. I’ve done this before at a higher dose of 125 mg and could go for like 3 days but the symptoms are horrible. I experience major insomnia, anxiety, uncontrollable shaking here and there, stomach problems, and headaches.

    So knowing this, I’m going to prepare for tomorrow by keeping Advil by my side, trying activated charcoal pills for nausea, and taking my CBD oil which is great for anxiety. You don’t need a medical card to by it either. When I get anxious I found pacing, deep breathing, putting heavy pressure on anxious parts of my body, exercising, positive thinking, and COLD air helps for me.

    Cold air makes me feel like I can breathe and for some reason makes me more comfortable. Sleeping on my stomach also helps because that’s where most of my anxiety is stored. I hope this helps in any way! I’m with you all! I hate this drug and can’t wait to be free from it!

    I hate being dependent on it because it’s so hard to get refills from the terrible, slow mental health system in this state. Waiting lists, unavailable psychiatrists, and all kinds of obstacles to keep up with it. I’m done being dependent! We can do it guys!

  • Jennifer December 8, 2016, 3:54 am

    Tapering is the way to go. I started at 400 mg for about 2 years. Went to 200 mg for 1 year. 100 mg for 1 year. 50 mg for 1 year. These first 4 years I wasn’t too anxious to get off of it, but I am sure someone could cut back much quicker than one pill size a year. I tried to go to 25 mg next but it was too big of a jump, and I had other stresses in my life at the time. I had strange thoughts and slight auditory hallucinations.

    Now I am taking a 25 mg pill plus half a 25 = About 37 mg. I’ve been doing this for a month and only slightly lethargic/irritable/anxious. I am going to go to 25 mg for another 2-3 months, then 13 mg for 2-3, then maybe down to zero. My advice to anyone is to taper.

    Just bite the bullet and take it until your body/brain can handle the next dose down. It will be better than being on it for life, having to go back on a higher dose, or (for me) ending up back in the hospital. Good luck everyone.

  • Michelle December 6, 2016, 5:50 am

    So I have to share a little background info first: I was diagnosed as bi polar when I was 22 (I’m 37 now). I refused to accept my diagnoses for many years and used drugs to cope and self-medicate (mostly cocaine). I’ve always experienced more depression than mania so that’s why coke was my drug of choice. I also had 3 very serious suicide attempts. When I was 30, I finally went to rehab and have been sober from drugs and alcohol since August 30, 2008.

    While in rehab I began to see a psychiatrist that I really bonded with. After I detoxed from the cocaine, my doctor started me on Lamictal as a mood stabilizer, Wellbutrin for the depression, klonopin (as needed for anxiety), ambien and seroquel to sleep. I have been a horrible insomniac my whole life. I believe we started with 300mg of the seroquel and through the years it went all the way up to 800mg at night before bed.

    In the past 5 years I have gained 65lbs and I have always been a very tall and thin person with a fast metabolism. I know it’s the seroquel that did this. I finally saw my doctor last week and told him I could no longer take the weight gain and other side effects so he agreed to slowly wean me off. He also switched me to Lunesta because I felt the ambien was no longer effective.

    This is the first week I’ve dropped down to 600mg at night with 3mg of klonopin (it helps my anxiety and racing thoughts at night), and the Lunesta. I’ve been sleeping ok. Nothing to write home about. I’m hoping I can decrease the dosage by 200mg every 2 weeks, give or take until I am completely off it. I feel like the drug helped in the beginning but now my body is just used to it and I’ve developed a high tolerance to it. 800mg is a lot!

    I can’t wait to be free of this. I don’t think it would be wise for me to go cold turkey. I once ran out for 3 days and ended up in the ER after not sleeping, a massive migraine, and horrible nausea. I had to get anti nausea meds and fluids so I’m wary of going down that route again. I just wish I’d never even taken this drug. Has anyone come off a high dose by tapering over time? How long did it take? Thanks all!

    • Jennifer December 8, 2016, 4:00 am

      With such a high dose, I would think it would be good to taper pretty slowly. To go from 800 mg to 0 mg should maybe take at least 2 years, maybe even 3 years. This is because you’ve been on it so long and at such a high dose. Patience, and you’ll be rid of it eventually.

  • Cyndi December 3, 2016, 5:10 pm

    I have been completely off of it for a few days now. I have been tapering down from 100 mgs for a month. I was put on Seroquel 8 yrs ago for major depression/anxiety. I was tried on every SSRI on the market and could not tolerate them. They made me feel like I wanted to jump out of my own skin along with major head aches and brain zaps.

    I guess you could say they worked opposite on me. That led to the doctor trying seroquel. At one point she had me up to 300 msg. That was way too much for my system. I was able to tolerate 100 to 125 mgs. I was having the long term effect of the not being able to retrieve my thoughts to verbalize them. I could see in my mind what I wanted to say, I just couldn’t bring that thought from my brain to speaking it.

    I would start to say something and not be able to follow through with the thought. It was terribly embarrassing. I knew I had to get off of the seroquel or continue down this path. I tapered down by 25 mgs each week until I reached 25mgs and then I stayed at the 25 mgs for three weeks. At the 25 mgs I was having some of the itching.

    Now, a couple days into being completely off of the seroquel the itching is pretty intense. I need to find out if taking Benadryl would help that or if the benadryl would only prolong the itching once I got off of the benadryl. I say that because I read somewhere that Seroquel has a histamine in it. Not sure how true that is yet.

    Since the tapering I have been experiencing less sleep, aching back and fatigue. I am determined to get through this. I thank all of you for sharing your stories. It gave me the courage to do the same. I anyone has found relief for the itch and aches, please pass that on. Good luck to you all with your journey.

  • Sand December 1, 2016, 2:29 pm

    My daughter went from 350 mg. to 50 she only experienced headaches and difficulties falling asleep. She’s now taking 10 mg of melatonin together with 500 mg Gaba as well as only 50 of the Seroquel. She will be going down in one more week to 25 and eventually she will be taken off this horrible medication. This medication gives my daughter hallucinations and sense of being lost as well as over eating habits and other ugly side effects.

    She’s now on almost 85% of natural supplements and a new healthy diet in combination with exercising 3 to 4 times per week. She has shown a great improvement on her mood swings and for the past 3 months, this is the first time she hasn’t gone on another cycle. I believe exercising together with a good diet as well as natural supplements have made a huge difference on her symptoms. Not only she looks better and feel better but me as her only caregiver can breathe easily for the first time in three months. (:

  • Th November 25, 2016, 12:36 pm

    Thanks to all of your for your informative words. I was on Seroquel xr 400 for almost two years. It was a life saver at first. Roll forward to today and i have gained fifty pounds and don’t remember anything even in same day of collecting task. I am thankful to have my children’s father that moved back in with me.

    So I decided to take the gene swab test and it came back that Seroquel is not a good drug for me. I changed and overlapped with Pristiq for about a week and half cutting down Seroquel to 200 but had major anxiety pop up and she took me completely off both Seroquel and Pristiq. She upped my latuda to 40 mg and I also take 100 lamictal in morning and 200 at night.

    Latuda is in evening also. I have been up earlier than ever in my life and when I sleep vivid dreams from past PTSD experiences along with soaking wet in bed. Anyone have any similar experiences? I also feel like I can’t breath laying down so sleep is hard.

    I’m determined to not go back to Seroquel xr but this is scary it’s been four days off and I’m concerned about going back to work in three days. I have a job that handles a lot of money daily and afraid I will just space out or argue with someone as I am very very testy. Thank you in advance for any help and replies. I’m thankful for this board as I almost checked into the ER two nights ago until I was able to find this information.

  • Alex November 24, 2016, 7:09 am

    Been off for almost 2 months now nausea has gone away and insomnia, but I’m tired all the time and I can’t concentrate at all. I see everything, but the connections are a lot harder to make. Plus my blood pressure has been higher than normal. I’m only 16 I have been on seroquel for 4 years, have changed, and I’m finally off, but this medication may have altered who I am and I don’t know if I will completely stabilize…

  • Chris November 20, 2016, 1:11 am

    I been on 300mg for 5yrs for anxiety and insomnia. Started Vekira Pak Chemo for Hep C 12 days ago and Dr said to just stop Seroquel… never mentioned any side effects!!!! I’ve been living in hell ever since. Resting heart rate of 104, can only walk about 10 steps and heart races again, extreme fatigue etc. So can’t work, can’t do chores, can’t make dinner… my life has come to a complete standstill. But I can sit and lie down and be ok. Finding this site was a true blessing for me as I didn’t know about withdrawal symptoms but it all makes sense now.

  • Reverend Galileo November 14, 2016, 2:48 pm

    Update: I stopped Seroquel in June. I had been on this drug for 15 years from doses of 50 mg to as much as 400 mg per day for briefer periods. I have complex PTSD. I used it for sleep and anxiety but have never been diagnosed with schizophrenia. So I am 5 months off of it and still have anxiety, heart palpitations, irritability, brain fog and cannot focus or concentrate.

    I’m glad I checked this thread out to remind myself it is mostly just prolonged post acute withdrawal. My doctor said it would take at least 6 months to start feeling better. It could take longer. Everyone is different. I am using a little Ativan for sleep and occasional morning anxiety and I hope that I will begin to feel better soon. I want to get off the Ativan but not ready at this point.

    I also have been keeping to myself as I find social contacts difficult. I have been quite depressed but not as bad as when I was on Effexor. I’ve tried all kinds of supplements and herbs but if they’re helping any I cannot tell. It’s difficult to eat, exercise or function at all. I feel restless and can’t stay focused and on task for long; in short, I can barely function. I’d like to come back here and say I am feeling much better in another month. We’ll see. Thanks for all who have written here, it does help!

  • Kris November 13, 2016, 2:47 pm

    Well, last night I didn’t sleep at all! I took 175mg of Seroquel and 12.5mg of Baclofen. I am feeling awful. Shaky inside, nervous, tingling arms and legs… I don’t know where to turn or what to do. This after only 9 weeks on these 2 awful drugs!!! Should I go to a hospital and asked to voluntarily commit myself to get help? Kris

    • Sand December 1, 2016, 2:44 pm

      Hey Kris, My daughter was put on Seroquel for bipolar disorder. She’s almost off this horrible medication but we did it slowly. And she changed her eating habits, incorporated exercise as well as some natural supplements and acupuncture. She sleeps between 8 to 10 hours every day but she has to follow a regime in order for her body and mind to understand what’s happening.

      We still working on getting her completely off both medications. She is on 50mg Seroquel and 600mg lithium. Look for other alternatives, I firmly believe that medication is not the answer to cure any disease – a total change in your life is the answer. Good luck to you.

  • Peter Müller November 5, 2016, 10:04 am

    Day 17: success, finally. I am now done with this rat poison, never ever again! What has helped me enormously (apart from massive doses of Omega 3) is the adding of a second AD (on top of 45 mg Mirtazapine): Maprotiline is the name to remember. It does wonders, especially for anxiety (which was my main issue during Seroquel withdrawal).

    If you are suffering from anxiety attacks, please mention Maprotiline to your doctor. This is probably my last entry here. I wish you all the best. Seroquel withdrawal can be done and is some much worth it, even if there are some difficult moment.

    • Th November 25, 2016, 1:31 pm

      Thanks so much for these posts. I’m on day 7 and feel horrible. Mornings are the worst. I’ve never been an early riser but up by five AM now. Nauseous, confused and paranoid. I see that it took approximately two weeks? I have to get this poison out of my system. I’m just hoping the latuda they gave me isn’t as bad. Thanks again for your posts.

  • Peter Müller November 3, 2016, 9:47 am

    Day 15 after Seroquel: unclear tendencies. The anxiety attacks, especially in the morning, do persist. Other than that, almost no W/D symptoms left.
    I think I am slowly getting there, but the uncertainty of how long I will have to suffer still is driving me crazy. I probably should not say this, but I found that a glass of wine (or two) in the evening are good for the appetite and also helping against the general malaise. Wish me luck.

  • Peter Müller October 31, 2016, 4:00 pm

    Day 12 after Seroquel: not a pretty picture. I had thought (hoped) this would be 100% done after a few days, but nope. Anxiety (especially in the morning) actually getting worse. Sometimes frightening dark thoughts, but they usually disappear relative quickly. The awful weather here (Berlin) does not help much, either.

    Smoking far too much and hoping this will be over soon. Appetite not great, but trying to eat at least something on a regular basis. Sleep is reasonably OK, but I might need some help tonight (after a few days without). Difficulty in concentrating – should prepare an exam in a few weeks from now, but struggling to get my act together.

    No nausea, no vomiting, no itching. It means a lot to me to share my experience with all co-sufferers out there. I am confident this will be over before the end of November. Will let you know.

  • Kris October 31, 2016, 12:03 am

    I was given Seroquel 200mg for sleep in rehab from Ativan I used for insomnia. I was told Seroquel was not addictive at all…they also gave me 20mg of Baclofen nightly with the Seroquel. I was on this for 6 weeks. After reading this and learning of the withdraw of both of these, I decided it was time to taper off. I went from 200mg to 150mg for 1 week and then to 125mg the next week, leaving the Baclofen at the 20mg for now.

    I am so nauseated and have a numbing affect in my face and hands..when I breathe in I have this strange cooling numbing affect in my nose, throat and even my stomach, which is really nauseous. I am thinking to hold at 100 for a couple weeks until the nausea subsides. In the meantime I will drop the Baclofen from 20 to 15mg. HOPING to go to 75mg of the Seroquel in a couple weeks and 10mg of Baclofen.

    I am furious that the rehab Dr’s put me on 2 meds that have horrendous side affects and withdraw symptoms, especially when I was there to get off Ativan that had been prescribed for insomnia for 2 years! Benzos for insomnia…should only have been prescribed for 2 to 4 weeks tops, not 2 and 1/2 yrs!!! All they did was switch me to 2 other drugs I now need to get off. THE withdraw of these are going to be harder than the Ativan!!!

    I am so upset!!! Not looking forward to the next drop at all after reading for hours the posts on this site…the nausea is awful now with stomach pains and the sleep is starting to be not very good…I am also a bit shaky. Will keep you updated.

  • Peter Müller October 29, 2016, 9:31 am

    Day 10 after Seroquel: Unfortunately, I am still experiencing mood swings and anxiety, especially in the early morning hours – most probably as a direct result of Seroquel withdrawal. Overall, this is manageable as I have now entered my second week without Seroquel (which makes me somehow proud), but I am nevertheless wondering when I will be back to normal – whatever that means.

  • Josh October 28, 2016, 10:55 pm

    (Male, 25 years old, 80kg, smoker). I’ve been taking seroquel XR 100mg for nearly three months, and today is day 3 of going cold turkey. My sleep has been highly disrupted, going from 9 solid hours a night to maybe 4 scattered hours throughout the same 9 hour timeframe.

    I’m determined to quit. I’m 100% sure the only reason I ever needed the stupid pink pills in the first place was to deal with my (now ex) partner and her abuse. Will keep this post updated as the turkey gets colder.

  • Riana October 27, 2016, 3:40 pm

    Hey all, so these comments have helped a lot the past few days. I’ve been on seroquel since 2004 and over the past 5 months have been being weaned off. Monday night was my last 50mg dose and I can honestly say that I didn’t sleep a wink Tuesday night. Wednesday started with extreme exhaustion, nausea, vomiting, diarrhea, shakes and itchiness like I’ve never felt before.

    Here I am, it’s now Thursday and I slept last night in two increments of about 4 hours each with a gap of 3 hours in between. I have found that taking two benadryl and a melatonin capsule knock me out for at least a few hours and relieve the itchiness. For the nausea I’m drinking ginger ale before my tiny meal, I say tiny because I can only get down a few spoonfuls before the nausea kicks in.

    I’m hoping the withdrawals don’t last too long, but I have found that sleep helps even though it’s the hardest piece of the puzzle to get right now. I wish you all luck in this journey to a cleaner form of caring for yourself and your illness. Be blessed!

  • Maryn Boess October 24, 2016, 4:37 am

    DO NOT GO COLD TURKEY. This is not a competition to see how tough you are. DO NOT GO COLD TURKEY. DON’T DON’T DON’T. I was a two-pack-a-day smoker and quit cold turkey. On Seroquel I was taking a measles 75 mg dose and decided I was tough and could quit cold turkey. It almost killed me. Insomnia, psychosis, agitation, suicidal impulses… Did I mention insomnia? I should have tapered, DO. NOT. QUIT. COLD. TURKEY.

    • Ashley October 29, 2016, 3:35 am

      I decided to quit taking seroquel cold turkey about 1.5 weeks ago. My dose was pretty small compared to others (only 75 mg) in the pm. The biggest withdrawal that I am having is insomnia. My body no longer knows how to sleep since I started this medication 16 years ago. Does anyone have any advice on natural ways to fall asleep while dealing with this and how long it will last?

      I don’t want more prescription drugs to deal with this, since the whole reason I quit was to rid my body of medications and I need to sleep without getting dependent on another drug. I was put on seroquel when I was 10, but now that I’m an adult these issues I had are no longer existent. Thank you to whoever can help and good luck to everyone who is going through this as well.

  • Phaedra October 23, 2016, 5:44 pm

    Hi everyone! I am so grateful for this thread. I am currently tapering and withdrawing from 25mg of Seroquel. This is the 3rd time I’ve done this (the first time was cold turkey and I almost scratched my scalp off). I was prescribed a low dosage to help with insomnia and anxiety after I relapsed on crystal meth 2 years ago.

    I find it does nothing for my sleep or anxiety. I am prescribed medicinal cannabis which gives me the results I need without the side effects of a pharmaceutical. I decided I wanted off this stuff after 2 years as I know the longer I am on it, the longer the withdrawal. I am actually very surprised at how hard this is hitting me. I cut my 25mg pills in half almost 2 weeks ago.

    I am tired all the time, in tears, nausea and vomiting, headaches and joint pain. Funny enough no anxiety and sleep is okay. To top it off I work in a stressful kitchen where I don’t eat enough and exercising hasn’t been a part of my life for a couple of months now (I am an avid runner) – so I am guessing because of my job and lifestyle currently that I am getting hit extra hard with my withdrawal symptoms. I hope they end soon. I am so glad I didn’t go cold turkey, even on this low dosage.

  • Peter Müller October 21, 2016, 3:46 pm

    I have not put any Seroquel into my body since yesterday morning (approximately 36 hours ago) and do not intend to ever do so again. Bottom line: Seroquel withdrawal is absolutely doable, I even went down from 25mg to zero as the last step. No further tapering (e.g. via 12,5 mg) was necessary.

    I have a clear head now (not imaginable with Seroquel) and I have also lost the awful metallic taste in my month. For all out there that are struggling, I wanted to give this to you as a message of hope. I have done it and you can do the same. It is so much worth the effort and pain.

  • Peter Müller October 20, 2016, 3:49 pm

    As a recap, I was @ 450 mg about 2 months ago and @ 150 mg about 2 weeks ago. Now @ 25 mg and feeling reasonably OK. On this basis, I will attack the final step tomorrow morning. No more SeroKill will be in my body as from tomorrow. Did NOT have any of the following when tapering down: vomiting, nausea, itching, insomnia.

    Had only regular mood swings, anxiety, reduced appetite, so more or less manageable W/D effects. I really hope that this toxic sh-t will be out of my system soon. To summarize, for short term users decreases of 50 mg weekly down to 100 mg and the 25 mg weekly below 100 mg are absolutely doable.

    Will confirm the success or failure in a few days from now.

  • Peter Müller October 17, 2016, 6:16 pm

    Have now reached 50 mg, going down to 37,5 mg the day after tomorrow. Surprisingly, I can still sleep more or less OK without additional medication (Melperon / Melneurin). Appetite somewhat reduced, but also OK. Would like to be @ zero SeroKill within the next 2 weeks.

    Major W/D effects are very frequent mood swings, anxiety attacks and a general feeling of insecurity, nothing else. No itches at all. I would like to be an example for others that SeroKill elimination is doable. Will let you know how it goes.

  • Michael October 17, 2016, 1:16 am

    It has been 3 weeks since my last dose… I am SOOOOOOOO angry with my doctors for not telling me about the withdrawal effects of this drug! 3 weeks, and last night I only got 2hrs sleep. I’m am so sleep deprived it physically hurts, drives me to panic attacks, hot and cold flushes, vomiting and join pain. God help me!

  • Peter Müller October 14, 2016, 4:28 pm

    I have been given at some point (luckily only for a few weeks) 450 mg Seroquel. As soon as I found out about the potential consequences (I had definitely already noted a massive weight gain, from 66kg to 75 kg in just a few weeks) I decided I wanted to get rid of this awful drug. Have tapered down in steps of 50 down to 150 mg without major issues, just a bit of anxiety and nervousness, plus diminished appetite.

    Since then, I have tapered down in 3 steps @ 25mg and I am now on 75. Sunday evening will bring the last 25 reduction to 50. From then on, I will go down in steps of 12,5 mg (more or less twice per week). I am a bit worried the closer I come to zero, obviously.

    If things work out my way, I should be at or very close to zero towards the end of this month. Wish me luck. By the way: I absolutely HATE Seroquel.

  • Jaishri October 11, 2016, 1:38 am

    I’ve been on and off Seroquel since 2010. When I am depressed and can’t sleep, it’s a wonderful medication because it will make me sleep (longer and deeper than a sleeping pill) and bring me to a functional level of depression. 300 mgs. has been the right amount for me. My bipolar cycles tend to be 3-4 months depressed, 3-4 months well (or manic or managing manic).

    Because the manic is not much of a problem for me at this time, I like to go off Seroquel when I feel better so my body can cleanse from it’s toxicity. If I notice signs of mania that I can’t manage, I can always take a seroquel because it works quickly to bring me back down to earth, but not necessarily need it on a regular basis. Anyhow, once I feel better I like to get off the drug ASAP albeit in a responsible, comfortable way.

    I drop 50 mgs. and allow slightly difficult sleep until sleep is easy. Once sleep is easy for 2 nights in a row I drop another 50 mgs. and on it goes until it’s out of my system.

  • Natalie October 5, 2016, 7:06 pm

    I’ve just gone cold turkey off 500mg per day. Have had 4 hours sleep. Not looking forward to this but I have to do it. The damage is not worth it. Good luck everyone.

  • Jessey October 1, 2016, 8:48 am

    I am down to 25mg but I am yet to taper off fully. Such is the ferocity of this drug. Every time I am trying I am getting bedridden. One can perhaps get off it if one quits one’s job and becomes institutionalized. That is not an easy option as you do not know in what state you are going to be even if you manage to quit.

  • Larry September 30, 2016, 3:20 am

    I was put on 1,200 mgs of seroquel and have bin on that dose for over 5 years, I have had a lapse in my insurance due to missing open-enrollment for my works insurance program. I was able to cut my dose in half after getting my last script in order to stretch them and that wasn’t the hard part. After that I moved too 300, cutting in half again, not so bad just a couple hours less sleep, motor functions fine, didn’t miss work. Now came the hard part, I ran out & am suffering like hell.

    My mental health has slightly changed and I get small ups and downs every once in awhile, and now after day 2, flu like symptoms. Just dry mouth constantly, and I don’t feel dehydrated what so ever, my mouth is just insanely dry 24 freaking seven. I am a big soda drinker for the caffeine due to the hours I work and I know that, plus working and moving constantly cannot be helping, cause we don’t get to drink on the floor where we operate heavy machinery.

    I’ve been reduced too 4 hours of sleep a night if I am lucky. I call my doctor and he tells me I need to get more ASAP cause it can cause manic episodes and depression, which I suffered with before, have had a past suicide attempt. And I keep giving myself anxiety attacks with overthinking everything, and the more research I do about the drug the more doomed and entrapped I feel.

    They need to enforce a new act for the doctor to review all of the long term affects, because I feel abused. What kills me is he knows I suffered depression, why would you give me something that could potentially end my life just because I am suffering from bad insomnia after the attempt. But my tip is too taper, if your on a high dose you may cut it in half till you get around 300-400 mg then I’d go down 50 mgs every week, then when you are down too 100 do 25 a week for 4 weeks. Good luck, going too bed, dry mouth is irritating me ATM.

  • WS September 28, 2016, 10:09 am

    I took Seroquel in low dose for 6 years for chronic insomnia (25-50 mg). I recently tapered off, and am experiencing headaches, bad dreams, anxiety and fatigue. I was just wondering how long it took any of you to finally have the withdrawal effects go away?

    • Jessey October 1, 2016, 10:13 am

      As per the drug websites it takes a minimum of 90 days to fully get off the drug. Then you have to deal with your routine problems as well.

    • Kathleen October 2, 2016, 4:25 pm

      In reply to your question, WS, only speaking for myself of course, because everyone’s withdrawals are different. I had to taper very very gradually because of the effects that even the slightest difference in dosage caused. I have been off completely now for over 3 weeks and am still feeling withdrawal symptoms. Waves of nausea, headaches, still have trouble getting to sleep as my brain adjusts. I have read that it can take up to 6 months to get back to a normal pre-seroquel life. Whatever that may have been. Good luck.

  • Meg September 26, 2016, 6:36 pm

    I was taking 150 mg the last year. I started while I was pregnant because it was a safe alternative. The dosage was low enough that my doc told me I wouldn’t have to taper, I’d be fine to just stop; she didn’t warn me about the withdrawal.

    The worst has been the vomiting, I can’t eat at all. It’s been three days since I stopped and I’ve already lost 5 pounds due to the excessive vomiting and nothing helps, not even the morning sickness “tips” that got me through the first trimester. Ugh!

  • JC September 22, 2016, 4:23 am

    I find all this information very interesting. I’ve been taking Seroquel for almost a year to help with the insomnia caused by Wellbutrin. I wasn’t able to sleep at all, and tried different things (Melatonin, Ambien, Marijuana and others) but none of them worked. It wasn’t until I got off the Wellbutrin and started taking 400mg a night that I could finally get a good night’s sleep.

    I also take it with Clonazepam. It’s a powerful combination but it’s the only thing that can get me to sleep. I have tried to get off the Clonazepam, but I get restless and can’t get to sleep. The only side effect I have felt is excessive daytime sleepiness, but it only happens when I’m not active during the morning. If I get myself out of the house and do some exercise, like walk the dog for half an hour, I don’t feel the sleepiness.

    I don’t know if it’s due to the fact I haven’t been taking it too long but I haven’t felt any of the side effects mentioned by others here. Hopefully I can get myself off it before I start feeling any of these side effects, but reading the withdrawal symptoms it seems like it would be harder on me if I stop. Thanks for sharing all your experiences, I will take them into account in the future.

  • Heidi September 19, 2016, 9:10 am

    Reading these messages is very scary. I’m only on a 25mg pill for sleep, but I didn’t know about the weight gain and the point of it was to get sleep so I could lose weight, so I’m going to get off of it. I guess my doctor wasn’t too swift prescribing it for sleep since my goal was weight loss, huh?

    Amazing how many times I’ve noticed that doctors don’t know what they’re doing. I’m thinking to abandon medicine totally. Maybe become a breatharian… joking, but at this point, it seems equally reasonable.

    I wanted to chime in about something though. Withdrawal of anything is always similar. The reason is because of the adrenaline. Cold turkey will push your adrenals into overdrive and you will be in permanent fight or flight. When your body starts running out of materials to make adrenaline (adrenal fatigue), you get the symptoms of exhaustion with insomnia, body aches and flu symptoms.

    Your body is trying to re-up the neurotransmitters, and the first step is adrenaline, which releases histamine and the histamine stimulates neurotransmitter production. That’s why you’re itching, that’s why you’re anxious, etc. There are websites out there that talk about this, and talk about using Benadryl to counteract part of the effects.

    Additionally, Seroquel like most antipsychotics of both typical and atypical types, is an antihistamine. So you’re getting a double dose of histamine reactivity. Antihistamines are almost all anticholinergics, so bingo, brain fog, especially for elderly dementia. Doctors in rehab have drugs that target the excess adrenaline, and some prostate enlargement drugs also target and deactivate adrenaline.

    That’s the real source of the problem, the adrenaline. But OTC, our choices are limited to mostly antihistamines. However, all antihistamines will make you gain weight also. They have the same effect on your thyroid as antipsychotics. So once you’re off of the Seroquel, you also need to get off of the antihistamines.

    If you’re ever taking care of an elderly person, NEVER give them an antihistamine. You will see a visible degradation of mental ability. To a much smaller extent this also happens to younger people. Abandon the antihistamines as soon as you’re over your withdrawal.

    If you want to verify any of this, go to pubmed and put in some of the vocab words in here. Also, google something like “home rehab” or “rehab at home” to verify the Benadryl stuff I said. The info is out there, but it took me months to find it, read it, understand it. Have patience and read up.

    Pray for me because I’m quitting it, but I’m going to taper even the 25mg, while taking Benadryl. I’ve had good results getting off Cymbalta that way. I also took an anti-nausea, Dramamine when I got off Cymbalta. The combination of the two helped a lot. Especially with sweating. If you can get ondansetron, that will really really help with the sweating.

    It’s not controlled so you can ask for it just because you’re nauseous. Never believe a doctor if they say you can just go cold turkey. It’s a cruel thing, because they’re betting you will fail and run back to him. Quit safely, with understanding of what’s happening.

    I have something else to add. Seroquel is a neurotransmitter ANTAGONIST (look it up, compare with agonist and modulator), that means, your body will make tons and tons and tons of extra receptors in a vain effort to have them activated. So when you take it away, your body suddenly senses the deficit in neurotransmitters and wham, nasty withdrawal. This is the opposite of opiate withdrawal.

    Take opiates for a long enough time and your body decreases the number of neurotransmitters. If you go off of them, you are still in a deficit, but the deficit is now because there aren’t enough receptors, so it seems like there isn’t enough neurotransmitter activity. Also your body stops making dopamine if you’re on an opiate on a high dose for a while.

    Oddly, the solution to Seroquel withdrawal is an opiate to replace the dopamine that is missing, or something like Cymbalta which increases all 3 of the most studied neurotransmitters (serotonin, norepinephrine, dopamine). Taking Cymbalta would be the fastest way to balance your body out again. But this concept has not yet percolated from the science lab to the doctor’s office. You can verify what I’ve said on pubmed, but pubmed doesn’t make the rules for medical practice.

    This gap between science and medical practice is what’s hurting all of us. The people responsible for slowing this process down (from sci to med), are the Public Health Policy makers. Many of them are drug company execs. They don’t want to cure you, but keep you addicted. Just like drug dealers, only legal.

  • Simon Westwood September 12, 2016, 3:54 pm

    I was put on this drug two months ago and started on a low dose of a quarter of a 25mg tablet per day till I felt happy to try a full one. I’ve felt worse and worse the more I was on it till I decided to come of it. Ive been tapering down back to a quarter of a tablet and yesterday I didn’t have any. Today I can’t stop having panic attacks, sweating and terrible chest pains. This morning I felt suicidal and ended up taking valium which freaked me out rather than calming me down like it normally does. Its the anxiety and negative thoughts that are doing me in. I may take a very small dose tonight.

  • Anne Marie Silbiger September 11, 2016, 6:11 am

    I don’t see dates for comments but it’s September 2016 as I type this. I’m trying to come off 75mg of Seroquel. It helped initially last year in October with severe anxiety, sleeplessness and suicidal thoughts. I ended up in hospital and the doctor there prescribed it.

    Now a year on I feel like a woolly headed fool as most days I struggle to remember words or wake up out of the drowsy state it has me in. Worse are the night terrors, sleep paralysis I think is what I get. I dread sleep. 4 days ago I stopped and I’ve not been too bad apart from nausea and excessive sweating.

    I’m of course nervous of any symptoms returning so I will go back to the doctor if this happens BUT I refuse to take this medicine anymore. Good luck to all suffering with the withdrawal symptoms. I have been there with seroxat and back then they didn’t believe me until it broke on the news.

    • Kathleen September 14, 2016, 9:21 pm

      In reply to your comment Anne Marie, yes, there are dates next to comments going back as far as 2014. They’re not very noticeable, but they are there. But the side effects of withdrawal are listed at the very top of this forum, in case you didn’t see that part. I just re-read it and still cannot believe, how horrific and toxic this drug is.

      I’ve been tapering off for months now, from 100 mg down to the slightest little smidgen that I can slice off and still be able to swallow. Last week I tried not taking it anymore, even with the tiniest little piece of the pill and I was awake for well over 36 hrs. I decided to take it twice the next day to get my brain back to normal and could not believe how horrible it affected me after tapering down to almost nothing.

      So there it is… the toxicity even at the most minutest amount is still too much to handle. My side effects are always the same, flushed, nauseated and headachy. Everyone here seem stop react differently. Good luck but keep at it. I feel so much better being almost completely off, can’t wait till I am done with it. -Kathleen

  • Ryan September 10, 2016, 3:37 pm

    I was on 700mg for approx 10 years (as well as escitalopram), only in the last two I researched into the long term effects of staying on it, and was quite alarmed by what I found so decided to quit, but not before reading forums like these so I knew it wouldn’t be easy, and it wasn’t. Exaggerated mood swings, from optimism to suicidal in a matter of hours, very bad stomach pain for months, aching all over at times, and a lot of lesser ones. I live in UK and am thankful we have a free but overworked healthcare system, and throughout my consultations I was seen by different people who asked me what I was taking and how I was feeling, but never asked me how long I was on it for.

    10 years is far too long and the seroquel (called ‘baby heroin’ in some countries) turned me into a lethargic zombie. I feel I was ill-advised into the long term effects of this drug but know I was initially put on it with the best of intentions from my counsellor and psychiatrist. In short my personal advice is to get off it as soon as you can, expect a lot of emotional and physical discomfort (hopefully you will have neither), but it IS WORTH IT in the end.

  • Jaco September 9, 2016, 6:20 am

    I’ve been iff seroquel for 7 months. Was on it 7 years in a row ar about 200 mg a day. I tapered down and the withdrawal was pretty bad mostly horrible itching and insomnia. Still have the insomnia. Maybe sleep 5 hours a night which sucks. I think I am noticeably aging because of lack of sleep. I have lost 20 pounds without even trying which is great. I’m just super happy to be off of that sh-tty drug. I took a lot of vitamins and amino acids which really helped. It can be done. Good luck.

  • Jennifer September 7, 2016, 9:46 pm

    I have been off seroquel for a couple days now due to running out and I feel like total crap. Glad I read all this cause now I know it’s the seroquel doing it… Ugh.

  • Elisabeth September 5, 2016, 3:09 pm

    I’m bi-polar and ADD with severe mood swings. After my second pregnancy I got really bad and almost ruined my marriage. When I stopped breastfeeding I decided to do something about it. I talked to a psychiatrist and went through a few different medications to find one that worked and had the least amount of presented side effects.

    I started taking 12.5 mg in the morning and ended up going to 12.5 in the morning and 25mg at night. It worked for a little while but then I noticed the severe mood swings, irrational thoughts, weight gain (despite exercise and diet), and the fact once again my marriage was being horrible affected. 2 days ago I said enough was enough and I’ve quit cold turkey.

    I can’t sleep well at night, am nauseous from the time I wake up until I go to bed, I can’t focus for more than 5 minutes, and I can’t remember anything reliable. This will change and lessen over time but sucks. Thanks seroquel.

  • Slow&steady August 25, 2016, 2:45 am

    I have had bad experiences with drug withdrawal, enough to not want to live anymore. I have finished taking seroquel a week ago. I am only experiencing mild symptoms. The secret – reduce by only 10 percent or as close to this as possible every two weeks or longer if necessary. It’s hard to be patient but u can do it. Also Google Biobalance a new and very successful nutrient treatment. I pray this will help someone.

  • Patti August 23, 2016, 1:08 pm

    6 weeks ago I cold turkeyed depakote and lamictal combined. I had been on them for over 10 years, misdiagnosed bi-polar. It was rough but within a month I was starting to think. 2 weeks ago I started with the seroquel which was originally prescribed to help with sleep. I have been on 200 mg for 10 years. Coming off this drug is worse than opiate withdrawal.

    I am having to taper. I have found exercise is the key. I am walking at least 2 miles a day. The walking helps with the pain, had to power through pain at first. The not being able to think is the worst of it. I am in constant fog and I still have another 100mg’s to go. This drug should be banned. What is helping me the most is not fighting the emotions coming back, it’s just my brain waking up they are going to be exaggerated after so many years of being asleep, exercise and believe it or not beer.

    Hope this helps. Those of you who are working and doing this I am in awe! I also tell myself at the worst times that which doesn’t kill you makes you stronger!

  • Jennifer August 22, 2016, 2:46 pm

    Omg, they put me on that Seroquel to help me sleep in 2005. I was on 1600mg. I was to take it at night. I couldn’t walk. I had to crawl to the bed. Then they went down to 1200mg. Same thing happened. Then 800mg. It made me so tired in the day. Then I decided to take 1 400mg pill and a half and then I could sleep and I felt better.

    Now it doesn’t work at all. I have gotten me a new medical doctor and I was told I should have never been on that stuff. The with draws are terrible. I can’t sleep any at all, sweating, shaking, vomiting. I have been to the doctor and ER a total of 5 times in 13 days. I’m going back to the doctor again to day for them to see how I’m doing. I have been reading a lot about that Seroquel and that stuff is dangerous.

    If you have been taking it for years, it’s going to take months and months for you to feel better possibly up to a year. They put me on this mess to sleep. I am not bipolar or schizophrenia and it is used for that. When I get well, I’m thinking very seriously of suing the doctor that put me on this. For the ones that are trying to get off of this and has been on it a long time… be ready because you are in for some sh-t.

    • aka aka August 27, 2016, 7:34 am

      I was on 1,200 and now since October 2015 and now is August 2016 I went from 1,200 from a horrible doctor to now 150 mg. It is now weird and hard. People will never understand. I am still trying to go to 150 mg’s. I hope you do well.

  • keterpele August 19, 2016, 7:34 pm

    I took seroquel xr 200mg for about 2.5 year. I tried to stop taking it once in a while for a year. After half a day w/o seroquel I always felt like as if I have a flu and I felt like I had to grit my teeth all the time. Of course sleep would never come and I’d take the seroquel before completing the day. I was also using 20 mg paxil to go with it but paxil was quite easy to quit.

    I didn’t even get through anything. I guess it was just like placebo comparing to seroquel. So, after a few attempts I finally didn’t feel the flu-like symptom. Of course the sleep was not there again but it wasn’t the biggest problem. I started to fall asleep usually around 6-7 in the morning. The days past like this.

    And here come the ‘itching’… unbearable itching. I often hurt myself cuz of it. It made me quite paranoid that I had some other disease. It didn’t go away for 4-5 months but it wasn’t that severe after 2 months already. I must say that I don’t miss seroquel at all. Wish you all the best.

  • Jas August 19, 2016, 4:56 pm

    I have been going through withdrawals for 9 weeks now. I wasn’t sleeping more than 2 hours a night until I got some melatonin slow release. Nausea, dizziness, depression, lethargy, unfocused, extreme anxiety as well. Mind you, my psychiatrist didn’t feel the need to warn me about withdrawing or help when I complained of acute insomnia etc. he actually sat there, scratched his chin and stated “I just can’t work out why your insomnia is this bad”.

    I had to find out for myself and my pharmacist helped with the melatonin. I thought I was relapsing in my mental health not understanding withdrawal symptoms. I simply can not believe that bloody doctor did not consider withdrawals or even attempt a discussion with me about it. Seroquel is highly toxic and I regret the day I ever began ingesting them (ironically for insomnia).

    I should have been told to take a bloody long holiday, instead I got a prescription. I took them for two years. I would have benefitted more from a 2 year long holiday – God knows it would have cost the same and I wouldn’t be in this sh-tty withdrawal not knowing if I’m ever going to be able to sleep a natural unaided sleep again in my life.

  • Michelle August 18, 2016, 7:03 pm

    My former psych prescribed first Latuda and then Seroquel as an adjunct to my antidepressant. I don’t think either drug did much in this regard, but Seroquel has at least helped me to sleep. When I expressed a desire to taper off my medication, my doc told me I was on such a low dose of Latuda (20 mg) that I could just stop taking it. That’s when all hell broke loose, I was hospitalized, and it took well over six months for me to feel any semblance of “normal.”

    She started me on Seroquel XR in December and got me up to 150 mg, but since March (and with a new, much more proficient psych), I’ve been slowly tapering off Seroquel. Currently, I’m at 75/75/50 (lower dose on every 3rd day), and I already feel mild to moderate W/D symptoms (nausea, dizziness, agitation, “Rorschach brain,” etc.). I almost feel that I need to see a neurologist in case this med is causing long-term damage.

    What helps me with my W/D symptoms are frequent, rigorous cardio exercise (45 minutes to an hour a day), along with frequent productive activity. Work has been a Godsend in that it keeps me busy and keeps my mind off my W/D symptoms. I am really worried about how my body and brain are going to handle being completely off this medicine, but under my doctor’s advice, I’m tapering off very slowly–glacially, in fact.

    It may be another year before I’m off this med completely, but I’d rather go slow and steady rather than rush myself off and suffer horrible W/Ds like the ones I had with Latuda.

  • Shona August 16, 2016, 7:00 am

    I was on a low dose of Seroquel for the treatment of insomnia and PTSD for about two years when I suddenly stopped taking it. I experienced a brief manic and psychotic episode where I was hospitalized for a month and diagnosed with schizophrenia and put on much higher dose of antipsychotic for two years. I did tell the psychiatrists I had suddenly stopped taking Seroquel and I thought that was the reason for my admission but they disbelieved me.

    The Seroquel reduced my level of cognitive functioning and motivation so profoundly I stopped showering every day, I was unable to remember my telephone number and when I was put on the anti psychotics for schizophrenia my cognition and motivation worsened significantly. So very badly that I was diagnosed with the negative symptoms of schizophrenia and put in hospital for my low motivation symptoms, they thought I had major depression and wanted to try Lithium and ECT with me.

    As if I wasn’t already traumatized. I was offered no psychology for the PTSD but I was so medicated with anti psychotics that it didn’t matter. I wasn’t able to participate meaningfully in psychotherapy anyway. It took two years before the doctor would reduce my anti psychotic medication down to nothing, so I could prove once and for all I wasn’t schizophrenic.

    But I’ve now been off anti psychotics for over a year and feel fabulous, I’m even getting my mojo back and I’m going to engage with psychotherapy to get on top of my PTSD, for once. So it all worked out in the end but I wouldn’t recommend taking antipsychotics for an illness that does not have psychotic features. I think I was badly let down.

  • Gemma August 14, 2016, 9:32 pm

    I can honestly say, since being prescribed Quetiapine, it has absolutely ruined my life. To anyone thinking or about to start this medication, I urge you to do as much research as possible because the withdrawal effects from however little dose/time you’ve taken it, is horrific. My medication journey hasn’t been an easy one. I was originally prescribed most antidepressants which failed to work.

    After several months off work, no social life, erratic mood swings, I was beyond desperate to get better and be “normal” again. I was then prescribed Quetiapine by the Psychiatrist. Initially, I felt better. I was sleeping better and my mood swings became less erratic, my friends and family could really see a change in me. Within weeks, things took another turn.

    I became to feel like a zombie, I couldn’t function without having a least 15 hours sleep, my weight gain was beyond shocking and my mood swings were worse than they’d ever been. After three months of hell, I decided the best thing to do was to stop Quetiapine altogether under the watchful eye of my Psychiatrist. I’m currently on day 4 and it’s probably the most unwell I’ve ever felt in my life. Constant nausea, vomiting, migraines, these crippling electrical volts going through my brain, and continuous low mood and suicidal ideation.

    It’s not been easy and I can only hope I get through this. If you’re reading this with the intention to start Quetiapine, I urge you to reconsider. I understand different people respond well to different medication, but it seems I won’t be the last person writing in this forum (amongst others) with similar experiences.

  • Norma August 11, 2016, 9:52 am

    I’ve been off of 600mg Seroquel for three months now and still have severe anxiety, dizziness, burning sensation in my head, insomnia, and involuntary muscle movements. I’m thinking about coming off Celexa now, but I’m wondering if it is too soon.

    • Michelle August 18, 2016, 7:07 pm

      Hey Norma, You might want to give your brain a longer break before tapering off anything else. Talk with your doctor about it, but with all of the W/D symptoms you’re still having after 3 months, you might want to refrain from tapering off anything else until your current symptoms start to stabilize. JMHO, but check with your doctor before doing anything.

  • Jeremy August 10, 2016, 12:22 pm

    Just started, been wanting to quit this freakin seroquel. More like nyquil. Starting cold-turkey today and especially after reading these posts. I have been on it for 2 years and was having the worst chest pains for 33 and I am healthy. What worked to stop those pains was lowering the dosage.

    The quacks like to up your dose to shut up your crying and keep you sedated. This proved to be extremely unhealthy and increased my panic attacks which is the most creepiest feeling ever by the way. Worst comments on this drug I ever seen too, glad I read this. Feel like a bubble head, I plan like the other girl getting my life and brain back and fire doctors that do not care about you.

    This is walking the plank here in my view by taking this crap. Yes, hard to hold an intelligent convo with dull insensitive emotions. I am actually a Christian, but this makes me so angry. Also I think it has affected my spirit negatively which is not good. It feels like I’m a zombie on Walking Dead show, fell victim to another quack.

    No sense in complaining and crying no more, on one thing to do now is to try to get my senses back the healthiest way I can.

  • Kathleen Hamilton August 9, 2016, 3:24 pm

    So glad I found this forum. I’ve spent 9 months tapering off 300 mg of Seroquel for sleep (on for 2 years). Quit completely a week ago and it’s been hell. All the symptoms you all have talked about, nausea, worsening insomnia, itching, joint pain, hopelessness, etc… Yet I am so glad I quit and I am bound and determined not to go back. Tired of using prescribed pills to avoid facing my issues. It’s going to be rough, I have no illusions about that, but I feel freedom right around the corner. Thanks so much for you all sharing your experiences – I don’t feel alone or crazy anymore.

  • Ileene August 8, 2016, 10:21 pm

    I have been on Buspar for 7 months now. After having been on that for only a couple of weeks, I realized my anxiety had not be under control yet. I wasn’t sleeping through the night; mainly waking very early. After having a panic attack, the ER doctor put me on Prozac to accompany the BuSpar.

    The Prozac made me so ill in three weeks that I could barely eat due to the nausea and I was almost nonfunctioning. I did sleep, however. My primary doctor took me off of the Prozac and prescribed 25 mg of Seroquel. I was sleeping like a baby! That along with the BuSpar seemed to be working together. After about a month, I started to notice how hungry I had become.

    After about two months, I was having terrible hypoglycemic symptoms and what I thought was increased heart rate. My doctor was monitoring everything and I had to monitor my glucose levels. Meals wouldn’t last long. The symptoms would come on quickly once they started and I would get fast and hard headaches and then started to shake.

    I had to plan my day around what and when I would eat and be sure I was either near a restaurant or equipped with decent food items. My doctor was reluctant to take me off of the Seroquel because I was at least “balanced” and sleeping. After another month, I had had it with being run by food. I saw a PA who told me I could cut my dosage (I am very sensitive to meds anyway) but to do it gradually.

    I’ve been cutting the 25-mg tabs in half for almost two weeks now and have been more anxious. Two days after on the lower dosage, all at once my heart rate increased and I started to tremble and couldn’t stop. I had to go home from work. A week later, it happened again but to a much lesser degree. I’m sleeping almost as well as being on the 25 mg full dose but not quite.

    My hands shake more and I become more irritable. I have noticed, though, that I don’t get as hungry as often but I still have to be on top of having snacks. I’m hoping to quarter the tabs within the next week or so. Not sure how long I should do the tapering. Has anyone else had hypoglycemic symptoms on this med??

  • Ana August 6, 2016, 11:00 pm

    I was put on Seroquel while in treatment – for sleep and post-acute withdrawal syndrome from suddenly stopping benzos. I was on 250mg a day. I wanted to quit, but had read the difficulty many had had. I started it in October and decided to quit in February. I tapered down successfully, but it took me almost 6 months to do it. Here’s how I did it:

    Because I was on it only 4 months, I was able to reduce 25 mg a week until down to about 150 mg. Then it got harder. I had to reduce by 12.5 mg about every 10-14 days. By the last few rounds until quitting, I went from 37.5 mg to 25, to 125, then to ~ 6 mg, then to 3. I am finally off, as of three days ago.

    The way I would know it was okay to further reduce was by how anxious I wasn’t for two days in a row. The anxiety was horrible but it would lessen with each lowered dose after some time. I did research on anxiety and found three things that helped make this journey more bearable. I found Acetyl L-Carnitine (ALCAR), Niacinimide, Holy Basil, Turmeric, and L-Tyrosine.

    The upside is that not only was my anxiety improved, but I got a mood boost from the ALCAR. My thinking was clearer because of the L-Tyrosine, as well. I’m still not sleeping well. That started at 12.5 mg. I do use Deep Sleep (herbal) and Melatonin with L-Theanine. It helped tremendously along the way, now not so much. But this is a powerful drug that is helpful until the side effects outweigh the benefits.

    For me, it resulted in about 20 pounds and feeling drugged much of the time. I feel like a better, happier, and fatter (lol) version of myself. Hopefully not for long on the fatter part! I wish everyone success! If you’re thinking of doing this cold turkey, you are making a big mistake. Of course you want to be off of it right now. But our brains cannot handle it, and it may put you in the ER.

    If nothing else, tapering will help with learning patience – it did me – and it will minimize (but stretch out) withdrawal symptoms over time. I can handle being a little off part of the time much better than completely wrecked for a long period of time. Hopefully my experience will help someone. :-)

  • Craig August 6, 2016, 6:07 am

    I was prescribed this hellish drug the 1st time I went to rehab (for a heavy hydrocodone addiction…which after 18yrs, I’ve finally overcome). Seroquel was great for sleep @ 1st, was prescribed 200mg/nighttime. But like any drug for me, if it gave me any type of mind-altering effect, I would increase dosage. Over the next 5 yrs I had moved my way up to 1500-1800mg(5-6x300mg) a night & would fight the sleep to feel the awful buzz this drug gave me. I don’t know why, I am an addict is all I can tell you.

    It eventually lead to me becoming the biggest a-hole you ever met, not to mention i puffed up & gained 25 lbs cuz it gave me the munchies. I was literally a fat Oscar the Grouch 24/7 & for some reason, my girlfriend stuck with me(Now thats true love…or just plain sad, but I love her for it either way). Years passed & Finally, I grew to hate it. If this is what it took to sleep…then I was willing to never sleep again.

    So I packed a suitcase & rented a room for 2 wks at an extended stay motel & quit cold turkey(no visitors except for my girlfriend to bring me food & see I was alive then leave). It was hell… I didn’t sleep 6 days in a row, just tossed & turned for what seemed an eternity. I sweat, had pounding migraines, racing thoughts, horrible anxiety… I couldn’t even watch TV it was so uncomfortable.

    It was like opiate withdrawal all over again. I couldn’t eat & had to force myself to drink a 32oz gatorade everyday. I wanted so badly to say “screw it” & go find some valium or ativan but I toughed it out. After 2 wks I went home & still was only getting maybe 2 hrs of sleep in 30 min intervals a night but it slowly got better. It took MONTHS before I was able to get a solid 4-6 hrs of sleep again.

    I don’t wish that on anyone. I never thought the day would come when I didn’t need an ambien, ambien xr, lunesta, remeron, seroquel, ser xr, etc. just to get an hr of sleep. My advice, don’t even give the doctor(thats bribed by the pharm company to push its pill) the satisfaction. Try all other avenues 1st, whether it be herbal or better yet, try one of those relaxation drinks (Drank, Purple Stuff, Sippin Syrup) they all have those herbs that help with sleep such as valerian root, rose hips, L-theanine, melatonin, etc…

    I don’t know if what I just typed will actually help anybody, just sharing my experience. Good luck all!

  • Tunisia August 5, 2016, 9:21 pm

    I quit cold turkey on the 3rd from 300 mg Seroquel XR daily. I dunno if any of you have encountered this, but it gives me terrible panic attacks. I wound up in the hospital on the 3rd with a massive panic attack, and that’s what prompted the quit. So far I feel like hell. I’m sleeping, but probably only because I’m taking Ativan. I have no appetite, weakness, fatigue, and brain fog.

    I’m doing better than most of you guys by the sound of it, but I don’t really get why ’cause I’ve been taking Seroquel at a reasonably high dose for almost 2 years. Oh, and I’ve quit smoking at the same time. Jooooy~

    Anyways good luck all of you. If anyone wants to be Seroquel quit buddies and we could help each other along with moral support and someone to complain to who understands I’d be up for it; feel free to email me.

    • Charles ( UK ) August 6, 2016, 9:18 pm

      Hi there Tunisia, That sounds quite a lot to cope with in one go, were you smoking for some years? You mention panic attacks and it got me interested.
      I had a few panic attacks when I was on quetiapine and two of them were bad enough for me to be sent to hospital in an ambulance, the other occasion the ambulance men stayed with me for an hour or more in my home. Have you spoken to a doctor/psychiatrist about a systematic, tapered withdrawal for the nicotine AND the quetiapine, maybe to put some structure around it all?

      I was never in a high dosage, I did try 200mg once and it floored me, I promised myself I would never do it again, I took a 100mg for three years. After dropping by 25mg a week I stopped nearly a month ago with very little to worry about regards withdrawal symptoms, I was lucky because I had nothing else that conflicted with it having detoxed from painkillers a couple of months before.

      Whatever you do I really wish you well, the symptoms seem so different for so many people there doesn’t seem to be anything consistent, at worst all the symptoms you have and at best, some flu like feelings, some hot flushes and sneezing? All the best to you, Charles

  • Ari August 3, 2016, 1:48 am

    I’m in the process of quitting seroquel / quetiapine after over 15 years of taking between 50 and 12.5mg. I saw a lot of terrible stories/advice in the comments. Do not quit cold turkey. Be extremely skeptical if a doctor advises you to. Even if you haven’t been taking it for awhile, be cautious and work alongside a medical professional to taper your meds gradually. I’m at 6.25mg now and even that slight decrease is powerful. You’re taking this for a reason, so be kind to your brain and let it gradually adapt as you quit. You will get there. Good luck!

    • Ted August 4, 2016, 5:00 pm

      Ari, I totally agree with you. I dropped 100 mg of Seroquel from 200 mg and dropped 0.5 of Klonopin from 1.0 all in one month. I am now trying to figure out how to regain more mood stability while still trying to not go back up any. It was too much of a drop in Seroquel at one time, and I shouldn’t have tried to also decrease another med at the same time.

      What I really want to do is to figure out how to heal the root of what is causing my symptoms and to stop just treating the symptoms with medicine, but to stay on medicine until I have gotten enough true healing of the root causes so that the withdrwal from a safe taper is not a big deal. Best of luck. – Ted

  • Tilly August 1, 2016, 12:30 pm

    I am 23 and was put on 50mg over a year ago as I lost the plot a bit at Uni and started hearing voices. Finished Uni (yay Masters) and am a lot happier now so am trying to wean off. All I’ve done is drop from 50 to 25 and oh my goodness I feel horrid.

    Vomiting, nausea, headaches, eye pain, dizziness, tiredness, sound sensitivity, it’s awful! I have honestly never been this physically ill in my life… I hope it gets better soon. :(

  • John August 1, 2016, 3:51 am

    My dance with Seroquel has gone one for many, many years. On it, off it, on it, and so on. Off it due to cost, no alternatives left. Got up to 600 mg and it’s taken me a year to get down to 150mg. Went cold turkey two days ago, withdrawal is far worse than I expected.

    Nothing close to benzodiazepine withdrawal, but still very unexpected. Cold sweats, flu like symptoms (runny nose, nasal issues, headache), insomnia, feels like I am in a dream during the day, nightmares at night (if I do sleep). Average sleep per night is maybe 4 hours but very broken.

    Woke up at 3am and couldn’t go back to sleep. Had these side effects before and are no less comfortable now. If you are coming off Seroquel read this thread it will help you understand what you are in for. It definitely helped me. Good luck!

  • deris July 30, 2016, 6:34 pm

    Hi everyone, just an update, I have been off of this dreadful drug for three months now after tapering off, (I think as we all react differently, it is really trial and error). Anyhow, I feel so much better, getting to sleep is still an issue but once asleep I do sleep well. I have been doing a meditation called a body scan (https://www.youtube.com/watch?feature=player_embedded&v=zsCVqFr6j1g) and it works really well, it slows your breathing and occupies your mind.

    Even though I have had different issues to cope from the ones that led the doctors to put me on this drug I am doing well and have even secured a new job. The things I would recommend are be prepared for all the stuff the withdrawal throws at you. Also exercise, I walk every day and it has helped so much. Also I do still feel anxious, sweaty and as if my heart is racing but I use belly button breathing techniques.

    I’m not saying life is perfect but it’s much better for me not to be on this drug, I can engage and have all round totally better cognitive function.
    I just wanted to give light at the end of the tunnel. But please do-not beat yourself up if you are struggling or feel you need to take this drug we are all unique and now may not be the right time for you. Please look after yourselves and be kind to yourselves. Wishing everyone kindness.

  • Kathleen July 27, 2016, 3:41 pm

    Its been three weeks since I tapered down to 50mg, and that did not present any side effects; however, after trying to split that in half to make 25 mg, they started. Severe nausea and headaches. So bad I had to go back to the 50.

    How long does it take to taper down with minimal side effects? Does anyone have advice? Headaches I’ve lived with most of my life, but the nausea, BRUTAL. I cannot handle it. Your thoughts are really appreciated, anyone?

    • Charles ( UK ) August 1, 2016, 11:10 am

      Hello Kathleen, I went from 100mg down to 25mg in a month reducing my intake by 25mg each week, then I stopped altogether, this was ok’d by my doctor.
      I’ve been off them altogether for a month now and the worst thing I got was the ever so slight feeling of a cold bubbling under, hot flushes for a while, some leg cramps at night but that was it.

      I took quetiapine for three years probably and it was getting me to sleep at night but at what price? My suggestion for what it’s worth, and this helped me when I detoxed, on my own from co-codomol, (after surgery five years ago)… Get a juicer and get some apples, celery and carrots down you every morning, get out and walk, and get some fresh air in you.

      Small things I know but you can’t just treat the body on it’s own, the mind must be nurtured too. I’d recommend a book by Mark Williams called, ‘Mindfulness’… I can’t say enough good about it. Also, be kind to yourself, don’t feel angry or resentful but keep in mind that you WILL get off the quetiapine …it might just take longer.

      I was lucky, I have never smoked, never done recreational drugs and packed in alcohol years ago (bored with drunks). In many ways I had a clear run at it. Hope this helps. ‘May you be happy and free from suffering’ :-) Charles

      • Kathleen August 6, 2016, 9:26 pm

        Thanks Charles. I am trying to cut down again as of this week. I am going every other day 50 – 25 mg. I think I’ll do that for a couple weeks, then stop. Thanks for your good advice. Well received. Take care.

    • Tilly August 1, 2016, 12:32 pm

      I’m in this boat too. Tried to cut down from 50 to 25. It’s been 3 days of vomiting, nausea, eye pain, head pain. :( Apparently if you wait weeks between tapering down again it helps…

  • ELIOT July 25, 2016, 11:50 pm

    I was put on Seroquel for sleep issues in 2008. It worked great for 9 years, until I developed fasciculations in my left wrist. This condition is not uncommon for people who have taken the medication 5+ years and are older (I am 58). However, they can also be a sign of ALS, so I had to find out. So, on my own, I decided to stop taking the medication to see if the condition improved.

    Two weeks after starting to taper, I am taking about 6mg per night (1/4 of a 25mg pill). The fasciculations have gone away. I have lost 3+ pounds without trying. That’s the good. Among the side effects I’ve had are irritability, confusion, sleep issues and itching. We’ll see what happens when I give it up completely.

    I think it’s been easier for me (so far) than the stories above – but this stuff is scary bad. I am very sorry for everyone who is struggling to get this drug out of their life. Good luck all.

  • Misdiagnosed July 24, 2016, 1:40 am

    After 14 years with the same Dr, I switched. Glad I did. To shorten a very long story after several sessions my new (ER) doc decided I’d been misdiagnosed with BiPolar Type II 14 years ago and never should have been put on these meds. So, I’m right now doing a long taper off of Seroquel (then I will attempt a taper to at least lower my Clonazepam dose.

    I had already lowered it without really meaning to from 4mg to 2mg a year ago by not taking meds I was so doped up!) My old doc at various points had me up as high as 400 Seroquel (and 600 Topamax) in addition to the 4.0 clonazepam. I had lowered on my own the Seroquel to 300 (and the Topamax to 400–those were levels I’d been at for years–I don’t remember why she increased, but she never would listen to me say we needed to go back down, so I finally left).

    My new doctor is an experienced CLINICAL Psychiatrist, but hasn’t held sessions in a while. She hasn’t had a patient have problems come off of Seroquel before (to the point I needed to take Phenergan suppositories so I could attempt to keep eating and drinking) so I’ve been bringing in research papers to her. We worked with a compounding pharmacy to develop a liquid I use to titrate my dose and be able to go off much slower. I also found out the hard way that if I hold at a dose (say 100mg) for too long, and then try to resume titration get off, the nausea comes back horribly!!!

    I’m now under 50mg, and titrate off about 1-2mg every week. When I get closer to 0mg we’ll see what happens… and how I handle going the entire way there. Using the liquid I may break it down even smaller. Right now: Nausea is better, but I have little to no energy, sleep is ok some nights, other nights nothing works. We are going to get me off of the Topamax next, then at least some of the Clonazepam. I know these drugs are helpful and needed to some, but they seem to have been developed horribly.

    My EKG says I may have had heart problems at some point in the past–I don’t remember anything, I’m 47 and a mom of two. I do know: this (all the meds combined and what I’ve been thru as a result) has destroyed my relationship with both of my kids–getting on the meds “trying to find the right cocktail”, being on it, and now getting off. I’m having to work very hard to rebuild things, but one is getting ready to leave for college, and I was diagnosed right after the other was born: they’ve always known me on some drug cocktail and never mixed good…

    I’m also having all the other Seroquel withdrawal issues–headaches, muscle probs, anger, etc. Im trying to peel back the drugs to continue to find the real me. For the first time in almost 15 years I feel me inside but it is hard. I’m encouraged by some of the comments regarding the Seroquel withdrawal–and please be encouraged by mine. I started at 300 mg and in 10 months I’m now under 50 mg. BUT I had to learn the hard way at times to go very slow–and educate myself and my own doctor about everything.

  • Lisa July 22, 2016, 3:15 pm

    I went off 300mg cold turkey and am paying for it! Talk to your prescriber first!!! Sorry I did it. Now I don’t know what to do. Any suggestions?

    • Ray August 14, 2016, 7:26 am

      I would recommend (I know this is three weeks old, sorry!)

      1. calling your doctor ASAP
      2. going back on previous dose
      3. tapering off slowly

      For me 50 mg down every three days worked very well except sleep problems but I was on the XR version so that probably has a lot to do with it. How’s it going now Lisa?

  • Sue July 21, 2016, 7:55 pm

    I have been on Seroquel for years to control my rapid cycling bipolar 1. I started on 600 mg and am now down to 150, eventually planning to quit the drug completely. I tried going cold turkey and the withdrawal was absolutely horrible. The insomnia is merciless, I cannot sleep more than an hour at a time. My body cannot regulate its internal temperature, mind racing non-stop, weakness, muscle spasms, complete lack of coordination, diarrhea, and by day 3 the uncontrollable projectile vomiting starts.

    My body completely shuts down. The medical community is aware of all of this-that is why they emphasize the importance of not quitting your medication. The dangers of mental illness are very real, and quitting medication suddenly can be very damaging to yourself and others. If you are not happy with your treatment a good doctor will help you find alternative solutions-and if they don’t help you find a new doctor.

    I am now working with my doctor to taper off of Seroquel, and so far things are going well. When my dose is lowered it takes a few months for my body to acclimate to the new dose, but the transition is not disruptive to my life. This method just takes patience. Regardless of your chosen method, do not take this on alone. Have your support gathered around you: Doctor, therapist, friends, family, spiritual groups, support groups, etc…and if you don’t have anyone, then find someone.

    Best to all who are living with the struggles of mental illness, to all who have chosen to be proactive in their health by accepting treatment. In the future may we have better treatment options which only help and never hurt.

  • Ray July 17, 2016, 2:59 pm

    Incredible to see people’s comments. SO MANY OF THEM. I’ve been on Seroquel XR for two years, 200 mg. After a psychotic/manic break it was bumped to 600 mg. I slept 9 hours, took another hour to get out of bed, needed two very strong coffees to actually become awake, gained weight, you know the drill. And then the tardive dyskinesia started. First in my lips, then eyelids (go on, try to fall asleep while blinking non-stop) and then in my right shoulder.

    And at this point I broke. I told my CPN that if the shoulder doesn’t stop moving all the time I am checking out. She understood what that meant. First they added Akineton. Which did nothing. Then the taper started and I was given clonazepam to help with the TD. It did help but at 500 mg I needed five 0.5 mg pills to get through the day relatively symptom free. Now I am down to last 50 mg seroquel XR and 1 0.5 mg clonazepam pill.

    Withdrawal… for me it’s been such a mixed bag. I am dropping 50 mg per three days. The first night after lowering dosage my body’s like “sleep’s overrated, we’re not doing it”. I have to sleep though, I’ve got rapid cycling bipolar I. Two nights ago I called the psychiatric ER to ask what the hell am I supposed to do if I took maximum safe dose of zopiclone (22.75 mg), 10 mg of diazepam, it’s 1:30am and I am completely awake.

    They told me to call in an hour, and I fell asleep 55 minutes later – I know because I was checking if an hour has passed. :P Other than that… one day – completely suicidal, lost, confused, anxious. Another day – feeling great. Suddenly getting up before the alarm – this started happening at 350 mg. I thought it was my sleeping pills making it so hard to get up!

    I wake before 8, get out of bed and get on with my day without a drop of coffee! But the mental side effects… by Gods. Today is a good day, which confuses me, because according to previous weeks it should be hell. I’ve gone hypomanic and went to the gym 12 times in 14 days, mostly focusing on cardio and long sets/short rest weight workouts, to lose weight. Cut out sugar completely (on 600 mg I could eat a cake in one go, on 200 I lost interest in sugar, which is how I used to be).

    How much weight did I lose? NONE. Apparently it’s going to be like that until my last pill, which is tonight. I am preparing for the worst once I am completely off it. It’s such a ride, those last weeks. Some days I feel perfectly well, energetic, rested. Some days I am a wreck. Some nights – after dose drop – I can’t fall asleep without enormous amounts of sleep meds.

    Two nights later I need half a pill of zopiclone. Today has been diarrhea day. (Rejoice!). One more thing: tardive dyskinesia is almost gone – not completely – but also another side effect is gone: blurry vision. My optician couldn’t figure out what the hell was wrong, they gave me three different pairs of contact lenses to try, but no matter what, in the evening I’d see blurry – halos and that sort of thing.

    As I am lowering the dose my sharp vision is gradually returning. Keep on keeping on everyone, I’ll be back with an update in a week – unless I’m hospitalised or something equally fun happens! Last pill tonight! I am on lamictal 300 mg and I am continuing that – I have zero side effects, it works great on my depression and it’s one med out of a dozen or so that I tried that actually seems to do its job.

    • Ray July 20, 2016, 4:56 pm

      Three days later:

      THE GOOD: I am already losing weight. Today marks the first day since 2013 that I weigh less than 93 kg. I am energetic despite sleeping seven hours (SEVEN?!?!?! nine used to be my average). Mentally I feel stable, maybe a bit happier than I should be but I’m not going to complain.

      THE BAD: Falling asleep takes three zopiclones, which is concerning to say the least. Dry lips. Tardive dyskinesia, while almost gone, is still hanging around every now and then. Also I’ve now had a mild headache for five days and counting.

      THE UGLY: Diarrhea is a joy, isn’t it? Oh well. Maybe that’s the weight I’m losing. :P Also the allergy symptoms. I am only allergic to oranges. Well, now I seem to be allergic to air, and who knew one human being could produce so much snot? I sneeze in my sleep. Can’t decide whether to beg my GP for antihistamines or ride the snot wave hoping it ends in some sort of foreseeable future.

      Altogether it’s better than I expected. Not exactly a smooth ride but it looks like 95% of you had it worse. Hugs for everyone who would like ’em.

    • Ray July 24, 2016, 12:23 pm

      A week later: Allergic symptoms are almost gone. Weight is dropping – I had to tighten my belt three times this week (I’m working out a lot and eating low-carb, which changed exactly nothing while I was on seroquel – but now it does). Headaches are gone. Tardive dyskinesia is still a problem which worries me greatly as I’ve read it can become permanent.

      Sleep is still very problematic – last night I just didn’t get sleepy even though I’ve been up for 18 hours. Had to knock myself out with the sleeping pills. I hope this changes soon as I am worried about how many sleeping pills I need.

      No nausea or stomach aches although the diarrhea continues. I am eating less though – as if my stomach shrunk rapidly. I have the same breakfast every week – protein shake, oatmeal, fruit – and in the last few days I haven’t been able to finish it. It’s the same with other meals.

      • Charles ( UK ) August 1, 2016, 11:19 am

        Ray! I was encouraged to read your stuff… I’m doing well after a month off quetiapine. My symptoms were very few and I feel very, very lucky. Funny about the food, for me I’m eating SO well and look forward to cooking my main meal of the day, usually brown rice and veggies (steamed) with hummus and tofu.

        I’ve gone right off meat, right off chocolate and right off coffee…odd but I just don’t care for any of them any more. I will say that I do use half a zopiclone to help me sleep quite well, I also take one 5HTP tablet at night with my other meds, statins and heart medication… also Vit B complex.

        I occasionally get a hot flush, sometimes feel a sneeze about to happen and that’s it. Take care out there :-)

        • Ray August 7, 2016, 11:18 am

          Congrats Charles! :) I’m looking forward to only needing half a zopiclone – down to 1.5 right now (new update below). I hope it continues going well for both of us. I’m both very relieved that I don’t have ALL of the symptoms of withdrawal and really sad that most people get hit so hard. It was way easier for me than I expected. But I guess most people for whom it goes well don’t post here – why would they.

    • Ray August 2, 2016, 6:05 am

      Another week has passed… My mental state has been a bit all over the place. Well, I took seroquel for something, so it’s not that surprising. Depression paid a visit. Then something else happened: I got completely flat. I could literally lay in bed and contemplate the ceiling, and on occasion I did. Then a friend who also quit seroquel told me that it’s yet another sign of withdrawal.

      Sleep is still very difficult, and I am on maximum dosage of sleeping pills. I stayed up an hour longer last night and all I achieved was hurting eyes. I have enough sleeping pills for two weeks, but obviously this is not fun. Tardive dyskinesia seems to be slightly lessening. I told my pdoc I was no longer using clonazepam to control it and switched to akineton (which did nothing when I was still on seroquel) and she told me akineton can affect my moods.

      So I am white-knuckling through it, and the movements in my right shoulder seem to have dislocated something (? – like a shoulder-blade is sticking out) but it is getting less difficult. So good. 91 kg now. I’m exercising, eating well (and much less too), stomach has settled. Overall it really seems much easier than for most people here. Big hugs all.

      • Ray August 7, 2016, 11:26 am

        Another week passed… Weight is dropping – I am down to 90. That makes 3 kg in 3 weeks. Eating much less than before, small portions 5-6 times a day. Having enough energy to exercise, do things around the house, get out and see people. My mood swings seem to have calmed down – with my ultra-ultra-rapid cycling 9 days of stable mood is a good result, sadly. Flatness is gone.

        Still sleeping 7-7.5 hours and getting up refreshed. No caffeine. But I still can’t fall asleep without sleeping pills (managed 1.5 zopiclone last night by staying up an hour longer than usual, on the plus side I actually got sleepy). Tardive dyskinesia definitely lessening which is amazing, I was so worried that it would become permanent. Still happens, but less than before. Right shoulder getting better too, it’s still not quite as it should be but I no longer have this feeling that it’s dislocated.

        Oh yes, blurry vision is gone completely. I can’t believe how many side effects this med had, and they all creeped in slowly so I thought I was just getting old and that sleeping pills made it so hard for me to get up. I am not impressed by this at all. I am really not anti-psych but my life quality has improved drastically since I quit.

        Big hugs everyone. I hope you all get better, keeping my fingers crossed.

        • Ray August 14, 2016, 7:25 am

          4 weeks and 4 kg down :D Had to stop wearing my usual shorts as they’re dropping. Same with pyjama pants. I will need to replace half of my wardrobe as I got rid of most smaller clothes thinking I will never fit into them again.

          I also managed to go from 2 to 0.5 tab of zopiclone. Still sleeping 6.5-7 hours, which I am not used to at all, I got up two hours before my husband today. But I actually got sleepy last night, for the first time since quitting seroquel. Incredible.

          Tardive dyskinesia is almost completely gone. Still occasionally pops up but the movements are now happening for about 15 minutes a day (as opposed to HOURS) and they’re… gentle, if that’s the right word. I wish it would bugger off completely but I guess I have to wait a bit longer. Right shoulder is fine by now – I was so worried. Mood still stable. So all in all things are going much better. I just hope to never take seroquel again.

        • Ray August 26, 2016, 9:18 am

          Two weeks later… My weight loss slowed down. I was kinda hoping it wouldn’t, but then, 4.5 kg in five weeks is nothing to complain about, and I think 0.5 kg per week is healthier. Tardive dyskinesia is still happening :(. I now worry it did become permanent. It’s not terribly bad but it keeps on going. The blinking, the mouth movements and, again, the shoulder movements. NOOOO. My doctor doesn’t want me to take any more clonazepam or akineton to mask the symptoms, so I lay in bed trying to fall asleep while blinking non-stop. :(

          I noticed that clonazepam actually works like instant depression and sleep med at once since I quit seroquel – I took up to 2.5 mg a day when the TD was very very bad, now 0.5 reduces me into sitting on the sofa wishing it was nighttime and I could just go to bed and stay there forever. It goes away a day after but I am not exactly enjoying it. Sleep has actually dropped further.

          I sleep average of 6.5 hours and wake up refreshed and rested. 1 zopiclone is generally enough, but still necessary. Not getting manic though as far as I can tell, which is very good news. I now feel safe enough to get on with the process of quitting tobacco. I didn’t want to quit two things at once, since I feared the side effects so many of you wrote about, but I think I’m safe from those by now.

          My mood is pretty much exactly as it should be and I am hoping it stays like that. I really, really don’t want any more antipsychotics of any sort in my future. I know they might be necessary but the tardive dyskinesia is absolutely terrible. Does anybody have experience with quitting seroquel because of involuntary muscle movements? Did they eventually go away, and if yes, how long did it take?

          Big hugs for all people suffering – I hope you all get better soon.

        • Ray September 2, 2016, 5:43 pm

          This is probably going to be my last post for a while, I’ll try to remember to come back in a few months. I am yet to notice any negative effect of quitting seroquel past the initial period. My sleep averages 6 hours, so it dropped even further. No manic symptoms detected though, and I am energetic. My weight, which stayed around 88.5 kg suddenly decided to plummet – down to 87.5 in two days. Hmm. Oh well.

          Not too upset, just had to tighten my belt again. That means 5.5 kg down in approx. 6 weeks. Mood swings are present but to be honest they are pretty much always present no matter what meds I am on. (Currently only lamictal). Tardive dyskinesia is the bad news. It is not gone. It’s much less of a problem, but it persists.

          My CPN tells me that it should be gone by now and since it isn’t it probably became permanent :((( even though we acted on it really quick. NOT HAPPY. I can live with this level of TD disturbances. But… had I known earlier… I don’t think I would have agreed to take this med. :( It helped when I started it, it really did help. But I should have stopped as soon as it was possible. And I didn’t know that.

          As usual, big hugs to all the sufferers, and I hope things get easier for all of you!

        • Ray October 21, 2016, 7:44 am

          Last one from me… It’s been over three months. 8 kg down. Back to normal 8 hour sleep. 1 & 1/2 zopiclone does the job. My blinking persists but it is getting less irritating with help of propranolol. I actually miss the mental help I had from seroquel. Not the side effects! Not the weight! But it helped me stay stable.

          I had a very serious crisis a month ago and actually refused to call crisis line because I thought (my brain wasn’t exactly clear) that they would give me seroquel and I didn’t want that because now I already have permanent tardive dyskinesia which is fairly minor and I REALLY don’t want it to become major again. Good luck everyone. I’ll keep you in my prayers.

          • Cate December 24, 2016, 11:45 pm

            Ray, I’ve really been moved reading your account of your Seroquel taper. I’m wondering how you are doing and if the TD has changed at all. I saw a girl on Youtube who had bad TD and after 2 years it was barely noticeable. Hugs to you.

  • Jeff K July 14, 2016, 9:19 pm

    I wish people would read this article and the comments section BEFORE they start taking this drug and then decide IF they still want to take it. Unfortunately, psychiatric nurses won’t tell you anything about the withdrawals, and few of them will tell you about all the side effects of the drug. I learned the hard way after quitting cold turkey, but there is hope. After 5 months of withdrawal symptoms, I’m free of it and I feel okay. Cognitive Behavioral Therapy helped me far more than the drugs ever did,

    • Kathleen July 16, 2016, 8:42 pm

      Unfortunately Jeff, I wish I had known it existed. I would have felt a lot better knowing most of my symptoms and side effects were because of this drug. Plus having to go back to my psychiatrist every 4 months, he kept me on it insisting I needed it and I’m still going back regularly. I don’t get why. I hate being on anything. I don’t feel as though I need them and when I was put on them, I was going through a very dark emotional time thus reason for my breakdown. I wish I knew.

      • Kathleen July 16, 2016, 9:01 pm

        Update: I went from 100 mg down to 50 over a two week timeframe. My symptoms were a lot of headaches and stomach issues. Nausea and acid reflux. They are better now that I’ve been at 50 for a week. I intend to taper more till I get to NONE. I’m trying the slice off a little at a time. Hopefully I will remain symptom free.

  • BeenthereDonethat July 14, 2016, 2:52 am

    I couldn’t get my Seroquel script renewed for 4 days and it has been the worst week of my life! This HAS to be as bad as heroin withdrawal, and it takes forever (months!) to get rid of withdrawal symptoms! I was nauseous, vomiting, had no appetite, slept during the day and night, sweated big time, my joints hurt, my eye hurt, had sinus problems, was irritable, and lethargic.

    But I really feel normal for a change, I feel like me. I was taking around 200mg a night and it seemed to be doing less good, even for insomnia which was I felt the best advantage of Seroquel. So, I’m going to try to stay off it, or at least withdrawal gradually because I’m tired of not being me, and I don’t want to go through this again!

  • Mystry July 11, 2016, 8:27 pm

    Please help… Does this all finally come to an end??? I was on 800 mg nightly for over eight years along with 1000mg of depakote and 200mg of pregabalin. I withdrew over the space of 5 weeks realizing that I wanted to see how I could function as a member of the human race after being on medication for over 14yrs!!

    I couldn’t work out what was going on with my physical self as in my mind I feel ok but with the constant nausea, vomiting headaches diarrhea terrible sleep mood swings, light and sound sensitivity etc etc etc I still can’t quite believe nearly 3 months down the line I’m still no closer to feeling any better???? I’ve had an endoscopy, blood tests, stool samples, ultra sounds, urine samples all showing nothing!! Until I found this page I thought I was totally on my own and Drs have repeatedly turned me down for help with everything as nothing shows so there obviously isn’t a problem in their eyes.

    Constantly I questioned whether this was the results of my withdrawal and the Drs point blank replied with no as the meds would only take a week at most to get out of my system. So 3 months later still waking everyday sick as a dog and almost hourly questioning whether I should get back on the damn seroquel!! Trying to work and purely just live is a terrifying concept when everyday I wake up praying it’s going to get better and it doesn’t.

    How can this possibly be right?!! So again please someone provide me with the hope that it does stop?!?!

  • Kathleen July 5, 2016, 10:44 pm

    I am so happy I found this forum. And am so grateful to find so many people in the same boat willing to share. Everything everyone says hits home so much. I had a breakdown 6 years ago and was put on Lamictal and Seroquel. Very high doses. I am still on both, however, doses are lower. I gained over 30 pounds. Lost some on Medifast 2 years ago, but 20 has come back, so am trying again. So so hard.

    I feel completely drugged with a hangover every morning. My husband is finally coming around to realize its these damn pills and not a thing I can do about it. No motivation, no energy, complete brain fog. All on a constant basis. I’ve decided I’m going to wean myself off of Seroquel, especially after seeing all of these posts; doctors approval or not, because I cannot stand feeling this way.

    I’ll stay on Lamictal as it has no side effects that bother me except the occasional lamictal headache”. I realize having the breakdown was a culmination of events in my life at that time, not that I was “crazy”. I talk to a therapist regularly and with her help, feel that half of these meds are not necessary. Maybe they were at the time, but certainly since my situation has improved, don’t feel they do anything different.

    He also has me taking ativan as needed which I take at bedtime and now that my blood pressure has been going up steadily, my internist has me on a beta blocker as well as 2 other meds. I found I have to take that at night as well because during the day, well, I might as well not get out of bed at all.

    So minus the Seroquel I hope I have no sleeping problems, and hopefully will start losing the weight again. I’ve been on Medifast for the past 3 months and have only lost 12 lbs. I should have lost at least 20. Its so restrictive. I am so grateful everyone shared their experiences here. I don’t feel so crazy or alone anymore.

  • Ted June 29, 2016, 7:52 pm

    I am, and oversedated on 200 mg of Seroquel, 1200 of Neurontin, 1 mg of Klonopin and 300 of Lamictal. My major concerns are pre-diabetes and constant oversedation. I have been on them for about 3 years. I have gotten off of three of them before – It was difficult.

    I can’t seem to come up with a plan of how long to take to get off of them, or in what order to do it. My doc told me I would never get off all of them, and that did not make me happy. I want to replace taking meds with exercise to maintain mood control.

    I tried a 50 mg drop in Seroquel last month, and it was too much. I was in withdrawal within hours. I would love to be off all of them and doing well 10 days before I see him in the middle of September – that is 65 days from now. How do do it, in which order and stay stable mood wise and experience minor withdrawal??? Any thoughts?

    • Ted June 30, 2016, 5:25 pm

      I didn’t change my Seroquel amount by 25 mg last night. Instead, I split up my Lamictal dose to 100 mg three times a day yesterday, and today I am going to try to go twice a day with the Lamictal 100mg. This may be too much of a jump – but I will adjust. I did sleep well last night and woke up feeling less groggy – but I am still way oversedated at night.

      I am thinking of trying to spread my meds out a little more during the day instead of taking them all at night. Given the very short half life of Seroquel, this strategy may aid me getting off the Seroquel. I could evenly split all the meds into three times a day – but I feel like that might oversedate me during the day – but if I did and then started to adjust downward slowly.

      I might have more success and less withdrawals – especially if I try to take a little time to get off all of this stuff. I don’t want my depression to increase, so it is all a balancing act that I have to be very careful with. I think I will only drop to 250 of Lamictal today instead of 300. That is a safer plan. Prayers for all you out there who are on this thread. Ted

  • hannah June 25, 2016, 10:23 am

    I have been on seroquel for 12 years and I am only 22. I am a diagnosed bipolar and I have no idea how to function without this medication… and that scares me. My doses have ranged from a total of 1100 MG to now my lowest dose of 400 MG. Sounds crazy doesn’t it I have been prescribed the XR and regular.

    I would like to change my medication to a less powerful medicine but I am afraid of being unregulated in my daily life. I am a mom and am employed full time as a preschool teacher my medication makes all this possible I am terrified that withdrawal and the period needed to recover will possibly have a huge impact on my family and work. I’m currently in a withdrawal due to neglect to refill on time and it really makes me realize how much my body needs it…

    I vomit, shake, eradicate mood swings, my stomach is in an uproar. I also experience extreme insomnia and my body muscles clench and release. It’s hell I need to think about the long run I’m going to be medicated my whole life and I really would like that medication to not be so powerful over my health. If anyone has medication that has worked for them to switch to from seroquel I’d love to have the name.

    Good luck to all of you out there trying to get regulated. I hope our lives stay steady.

    • Ted June 29, 2016, 7:55 pm

      My thoughts and prayers are with you Hannah. Don’t ever give up your hope of getting to the cause of your symptoms and eventually getting off the meds safely and slowly. You win if you don’t quit.

  • Judy June 25, 2016, 2:47 am

    I was on Seroquel from 2009-3014 800 mgs in Minnesota. When I moved back to Massachusetts it went down to 200 mgs. I gained a lot of weight. My doctor tapered me off and put me on trazodone. My last dose of Seroquel was about 3/12 weeks ago. 3 weeks ago I got (sorry to say diarrhea) which I’ve had for 3 weeks, I thought it was a stomach bug.

    I’ve been nauseous also for 3 weeks. I’m also very itchy. I went to my primary. All she did was give me some cream for my bottom. Last week I went to the hospital. They gave me fluids because I was mildly dehydrated. My blood work came out ok. I’ve lost over 10 lbs in 3 weeks. I can’t really eat. Lots of freeze pops.

    I have an appointment with my gastroenterologist on Tuesday. Reading all of these posts it maybe sounds like withdrawal from the Seroquel but not sure. Interested to see what the gastroenterologist says. I’m guessing he may do an endoscopy. I’d like some feedback to what people think. Thanks so much.

    • Ted June 29, 2016, 7:58 pm

      Judy… praying for you. Maybe your doc took you off to fast. Protracted withdrawal from S seems to be common. But it is good you are getting your stomach checked out. Keep up the good work!!!

    • BeenthereDonethat July 15, 2016, 1:27 am

      Do you really need to go to a gastroenterologist after reading about hundreds of people posting here that have nausea and trouble eating after withdrawing from Seroquel? Sometimes, from what I’ve read here, the nausea lasts months.

  • Chasidy Kenerly June 20, 2016, 12:38 pm

    I wanted to share my experience coming off Seroquel to hopefully encourage others. I was put on Seroquel as an add on to my SSRI for OCD/Depression/Anxiety. I hated the side effects from Seroquel. Joint pain, fatigue, blood sugar issues, etc. I only took Seroquel for a total of 5 months so my taper was much faster. I took 50XR for 2 months, doc advised to increase dosage to 150XR.

    I took 150XR for 2.5 weeks and had to lower back to 50XR due to side effects. I stayed on 50XR for 3 additional months and continued to have side effects. I went to 25 mg of the immediate release for 3 days and then stopped. The first week was bad. I was nauseous, anxious, itchy, upset stomach, had bad dreams and trouble sleeping. Benadryl really helped with the itching and falling asleep.

    After 7 full days with no Seroquel, I am feeling much better. I still itch and have diarrhea, but I feel so much better. I can see light at the end of the tunnel. I kept a journal to help me see improvements and prayed daily for help. I could not have survived this without my hope in my faith that God would see me through this awful time. It was still awful, but have hope. It will get better.

    • Ted June 29, 2016, 8:00 pm

      Chasidy. Congrats on what you have accomplished. Praying for you. The journaling is a great idea. I will incorporate that into my plan. Thanks.

  • Hannah June 19, 2016, 11:36 am

    Thank you to all the people that have posted. I thought I was going mad but reading this information and your experiences has helped so much. I don’t feel so alone, I know it’s the drug and not me, and I know it WILL pass. I reduced from 300mg over about a month and stopped a week ago. Have had bad dizziness, exhaustion, weeping, nausea, confusion, speech problems etc. But I’ve noticed that the evenings are starting to improve a tiny bit.

    Just want it to hurry up and go as missing so much of my children’s lives while I sleep or walk around like a zombie. Hang in there everyone. Each hour that passes our brains are slowly healing themselves. Be patient, accept your ill at the moment, and get as much help as you possibly can. I emailed this link to all my friends so they would understand why I couldn’t see anyone and just getting such kind and supportive replies has also helped me cope. Sending hope to you all.

  • Emma June 18, 2016, 2:56 pm

    Hi… I’ve been reducing my dose 100mg over the past 4 weeks.. I have taken one on alternate nights and now have started cutting my tablet in half repeating the same process. My sleep pattern seems to have got better this is now week 5. I’m feeling very good, my mind feels clear, I have more energy and am not experiencing any mood changes, I have been getting awful nausea and occasionally have vomited.

    My appetite is down but drinking lots. My GP prescribed me 20 5mg Valium tablets and I have not felt the urge to have to take one. I’m feeling positive for once (in 3 years). I personally feel that quetiapine made me feel awful, taking 50mg every other day still debilitates me.

    I’m slow to get up in the morning, usually vomit or feeling sick, takes me a long time to wake up and makes me feel terribly miserable… I’m hoping that I’ll be drug free, I’m going to wean myself off over 8 weeks. 3 weeks to go! Eeek!

    • Ted June 29, 2016, 8:03 pm

      Emma- Congrats on all the good work and being patient. Prayers for continued success. Keep us posted please.

  • Christina June 16, 2016, 9:43 pm

    Dear God – I have just realised what is happening to me. I am a very intelligent 65year old woman. I have been on Seroquel for 15 years. Want to know why? I was under severe stress and began to hear music. I did some research and it is not unusual for someone under such stress to have such a reaction. Anyhow my so called doctor put me on 300 mg of Seroquel each day.

    Before I knew it the music had stopped but my doctor left me on it to waste away. As long as I was quiet and took my medication etc etc etc. From time to time during those 15 years I would reduce the dose and I would see things at night in my room and even hear things – in no way did I connect it with this drug. So I went back on the dosage I was given because quite honestly I really thought I had some sort of a gift!! And I needed sleep.

    It is only now that I am coming off this poison that I can see that it was the drug causing these symptoms of psychosis. I came off it incredibly slowly over 6 months and guess what? I can hear music in my head, not only that but if I close my eyes I see pictures and my brain says words – yes it actually and totally independently of me says words and sentences in my head!!! – These symptoms are beginning finally to decrease after 8 months but it’s so very very dangerous to give people drugs which cause so much damage to your brain.

    I am not stressed at all now but yet I can still hear this inane music – it’s a bit fainter now but I have no idea just how long it will take. I would tell my doctor but her answer would be to be put on something else which would also poison my body – no way – I am not mentally ill!! Anyone involved in this scam which at the end of the day is about money should be locked up and the key thrown away.

    Doctors??? I don’t think so – don’t they take an oath to never do any harm??? Or am I in Alice in Wonderland? My advice to anyone experiencing any psychosis after or during the withdrawal period is to keep calm, realise you are sane and in time they will go. Also eat very healthily because good wholesome unprocessed food will feed your brain the nutrients it needs to recover. But always keep calm and know it is not you – it is the withdrawal symptoms.

    I’m lucky I haven’t ended up in hospital throughout all of this. Someone should pay for this.

    • Ted June 29, 2016, 8:12 pm

      Christina- thanks for the tip about eating well. I hope things are going well for you with your health. Prayers and keep us updated please. Ted. Tonight is day one for me.

  • Geminezmarie June 12, 2016, 4:47 pm

    I loved how I felt on seroquel but couldn’t handle the weight gain. I limited calories to dangerous levels and gained. It should be impossible. But I’m BP2 and nothing has stabilized my mood to a constant and happy state. I still feel normally and fully–I can grieve, empathize and rejoice like a normal human. Plus my cognitive functioning has been uncannily superior from memory retention to problem solving.

    Maybe it’s just regular sleep?! Anyway, to give someone hope, I was on 200 mg for 6 months. I cut the 200 in half for 2 days, intending to slowly taper but then went to 50 for 2 days and just quit altogether. Last dose was 9 days ago. I’m using Lunesta for so-so sleep but have had no other physical symptoms whatsoever. Except the loss of 3 pounds and expected insomnia.

    I do have lowered cognitive processing possibly related to the sleep change and I’m afraid my mood may be slowly dropping but hopefully from a Seroquel 9 to a Seroquel-free 7 and no further. I pray no soul crippling depression is around the corner as I’ll return to this medicine in desperation…

    • BeenthereDonethat July 15, 2016, 1:20 am

      Good luck! It would be rare if you don’t have debilitating withdrawal symptoms! I expect it will get a lot worse. Check back!

  • Saskia June 12, 2016, 12:47 am

    I had been taking seroquel since I was 14 I’m now 18, I started on XR and was taking 1200mg of that a day and then switched to 600mg of normal release. Eventually I got down to 300mg no problem. I acquired panic attacks from the seroquel and quit cold turkey. I was apprehensive and the first 3 days weren’t great but weren’t as bad as they could’ve been. I woke up in sweats and felt tired but I ate healthy and relaxed and reduced caffeine intake and that helped my symptoms subside.

    After 4-5 days my blood pressure and heart rate went back to normal and so forth. I understand it is dangerous but compared to everyone’s bad cold turkey experiences I honestly think it’s a lot to do with your mindset and what you do while withdrawing. Keep busy and eat well. If I can do it after 3-4 years of being on the drug on high doses anyone can. I suggest regular doctors visits while withdrawing to minimize risks.

    • BeenthereDonethat July 15, 2016, 1:17 am

      LOL! Yeah, psychosis is just a mind set, too! How ridiculous! Do you tell that to yourself when you get the flu, too? That it’s all in your head, that you just have to buck up and pull yourself out of it? I can see you doing the same thing if you got terminal cancer. You need to break out of your delusions.

    • Andrew July 28, 2016, 8:04 pm

      Saskia, I could reply to all of these postings relaying my experiences whilst withdrawing from Quetiapine, but I’ve singled yours out purely because of the negative reply you had to your posting. I hope it hasn’t caused you upset? The truth of the matter is that very few people really appreciate the power of mindset. There is a growing community that understand that negative emotion is the basis for all illness. Google e-motion-the-movie if you get a chance, well worth a watch. I hope things are going well for you.

  • daniel rayner June 7, 2016, 6:25 pm

    I’m glad there are other people who know what this is like. I have been on quetiapine 300mg for 12 years I attempted cold turkey but it was absolutely unbearable. I have now over the last 6 months been slowly tapering myself off of it. I am now down to just 12.5mg a night it has worked quite well and I have managed to avoid most of the withdrawal symptoms except for 2 agitation and insomnia.

    I am barely sleeping at all. If I’m lucky I may get an hour or 2 and then I wake up again and am wide awake. Despite all this lack of sleep I constantly feel wide awake and my brain is racing at 100 miles an hour. I feel like a freak show! I hope my sanity returns soon.

    • Ted June 29, 2016, 8:13 pm

      Daniel- I hope this finds you well. Keep us updated and thanks for sharing some of your story with us. Ted.

  • Cliff June 3, 2016, 12:41 am

    My Doctor put me on Seroquel for sleep because he wanted me off Temazepam. It worked but after two years by blood sugar spiked to 400. My Doctor wanted me to start tapering off immediately. After about 6 weeks I’ve been totally off for two weeks. Even after tapering its been hell. I think I may be improving some.

    I had to start my temazepam back to be able to sleep. Nobody what anyone tells you, YOU HAVE TOO TO GET SOME SLEEP TO LIVE. Seroquel worked but at a terrible price I’m paying now. I am occasionally having to take a Xanax for terrible stress. Hot, cold, sweating, can’t stay still at times, and a host of other side effects. All that said I firmly believe we can all live to get to the other side of this thing.

    • Ted June 29, 2016, 8:14 pm

      Cliff – wondering how you are doing and hope you are feeling better. Keep us updated please. Prayers. -Ted

  • jessica June 3, 2016, 12:25 am

    I have been on 50mg seroquel for the last 8 months. My Dr put me on it to help with anxiety and depression. I’ve done my best to deal with the side effects of weight gain, loss of sex drive, and constant fatigue, but I just can’t anymore. I stopped taking it 4 days ago cold turkey and the nausea is terrible. It’s not to the point of unbearable, but it’s almost there. I’m doing my best to continue on.

    • Ted June 29, 2016, 8:17 pm

      Jessica- I hope this finds you doing OK. Keep us updated if you want to. Prayers- Ted.

  • Marty June 2, 2016, 6:00 pm

    I started feeling sweaty, so I took the 25mg I missed last night and will go back to my usual dose tonight and for a week. Then I will start a 25mg taper every 3 weeks. That will take me from 200mg at bedtime (non-extended release) to zero in 21 weeks.

    I have been on that dose for 3.5 years. That tapering schedule seems slow, but it will be much more comfortable for me and those around me. That will put me completely off by about 5 months. I hate this stuff, but I want to do this comfortably. Some may even say that this is too fast.

    So it is July 2, 2016 and I will be off before Christmas –Hallelujah– that is a great Christmas present. I will continue to get in better physical shape – really clean up my food plan and investigate supplements and do more muscle stretching, hydration and exercise.

  • Marty June 2, 2016, 4:11 pm

    I have been on 200 mg of Seroquel (not extended release) for about 3.5 years – taking it in one dose at bedtime. I dropped to 150mg last night. Maybe I should have gone only to 175mg?? I was able to get about 6.5 hours sleep last night but was up at 3:15 am. I stayed up until 9am and then napped until noon.

    My hands feel a little shaky and the first thing I did when I woke up from my nap was to eat half of a small watermelon. My hands feel a little shaky and I have a start of a headache. I will take Tylenol for that. If today seems a push, then I will back to 175 and do a slower taper. A lot of it depends on how I feel today and if I can get to sleep tonight on 150.

    Reading the article and some comments made me wonder about the effectiveness of this drug without continuing to go up on it. If the withdrawal can be intense, I wonder if there is an underlying hidden tolerance going on during long term use of Seroquel which makes the drug not work as well long term unless the dose is continually titrated upwards. I am going to get off of this drug safely.

    I know it is my tendency to not be patient and do things too rapidly. I really would like to handle the drop to 150 well and not have to go back up to 175 or back to 200. I will see. I am going to hydrate well and really working on the increase my daily exercise. I think both are really key – especially so the hydration.

  • Rachel McCain June 2, 2016, 12:24 am

    I’ve been on Seroquel for 11 years and I am still currently take it. (300mg) I’ve had two scary episodes happen to me from just running out of my medication. In all three instances within 48 hours I experienced EXTREME INSOMNIA and PROJECTILE VOMITING. I was so DIZZY it was horrible. When I was younger I was at work once puking, dizzy and on no sleep. My mom was able to find half of a 300mg pill.

    I took it and within two hours I was feeling normal again. What bothers me the most is just how quickly the withdrawals slam you. I asked my doctor to please take me down to 300mg to 200mg with the hopes I can one day taper off completely, I’m a 33 year old female and was originally prescribed it for severe sleep issues. I sleep amazingly well on Seroquel, I absolutely cant fall asleep without it though.

    I don’t know what my future holds but I do know I don’t want my body dependent on a drug if I don’t have to be. The withdrawals were so intense they made me unable to function at all. And thats not me quitting it cold turkey that’s me missing a full dose (300mg) for one day. YIKES.

  • shirley vanwagoner May 26, 2016, 12:35 am

    This medicine has been a nightmare for me. I have gained 100 or so pounds and have been on this for almost 12 mos. I don’t even know what I’m doing and stumble into the kitchen and eat uncontrollably around midnight then go back to sleep. I am trying to taper off but have agitation and am sick to my stomach and cant think right. I wish I would have never been prescribed this medicine, it is just a plain out nightmare. I have only been tapering off for 3 days, cutting the dose in half. I’ve been on 200 mg. Then I will go every other day, then try to quit. :(

  • Dawn May 22, 2016, 7:56 am

    I was on 200mg of Quetiapine. I tapered off it. The only problem I had was being unable to sleep. It was still going on 2 weeks later. I now have to break a 25mg tablet in half and that works but it makes me think I’ll never be able to come off it fully.

  • Christina May 21, 2016, 4:30 pm

    I was put on Seroquel 15yrs ago because I was hearing music in my head – you know what? It was stress, I am very creative. It’s ridiculous to say the least. During that 15 years my neighbors did what they liked to me and I caved in. I am a very intelligent woman – being on this drug took any intelligence I had away from me, I could not see the wood for the trees. I have come off it now and have stood up to my neighbors – one of them has moved thank god because she couldn’t get her own way.

    The other is close to losing her home – the sooner the better. Words cannot describe my disgust that doctors are handing these out like confetti. I was on 300 mg each day – now I do not take it, I began a very very slow withdrawal from them last November. My anxiety kicked in, but I started my own business, took up hobbies, am a writer now and a Master Reiki practitioner all in the space of 2 years.

    You can do this, if I can at my age you can too – just don’t do it quickly. Never go cold turkey with this poison. I am on loads of supplements now and am vegan – that is helping a lot. I have today started also taking ashwagandha – and the dammed music which by the way returned, is now decreasing at times. It is only there now because I have been through a hell of a lot of trauma due to my standing up for my rights and losing my son.

    It’s stress and anxiety which I suffer from which means that I need a much quieter yet productive life. I am 65 years old and finally I can begin to have a life – I am fortunate in that I do not need to earn a lot of money to keep my home – my pensions pay for the bills etc. I do dog walking which only brings in pennies but its a little bit extra for me to get nice things. I rue the day that I was put on it.

    When you come off it be sure to eat well, get exercise and take lots of supplements to repair any damage to your brain and body. I still have the anxiety but it is reducing bit by bit as I take better care of myself. If the Ashwagandha begins to work well I will use that instead of chemicals for my anxiety.

    What I have also discovered is that I am Highly Sensitive Person and I pick up everyones feelings and I cannot deal with lots of stimuli at once – so in this fast paced world I will be very careful with myself. It’s all about money at the end of the day. Lives get ruined in an effort to do good. But these people who prescribe them need to take personal responsibility for they are doing to their patients – would they do it to themselves? No.

    • c.c. June 24, 2016, 12:37 am

      Hearing music in your head is entirely normal. Read Oliver Sacks’ “Musicophilia.” But I gather yours is unpleasant and uncontrollable. Maybe you can change it, especially as you find ways to relax.

  • Annie May 15, 2016, 4:41 pm

    Thank god I found this website – I thought I was going mad! I spent 7 years on this devil drug – 250mg XR for alleged bi-polar. Seven years in a fog, with no motivation and feeling sleepy all the time. I quit cold-turkey seven days ago (my own decision), and it has been brutal, despite the Psychiatric Nurse telling me there were no withdrawal symptoms.

    Hot/cold sweats, no appetite at all, severe nausea, vomiting, diarrhea, insomnia, shakes, dizziness, total lack of energy, and headaches. The first three days, I would cry uncontrollably at anything. But things are starting to get better. The ‘mind-fog’ has already lifted. The crying has stopped, and the hot/cold sweats are nearly gone.

    My appetite still hasn’t come back, but maybe that’s not a bad thing because I gained 48lbs taking this poison. I truly wish that I had never started taking this stuff, and I am hoping that things get easier from now on. Good luck all.

    • Kevin Kroft May 16, 2016, 4:38 pm

      I am about a week into dropping 300 mg of Seroquel cold turkey. I had a few restless nights, sweated a lot for the first 5 days, and my appetite has been a bit low. The drug was prescribed for possible bipolar, to control hypomania. Taking it, I gained about 20 lbs, and was very drowsy in the evenings and mornings. I am on anti-depressant medications as well, and I think it was working against them. I also began rTMS treatment 3 weeks ago. Overall, a bit of an uncontrolled experiment, but my general mood seems to be improving.

      • Kevin Kroft June 28, 2016, 6:02 pm

        Update… I’ve been feeling steadily better since dropping Seroquel, and continuing with the rTMS treatments. My appetite is still a fair bit lower, and I’ve lost about 15 of the 20 lbs I gained while on Seroquel. I’m sleeping well, plus energy levels have returned to normal.

  • K May 12, 2016, 2:41 am

    I’ve been on this medicine for a long time. It was prescribed to me, I was too young for a say in any of it so I took it. I was forced to believe something was wrong with me, when there wasn’t anything wrong warranting the uses of this medication. I suffer from panic and anxiety. Which I had medication for to begin with.

    I was thrown on this because people didn’t like the results they were seeing in me. My new doctor said “I don’t even know why you were on this”… I stopped a few days ago. I was taking a low dose, because I’d rather use natural remedies then medicine that initially will destroy you. I’m nauseous, crying over absolutely nothing, not sleeping, sweating, and panicking like nobody’s business.

    My anxiety has increased like to tomorrow. I can’t even think straight. My mind is racing.. I ASKED MY DOCTOR IF WITHDRAWAL SYMPTOMS EXSIST WITH THIS MED, was told NO. Do it cold turkey. Do NOT fall for this. Try natural pills and supplements… Don’t give anymore to these greedy people of medicine. You take something to feel better, you get better, get off it and feel worse than what you first started out with.

    I’m all for mental health awareness. But I feel were suffering more than we should. I’ve been drinking so much water and juice in order to cleanse myself. Exercise makes me more dizzy than I already am at this point. I’m praying and meditating. I’m trying to get my life together. I’m going to be 20, and I feel like it’s going to spiral because the after effects of these medications I need to come off of.

    Do not cold turkey anything!! This will end eventually, there is a light. Just can’t see it yet.

  • Rupert Simclair May 11, 2016, 8:11 pm

    I’ve come off 75mg Quetiapine and I can’t express how low I feel. I’ve had chronic back pain which normally wouldn’t have. Had endless nights of no sleep and I can’t settle or relax for more than 5 minutes. I feel suicidal which is not my style. I’m so worried what I can do because I can’t cope with the low moods in which I’m having. I’m scared about my future.

  • Stephanie May 8, 2016, 11:01 am

    I have been taking 400mg for five years. I just found out that I’m pregnant and the doctors said I had to quit now! I don’t know how I’m going to get through the next eight months with these withdrawals. Something has to give.

    • hannah June 25, 2016, 10:37 am

      It’s dangerous even on a low dose. When I got pregnant with my son my doctor wouldn’t let me go completely off the medication they told me the side effects were unknown and that it was best for my baby to stay on a low dose I went from 800 MG to 400 MG. My son is now 5 and has various different special needs including autism, ADHD, and a learning disability… he also wasn’t able to breastfeed due to the Sedation Factor. Good luck.

  • Rebecca May 7, 2016, 4:33 pm

    This is my first night without 300mg quetiapine, I am sick to death of being so fat, of starving myself, working my ass off to lose 3 pounds, it’s a joke. Been on it for 3 years. It did help when I needed it but I hate myself for all of the weight gain and feeling like a zombie!! I wish I had never touched the stuff but here goes. I also take 300mg of trazodone which I am going to stay on for now. I am diagnosed with borderline personality, PTSD, depression and anxiety. Will update tomorrow.

  • Chick pea May 4, 2016, 12:45 am

    I’m 26 and female. I have been on Seroquel for almost 3 years now. 400 mg a day. Started to lower the dose a month ago and now I’m on 125mg twice a day, meaning 250 mg instead of 400. Next week it will go to 200 mg per a day. The side effects?

    1. Insomnia
    2. Concentration issues – BIG TIME. It’s kind of hard trying to focus reading Uni books or even trying to get myself away for TV…

    In Conclusion? No anxiety nor depression because I also take 2 other meds: Cipralex 20 mg, Topamax 50 mg.

    The other 2 meds are guarding the mood swings and bipolar behavior. And for almost 6 months my shrink has given me the green light to ditch the Seroquel in order to – in her words – “use a minimum meds as needed”. So I’m very thankful for this med, it did me good. It took the pain away, took the drama away from me, gave me a steady mood to build my life better. And now it’s time to say good by to the safety wheels, and treasure the person standing in the mirror.

  • Heidi Hoffman May 2, 2016, 3:41 am

    My doctor weaned me off of Seroquel 75mg for insomnia. Even going to 50mg one week and then 25mg the final week, I have had many of the withdrawal symptoms. It’s been 8 weeks since I weaned myself off. I am staying strong but it is so hard. I wish I never went on this drug.

    I was on it for 2 years and gained 30 lbs. I was sleepwalking and eating on this drug. Doctor put me back on ambien 10mg even though it does not work as well as Seroquel. I am no longer sleep eating and have lost 5 lbs. I wouldn’t recommend Seroquel to anyone and if you’re going to quit, you need to prepare for feeling like you have the Flu.

  • badattitud3 May 1, 2016, 6:27 am

    I was in the Hospital for 7 months then transferred to a care facility where I have been for 7 months and I’ve taken Seroquel 25 mg every night. I know it’s not a lot but it’s something. I just recently stopped oxycodone cold turkey and tonight is my first night without the Seroquel. I can only hope for the best. Thank you for sharing your comments.

  • Mark April 27, 2016, 4:29 pm

    Was taking 25 mgs for sleep doctor recommended 50mgs. First couple of days the sleep reenergized me then started to notice I was mentally slowing down so I stopped and ended getting extreme dizzy spells… Which led me here so thanks for sharing and to pay it forward I’d suggest not using this drug for sleep at even a low dose. Ty.

  • deris April 26, 2016, 7:10 pm

    Wow it has been a revelation finding this site! I have been on quetiapine for several years dose of 200mg. This was after a bad section of my life and with a 15 minute appointment with a psychiatrist. I have put on over 4stone and now am a diabetic. I was not told about any of these side effects.

    I have spent the last 3 years seeing a therapist and it has been a life saver. My whole thought process has changed. I have now reduced my levels over 4 weeks and yesterday took my final dose. I also thought I had a virus and the itching is terrible. The general fogginess when on this drug is awful, I have had trouble following storylines and taking in new information.

    I really feel that this drug is evil and no good for me. It is given without proper knowledge of the effects. I hope to be feeling better soon and able to feel myself and not so ‘separate’. Good luck everyone on getting off this drug.

  • Sammie April 21, 2016, 9:38 am

    This is my first day going cold turkey!!! I’m scared. I hate being sick. I hate feeling sick and shaky and dizzy. I didn’t sleep a wink last night. It’s made me gain so much weight. I’ve been on 200mg for 8 months. I’m so so scared about doing this. I smoked weed for 5 years of my life and I came off that no problem. I feel so unwell already and it’s only half 10am! Please tell me these symptoms won’t last forever. I have a 9 month old daughter to look after. I don’t wanna be to ill to look after her. Thank you. Xxx

  • Aj April 16, 2016, 9:39 pm

    I just want to start by saying if your being asked to go on seroquel don’t take this decision lightly. I came off quetiapine before I was on 850mg for severe bpd with psychosis. I tapered slowly and I stopped. I developed fibromyalgia symptoms and ME symptoms along with severe psychosis and depression so I was sent back on it.

    I was only on 300mg now it’s been a week since I stopped at 100mg and it’s not great. I have slept for days I have severe cramps and trouble going to pee. I have been on this evil stuff for 10 years and it’s that bad at times I’ve thought quetiapine would kill me. I used to have palpitations, my legs sometimes wouldn’t work and would feel too heavy, I’ve gone to sleep so out of control from the palpitations.

    I never want to take this medication ever again.

  • Aj April 14, 2016, 4:38 pm

    I have been on seroquel for 13 years. When I was first was on them I was on 800mg. Recently it started making me stiff all over so I decided to stop them. I gradually reduced them over time and I’m currently on 100mg and took my last dose 48 hours ago. I feel very sleepy and have slept a bit too much today. I wish I had never been put on these pills judging by these comments.

  • Lisa April 13, 2016, 3:14 am

    My soon to be 90 year old grandmother with early stage dementia is being given this drug. The doctor prescribed it when after two days into antibiotics from a UTI she wasn’t cooperating (so to speak) or sleeping well. 25 MG nightly at first, but just a day or two because I asked them to half that, which they did. Now she’s on half of the 12.5 and still having major issues.

    I feel so bad for her and tomorrow will be talking to the doctor yet again about stopping this horrific med. I’m afraid for her even more now after reading about the withdrawal. I was wondering if every other day for a tad would help ease her or is just getting her off cold turkey would be best since it’s such a small dose?

    Any dose of this is deadly and inhumane especially in the elderly with any type of memory dis-ease. Or anything for that matter.

  • J.d. April 11, 2016, 8:54 pm

    I’m a 68-year-old male trying desperately to wean off 400 mg gabapentin and 150 mg seroquel, both of which I’ve been using for 18 months due to chronic insomnia. This has been extremely difficult and my insomnia is out of control. When I’m able to sleep its for two to three hours. During that time I experience nightmares and sudden awakenings. I’m open to any suggestions. Thank you.

  • Chrysalis April 10, 2016, 8:24 am

    I have a love/hate relationship with quetiapine. I have been on this medication for around 15 years. When I stop taking it, I don’t sleep for days at a time. I was most recently taking 100mg nightly and decided to go cold turkey 5 nights ago. I am sick of being tired all the time and fed up with the severe weight gain.

    I didn’t sleep at all for the first two nights & managed to get maybe 2 hours of sleep each of the following two nights. I’m irritable and headachy. I am determined to finally be free of this stuff, but realize that its not going to be easy. I think that I’ve forgotten how to get to sleep on my own.

  • Suzy April 6, 2016, 1:27 pm

    Since diagnosed with borderline personality disorder in January, I was put on 25mg of quetiapine and gradually increased until now I am taking 200mg at night. I don’t like the way I feel on this drug. I feel permanently sedated, which is a nightmare when trying to hold down 2 jobs and study for a degree. I want to come off this medication, but am now really scared to after all of the experiences here.

    I cannot afford any more time off work and it sounds as if some of the withdrawal symptoms would make it difficult to go to work (vomiting, shakes etc). I was prescribed this after a 10 minute consultation with a psychiatrist and was not made aware that withdrawing from the medication can be a nightmare. I don’t know what to do! Cold turkey vs tapering?

    • Grishel April 12, 2016, 11:23 pm

      I understand Suzy, I didn’t know I was going to have such a bad withdrawal going cold turkey, I don’t recommend it, it’s just not worth putting your life on hold, the itching, the nausea, etc. is not something I will wish not even my worst enemy, I wish I knew about tapering… But then again I wish I didn’t take Seroquel at all. God Bless you and I hope you make the right choice.

  • Jacinda April 6, 2016, 5:53 am

    I’ve been completely off for 7 days now. I’m sleeping but I think the quality of sleep could be better. I have been taking temazepam but I don’t think it’s actually working. I still crave food in the evenings but it is getting better and I’m still peeing heaps. I really haven’t had any other withdrawal symptoms but I was only on it for 3 months. It’s been easier than I expected.

    • BeenthereDonethat July 14, 2016, 11:15 pm

      I had the same issue, it seemed to not be helping me sleep as much as when I first started. It helped my sleep less and less until I was sometimes staying up until 7am, although then I would sleep 8 hours. But I found out one thing by running out and going cold turkey for 4 days (of pure hell!) is that when you start again it’s just like it was in the beginning! I mean, I took only 100mg last night (my regular dose was 200mg) and I was out like a light in 10 minutes and slept through the night, just like when I first started taking it years ago.

    • BeenthereDonethat July 14, 2016, 11:16 pm

      Hmmm, quite rare. You are talking about Seroquel, right?

  • Jacinda April 2, 2016, 11:03 pm

    I’m on day 4 without any quetiapine and feel good. I’m having temazepam for sleep and last night I actually did sleep. My appetite is still huge. I’m feeling very relieved.

  • Devyn March 24, 2016, 8:58 am

    I’m 15 and have a mood disorder, no schizophrenia. I take 200mg at night and occasionally I don’t take it if I have to cram for a test. When I don’t take it, I don’t sleep at all and I get paranoia and mild hallucinations, mostly auditory (hear footsteps upstairs when we haven’t even used the attic in five years, knocking on my window, heavy breathing that can’t be mine or my cat’s, whispering when everyone’s asleep). Should I be concerned? Should I tell my therapist/psychiatrist?

    • Anne March 27, 2016, 9:57 pm

      It would be a good idea to mention it to your Psych. It’s probably some rebound psychosis from not taking it, but best to be sure.

  • carrie March 21, 2016, 8:09 pm

    I’ve been on Seroquel 300mg every night for about 4 years and I stopped cold turkey 2 nights ago. My mood has been fine but ive only got about 1.5-2 hours of sleep each night, been sweating a lot. I have some soreness/tightness in my throat and have little energy. But the main thing that is bothering me is my whole body twitching and muscle spasms and not being able to sleep. Does anyone know how long it usually takes to be able to sleep normally again?

  • Taylor March 21, 2016, 5:52 pm

    I have been taking 400mg every night for about 3 years. I’ve always had trouble with anxiety, depression, and was diagnosed Bipolar Disorder type 2 when I was 21 years old. I was once happy with my body, 5’4″ and 130 pounds. Now I weigh 202. This drug should be highly advertised as something that may cause you to gain weight of that magnitude.

    Seroquel has destroyed my life, yes it helped me sleep and helped with my mood swings, but my whole body image has changed to the point where it seems like a never ending cycle of being fat and depressed. Working out, watching what I eat, nothing worked and being bipolar can already make you feel like a freak, since it feels like no one ever understands the way your body and mind can turn against you, but gaining so much weight and not being able to lose it no matter what I tried is even harder to deal with.

    I quit cold turkey about 5 days ago and last night was the first night I got even a moment of sleep. The side effects have been horrible. Shakiness, anxiety, not sleeping a wink in literally 4 days and being happy when I even get an hour of sleep in a night. Just to rest my eyes for a second is everything to me right now. The stress on my body from not sleeping is also causing me to vomit all day long, makes me so sick I feel like I can’t stomach or eat anything, and has me so clammy all over my body that it’s making me shake and go from hot to cold constantly.

    I plan to keep on going though, my advice for anyone bipolar out there like me is to keep positivity around everywhere you can. Whether it’s watching tv, having friends or a significant other around, anything in your life you have to keep the bad stuff out. Do whatever it takes to cheer yourself up without going off the deep end and ending up in a mania of some sort.

    I hope this drug can be out of my system finally and hopefully feel as “normal” as I can and take control of my body and weight once again. If this post can even relate to someone out there, that would be a dream come true. No one should have to feel this way on their own. And anyone who just started Seroquel or is thinking about it, STEER CLEAR. I would never wish these symptoms upon anyone, it’s terrible. Peace and Love to anyone who reads this.

    • Anne March 27, 2016, 9:53 pm

      I have gained 20 or more pounds on this drug. I am tapering off of it. Have you tried Melatonin? I use Natrol 5mg with Theanine (they call it Calm Sleep) x 2 fast dissolve tablets plus 2-3 Calms Forte sleep aid to sleep. Yes, it’s a lot of Melatonin – maybe try one at first, but at least I sleep. I get DEPRESSED if I don’t. I was put on this for a psychotic break after going cold turkey off Klonopin – bad idea.

      A Psych put me on this 4 months ago. I’ve gone from 250 to 150mg in about 2 weeks. Each lowering of 25mg is about 4 days and comes with symptoms that aren’t terrible – mostly body aches and gastric. Today I feel some depression. Helped to cry. I hate feeling isolated BC of my weight gain. It has changed my face entirely – like a bloated mask. I can’t WAIT to be off of this and I wish you the best.

  • Jacinda March 21, 2016, 5:20 am

    Hi. I’ve come off quetiapine in the past and only remember having insomnia for a few days. This time I’ve been on it about 2 months and titrated from 50mgs to 300mgs at night. In 2 months I’ve already got high cholesterol and am putting on weight at an alarming rate. I also have been having problems staying asleep and so the psychiatrist added temazapam which she’s slowly withdrawing, but I think I’m hooked so I decided to come off quetiapine again.

    I cut my dose in half for about a week then cut it in half again to 75mgs after trying to go cold turkey for 2 days and not sleeping. Tonight I’ve taken 50mgs and hope that I’ll sleep. I haven’t been on it long so hope that things will return to normal pretty quickly. I have some mild anxiety but that is the only thing I’ve noticed after cutting down other than sleep being a bit hard to achieve in the next 2 or 3 days on each lower dose.

    I plan to cut down to 25 in a week or so then stop again. I will keep you posted about my progress. I really feel for those of you that are having such awful withdrawals but know that they will pass. Stay strong and hopeful.

    • Jacinda March 24, 2016, 8:00 am

      Hi again. Well 50mgs stopped me sleeping at all so this will be my second night cold turkey. I haven’t really slept for 3 days but I’m not feeling too bad. I was tempted to take 75mgs tonight but figure that could put me back to the beginning. I’m not having any more withdrawal problems so figure I’m pretty lucky.

  • Sofia March 19, 2016, 5:52 pm

    Hi everybody. English is not my native language, but I’ll do my best. I’m quitting Seroquel, 200 mg a day, cold turkey. I’m on day two. My three year old daughter is at her dad for a few days, so I thought I will get it done when she’s there. I’m bipolar, I also have generalized anxiety disorder and PTSD after being beaten for two years in a relationship.

    I feel cold, shaky, and having a headache. But that’s it. I’m so afraid that it will get worse. I’m a single mother and I can’t get “to bad” because I have to take good care of my child. Has anyone successed quitting Seroquel abruptly with just minor withdrawal symptoms? Good luck to everyone! And thank you for sharing your stories

    • Sofia March 21, 2016, 7:44 pm

      Updating: I couldn’t do it. On day three I felt so bad, in so many ways, that I had to take the medication. I will try tapering off instead.

  • Samantha March 15, 2016, 8:40 pm

    I stopped taking Seroquel 50mg last week I had been taking it for about a year and a half for insomnia, I went through 3 days of terrible stomach aches and throwing up with some headaches, I quit cold turkey. After a week of symptoms they subsided. I’m feeling much better after a week and I’m telling anyone who wants to quit this drug to quit it when you want to.

    I had fears for very long time that I wouldn’t be able to do it or serious things might occur. But if u can buckle down for about a week of stomach aches and headaches and not very good sleep, I promise you it will be worth it, it’s like I got my life back I’m not controlled by that sleeping pill, I’m feeling almost back to normal again, again tho this is for anyone who takes for INSOMNIA on low dosage levels.

  • Marty March 15, 2016, 8:28 pm

    Firstly I am so glad I found this page. I am on day 2 of quitting cold turkey after 6 years on 100mg. Yes my dose was low but I never realized I would struggle with such strong withdraws. It bugs me that doctors are aware of the effects this drug has on the body and yet still put people on it. All my best to you all you have all given me inspiration and made me realize I’m not alone in trying to get my life back from this medication.

  • Ron March 12, 2016, 1:14 am

    Last week my VA Psychiatric Nurse Practitioner took me off of the Seroquel I have been taking for 5 years. I was told to quit taking them and replaced it with Temazepam. I have had some horrible side effects all week, has been near impossible to work and honestly just feel horrible. I finally gave in and called her, I told her I was having some serious problems and major problems being able to work.

    I received both a bad attitude for 2nd guessing her and a response of “well most people can just quit no problems or issues”, go back to the Seroquel. From what I am seeing and have read on a pharmacy drug note this simply is not true and it is entirely advised to not stop suddenly. I don’t really know what to do as now I feel like I will have to take this medicine until my deathbed.

    Is anybody really having any success weaning themselves off of it over a certain period of time? I don’t trust my VA “doctor” anymore. Also forgot this tidbit concerning the itch, I was itching so bad 3 days ago I have 8 bruises on my right side by my ribs from scratching so hard. So yeah, these effects are serious.

    • Samantha March 15, 2016, 8:43 pm

      I had terrible itching to, these symptoms feel like they are never going to go away but trust me on this don’t go back to the pill, they will go away over time. What it depends on is you dosage level and how long you will be taking it, granted the higher the level and time you took the pill the longer it will take to come off it, but it’s completely worth it.

    • Anne March 27, 2016, 10:00 pm

      Wouldn’t be the first time a doc or nurse practitioner didn’t know what they were talking about. Sounds pretty narcissistic – double the fun. Can you consult with a Psych who is not VA? Can you switch docs?

  • Ty March 7, 2016, 7:41 pm

    I absolutely hate this drug. I’ve taken it for five years, with dosages as high as 1200 mg. I supposedly have ‘psychosis’ but yet I’ve been through the military and college, graduating with high honors and a 4.0 GPA. I don’t feel like I need this anymore and I would do anything to get off of it. I’m tired of my life revolving around a small pill, along with the stigma of taking anti-psychotic drugs, which has cost me jobs, relationships, and even places to live.

    Every time I quit whether it’s cold turkey or tapering I can’t even keep down water and I feel extremely sick. I’m not sure if the sickness is from the lack of sleep or if it is from the withdraw. I get irritated and foggy mind which hinders my ability to work or think straight. I can deal with all of the other symptoms but the lack of sleep is what kills me.

    I feel my brain shutting down and as soon as I hit what I call the “Drift,” (the area where your thoughts wonder until you shutdown and sleep) I bounce back to being fully awake. I don’t give up easily and I’m going to continue.

  • Amanda March 5, 2016, 6:19 pm

    I have been on seroquel for the last 6 years. Although it has helped a lot it also has caused a lot of suffering as I am now going through withdrawals. I was on a high dosage 1200 MG a day as I had been on it so long. And the sleep disturbance I have to say has to be the hardest thing to deal with. I haven’t slept in over a week with maybe an occasional dozing off that only lasts at most an hour.

    I hate this med and wish I had warned about how much it would affect me psychologically and physically coming off of it. Even with tapering the withdrawals are bad so screw it just cold turkey I told myself. Ugh…I’m in a constant fog and anxiety is so bad. But I really just want some sleep.

  • Chad Albus February 29, 2016, 2:21 pm

    My psychiatrists who prescribed seroquel to me did so within a five minute session and shared none of the important information about side effects and withdraw. I have come to loathe the practice of these drug pushing doctors. Seroquel was supposed to help my insomnia and mood swings. After a year I have developed such a tolerance that it has no effect on either.

    In fact, my mood and sleeplessness are back to where they once were. In trying to taper off I am experience the worst side effects and I am starting a new job next week. I feel trapped inside of a pharmaceutical hell. If you are not suffering from severe mental illness DO NOT take seroquel.

  • mark February 26, 2016, 9:29 pm

    Seroquel is harder to get off of and more addictive than narcotics. I am using the narcotics that I got after back surgery to get off of the stuff. I have taken Seroquel for years and couldn’t get motivated to do anything and couldn’t get off of the stuff. Getting off of the stuff by using narcotics may not work with everybody, and you would have to do it under a doctor’s supervision, but it seems to be working for me.

  • Jeny February 26, 2016, 4:24 am

    Hi fellow sufferers. I am so happy to find this forum. Need advice. I was prescribed SEROQUEL 25 mg in Jan 2014, 2 years ago and not ever given a good reason. I have all the worst side effects now including 25 kg weight increase. I am astounded at what has become of my life and my brain. I am seeing my doctor tomorrow and she is already on the defensive… such a small dose, blah blah.

    I intend to reduce slowly but don’t trust her advice. Can anyone tell me over what period and by what amount they have at least been able to survive this monster? Cheers to all.

    • lisa May 18, 2016, 8:01 am

      I have been recommended reduce 10 percent every four weeks! Slow I know, but the only way not to get awful withdrawal. I’m the same… put on a lot of weight on only 25mg.

  • May February 26, 2016, 4:11 am

    A couple months ago I suffered an anxiety attack that came out of no where. I was prescribed Ativan and Wellbutrin which gave me adverse reactions and I was diagnosed with “manic depressive/bipolar.” I sought 2nd opinion and later found out that I was hypersensitive to dopamine. Wellbutrin had only induced me with severe anxiety/GAD and worsened my condition.

    I was then put on Seroquel 50mg XR for a week and was increased to 100mg. The anxiety lessened but the side effects is unbearable! Even at a low dose I experienced rapid gain weight, felt stoical, continuous inflamed runny nose, my facial completion has changed dramatically, and it makes me feel like there’s something crawling under my skin.

    I am now being tapered off the meds and today is the last day of taking 25 mg, however, I am still experiencing the side effects and more. Today the itching started and this time not just my face but my entire body! I anticipate the withdrawals and I am looking for ways to manage them for it is only adding to my anxiety.

  • Christy February 23, 2016, 6:52 pm

    Hi, my name is Christy and I’ve been on 150mg of seroquel every night for the last year or so. Originally I took 600mg of seroquel every night for about 2 and a half years. I gained close to 65lbs in a matter of 3 months and I honestly couldn’t really bring myself to want to work out. I got off of the seroquel (no idea how) cold turkey. It was a long time ago so I don’t remember much of the experience.

    But basically I went a few years and then needed to get back on it due to increase in mood swings. I’ve been on the 150mg tablets every night for around a year or so now along with clonidine, lamictal, and wellbutrin and I’m feeling groggy most of the time, I have no motivation to get up and do anything, and I’m gaining weight again. I’m also having chills, migraines, nausea, and anxiety whenever I don’t take it or my prescription hasn’t been filled.

    So I’ve decided enough is enough. I tried cold turkey but for around 4 days I slept terribly, had muscle aches and migraines, and incredible amounts of nausea. I’ve puked a lot in this short time and I can barely sit or lay down without stomach pain. I didn’t feel like eating or drinking anything. It was too much to handle. So yesterday I made the decision to taper.

    I went from 150mg to 75mg (cut my pills in half) and last night was the first night I was able to eat a real meal and sleep through the night, with the help of clonidine (.3mg) and two tablets of Benadryl. Honestly for people who plan to get off seroquel, DONT QUIT COLD TURKEY! You will have the worst pain of your life and you will be miserable. Taper down to a super low dose and ease yourself into the transition.

    And remember, seroquel stays in your system for close to two days after you drop the pill. So keep that in mind when you decide to quit. Good luck :)

  • Hash February 21, 2016, 6:39 am

    Well this is my first post on any of these forums so please bare with my delivery. My post ended up being far too detailed so I’ve split it into sections. For those of you who want to cut to the chase, please skip to the last part :)

    I went into therapy for Depersonalization Disorder (DPD) sometime over a year ago. I started developing symptoms early on (from the age of 14 as far as i can trace) but went on to live a functional life, never feeling the need to seek professional help to address my condition. I did not even inform my family or close friends about how I felt and as the years went by, I became indifferent to my situation.

    I eventually started using street drugs. I was self-medicating and it actually appeared to be working! I started to feel good about my life, perhaps for the first time in my life up to that point. I was doped up, but once again functional – and happy.

    I found MDMA to be my drug of choice – it gave me “clarity” and simulated emotions that I couldn’t experience naturally. I began to abuse the drug and continued to do so until reality managed to find a way to finally shatter my illusion of happiness. I experienced an extreme drug-induced panic attack and was convinced that I was going to die due to an overdose.

    I literally did not even know what anxiety felt like due to my DPD and severe case of personal indifference and in this moment I was unable to understand what my body was going through. It was at this point that I realized that I needed to seek professional help to deal with my condition. I quit the drugs – all of them – overnight. I was ready to feel better. I was ready to take control of my life.
    Going into Therapy + Further Complications
    I started psychotherapy optimistically, with every intention of getting better. My therapist happened to be extremely “trigger-happy” from day one: I was prescribed Xanax, Lamotrigine and almost every SSRI in the market (as part of the trial-and-error approach to such medication). When i was not responding to any of the SSRI’s, my doctor abruptly shifted me over to anti-psychotics. By this time it had been a year since I had been in therapy and my shrink admitted that he had still not been able to determine an appropriate diagnosis for my condition.

    I was put on 400mg of Seroquel and for the first few days I couldn’t tell the difference between this new medication and the many that preceded it. Then one night – it happened again – I experienced a massive panic attack in the middle of the might and this time I could only think of this being a possible reaction to the Seroquel. My heart rate went up to 200 BPM and I had to go to the ER at 5 in the morning!

    I had once again experienced a drug-induced panic attack; only this time it was not at the hands of a street drug. I went to see my therapist the very same day and demanded that I be put off this medication immediately. Instead, he told me that I should push my dosage up to 600mg per night. I could not even imagine doing that to myself after the experience I had just had. When I insisted on being taken off the medication later on during the session, he told me that I was “not a suitable candidate for psychotherapy”… (those were his exact words, literally) and that the only way I could feel better was if I continued taking the medication he had prescribed for an indefinite period of time.

    It was hard to tell if I fired him at that point or if he had simply given up on me but it became clear that this was the last time I was going to be visiting him. Now it was time to kick this horrible medication on my own. I started by breaking my doses by 50mg after every five days. I couldn’t wait to taper this drug off, even if it meant somewhat rushing the process. I have now been off Seroquel for almost 1.5 weeks and I feel a significant improvement in my standard of living. I can once again think clearly, for starters.
    Cutting to the Chase – My Symptoms
    On the other hand I have been experiencing certain symptoms that I would like to address: while fatigue, insomnia and nausea are very frequent, the symptom that alarms me the most is heart palpitations. After my panic attacks (specifically the one I experienced while I was on Seroquel) I have had a constant feeling of anxiety, and even paranoia whenever I feel my heart rate is acting up. I started checking my pulse so frequently that a close friend of mine actually had to tell me to stop doing so.

    Now I just try to ignore this symptom, but it’s not easy. I can deal with the other symptoms but these bouts of uncalled for anxiety and palpitations have become embedded into my everyday routine. I would really appreciate it if someone with similar symptoms could guide me as to how to deal with them. Once again, this is my first time posting anything of the sort so I went through everything that was in my head. Thank you for your time and I hope everyone here has a speedy recovery!

  • Christine February 20, 2016, 8:47 am

    Everyone is different. I was on Seroquel, 50mg for three months after my psychiatrist overdosed me on lithium. I was thankful for the change then, that goes without saying. It kept my insomnia in check, a problem I’ve had a majority of my life. I thought it was helping but it was because the side effects included sedation. I got worse, my bipolar disorder increased in severity.

    I even started cutting again after ten years of keeping away from the blade. I was suicidal to an extreme. My therapist and family became concerned to the point of requesting hospitalization considering my horrible depression. I’ve quit the medication cold-turkey, whether it be the right choice or not, I made a dramatic change within just a few days.

    My personality did a complete 180° change and I have become better with no more cutting or suicidal thoughts. I am still in a struggle and will seek alternate treatment but for now the withdrawals suck with the headaches and nausea, but I want to live now. That’s better to me.

  • Michelle February 20, 2016, 8:16 am

    I stopped taking quetiapine after a six month taper down to 25 mg 2 months ago, I went through all the side effects: no sleep nausea, hives that came and went, sweats, anxiety and a range of other symptoms. My advice is definitely taper off over a couple of months down to smallest dose that can be sustained. Then under doctor’s advice, go off, but only if it is helpful to mental health.

    I have been losing half a kg per week have now lost 5 kg very slowly, no sugar and vegetarian, and low carbs. It has been hard, I still want to lose another 10 kg to get to a healthier weight. Two month after going off quetiapine I am sleeping about 5 to 7 hours per night, I still have constant hives but taking antihistamines so this helps. And have gone to a naturopath who has suggested synthetic melatonin and synthetic serotonin… not sure of long term effects of this but am taking the mixture she gave me.

    It has to be a total overhaul of diet, and exercise and relaxation and spending time on a hobby that gives you happiness, I paint. Good luck and yes it is possible to kick the seroquel habit but go slow to get to a point where the medication no longer controls you. And keep a diary of your improvement.

    I am 8 weeks off and the hives and sweats still bother me. But if you can distract yourself with activities, these symptoms will not be as intrusive. Do some brain games on your computer, anything to stay out of your head.

  • Elizabeth Gabriel February 19, 2016, 1:36 pm

    Going into my third week and a lot of the side effects are subsiding. Spent 10 days feeling carsick and constipation added to the nausea. Periodic profuse sweating and several sleepless nights. Still sweating a lot but no more nausea and up to 5 hours of sleep. Still drenched in sweat, but feeling better every day.

  • Nielsen February 18, 2016, 9:12 am

    I was prescribed Seroquel at 300 Mg since then over the many years of taking it I experienced so many symptoms such as a rash that would come on my arm and legs in a stereo symmetrical pattern and would burn and itch red. Warning this was terrible because neither the doctor or place I wen’t to with all there staff was oblivious to this now that I looked up the side effects of Seroquel I’m even shocked as of 2/18/2016.

    I first took this drug for bipolar one by the Orange County Mental Health in Anaheim starting in 2010 then went onto many places such as CHOICES, MHA, Telacare South, Telcare North. What amazes me is know one caught on that this medication was causing me more harm than good. The rash would come and go like a ghost in my body. I also experienced what I call a yo-yo effect in my appetite that connected with veracious appetite that was like a tug of war with symptoms of sleeping and and eating at the same time battling it out in my brain and body.

    This is what one will experience on it as well as getting off it. Be warned going cold turkey is hard as you can see what I’ve wrought. I made a conscious decision that my body was telling me this isn’t working out. The sleep was good but too much is not being normal. Having migraines full blown is awful weather you take it consistently or not they come out of nowhere depending on the situation or how your day is going.

    Back to having food? If you take this make sure you have a big bank account otherwise you will be miserable if your on SSI Disability. Why? If you don’t eat enough you feel like your going out of your mind fitting the urge to eat by the drug working in your brain and bloodstream especially after taking it and you knew you had enough to eat that day.

    I noticed the more you eat in conjuration with the feeling of deep sleep effect these merge together in hand and you eventually calm down after eating your heavy feel of whats in your pantry and kitchen. One word this is no way to live a healthy life. Tug of War, Sleepy going against the need to eat like a large never ending gut and brain that just won’t stop until it wins you over by eating so much that the sleep effect wears off. I’m keeping an open mind about this situation and have over a year or 6 month’s ? Have stopped taking it as a result.

    I feel a lot better I do have my good and bad days but at least I’m no wear near what I was experiencing a year and a half ago. My experience with Seroquel may not be like others out there. So be careful and keep your health in mind when thinking of slowly getting off it. I took long walks to wear myself out in order to sleep this seemed to help a lot. Also doing hard heavy chores to sweat this RX out of your system is good.

    Something to keep your mind off negative depressive thought and avoid people who are is good as well. Try hard as much to sleep weather you wan’t to or not. You have to get yourself back to a normal behavioral pattern in your life and overall thinking. I could wright more but I feel I have shared enough for right now.

  • fickletink February 17, 2016, 2:36 am

    I have been on Seroquel for 5 years now. My dosage started low at 25mg/day and an additional 25mg if needed. It slowly increased and at one point I was up to 250mg/day. I am now taking 150mg/day and intend on weaning myself off starting tonight. I think I will go to 100mg/day for two weeks and then discuss symptoms with my doctor at that time. I also take Effexor 225mg/day and Lyrica 150mg/day. I have been on Seroquel the longest and only want to wean off one medication at a time. I will update as I go. Wish me luck!

    • Sneaky February 21, 2016, 11:07 pm

      I had this problem too, fickeltink. Kept increasing the dosages. I highly recommend to anyone who takes seroquel to refrain from the temptation, though. I went from 25mg a night to 400mg a night, but even then I sometimes took more than I should have – up to 1,200mg on many occasions. However, after I’ve started weening off, it’s been surprisingly much easier to fall asleep than I thought it would.

      Doesn’t make much sense, but I figure that I never really needed to dosage increases in the first place. I just got so use to them working instantly that I felt I needed more if they didn’t – but I should have just been more patient.

  • Darren February 15, 2016, 7:09 pm

    I’ve just been reading all your comments. My Lord I hope you all eventually get off this stuff. I’m on 200mg twice daily and recently found out its PTSD that I’ve got and not bipolar. I’ve been given a 3 month appointment with my shrink. I’m not waiting that long before I start coming off it.

    I’ve only been on it 6 months so I’m praying to God that this is easier. I had withdrawal brain zaps when I converted from an antidepressant to quetiapine. That felt very uncomfortable and odd. I aim to reduce it slowly and surely by 25mg per go. I’ve yet to see my ass of a Dr to order some smaller doses.

    She thinks I’m nuts as it is so that’ll be a challenge too. I’m not staying on this shit anymore. A stone in weight added and low and highs that are just worst than I had before I started taking it. There is no reason for me to be on it so I’m determined to get off it. My work has suffered since being on it. Foggy isn’t the word.

    Complete dribbling mumbling existence is all I’ve had from it together with knock out lows and Scooby Doo highs. God bless you all for giving it a go. Don’t go cold turkey, it’s so dangerous. Gradually you’ll win.

  • Dawn February 15, 2016, 5:19 am

    My doctor had prescribed seroquel as an augmentation treatment for my major depressive disorder. I titrated up from 50mg to 300mg over the course of 4 days. I felt like I was drunk during those days, as my body was adjusting to the medication. It did not help my insomnia right away, and it wasn’t until after about the 6th day (at a dose of 300mg) that I went to sleep at night.

    But then I had a hard time staying up during the day, and generally fell asleep most of the day as well. Around the 8th day of the medication, I noticed my ankles and feet were swollen. At first I wasn’t sure if it was the medication, since it wasn’t listed as a side effect in the patient leaflet, but a google search indicated it was feasible and could occur as much as 10 days after taking the med.

    I called my doctor, who wanted me to wait a few days to see if the swelling resolved, he felt it wasn’t a common side effect at all. I also made sure I drank more water and watched my salt intake, but the swelling never got better. I called back, and he told me to hold off on the seroquel (cold turkey) for the weekend and call first thing Monday to report.

    The swelling in my ankles and feet has gone down after 2 days off the pills, but I am experiencing some of the withdrawal effects, which my doctor’s nurse told me I wouldn’t have (I did ask). I cry at nights for no reason, I get random sharp headaches, I feel so nauseated sometimes, sometimes I shake, sometimes I feel hot, sometimes I feel cold and get goosebumps for no reason, I am dizzy too.

    These started almost right away, and seem to get worse the longer it has been since my last pill 3 days ago. I was hoping that maybe I wasn’t on the drug long enough to have any problems, but I guess taking it for 10 days was enough. Now I wonder how long I will take to detox.

    I saw no benefit while I was taking the drug. It made me feel more apathetic and I moved slower and felt like I missing blocks of time. I would come home from work, and just sit in my car for no apparent reason. It was weird.

  • Tom Robinson February 13, 2016, 5:00 pm

    I have been taking 450 mg of Seroquel for several years — 50 mg daytime and 400 mg at bedtime. I quit cold turkey a week ago. So far, so good. Some insomnia, but good mental functioning, a little jittery. I was tired of the weight gain and the drowsiness. I went from 200 lbs to 270 lbs.

    I did a cost-benefit analysis and concluded that I would either keel over from a heart attack or stroke or deal temporarily with withdrawal symptoms and lose some weight. The weight is coming off. I’m eating a very healthy diet and staying active. Of course, remember, withdrawal is different for everyone. Not recommending my method to anyone, just telling my story. Thanks.

    • BeenthereDonethat July 14, 2016, 10:44 pm

      You are one of two out of hundreds here that have had minimal withdrawal effects from going off Seroquel. It’s kind of hard to believe you, TBH.

  • Melanie February 13, 2016, 2:47 am

    I was on Seroquel 600mg for 6 years and have tapered down to 300mg but can’t seem to taper any more without hellish withdrawals. Itching, no sleep, nausea, suicidal… Is it even worth it? Can it even be done? I hate Seroquel! I don’t think I can do this. I wish I didn’t want to die so bad.

  • Marcia February 12, 2016, 10:03 pm

    2 years ago I was prescribed the lowest does of Seroquel to help sleep at night. Not in my worst nightmare did I think going off cold turkey 3 months later all these horrible side effects and hospital visits could be from this drug. It is the only thing that makes sense since I am told I am ok? I have a family who I have to stay positive for but I am on the edge still of not being able to function.

    This includes brain tightening, numb feelings all over face arms, dizziness, concentration problems, night sweats, feelings of seizures or brain zaps, and much much more… Has anyone experienced this? It controls my life and I need some positive reassurance it will go away. Thank you. Marcia

  • Dan February 8, 2016, 10:37 pm

    After 10 months on this medicine I feel like a zombie when I take it, and just learned the pains of withdrawal when my pharmacy ran out of it over the weekend. I took it for insomnia, depression and anxiety. After reading what everyone else is going through too, I wonder how this is prescribed off label anymore. And thank God for insurance because one month would run $480.00 without it. I am going to see my doctor and do what I can to get off this poison.

  • Mike February 5, 2016, 3:47 am

    Been on 800 for about 8 years went from 800 to 600 then down to 400 all within a month. I’ve been sick and up for days. I want to take one to feel better but… Ugh.

  • Rebecca Davidson February 2, 2016, 3:25 pm

    Day 4 of cutting down from 50mg to 38.5. Really small dose and really small reduction I know! Unbelievable how bad I feel. Tearful, anxious, brain fog. I really feel for anybody trying to cut down from 800. How is that possible?

  • Joanna January 31, 2016, 9:02 pm

    Hi. I’ve read a lot about withdrawal symptoms from both quetiapine (for me it was prescribed for bipolar type 2 and insomnia) and Lyrica (for me, fibromyalgia.) I am actually tapering off both of these drugs. I was a wreck last February (2015) and as I ordinarily would have researched the side effects, I was too depressed and anxious to do so.

    I am trying to get off quetiapine due to the weight gain. I used to weigh 134, now I am at 158. No matter how much I exercise, how little I eat (I eat healthfully and have done so for decades), I cannot lose the weight. It is due, in my opinion, to a decreased metabolism. I spoke with my psych person last Friday and we made a plan to half my dose, 300 milligrams to 150 milligrams for five days, then 50 milligrams for five days.

    This seems like a short taper to me, but I am giving it a go. So far, I am experiencing: Nausea, stomach cramps, diarrhea, anxiety, and shakiness. If it becomes severe, I will increase the dosage and try to taper more slowly. This drug is addictive, in my opinion. I hate what it has done to me for the most part, but it temporarily helped the insomnia immensely.

    I recently went back to getting non-restorative sleep, so I see quetiapine as useless other than the fact that it may be helping the bipolar type 2, though I am also on 300 milligrams of Lamictal for the bipolar 2. Do any of you have both fibromyalgia and bipolar 2, insomnia as well? I hope all of us can find the treatments that work for our particular health issues. It has been very helpful for me to read your comments.

  • Anne mitchell January 27, 2016, 1:42 pm

    I have been taking quetiapine for over a year, stopped taking it 3 weeks ago. I am having headaches every day and feeling nauseous also feeling anxious. I am sorry I ever started taking this drug but I am glad I have stopped taking it. Good luck to everyone coming off it and hang in there.

    • Joanna February 1, 2016, 5:53 pm

      Hi Anne. May I ask if you tapered off the quetiapine/Seroquel and if so for how long and for the dosage you took from each time you lowered your dose? Thank you.

  • Marilyn January 26, 2016, 5:51 pm

    I have been totally off Seroquel for just a few days. I weaned off. I itch all over. Am having trouble sleeping and feel anxious. I could cry at the drop of a hat. It is hard to work. I can’t seem to get anything done. My focus is off. But the side effects of this nasty little drug are scary. So I talked with my Doctor and we decided to stop the Seroquel. I’m glad I found this site. I know I am not alone.

  • Lakeisha January 26, 2016, 5:43 pm

    I was on Zoloft, lamictal, seroquel, and trazodone. My liver said no, my enzyme levels went through the roof. So I was stripped from these meds 2 weeks ago. I was only on them for 3 weeks. The seroquel made me feel like a zombie. I couldn’t drive and felt very foggy all the time. Now that I am off of seroquel I feel more alert, however my brain feels weird like there is a heartbeat in it.

    I see lines when I look up sometimes. I have anxiety and insomnia really bad. It doesn’t help that they misdiagnosed me at the psych I went to see. I am glad I’m no longer on those meds I feel better mentally and am getting more sleep. Although I need the trazadone to sleep I feel better about everything. I am driving now and doing what I need to day by day and feel aware not being on the seroquel.

    I just had a baby and have just been diagnosed with PPD and insomnia and have a new psych I go to that discovered I was misdiagnosed with bipolar PTSD along with ppd. I am getting happier everyday and feeling better. Just can’t wait for the withdrawal of the seroquel to subside.

  • Diane January 20, 2016, 5:03 am

    I have been on Seroquel for almost 25 years I think at 800-1200mg dosage per day. Getting off of it has been one of the hardest things I have ever done. Physically I have been off two weeks with a three week taper and experienced extreme nausea, fatigue and now insomnia. I had what I thought were the worst flu like symptoms Ive ever had the past two weeks. I haven’t had any mental effects yet but I suspect they are coming.

    I think Ill watch myself carefully for depression. I am a manic bipolar but Seroquel’s scary long term effects like diabetes and dementia scared the daylights out of me. I’m 46 and have been on this drug almost 1/2 of my life. I did notice that my sense of smell and auditory sounds have been bugging the crap out of me too. All I can say is drink a ton of water while coming off of it and get as much rest as you can to keep your strength up.

    For the nausea I ate Jello and nibbled on crackers for two weeks. My doc prescribed some nausea meds and that helped tremendously. Good luck everyone. I wanted to add that I NEVER want to be on a drug again that controls my life like this did. The withdrawals are so bad and the not taking it runs my life. NEVER again will this happen.

    • Diane February 10, 2016, 11:44 am

      UPDATE 02.10.16 – POST-SEROQUEL 5 WEEKS – Still experiencing withdrawals from this med. Main symptoms are extreme hypersalivation, severe headaches and slow motor skills. I’m shocked that being off of it this long and still these severe withdrawals. I was on 800-1200 mg consistently. I’m not sure when my neurotransmitters will go back to normal but am faithfully taking Lithium and Abilify hoping to stave off an episode. I am really bothered by the mouth watering. Does anyone know why this is happening?

      • c.c. June 24, 2016, 12:10 am

        Quetiapine causes hypersalivation (see dental journals.) Probably Abilify does, too. Withdrawal sometimes mimics the side effects of the drug.

  • Karen January 18, 2016, 8:09 pm

    For starters I will say that I was never supposed to be on this medication. My psychiatrist misdiagnosed me with bipolar disorder and would increase the dosage of the seroquel when I would explain that I felt sick being on it and did not help with my already ruined sleep cycle. My heart rate was always alarmingly fast which always made me nervous and my agitation was at an all time high. I truly wonder if there was anything that that drug did that did me any good.

    I have been cold turkey for the best three days and have been throwing up constantly and haven’t slept. I sweat through at least two outfits a day and have an absurdly runny nose that never stops even though I do not have a cold and am not sick. If anyone recommends this medication to you… Please research alternatives. If this works for you then I’m glad but for those of you who are also struggling I wish you luck!! Hang in there.

  • Brian January 18, 2016, 6:09 am

    I’ve been on seroquel for about 8 years. 600 mgs a night. I have no choice but to stop more or less cold turkey. I’m scared. Is there any useful advice or anything I might be able to do?

  • Chris January 17, 2016, 6:39 pm

    I have been on Seroquel XR and then Seroquel for 4 years and have just tapered off. My first night without was 3 days ago and it has been awful, vomiting, cannot keep any food down, barely sleeping despite taking 60mg of Serepax. I am itchy all over and it’s not easing up. I have been concerned about this medication for a long time, so it was my choice to cease, and despite doing it gradually, it is an awful experience.

  • Robert January 16, 2016, 5:55 pm

    Holy Moly, I just ran out yesterday and I dreamed I was hanging out with Scarface! LOL. I was on 800mg nightly, but due to issues I cannot control, I ran out of meds, and will not be refilled till Feb 3rd in 15 days. I am feeling very bad and was up every hour checking the clock and only an hour have passed at a time. I’m debating major issues, and my smarts are not coming back. I was 144 IQ… but while on this med, my IQ was tested at 98… according to the college I tried to attend. I will try and finish this comment later, gotta run to the restroom…

  • Cathy January 16, 2016, 12:51 am

    I’ve been on 100 XR and 100 regular mg for at least 5 years, I ran out and have been so so sick! Can’t sleep, bad anxiety, sweating awful, in fact hot cold hot cold and throwing up! I thought I was just sick, but now I’m sure it’s withdrawal. Thank God I just took my dose and hoping to sleep and feel better tomorrow! I never knew you could have withdrawal symptoms!

  • Brianna January 14, 2016, 7:00 am

    Hi guys, Was on seroquel 100mg in addition to lexapro for depression/mild bipolar for 3 years. I knew I’d put on weight but in the lead up to my wedding hopped on the scales in desperation. Turns out I’d put on 20kgs in that time which is the heaviest I’ve ever been by a long way. I’m 37 and am a bit of a yo yo weight wise, but when I put my mind to it I’ve always been good at losing weight in a healthy way.

    But when the scales have barely been moving for weeks upon end (1000cals plus gym 5 x a week) decided there was something more to it. You guessed it, the seroquel strikes again! So, now with only 8 weeks until my wedding, I’ve gone cold turkey. I’m actually really pleased to say that I’m doing well. Sleep has obviously been a struggle, but I’ve been using herbal supplements and tea, which has helped.

    Have had waves of nausea, a headache here and there and now feel like I have a cold coming on. Nearly five days seroquel free and I’m doing good! Maybe a kilo or so lost but will see how we are looking next week. I’m really angered to read the side effects of this drug and am disappointed that a much respected psych put me on it and it has jeopardized my health.

    My GP also told me I MUST be off it before falling pregnant which I didn’t even know… Anyway, good luck everyone. I hope your withdrawals are more like mine than others!

  • Jackie January 10, 2016, 1:24 am

    Update on my status: It has now been 1 full month of halving my dose from 300 to 150 mg. I no loner have mild nausea. I still have a bit of insomnia, but since I have been going to the gym regularly (4 days a week) I have noticed I sleep better and the insomnia is not as bad. My workout routine involves 45-55 min of elliptical time with my incline at 10-12 and resistance of 7-9.

    I then do a battle rope workout that I found online, then a squat/lunge workout (doing 45 seconds to 1 full min of each). If I don’t have time for that much at the gym, I do a 1 mile run as fast as I can, and as many 100 yard sprints as I can manage. I truly feel this has helped me sleep. I know exercise is suppose to release certain endorphins.

    I have to wonder if this release of endorphins my body is doing is some how counter acting the withdrawal symptoms. I plan to stay on 150 mg for another month before attempting to go down. I have not had any other withdrawls symptoms as of this time. Will update again in one month! Good luck everyone!

  • Mike January 7, 2016, 3:47 am

    I took 800mg for 7 years. I’m on 600 now in a few weeks I’ll go down to 400. I’ve been having a lot of withdrawal symptoms.

  • Yasmeen January 5, 2016, 4:00 pm

    I was on seroquel 125mg and cipralex 20mg I quit both of these drugs cold turkey 2months ago. I had been only 3months on seroquel and 4 years on cipralex. I did feel groggy and dizzy but it wasn’t as bad as being on the meds and feeling totally disconnected from life itself. I must add though that I am seeing a professional therapist that does DBT therapy and I couldn’t do this without him.

    Dialectical behavior therapy (DBT) treats at the level that no medications can and gives you a clear path to a healthier more balanced and satisfying lifestyle. I strongly suggest to anyone stopping medications to replace it with some form of therapy because I feel if you do not the reasons you started taking the meds in the first place are still there inside and will only come back out again…

    Whether it’s seeing a sleep professional, life coach or any professional who deals hands on with what is really bothering you and assists in your wellbeing. Hope this helps. Wishing you all success in your journeys. 😊

  • Sherina December 30, 2015, 3:46 pm

    I haven’t seen any comments posted in a while so hopefully someone sees this and can give advice. So I’ve been on Seroquel for 3-4months. Last month on only 12mg or so (shaving off pieces with knife so not sure of exact dosage). Anyways I was sweating so bad last night although it was cold in the house. Couldn’t fall asleep so I had to take .25 of Klonopin which is a small dose but a drug nonetheless which makes me very unhappy. Taking Lunesta 3 mg as well. Plan is to come of off Seroquel first and foremost. I’m trying to taper slowly but BC I’ve been on it for a short period of time, I’m hoping I don’t have any withdrawals or mild ones.

  • ByrdMom December 30, 2015, 3:27 pm

    I have been taking Seroquel for 3years @ 200 mg for depression and sleep disorder. A doctor gave it to me because my anti-depressent was not enough to help me sleep. I gained 35 lbs the first year, craved sugar and slept way too much. Three months ago, I cut it down to 100 with no issues. I can actually drive to work fully awake, so sad! I am now down to 25 mg.

    I still have times of mental fog, from the withdrawal, but I am determined to get off this tranquilizer. I am staying very aware of any returning depression, and so far so good. Seroquel reminds me of Xanax, but on overdrive. It dumbs your thought, and one day it’s three years later and you can’t remember what transpired.

  • Shannon December 30, 2015, 4:04 am

    This website scared the crap out of me. I had been taking seroquel 600mg for about a year. I cut back to 400 for a couple months because I was too restless in the night. Then I cut back to 200 because I still was having restless legs. My doc said I could stop taking it but I should taper over time. I decided to just stop “cold turkey” because I was worried about weight gain.

    Honestly, I hope this is able to help someone, but I had only two effects after stopping it. I had chills, and my stomach was a LITTLE iffy. Both effects lasted about a week. I never threw up. I had mild diarrhea. Now that I am not taking it I am sleeping better and feeling better over all. So sorry so many of you had to go through so much hell.

    • BeenthereDonethat July 14, 2016, 10:27 pm

      It’s really hard to believe you, TBH. You’re one out of hundreds with minimal side effects. Do you work for the company that makes Seroquel? Having all this bad press here could really lose them millions of dollars.

  • trish December 30, 2015, 1:04 am

    I wish I had done more research before starting this medication. I’ve been prescribed two years and I don’t even know who I am anymore. I seclude myself. I tried tapering and then cold turkey. I thought I was having a heart attack, along with sweats, calm one minute and just batsh*t crazy the next. Long story short I’m stuck on this med that does more harm than good to me.

  • Brenda December 29, 2015, 5:56 pm

    I was on 200mg for 8 years, for bipolar disorder, side effects worsened and increased weight and cholesterol. Started to taper off, down to 150mg for a couple of weeks, 100mg for 4 weeks, and 75mg for 4 weeks. Withdrawal symptoms included: nausea, flu symptoms, sweating, but getting there. Aiming to reduce to 50mg in a couple of weeks, if all goes well I will wait a couple of months and try 25mg.

    It seems from what I have read that the lower doses cause worse withdrawal effects, so will see how it goes. The main things that have helped are exercise (gardening), support from family and knitting (helps to calm me down). Hoping to manage without seroquel, making plans to deal with problems so I can cope as well as possible.

  • Netta December 27, 2015, 4:30 pm

    Hi Sophie. Good to hear that the quetiapine works for you. It did for me too in the short term. Long term it has caused some terrible physical problems. The experience of side effects, and withdrawal symptoms is not the same as being opposed to psych meds. I am not opposed to taking drugs that work, and that do not cause serious side effects. Of course, all drugs may cause side effects.

    Neuroleptics however, have some pretty awful (well documented) problems, including brain shrinkage, metabolic and heart problems. It is possible to recover from mental health problems without the use of psychotropic medication, though not easy! I got really tired of being told by mental health professionals that I would never recover, and would have to stay on medication for life.

    Choosing to come off of medications can earn individuals another label on top of the original one…troublesome and non compliant. Even some cancer patients have the hope that they might one day recover! In my case, and I suspect in many other people’s cases, drugs made things worse. Simple. I do not blame the psychiatrists who gave me the drugs. I am not angry. They did what they thought was best, based on what they have been taught. I made an informed choice to take the drugs knowing full well what the likely possible side effects were.

    At the time the drugs seemed a better option to the illness itself. I was not quite prepared for the full impact of the side effects, which only got worse over time. I did however feel really angry when my experiences of the side effects were dismissed, or blamed on my bipolar illness. There is no support in the UK for people who wish to come off drugs and find other ways to deal with their experiences of mental illness. And that is a great pity.

    There is absolutely no evidence to prove that mental illness is caused by a chemical imbalance, and very little evidence that the long term use of drugs does anything very useful. There is quite a bit of evidence that they actually do more harm than good. No, I don’t blame the psychiatric profession. I blame myself in part for believing everything I was told without doing too much of my own research. I wanted to feel better and doctors wanted me to feel better.

    Why wouldn’t they? It’s easy to swallow a pill and hope the pain will all go away, not so easy in reality because human beings are just too complex. Personally (and I really do speak for myself here!) I unconsciously colluded with my doctors, and sometimes wonder if they unconsciously colluded with me. Maybe psychiatrist’s feel a certain amount of helplessness and feelings of impotence when dealing with the mentally ill. It isn’t an easy illness to treat is it?

    It’s not like orthopaedic surgery where one has X-rays, sees the broken or damage bone, and fixes it. X-rays do not show up mental illness. Diagnosis of a mental illness is based purely on talking to the patient, and observations. Different doctors may see different things. Often an individual can end up with more than one diagnosis!

  • Sophie December 25, 2015, 10:54 pm

    I thought I should add that I do pretty well on Seroquel, I’m bipolar and it helps me to sleep but I am dependent on it. It’s Christmas Day and I’m not sure I’ll get a refill. I actually have gone through withdrawal within one day of not taking it before. I personally can’t read all these replies because of course I’m not the same as others and many people are medication resistant and their entire lives can be screwed as a result. I feel better on seroquel and lithium with small amounts of Klonopin. It changed my life. There’s always going be someone opposed to psyche meds: Communicate with your doctor. Not strangers on a website.

    • c.c. June 24, 2016, 12:04 am

      These comments tell you that doctors, especially psychiatrists don’t listen and don’t care. If yours does you are lucky. The comments of patients can be much more useful than a physician’s advice. Of course, we should all find good physicians if we can. I have not been so lucky in the past five years after thirty-five years of good care. But I have never met a psychiatrist who didn’t cause me harm in one way or another. Now I have a good lawyer.

  • Kayla December 24, 2015, 6:41 pm

    I am 15 and have been on seroquel for almost a year now. I take it for insomnia. I was on the dosage 250 mg. Recently, I was discharged from the doctoral place that was prescribing my meds due to not showing up to therapy appointments and not showing up to see my psychologist (yeah I know my fault). It has only been 48 hours and since not being on seroquel, I have had terrible withdrawal…

    I have not slept not ONCE in these 48 hours, I’m shaky, extremely nauseas and the headaches are out of this world. I sweat a lot even when I have all the windows open in my room. The withdrawals from this drug is seriously unbearable. I asked my mom to go get me the sleeping pills from Rite Aid or Walmart or whatever convenient store, but I’m afraid it wont have the same effect on my sleeping as the seroquel did…

  • Gemma December 23, 2015, 12:46 pm

    I took quetiapine for 11 months. Started tapering off a few weeks ago, at my psychiatrists suggestion. now nil. Mostly took 100mg every night. At the beginning I also used small amounts – 5-25mg as breakthrough medication. Also changed from venlafaxine (which was hell) to fluoxetine which has been good. The quetiapine helped a lot. I had drug & trauma induced psychosis, severe depression and anxiety. Depression since age 8.

    The psychosis is long gone, depression & anxiety markedly improved. I have been gradually feeling worse as I have cut down my dose. I am so thankful to have found this site. I had forgotten entirely to check out the withdrawal symptoms. I was expecting the insomnia, but not the teariness, mood swings, anxiety, depression etc. Such a relief to know what’s going on. Much thanks to the writer & others who commented.

  • Jackie December 21, 2015, 5:30 pm

    I have suffered from insomnia since I tapered down from 300 mg to 150 mg. I am on week two. Something that has helped me with the insomnia is going to the gym and exercising before bed sometime. After my workout I am exhausted and my body is exhausted. I have yet to have any other withdrawal symptoms except some minor nausea and not feeling hungry. As I continue with tapering off I will update my symptoms. I am truly praying that this will be the worst of it.

    • Netta December 24, 2015, 10:48 am

      Hi Jackie. Well-done in dropping your dose. Don’t be surprised if upon getting down to a very low dose you start to feel awful. It isn’t until one gets down to 50 or 25 mg that things become really difficult. particularly as far as sleep is concerned. At low doses quetiapine acts as an antihistamine (which is helps with sleep).

      I a found reducing from 400 – to 100 mg relatively easy and was lulled into a false sense of security. I stopped completely a week ago, and suffered horrendous insomnia. I therefore went back onto 25 mg, and then 50 mg when this didn’t work. The trick is (I think!) to take it really slow, and not beat yourself up if things don’t go as planned initially. Neuroleptics are a disaster as far as withdrawals are concerned…they completely alter the chemistry of the brain.

      It will therefore take time, patience, and nutrients in order to eventually heal. I really do firmly believe that I have recovered much quicker, and with fewer psychological issues because I have taken (and continue to take) important supplements. There is quite a bit of research into supplementation and brain recovery. Good luck and healing to all of you out there.

  • Netta December 14, 2015, 1:59 pm

    I should also say that I previously tried coming off all drugs cold turkey about two years ago. This was the biggest mistake ever! I quite literally did not sleep for about three weeks…I went completely mad! I ended up going to GP and begging for something to knock me out completely. I was suicidal, and in great physical pain. Really, I would advise anyone contemplating coming off neuroleptics to do slowly.

    I would also recommend at least taking a good multi vit, B complex and fish oils, but that’s just me. Unfortunately psychiatrists are not very helpful (or knowledgeable) in my opinion about the appalling withdrawal syndromes from these drugs. They also have the tendency to downplay the side effects, and blame every symptom on the original diagnosis.

    If the medications actually worked more people would take them! They might possibly workin the short term, but long term they are devastating. In fact, I sometimes wonder who is more deluded, patients or the medical profession!

  • Netta December 13, 2015, 8:24 pm

    I have been on Lithium and quetiapine for over ten years. I am now off all psychotropic drugs! Quetiapine caused me to have chronic seething depression, lethargy and a complete lack of joy and creativity. Also caused some hellish physicals symptoms (such as muscle stiffness). All side effects were completely dismissed by psychiatrists.

    In the end I got totally fed up of my complaints being ignored, and took myself off all drugs. This time I did it slowly, and also now take several helpful supplements. I have felt a bit sick, horribly itchy, and am experiencing insomnia, but overall, withdrawal this time is not too bad. I believe the supplements have been helpful. Plus I am no longer in a stressful job,and can be relaxed about not sleeping.

    I do sometimes take an antihistamine for sleep and itching. I have no intention of ever going back on these ‘dirty’ drugs, they are worse than the illness (Bipolar).

  • Cris December 7, 2015, 3:46 pm

    Here’s my story – In 2007, while in university, I was having a really difficult time and two separate psychiatrists diagnosed me with Bipolar 2. I was subsequently put on 300mg of Seroquel immediately. KFred, I empathize with everything you’re saying – although the suffering I was going through prior to Seroquel was clearly not “me”, I don’t think I have ever been myself again since that day in 2007.

    Over the years, simply because of the weight gain and extreme lethargy I experience from this drug, I slowly went down to 200mg and then to 100mg. If I ever missed a single dose for any reason I went through the full spectrum of withdrawal; vomiting, nausea, dizziness, INSOMNIA, anxiety etc. Naturally this made me extremely nervous to stop taking Seroquel, which has been my intention for the last year. I’ve finally recognized, through seeing GOOD doctors (so rare we find these, right?) and psychiatrists that take the time to get to know me, that Seroquel is not for me and it probably never was.

    One especially terrible psychiatrist, who no longer gets referrals because of his reputation, told me I could just go off cold turkey because the withdrawal symptoms would be the same as tapering off. I cannot tell you how dangerous it is to just go off medication cold turkey. Almost no physician of any sort of would recommend it, nor do I. Because I tapered off Seroquel, my withdrawal has been less severe so far.

    Mind you, I am on my last three days of taking 25mg and then I’m stopping, but what I’ve noticed the most is the insomnia. I am lucky to get around 4 hours of sleep right now. I also feel restless and agitated, but really, this is nothing compared to the debilitating withdrawal symptoms I experienced when I missed a complete dose altogether. Now, I’m not a doctor (and I don’t play one on TV), but my recommendation is to taper off Seroquel for the best results, and to never quit anything cold turkey.

    I wish the best of luck to everyone who is experiencing withdrawal symptoms from this horrible drug. I hope mine doesn’t get worse, but it’s comforting to know that there are many others out there experiencing this, so I thank you all for sharing.

  • Michael December 7, 2015, 5:03 am

    My taper experience + short story and background. Please do not quit abruptly. All of these people reporting major withdrawal symptoms after fast tapers or abruptly stopping, I am so sorry, I empathize with you. You must move off these powerful medications slowly.

    After some very stressful times in my life, I developed psychosis. Gradually through constant stresses I had break downs, became paranoid, and slowly delusions would become strong enough to get me to a meeting with a psychiatrist. A compassionate, nice Dr. Who did not want to overmedicate me. Mind you, my family did not take me into a psych hospital even though I was having horrible trouble. I went to a psychiatrist after 3 days of waiting, sleepless nights, and really worrying my mother. My mother whose care and compassion is a big part of why I’m recovering.

    Intervention: I had a terrible experience with risperidone (risperdal generic), taking 1MG morning and night. I was switched to seroquel, 50mg at bed time along with 600 mg of lithium. (300 twice a day). Low dose for a schizoaffective diagnosis. My psychiatrists opinion: If I’m having any positive symptom associated with mental illness; auditory hallucination, racing thoughts, etc. then I should pop an extra 25mg of seroquel. She used the same strategy when I started risperidone, which caused the worst night of my life, in which the psychological effects from the drug interactions were terrible.

    I never did take more Seroquel, even if I had a psychotic symptom. After some time, the delusions, strong visual hallucinations and really terrible thoughts cleared up. After taking seroquel and lithium for less then 6 months I decided to gradually taper. After tapering off lithium, many psychotic symptoms, simply went away. Things that would happen to me while taking both were racing thoughts, very slight difficulty reading. Sometimes words would appear differently then they were (never had dyslexia or that problem before psychosis), and very slight auditory hallucinations (very rarely distinguishable).

    It took me 2.5 moths to taper off seroquel completely. I am on day 9. I experienced twitches for days after taking it in my legs and around my body, horrible, and I mean horrible itching for approximately a week. Difficulty sleeping. everything but the sleep has cleared up for me now. What about my mental health? I cycle, that helps. I use methods to relax, massage, working, spending time with friends and family helps.

    I continue to have light psychotic symptoms, and fear that I may live this way for a long time. I just never want to be where I was in my experience of first time psychosis. Hope this helps any of you. There’s some I left out, but it’s the first post I’ve ever made about my experience anywhere.

  • KFred December 1, 2015, 4:56 pm

    I’ve been on 800mg of Seroquel XR for 8 years for Bipolar and treatment resistant depression. I have never been “me” since going on it at such a high dose but it was keeping me alive and somewhat functional until I recently had a manic episode and crashed. I went in-patient in hopes of coming off of it after trying out-patient 4 times this year.

    2 & 1/2 weeks ago The hospital Dr put me on REXULTI and cold turkeyed me off of the Seroquel XR. I’ve had the very restless sleep, vivid dreams, stiff joints, messed up vision, smaller appetite and restlessness. I do have to say though the REXULTI has been great so far (knock on wood) and I have lost 12 pounds since quitting the Seroquel XR. The worst side effect has to be the sleep problems.

  • Horrible Pain November 30, 2015, 5:50 pm

    I started tapering of in march after 5 years of using up to 800 mg seroquel. In the beginning everything was okay. I mean, I experienced flu like symptoms and trouble sleeping but I was doing a lot of walking at the time and felt really good. Often I was walking for 2 or 3 hours a day. I got down to 500 mg. Then my body just shut down. I became stiff in my whole body with horrible cramps and spasms.

    I got extreme pain in my feet and my body was constantly shaking. Now I’m down to 225 and are still experiencing the stiffness pain shaking and muscle weakness on a daily basis. The psychiatrists don’t know what we go through. That’s for sure. My muscles has wasted away. I don’t recognize my feet and arms anymore. I have two lumps. One on each upper leg which just appeared one day and have cramps in my whole body.

    The lumps are probably stemming from the cramps. I have trouble moving my head and my face is stiff. I go to a physiotherapist every week and even though it helps a little. Its not helping much. Seroquel has ruined my life. Last week in tapered 25 mg. the week before 75. The 75 went okay but since Friday its been worse than ever. I can’t even wear clothes because the skin is so sore and my muscles continue to waste away.

    I live with pain 24/7 and it feel like it will never pass. I also have trouble swallowing along with burning in my stomach and chest pains. I’m so tired of this.

  • Jennifer November 27, 2015, 12:10 am

    I’ve been taking 25mg for over 10 years for sleep. I’ve stopped cold turkey for 2 weeks now and have been feeling on the verge of the flu and am having crying outburst. I’m also experiencing the itching the last couple of days. Can anyone else relate that’s been on a low dosage? I so want to be drug free.

  • John November 26, 2015, 4:06 pm

    I was on Seroquel 400mg for a few months. I went down to 300mg…some nausea but that’s all. Then down to 200 mg same thing. Then down to 100 and then 50mg and then I quit cold turkey 3 days ago. So far I have had few withdrawal symptoms. I can still sleep using Melatonin. My seep is better but not as long as on the Seroquel. The only other symptom so far has been a bit of irritability and some itching. So far so good. I wish all of you the best of luck and a smooth withdrawal.

  • phyllis November 23, 2015, 1:44 am

    I .was diagnosed bipolar and am on lithium and Seroquel. After a few months of taking 300mg of Seroquel I gained about 25 lbs. I joined a gym, went for walks, ate less and not a lb came off! My clothes don’t fit and I feel disgusted with myself. I talked to my psychiatrist and we made a plan for me to taper off Seroquel slowly. Thankfully, I chose not to go cold turkey and just 3 nights ago I am off Seroquel.

    It’s been a little rough getting a good night’s sleep – and one night I didn’t sleep at all…but I’m taking one day at a time and am committed to staying off this drug. I’m taking an OTC sleep med – Unisom for now to help me sleep but plan to get off this as well. I’m eager to lose this weight and pray that I’ll start to see the lbs. come off soon. My advice is to taper off so you don’t have withdrawals. Also, don’t give up as others are hanging in there and can give you support.

  • dymond November 22, 2015, 4:59 pm

    All I can say is- wow! I have been on and off this med for over a decade to help with managing PTSD related conditions. I am finding, now that I am older, tapering off is hellacious. So glad I found this page! It used to be I could taper off easily, but this last round I have been on for two years 25 mg nightly and up to 100 mg a day if my system is flooded and I am processing particularly intense things. I thought to come online re: what I have been feeling tapering to 12.5 mg. Withdrawal…

  • Angela November 20, 2015, 9:12 am

    Eye pain is so bad, drives me nuts… Experiencing nausea and dizziness not so bad, taking ginger tea all day, helps a lot. I’m tapering the dosage. If I knew all the bad side effects of Seroquel XR I wouldn’t take it. Such a bad time that no matter how I feel today is. Nothing compared how I felt when I was taking it. Totally worth it to get it out of my system.

  • Howard November 18, 2015, 11:52 pm

    During the course of 2010 I became increasingly ill with an, as of yet, undiagnosed illness. Late August of that same year I had my first “smell” hallucination, which began coinciding with every bout of digestive illness from that point forward. Eventually my Gastroenterologist sent me to a counselor who sent me to a psychiatrist who put me on 50mgs of the extended release version and some amount of Lexipro (an anti-depressant).

    Seeing as I wasn’t depressed, I did not take the Lexipro, but did start in on the Seroquel (10/2013). Immediately, my Parosmia (smell hallucinations) went away. In mid 2013 I began suffering from debilitating muscle exhaustion and fatigue… which continues unresolved… while always increasing in severity. Not knowing if my Seroquel was contributing to the physical weakness, I decided to stop taking the drug.

    By January 2015 I cut down to 25mgs of Seroquel. Side effects were minimal, besides an occasionally odd feeling of fear (lasting no more than an hour at a time). After a week or so I seemed to adjust to the lower dose. In June of 2015 I cut my dose down to 12.5mgs. Within two days the Parosmia (smell hallucinations) came back. October of 2015 I cut down further, this time taking a quarter of a 25mg pill (approximately 6.25mgs). There weren’t any notable side effects this time.

    November 1st 2015: I stopped Seroquel completely. Sleep was harder to come by for the first few days. Also, I developed a sore throat and felt as though I was catching a cold. This flu-like symptom lasted for eleven days, but now seems to be on the wane this past week. The worst of the symptoms is related to my vision. Every day by early afternoon my eyes start failing me. They itch and burn and feel as though they are covered by a thin layer of sand.

    Eye drops don’t really help. And worse than that, my eyes are highly sensitive to any light source. Mostly I don a pair of sunglasses and/or wear a sleep mask. I suspect this may have something to do with the histamine blocking function inherent to Seroquel.

  • Jim November 18, 2015, 2:32 pm

    Hi, I was prescribed Sertraline and Seroquel for depression/psychosis just over a month ago. I was at 100mg Sertraline and 600mg Seroquel. I’m now being told that it’s not necessary for me to be on the Seroquel and i’ll be tapered off it. I went down to 300mg ok and have done 3 days at 150mg but have been getting ringing in my ears for about a week now. Does anyone know if the ringing might go?

    My doctor thinks it might do and is caused by the Seroquel. Struggling to sleep much at 150mg as well so not looking forward to reducing next week to 100mg then the week after to 50mg. I’m half tempted to just quit now and put up with the consequences as I haven’t been on it very long and figure the longer I stay on it the harder it will get.

  • T November 18, 2015, 3:45 am

    It has been over 6 months since I stopped taking seroquel. I had been taking 200 mg a day for 6 years! It was given to me at that dose because it was available in free samples. I have suffered from anxiety, excessive worrying for many years and despite the medications I’ve tried it’s never really changed. That’s why I started to believe that it’s therapy that I need instead of powerful drugs with unpleasant side effects.

    I still take wellbutrin daily, because I think it would be a mistake to come off both, plus I’m not experiencing adverse side effects from it. As for the withdrawal symptoms from stopping seroquel… I’ve had them all, and some are still present. The itching and severe nausea took months to subside as well as stomach problems. I’ve had a few night sweats and I struggled with constipation, gas and diarrhea. I took restoralax for one week to produce a proper bowel movement which got rid of the gas and helped me get back to normal.

    I also felt sick, tired, dizzy, and depressed… I cried a lot… And still do. More recently I started getting hives on my hands, legs and face, and seem to be experiencing many allergy symptoms. I don’t know if the two are related, but it caused me a considerable amount of stress. I started visiting my GP frequently insisting there is something wrong with me and that I must be dying, because I feel so awful all of the time.

    She has sent me for x-rays, scans and bloodwork to rule out other causes, and I appear to be physically healthy. She did however prescribe tecta for 8 weeks to help with the burning in my stomach. I still don’t sleep more than 4-5 hours a night, and that’s with using a sleep aid called immovane. Without it I can’t fall asleep, and if I happen to pass out from pure exhaustion, I won’t stay sleeping. I hope this helps anyone who wants to stop seroquel, or is going through the withdrawals. Reading this article and the comments saved me from feeling convinced that I was dying.

  • Stephanie November 17, 2015, 1:57 am

    I took a 14 day trial and had to quit cold turkey. $800 for a 30 day supply. I am feeling mild to severe nausea, headaches, appetite loss. No mood changes. My body did ache but thank God thats gone. I have thrown up. While I was on it. My depression was gone but I slept for 16 hours a day. So tired all the time. Now I have decreased sleep due to dizziness. It’s bearable. But I only tiered up to 300mg. And was only on it for 14 days. I hope these go away soon. However I am enjoying the manic. Haven’t had one in years.

  • Brian November 16, 2015, 4:28 pm

    Exercise and diet go along way in coping with any seroquel withdrawal symptoms…

    • BeenthereDonethat July 14, 2016, 8:57 pm

      LOL! Do you make this stuff? You can’t even function enough to get off the couch! It’s CONSTANT nausea! Who are you, and why would you say such a thing? Do you run a gym or something?

      • Anders November 18, 2016, 8:08 pm

        Exercise helps – know that it is tough to go to the gym. I do crossfit which is the only thing that get me started every morning. And yes I am on seroquel, and I do not own a gym…

  • Christina November 13, 2015, 8:38 pm

    Having no life and feeling old before my time. My energy is returning bit by bit and I do cry for no reason at times but its manageable as long as I come off it very slowly. No doubt my doctor would have me come off it quicker but I know best – she has not been taking it – I have. I was not psychotic, just anxious. It is used to keep us quiet and so we go away. My brain is now functioning better but I am still in a fog. I have 100mg to come off yet, but my goodness I am going to do it very slowly. These medical people do not know what they are prescribing – its a scandal.

  • Kelly November 13, 2015, 5:53 pm

    I stopped taking seroquel 2 weeks ago and added klonopin and Latuda at the same time. I was good for the first week, but wasn’t really hungry, itchy, had some headaches, and not getting much sleep, but still a few hours a night. A week after I started throwing up everything I ate, only sleeping maybe an hour a night and constant nausea. The klonopin and Latuda I think are helping with the other side effects, agitation, mood swings, etc. so I’m lucky it’s just the “flu like” stuff. P-doc said I can stay on .25 mg klonopin daily because it controls the anxiety stuff without the Xanax hangover since it has a longer 1/2 life.

  • Tivonah November 12, 2015, 6:40 pm

    I quit Seroquel after high dosages for over a year when I switched to Abilify. I had no withdrawal symptoms at all.

    • c.c. June 23, 2016, 11:52 pm

      Abilify is even worse than quetiapine, and it does the same thing. That is why you don’t have symptoms.

  • Ben November 11, 2015, 11:17 pm

    Been taking 450mg (3 x 150mg) since a manic episode in 2012. Over the last couple months I decided I want to wean off the stuff. It’s expensive ($100/month) and I was laid off (on the dole). I think it might me making me more tired and cranky than I want to be. I had asked my doc (about a year ago) when I could start going off. He wanted to wait another 6 months.

    I waited 6 months but then decided to go it alone. He’s hard to get an appointment with anyway. For a month I went down to 2 pills (300mg). For another couple months I went to 1 pill (150mg). I didn’t experience any problems so when this latest refill ran out yesterday I figured I’d be fine. I didn’t sleep a wink. Called in sick to work. Spent the whole day feeling tingles all over and feeling swampy (like I have been sweating lightly all night and day).

    I decided to call in a refill so I can make it to work tomorrow. I had NO IDEA people were taking as little as 25mg and having issues coming off. I was told that it takes 350mg for a “therapeutic dose” so I assumed that much less that that wouldn’t effect much of anything. I’m glad I found this page. I’m going to start breaking them in half for a month and then quarters. At that point I’ll be down to 25mg. Hopefully, after a month or so of that, I can stop.

    But this time I’ll make sure it’s on a long weekend or something. I had no idea it would be like this. What a nightmare. I guess I can’t be too mad. It (probably) kept me from going manic a number of times when life stuff wasn’t going so well (not working; wife left). But things are looking up! Woohoo!

  • Holly B November 3, 2015, 9:33 pm

    I am currently trying to taper down my high dose of Quetiapine. I’ve been on 600mg daily for at least 3 years. I now hate it, and I’m reducing very very slowly. I ran out once, over a long weekend and couldn’t get any so I had none for 3 nights and it was utter hell. I slept maybe 2 hours over the whole weekend and attempted to go to work on the Tuesday – ended up being driven home by my boss, crying, shaking, vomiting & delirious.

    I’ve genuinely never felt so unwell in my entire life as I did that day. I’m currently reducing by 25mg every couple of weeks which I think is probably quite slow(?) but I’m still suffering a number of withdrawal symptoms: sleep disruption, night sweats (changing my PJs twice a night as I wake up drenched), no appetite, dizziness, headaches, hypersensitivity to light/sound and more recently dissociation and detachment.

    (I’m worried about the possibility of psychosis as I’m having trouble grounding and differentiating between my vivid chaotic dreams (nightmares) and reality). I can’t believe how much it is affecting me, coming off this drug is a nightmare! I feel a bit scared that I will have to be on it forever if I can’t come off it. I’m reducing with support of a fantastic gp and having regular check ups so I’m pretty safe, but it’s very unpleasant. :(

  • gm86 November 3, 2015, 6:19 pm

    I have just tapered off quetiapine, I was on 450mg daily for 8 months, I have put on roughly 28lb and feel so unhealthy, my appetite was uncontrollable and I am so glad I am off this drug, it did its job in stopping symptoms of psychosis, but the side effects of the drug are horrible. I have only recently (a day ago) completely stopped taking it and am experiencing the nausea, but nothing else, let’s just see how I get on over the next month or so. Anyone on this drug who feel like the cons outweigh the pros, get advice and talk to your CPN or GP. Good luck to everybody coming off this drug! Stay strong and remember you are in control.

  • Christine November 3, 2015, 6:15 pm

    I’m doing cold turkey off 800 milligrams a night and ambien…after 8 years. It’s been 4 days. It’s not fun. I’m alternating between anger and extreme depression. Totally exhausted, sweating, and not sleeping. Hoping it gets better.

  • Julie November 2, 2015, 4:46 pm

    I went cold turkey about three weeks ago. I felt great when I got off the meds for the first week or so. I would just wake up at 6 everyday and not feel sleepy to go back to sleep. Today I started feeling a little more anxiety and nausea. I’m hoping this will subside as I’ve been exercising and just telling myself that this will pass. I gained about 50 pounds on Seroquel, had a high BP, and was borderline diabetic.

    I was more miserable with the weight gain on the Seroquel. I do feel better without it mostly because of the weight gain. I switched back to the drug I was on before Seroquel which was Wellbutrin. I’m not sure why I was put on Seroquel because it’s an antipsychotic and for bi-polar and I just suffer from depression and anxiety.

    I hope today was just not a good day and I won’t have these symptoms again tomorrow. I pray for everyone else who is going through this struggle. It is difficult and I hope everyone does better. Just take it one day at a time. Good luck and God bless.

  • Jane November 2, 2015, 12:50 pm

    Closing in on two and a half months off and my sleep is getting worse. I am terrified this poison has permanently destroyed my ability to sleep…I was up virtually all night again…feel horrendous. Beginning to lose all hope. :(

  • Tammy November 1, 2015, 1:05 pm

    I went cold turkey off seroquel two weeks ago, I have been nauseous for 12 of the 14 days. I would recommend tapering off it slowly, feels like I have the flu, but just nauseous. Oh and never take zopiclone either.

  • NeuroRu October 31, 2015, 11:45 pm

    I feel so validated reading all these experiences. I have been on between 50-300mg of seroquel for the last 15 years; originally was prescribed for bipolar disorder but I have mainly been using it for insomnia lately. The past 2 years it has been 50mg, so going off perhaps hasn’t been as bad as if I’d been on a higher dose. My withdrawal symptoms have been similar to others: insomnia, itching, tremor, mild psychosis (especially when I’m trying to sleep).

    One thing that has really helped me is taking Benadryl at night. This helps the itching and makes me a bit drowsy so maybe I’ll sleep a little better. Makes sense because seroquel at lower doses is mostly histamine blockade. Docs really shouldn’t be prescribing this stuff for sleep. I wish you all the best of luck getting off this drug.

  • Heather October 27, 2015, 5:38 pm

    I’ve quit seroquel recently cold turkey because of a mix up with refills. Needless to say the withdrawal is, like most of everyone else, an awful task. Mood swings, tired, nausea, body pains… Etc.. I hate it! Up… Down… Up… Down… I have bipolar disorder so I’m experiencing mixed mood. So I feel energized and tired. I want to do stuff but decide not to. Nooo motivation, racing thoughts… Anyway I’m glad I’m not the only one going through this.

  • Kristyn October 22, 2015, 1:47 pm

    I was diagnosed with bipolar type 2 and severe anxiety 2 and a half years ago. I was on seroquel for 2 and a half years and was on 800mgs a night (600mg normal and 200mg xr.) I’m also on 250 mg of lamotrogine (lamictal) and 1000 mgs of sodium valproate (epilum.) I gained around 15kgs from taking seroquel so the weight gain was getting me really depressed and had constant thoughts of losing weight in a very unhealthy way as I couldn’t lose the weight.

    I tapered off very quickly (my psychiatrist recommended to do it over weeks but I did it in less then a week) and the withdrawal symptoms have been so intense. I was on 100mg a week ago and went down to 50mgs over 4 days. I had to goto the city and my anxiety was as severe as it used to be. Constant nausea to the point where I was sick (the constant waves of sickness) and really bad body tremors (seroquel also was used for my anxiety.)

    I’ve been off seroquel for 3 days now and I’ve had 6 hours of broken sleep in 48 hours (I sleep for 7 or more hours per night and I LOVE my sleep.) The first night I didn’t sleep at all and ended up crashing at 11am and woke up at 1pm. Last night I didn’t get to sleep until 5.30-6 am and had broken sleep until 10am (surprisingly I haven’t felt foggy in the head I’ve just felt really alert.) The nausea coming off seroquel is so intense and crippling (not like anxiety sickness.)

    I feel sick from the moment I get up until I fall asleep. I’ve had intense kidney pains, my glands have been swollen, a sore throat and chest pains occasionally. I haven’t been eating much and I’ve lost 1.5-2 kgs in 2 days. The headaches are also quite intense also. I’m hoping these withdrawals will get better as the days go by. I definitely would NOT recommend quitting cold turkey as I read a blog about a girl who ended up in ICU and she was on 300mgs.

    Has anyone else been on a high dose for a long period of time and how long did the symptoms take to subside? Sorry this is a long comment but I hope that it helps you with understanding the feeling of quitting.

  • chris October 10, 2015, 4:41 am

    Without Seroquel I cannot sleep at all. I have been taking 1200 mg every night for 15 years. I do have bipolar as well. Several moths ago I reached in to the cabinet for my meds. I took out a bottle out that look identical to Seroquel the size and color were almost identical. For about 10 days and nights It became miserable I did not sleep at all just staring at the clock watching each minute go by.

    I kept taking more pills each night took about 6200mg tablets or so. I finalize after 10 days realized that I was taking 300mg of prescription strength Tylenol I would up having yellow eye so wen to doctor to check for liver damage. The bottom line is not sleeping at all w/o Seroquel. Any insight would be helpful. Thanks.

  • Lucie October 7, 2015, 1:01 am

    This is more a question: Do any of you, who have been completely off the Seroquel for 3 months still struggle? Two main things; insomnia and bouts of depression, crying, but feel better after I cry…

    • Jane October 9, 2015, 5:02 pm

      I’ve been off Seroquel for almost two entire months and am still struggling with insomnia and depression. Sometimes the sleep improves for a week or so – only to worsen the next week. The depression is almost constant. I think it just takes some people longer to recover from this stuff. I am also unable to lose the ten pounds I gained on it, but I am trying to be patient :(

  • Debra October 4, 2015, 6:39 am

    Hi, I am 54 and have been on Seroquel for 15 years. Due to having a heart attack 12 months ago I was advised to stop Seroquel. I have been tapering for over 12 months from 400 to now 50. It has been slow and sometimes I have tried to reduce and had to increase again for a while. I had to sit on 100 for a long time, probably 5 months but one month ago reduced to 75 and now to 50. At 50 I am experiencing symptoms similar to when I first started Seroquel.

    After taking it at night I develop retro amnesia and forget the hour prior to taking it. This happened when I first started. I don’t like it but I am still continuing. The only withdrawals I have experienced have really been nausea, sweating and after every reduction at least 2 incredibly bad nights with no sleep and agitation. But on the third night it seems to settle. I am not sure what will happen when I get to actually stopping it but so far I am succeeding.

  • Justine Freeman September 28, 2015, 6:18 am

    It’s true about coming off quetiapine. I was on 100mg for three years at bedtime for insomia, but quetiapine has Thiazepin compound in the molecular structure. Thiazepin is a strong antihistamine to prevent inflammation. I regret ever taking quetiapine, I had to stop due to many serious health complications. I stopped by reducing my doses over months down to maybe 10mg of quetiapine at bedtime which does nothing, but I’ve completely quit now and my head always feels like its on fire it’s called encephalitis or vasculitis which means chronic inflammation of the brain.

    My eyes stay bloodshot red. I have been rubbing castor oil topically on my stomach and liver and on my back for kidneys and doing cleansing homeopathic detox. Three cups of warm water as an enema flush helps too. Seroquil is a bad drug. Damages brain and harms eyes, I think about suicide more than ever. If I make it through this… I may write a book someday and even do foster care. Depression is real and oversleeping with seroquel will make it worse it will drain you. I am only 24 years old, female from Seattle. This drug has landed me in king county jail three separate times due to the aggression it pents up.

  • Bg September 23, 2015, 4:22 am

    So glad I’m not alone! I was on 200mg for 7 years and have been tapering off. 3 months later, I am down to 100mg and STILL feel awful! The nausea is unbearable! Posting this to see how long it takes for the nausea to go away? Any input is appreciated. Hoping I don’t have to deal with this forever :(

  • Felicia September 22, 2015, 8:26 pm

    I am almost one year off Seroquel completely. I was originally prescribed this med almost ten years ago as a sleep aid only. It took me over a year to taper myself off the drug. I attempted cold turkey from 300mg nightly to nothing and it was a disaster. I thought I was going to explode. I lasted three days then got back on, but I started taking just 150mg nightly. I would very slowly decrease my dosage, sometimes by as little as 10mg.

    I would reduce, then wait for side effects to subside, then reduce again. Sometimes it would take a few days, sometimes weeks and in a few cases a month or so for them to subside enough for me to feel ready to reduce again. Each time I reduced I had side effects, the worst was feeling like my heart was going to explode so I started taking 1mg of lorazepam if I was desperate.

    When I had successfully tapered to about 10mg nightly I started adding in melatonin nightly. Again, I continued to taper very very slowly. In addition to the melatonin I also added in an over the counter med similar to Tylenol Simply Sleep. I also worked on decreasing my dosage of lorazepam and now almost one year later I am free of both Sero and Lora. The side effects I still feel regularly are sluggishness, migraines, vision issues every once in a while and rapid heart beat in some situations.

    For the most part I’m happy with the outcome, better than being addicted to the Sero. My one piece of advice if I could only offer one is this: TAPER!!!! Good luck to all of you attempting to get off. It is worth it, just hang in there and go as slowly as you need to. It’s scary as hell realizing you are dependent on a drug, but completely possible to be free of it.

  • TONI (Australia) September 19, 2015, 1:55 am

    This is a great site for comments, and I first discovered it when I was in the final weeks of coming off Quetinpine, and began to wonder if feeling ill had anything to do with side effect so stopping the medication. Having stopped taking Quetiapine completely (as of 4 weeks ago) I agree wholeheartedly with K. Andrews, above. Don’t try to reduce your dose too quickly.

    My final 3 weeks of completely finishing with Quetiapine was half a 25 mg tablet every 3 days. I cut the dose by 1/2 a 25mg tablet (12.5 mg) over many months. Allowing your brain and body to adjust by reducing the dose slowly, and maintaining the new dose for at least 4 weeks, will reduce the side effects of coming off it completely. I still had side effects of nausea, itchiness, bad taste in my mouth & headaches.

    Insomnia is slowly improving, and I do take the occasional sleeping tablet (maybe once a week) to have a sleep deficit ‘catch up’. Have lost 6 kgs without any extra effort. You will get there, but treat your brain and body with kindness and do it slowly and gradually. Good luck to you all.

  • Steve September 19, 2015, 12:22 am

    I’ve been on Seroquel XR for a little over a year now. I started off at 50 mg, and my doctor gradually increased the dose to 300. At one point during that time, the dose went as high as 400, but the side effects were so unbearable that the dose was reduced back to 300. In the amount of time span that I’ve been on this medication, there have been some positive things out of it, like reduced anxiety.

    However, overall, I feel like there have been a lot more problems while on the drug, the biggest of which has been weight gain. I decided to cold turkey the Seroquel, and I’m now on day 3. Since stopping, there haven’t been any psychological changes (i.e. no worsening depression or anxiety). Instead, there have been grueling physical sensations. I have literally not slept at all the past 3 days, despite my best efforts.

    I’ve also never experienced this level of nausea before. If I stand up, it feels like the room is spinning, and I’ll have to take a moment to orient myself. I’ve also been sweating and just generally feeling like my body is warmer. I’m glad I found this site. It’s at least a little bit relieving knowing that there are others in the same shoes, and that these side effects are known to be caused by stopping. Even though its bad right now, I’m going to try to just tough it out.

  • K. Andrews September 16, 2015, 5:32 pm

    My experience with going down on Seroquel doseage is DO NOT GO TOO FAST. I tried dropping my dosage by one quarter for three weeks and it was agony all around, severe insomnia, severe itching, weird crawly feelings, bad headaches and migraines, brain fog, feeling unwell generally, severe anxiety, increasing depression. Finally I called my pharmacist and he advised me to increase my dosage up to what I had been taking, and then 2 weeks later to drop it by just 25 mg at a time for 2-4 weeks depending on how I was reacting to it.

    It has been MUCH easier since I followed my pharmacist’s advice. I am sleeping which helps me to feel better all around. Itchiness has subsided, brain fog is improved, anxiety has improved, less headaches, milder migraines. I have been told that this is not an easy medication to get off of…and going SLOW is KEY. My P-doc. as well as pharmacist are in agreement on this advice. Hope this helps someone else.

  • Sara September 7, 2015, 2:13 am

    AGE: 35. DOSE: 150mg. DURATION: 5 years. I’ve had to taper my withdrawal with only good ol’ Doc Internet for advice as I was having heart problems and couldn’t wait the 3 days to see my real life doctor. The nausea is the worst thing for me as I’m used to being in pain most of time (disability related), that said it’s certainly kicked it up a few notches!

    I’ve found ginger capsules help the nausea and strangely enough cayenne pepper helps my muscle spasms (?!). My sleep is patchy, but I’ve found catnip tea helps me drop off even if I’m still waking up every hour. I literally raided my larder for anything Doc’ Net came up with. This is day/night 3 at 75mg. Due to see the saw bones later today and hoping she doesn’t have a melt down. She’s rather fierce. Has anyone else noticed a decrease in fluid retention after cutting down?

  • Lucie Duquette September 3, 2015, 5:59 pm

    I am so grateful for this site, as I don’t know anyone else who is/was on this medication and it is so reassuring to know that I am not alone and to read everyone’s comments. My psychiatrist is not very helpful at all, in fact in her own words: “I only prescribe/control the medication part of your treatment and do not do therapy”, so I have to find someone to do CBT and pay extra money, also my GP doesn’t know (he treats colds and such), and that is why he had referred me to her.

    GP and even psychiatrist have not much training on medications and it effects at all, they just know what the pharmaceuticals companies are telling them. More education is necessary. I have had a lot of the withdrawal symptoms that you all mentioned and my psychiatrist (we almost had a fight about this) is adamant that there is NO side effects to stopping Seroquel, and if I feel bad/sick it is because my old symptoms (before medications) are coming back; which I highly doubt as I did not have this terrible itchiness before. Any comment/advice would help. Thank you.

    • BeenthereDonethat July 14, 2016, 8:27 pm

      Your psychiatrist is wrong. Nothing startling about that. I guess they just aren’t up to the job.

  • Nancy August 30, 2015, 3:57 pm

    My husband was on seroquel for 3 weeks at 100 mg to try and help him with insomnia. The seroquel caused such severe agitation and restlessness that the not sleeping grew much worse. The psychiatrist said to cold turkey it. We said yeah right we don’t think so. So he went from 100 mg to two nights of 50 mgs to two nights of 25 mgs.

    His withdrawal is severe even with: 1) only being on this med for three weeks 2) taking a relatively, I guess, low dose, and 3) tapering off of it possibly too quickly though’. I am so disappointed with the docs we’ve seen who throw pills at symptoms without looking at what is going on underneath that is causing the insomnia or anxiety or whatever it is. I hope my husband can hang in there through withdrawal. We do not want to go backwards.

  • Micah August 29, 2015, 10:15 am

    Hello – I am on my 3rd day do withdrawal from Seroquel. My prescription ran out and I cannot get refilled until Monday. Insomnia and throwing up are the main symptoms (3 hours of sleep in the last three days). No appetite. I did drink a couple beers hoping that it would help me sleep. No go. Did not make a dent in that wall of insomnia. No itching. Runny nose and sneezing, though.

  • Julie August 29, 2015, 5:24 am

    I’ve been on 25mg for about 8 months and as of 3 days am off. First day I had nausea second day I couldn’t sleep well as this is why I was taking the med. The third day I have extreme itchiness… anyone else? Funny my doctor said it’s not from the med… What I read I’ve had. Frustrating!

    • Amber June 21, 2016, 7:27 pm

      Hey Julie. I’m 5 days off 25mgs for the last 6 years and I’m so freaking itchy and I have the worst hay fever. So glad I found this thread because I thought I was having some kind of physical breakdown. I have been crying too but that’s not unusual for me so I didn’t really take much notice. Not sure when you posted this so I may be way late with my reply but I’m wondering how you are going?

  • Stephen August 26, 2015, 2:57 am

    I am trying to come off quetiapine after being on it for 9 years. I discussed this with my psychiatrist a number of months ago and after agreeing with her that it was the right time I reduced the dose over a few weeks. I found it hard to cope with the insomnia and decided to go back on just to cope with life. This is now the second time I’ve tried to come off and its been about 3 weeks now.

    The worst thing for me has been the insomnia (I’m writing this at 3:13am!) A few nights ago it was driving me so mad that I almost took a tablet to get me over. I don’t want to use it as a sleeping tablet. I thought it would be simple to come off but after reading this site it seems its going to be a lot harder than I thought.

    I am finding it difficult trying to keep working full time and with a young family sleep is always needed!! My concentration in work has not been great. I feel sluggish with very little energy and drive. I need to try and get some exercise but again its hard finding time. I have also been finding my stress levels have been high at times. Its hard to know whether it’s coming off the drug or just ‘normal’ working and family stress.

    To be honest I feel like I have been so unaware of how this and other drugs have been affecting me (I am on lithium for bi-polar disorder too). I have just accepted that I have to be on medication and not asked many questions. But now I’m starting to wonder what are the long term effects? Is the anxiety and depression I struggle with a result of the medication or is it ‘just me’? What are these drugs actually doing to my body?

    I studied counselling part time for 3 years and was also referred to a clinical psychologist for a year. Both seemed to help me take more responsibility for my thought life. I realised I could actually have some control over depression, anxiety and anger. I also went for regular Christian prayer ministry which really helped and I draw a lot of strength from my relationship with God.

    Now I just want to get off all my medication and leave the last 12 years behind- it seems that my whole life has been ruled by depression and anxiety and I’ve had enough! I want to start living rather than just ‘existing’ for the sake of my family as well as myself.

    In the meantime, if I could just get over this insomnia that would be half the battle! Even now I can feel my heart racing. Please pray for me. Please pray for sleep and rest. Thank you.

    • Joanna August 26, 2015, 3:56 pm

      Hello. I was put on quetiapine/Seroquel 150mg in 2002. My diagnosis was incorrect for starters. I am not schizophrenic. I do not have any symptoms for schizophrenia, and I never did. I believe that I was suffering from PTSD of sorts, but the “Stress” was ongoing and not something I could remove myself from. I am a victim of stalking. I took the medication at full dose (150mg) back then, because I was so unhappy at being stalked, I actually wanted to believe that a medication could convince me that it was in my imagination and it got me to sleep which meant I could escape the reality for a while.

      It was just a tranquilizer that shut me down and made the stalking easier for the stalker but not me. In hindsight, I truly know that had the psychiatrist recommended a short stay in hospital, with emphasis on rest, eating well and talking through my problem, I would not be here today, writing this. I just needed a jolly good cry and people to believe me and help me to come to terms with it and a miracle to help me rid myself of the pest. That help was not available.

      In fact, if I so much as mention “stalking” to a health care professional, they immediately think I need to increase my medications. I can not emphasize strongly enough, that health care professionals are blinded by the pharmaceutical companies to push medications on us. The trouble with this is that a short term fix becomes a life long dependency on a drug that has so many debilitating side effects.

      I have dealt with the stalking in my own way. I am an artist and I have done work to communicate it. It doesn’t take it away, because stalkers are sociopaths and very hard to rid ourselves of. Gradually over the years I have gotten my dose of the Quetiapine down to 50 mg. I will slowly but surely keep reducing it, unbeknownst to the psychiatrist, because in all honesty, asking them to help is ridiculous. I can not speak to them about it, because they simply can not get their heads around it, or even give me benefit of the doubt.

      I asked my psychiatrist today that “If every day of your life, someone hit you on the head and that resulted in a headache, would you just take an aspirin every day to get rid of the headache, or would you look for people to help you to stop that person from hitting you over the head?” She didn’t have much to say to that. I wish everyone who has found themselves on this page, because they too have been prescribed Quetiapine, every hope for a brighter future with great health and prosperity <3

      • Cate December 25, 2016, 12:18 am

        Joanna I am so sorry to hear about your stalking experience. I had an experience with psychopaths too which led to severe PTSD, medications for years (including seroquel) and now possibly permanent issues from them. It’s terrible how we are given drugs but not therapy! I hope you’re doing ok. Hugs.

    • Joanna August 26, 2015, 4:16 pm

      Stephen, I will pray for us all. I read your comment and I know exactly how you feel. It has brought me to tears, knowing that we have been given drugs that shut down all our joy to live, but make us just about able to function. I have been reading about what quetiapine does to our brain. It drastically reduces “dopamine” which is the hormone that our brain naturally produces and that hormone is associated with “reward motivated activity”.

      People with high levels of dopamine are usually creative types. However very high levels can cause mania. That is where Quetiapine comes in and why it is prescribed. The dopamine is what we are missing! We feel down and like we are just existing, because we are deprived of a feel good hormone. In place of dopamine, quetiapine makes our brain produce more pro lactin. That hormone fights off the dopamine. Pro lactin is high in pregnant women. We are all struggling with our weight because of high pro lactin levels, a direct result of quetiapine.

      I have written my own comment on this page too, which explains how I got in this position. I do agree that exercise helps us to feel better and with the weight and so does a healthy diet. However, I explained to my doctor that it feels like swimming against the tide. Like all the effort we put into staying fit seems unrewarded with the little amount of weight we lose. I will go back to the gym though, because that is at least something positive.

      Again I will pray for us all. God bless you and I hope you find a solution for your health and you get the wellness and happiness you deserve for yourself and your family. (That was the bit that made me cry – I too have a family and I sometimes feel like we are just existing). -Joanna

      • Stephen McClelland September 6, 2015, 6:38 am

        Thanks for this Joanna and your prayers. I will be praying for you and your family, that you find peace and joy in your life and the strength to overcome all the struggles of coming off quetiapine. Stephen.

    • Lucie September 7, 2015, 6:26 pm

      Stephen, a lot of what you wrote resonates with me. I often too wonder if it’s just me or the medications (I was on Seroquel for 11 years, psychiatrist started me at 365 mg to help with my depression and insomnia, and I have lowered the doses over all these years). The last two months I took none (I was at 25 mg) and insomnia, fatigue, feeling sick and itching, but like you the worst was the insomnia so I gave in and took 1/2 of 25 mg (cutting it); and I did this for the last 3 nights in a row but now I’m worried that I’ve gone backwards, I don’t want all my “hard” work of the last 2 months to be for nothing, so I am planning to either cut the pill in quarters or stop completely. Any thoughts? Thanks. You can also communicate through my e-mail if you wish: lmcgh7565[AT]yahoo.com. Good luck.

    • Lucie October 5, 2015, 1:39 am

      Hi Stephen, the insomnia is the worst for me too, just 3 months off Seroquel and still issues with sleep. Keep having faith and being positive; I tell myself that it will get better.

  • Giffordw August 25, 2015, 4:28 am

    I have been on Seroquel for 10 years. Started at 100 mg/day but psyc increased it to 200-350 at the beginning of May 2015 when I went of Ambien. A month later I developed a severe ear pressure/pain in my right ear 24/7. I have seen 2 ENTs and had a slew of tests and meds but nothing has helped. It is bad enough trying to get off of Seroquel without having pain.

    It has been 10 weeks now with no let up. I also have chronic pelvic pain. Consider yourself fortunate if you “only ” have to live with Seroquel withdrawal. I am about to go mad. I often wish I could die. Anyway, I read that other Seroquel users are experiencing the same ear problem from Seroquel. Does anyone here have a feeling of a plugged ear which won’t unplug since being on Seroquel.? If so, I’d love to hear from you. At least I can share my experiences. If you prefer my email address is [email protected]. -Wayne Gifford

  • Chrustine August 24, 2015, 11:43 am

    I started on only 25 mg for sleep. After a while it didn’t work as well. My insurance company changed policy and said they will only cover 50mg, saying that 25mg is not therapeutic. So I started taking the 50mg. After several years, I am now dealing we with heart arrhythmia. Not sure if it related, but I decided to ween down and stop taking. Took half for about 2 weeks. I am actually sleeping a bit better than I thought, but not great. Also I am experiencing nasty allergy symptoms.

    Constant sneezing and the itchies all over. Taking half a benadryl to take the edge off the itching. I have read many people complaining about that. The arrhythmia seems to be getting a little better and less often. Not convinced seroquel caused this. Although I have read that it can cause heart arrhythmias. I was put on a heart medication about 6 months ago, then the arrhythmias started. Just want to get off everything. Good luck to you all.

  • Toni (Australia) August 18, 2015, 3:31 am

    I have been taking quetiapine for 7 years after a serious nervous breakdown, and chronic severe insomnia. My highest dose was 75mg, which was like being kicked in the head by a camel. Over seven years I have reduced the dose to 12.5 mg every three days. I’m still gradually tapering the dose, until I will off it completely. Even with this gradual reduction I am experiencing side effects, and I would never suggest for someone to go ‘cold turkey’.

    The symptoms of nausea, headaches and itchiness will be milder if one reduces slowly, and allow the brain to adjust gradually. Many of the milder side effects are similar to detoxification by fasting. I find that drinking lots of water mixed with fresh lemon juice, avoiding tea, coffee and alcohol, eating fresh fruit and veggies and not eating if I don’t feel like it, do help. Detoxing is a process.

    I realize that I’m fortunate in that I was on relatively small dose, but I still feel that abrupt and total quitting is most likely dangerous in that you could refry the brain. I still have chronic insomnia, which I’m not sure how I’ll manage. I’m thinking hypnotherapy – has anyone tried this with success?

  • Lisa August 4, 2015, 1:52 pm

    Hi everyone, wishing you luck with your withdrawals! My story is a little different but also very similar. I went to the hospital two weeks ago for depression and suicidal thoughts. My psychiatrist diagnosed me with borderline and put me on 12.5 mg of seroquel twice a day. I began to have increased anxiety that resulted in some very scary panic attacks.

    I told my psychiatrist it didn’t work and he told me I just needed a higher dose. He put me on 25mg in the morning, 12.5 at noon, and 25 at night. My anxiety increased to the point that I was having panic attacks all day, as well as a heartbeat from 120-140 bpm. I was scared to leave my room and had uncontrollable crying. No nurse or psychiatrist would listen, because my doctor was the head psychiatrist of the hospital and “knew what he was doing”.

    Finally it got to the point where I was too nauseous to eat and was having diarrhea all day. I took myself off the seroquel 4 days ago after calling my pharmacist and being told that all of my experiences were potential side effects. Thankfully, my anxiety has subsided to the point where it is very manageable. However, I am experiencing insomnia, nausea, muscle twitching, and the worst is the irregular, fast beating in my heart.

    I am hoping that since I was only on the drug for two weeks, my withdrawal will be quick. I am so angry with the hospital for putting me on this drug in the first place (borderline is not an approved use for the drug) and for not listening to me when I complained! I almost wish I hadn’t gone to the hospital in the first place! I am so glad I was able to talk to my pharmacist.

    I have had temporary TD from a medication before and have no trouble believing that if I had stayed on the drug it would have happened again. My main message is always check the side effects of a medication before you start it!!!! Don’t take your doctor’s word that it will work for you!

  • Rachael August 1, 2015, 11:40 pm

    I’m day 7 after stopping my 25mgs dose. The horrendous itching seems to have subsided – I ended up getting some Piriton (antihistamine) from the pharmacy to get me through and it worked. Also Piriton made me drowsy which was good to combat the insomnia. It’s a tough ride quitting this drug – I’ve been on 50-75mgs for 9 years but i was sleeping recently because of the jumpy leg movement symptoms.

    I figured that if I couldn’t sleep because of this side effect, then I could put up with a bit of insomnia whilst I quit it completely. I’m not claiming to be out of the woods yet as I’m also experiencing some racing heart beats and general agitation… and so I’ll probably post again next week to report back on the withdrawal process. Just want to say thanks to everyone posting on this site as its been a lifeline regarding symptom awareness.

  • L July 26, 2015, 10:36 am

    Hi guys. I posted above, a few months ago. I tried to get off in January. I did it too quick. Ended back on 200 mg. Been on this drug more than 2 years, highest dosage 600 mg. Since May, I’ve been tapering from 200 mg. Did it real slow. Cut the 25 mg tablet into halves then quarters so I could do (approximately) 3/4, 1/2 then 1/4.

    I had my first night off without it last night, as the night before I couldn’t remember if I took 1/4 or not then thought, f*ck, may as well go off now then. Bit early as I’d only been on 1/4 for a week and not what I had planned, but there you go. Will go back on 1/4 if I can’t deal with it. Last night, had sleeping issues but that’s to be expected. Want to let people know, go slow. Go real slow and it will be OK.

    First few days of dosage drops are hard work. Went from 200 to 150 mg first time and it was quite hard. Some of the dosage drops have been hard to process. But I keep going to bed same time every night, started drinking hot milk and got an eye mask (am sensitive to light disturbance), etc, etc, all to try to up my chances of sleeping. Some of the dosages I stayed on longer cause they took my body/brain much longer to adapt to, especially at the lowest dosages.

    As I say, last night was not great for sleep. Am also a bit itchy. But will see how it is tonight. If it’s not great, will go back up to 1/4 and stay on that for longer, as had planned to stay on it much longer than I did. Had some good things from tapering. Glad to hear my own thoughts again and feel more alive. Best wishes for everyone here.

    • Lucie Duquette September 7, 2015, 5:51 pm

      Yes, there is some positive things in all of this; I too felt more alive, could focus longer on reading and creative thinking. I have tapered slowly over years and months. The last two months I was not taking any and it was hard but manageable, but on the beginning of my third month; the insomnia, fatigue, crying (mostly because I had not slept enough), and itchiness all over my body got quite troublesome so I took half of 25 mg for three nights in a row now, and the symptoms went away. But I don’t want to go back or stay on this medication.

  • Jax July 20, 2015, 9:01 am

    I have been on quetiapine for 7 years. I Am on my second night drug free. I feel nauseated heart burn extremely anxious unable to sleep worried how I will function come morning. I experienced the severe weight gain the dullness the fatigue everything you all have described. I have come down from 16 different scripts to 6. My fibromyalgia is killing me and my ulcers and depression and borderline personality disorder seem to be under control.

    This is absolutely one of the worst drugs I have ever been prescribed. Coming off of the quetiapine is worse than the withdrawals I had as a young adult quitting illegal drugs and alcohol. I wish only the best to all who are battling this addiction and the withdrawals we are all suffering because of it.

  • Roxanne July 14, 2015, 9:58 am

    I had been on 50 mg of Seroquel for approximately five years when I attempted to quit. My psychiatrist said cold turkey would be fine, but I went down to 25 mg for one week before quitting. Almost immediately I suffered insomnia. Weeks into quitting I had heart palpitations strong enough that I went to the ER. My whole body felt as if it were under pressure. My attention span was limited, my thoughts were becoming more rapid, and my sleep was limited. Three months into quitting I had a psychotic episode. It was the worst episode of my life, and I had been living with bipolar for 20 years.

    The episode was bad enough that by the end of it I was charged with three felonies, spent five months off of work, and was in and out of hospitals. After the episode I went back on seroquel, but at 100 mg. It’s been over two years and I am currently attempting to go back to 50 mg. So far I am only experiencing insomnia, but it has only been three days. I don’t know if I will ever be able to quit this drug. Honestly, this drug and my body’s response to it terrifies me.

  • Worried July 14, 2015, 4:19 am

    Currently night one after taking seroquel for two nights this would be night 3. I felt nauseated about 24 hours after my last dose of 100mg, and now laying in bed I have a headache. I also didn’t take my 80 mg of Prozac today, and I also took another 10 mg of dextroamphetimine for a total of 20 mg which is 10 more mg than I normally take which I thought would help me counteract the extreme lethargy I’ve encountered after day two of seroquel.

    I was suicidal over the weekend prior to seroquel and went to the ER, and asked for seroquel after asking around on a self help website. Looks like this drug was a mistake, I should have known better. But my suicidal ideations are gone. I will be tapering off the seroquel ever so slowly, and resuming my Prozac thanks to all of your submissions.

  • Bella July 13, 2015, 9:19 am

    I’m now 15 and was put on Seroquel just as I turned 14. I went through a phase of depression and self harm, and I didn’t realize what I was doing because I was in boarding school, and no one cared what I did. Until a student told the nurse and they sent me to a Psychologist and I got put on this drug. I already had problems sleeping, not too bad but I couldn’t fall a sleep easily. The drug knocked me out totally I didn’t go to school for 2 weeks.

    I was on 50 mg for a while and for the last few months 25 mg this summer I wanted to get off it so my doctor said to cut them in half. And now I really can’t sleep without any sleep medication like melatonin. I hate it so much and I wish I could just fall a sleep like I use to when I was younger. I also am scared or worried a lot, sad and some of my friends have told me I seem different. All I want is to be back to normal and get a lot of sleep.

  • Alexandria July 7, 2015, 3:05 pm

    I’ve been on Seroquel for 6.5 years, the doses ranging between 200mg to 1800mg. Most of the time I was taking 600mg. It was originally prescribed for BPD and psychosis when I was 18. The drug helped me a lot, but the withdrawal is hell. I tapered from 600mg to 300mg over 3 months, but then my doctor said to ignore the psychiatrists idea and come off that 300mg in 2 weeks.

    I’ve been off it three days and have had 15 minutes of sleep. I’m taking benzos to ‘help’, but they don’t do anything. I am going crazy. 72 hours awake is just not normal and I can’t stand it. I’m so scared of how long I’ll go without sleep.

  • Ella July 7, 2015, 6:26 am

    I’ve been on 50mg of Seroquel nightly for about 95% of the past twelve months, and only in the past few weeks have I reduced it to 25mg per night after commencing sleep restriction treatment (Seroquel was prescribed for insomnia). The past two nights I’ve taken none at all. Naturally I expected symptoms in regards to sleep (I’ve had a collective six hours in the past 2 days) but with that came a host of other troubles.

    Part of the reason I couldn’t sleep last night was because of flu-like, boiling hot to freezing cold sweats. I’m feeling depressed again for no particular reason. I have a headache that won’t go away. Today I went to the GP to determine the cause of my unbearably itchy mouth/throat, his opinion was surprisingly the Seroquel, hence I’ve come across this website. Even though it’s the middle of winter I’m doing a ridiculous amount of sneezing.

    I didn’t think such a tiny dose could cause so much trouble! Clearly I’m not alone though. Tonight I might attempt to cut the tiny pill in half so I’m taking 12.5mg. It can sure be a difficult, painful process. Good luck to everyone tapering themselves off… hopefully it will be worth it.

  • heidi July 5, 2015, 5:28 pm

    My husband was tapering from depakote, then seroquel. Depakote was no big deal, however seroquel, was a HUGE problem, police were called in and the police psychiatrist. NO IDEA that he would have these kind of withdrawal symptoms he has suffered everything on this list including symptoms of tar- dative dyskensia symptoms. My husband is presently in a nursing home 40 miles away from our house, and moving to a boarding place after that required by the courts.

    He is a mess, continues 5 years 28 drugs later messed up and unemployed being on disability. He is 60 years old and I do not hold out much hope for him. His public defender screams at me blames me for everything, the city attorney does not recommend that the protective order be modified, and by the time this is done, my husband may even forget who I am because one of the side effects of seroquel is early onset dementia which is what they have NOW diagnosed him with.

    He has been diagnosed with: alcoholism, (he does not drink) anxiety/panic disorder, mania, bipolar, psychosis, and now early onset dementia? Sounds like no one knows what they are doing. My opinion is he is a weak man and could not handle his mom and dad becoming sick on top of the stress on his job. Anyhow he is disabled non functional and a emotional train wreck thanks to these medications.

  • Kitti July 5, 2015, 12:53 am

    Hello everyone. I have read most of your posts and I’m really scared. My doctor prescribed 400mgs of seroquel for horrible insomnia I was having a year and a half ago. I don’t know when, but I started only taking 200mgs at one point early on and didn’t notice any problems. I have been wanting to get off it for awhile and read about the horrible side effects it causes. I don’t know if I gained weight from it, but I hardly eat anything and my weight has seemed to stay the same judging by my clothing sizes.

    The medicine also costs a ton and I don’t want to waste money on this poisonous stuff any longer. I began tapering really fast last week because I was almost out and was fine until my last dose of 50mgs two nights ago. I knew it was probably bad to taper so quickly, but when I called the pharmacy they told me there were no side effects to worry about. I lost my dog who I’ve had for 18 years a few days ago and the whole thing caused me to be depressed. I am still depressed, but I think a lot of it has to do with quitting seroquel so fast.

    It’s a weird kind of depression so I know it’s not just because of my dog. I am glad I am able to feel sad over it because I took antidepressants when I was younger and hated it because I couldn’t cry. I like having emotions and a lot of you said you felt emotionless on seroquel. Before the insomnia I suffered a year ago I was fine and happy and not on any medications. It was nice. Last night I could not sleep after only one night without any seroquel.

    My doctor had originally prescribed three medications in the beginning, klonopin, trazadone, and seroquel for the insomnia and said I could keep taking them. I stopped the trazadone one cold turkey with no problems and still have a bunch of it. Last night I gave in and took some of it again because of the insomnia from stopping seroquel. I think it helped me sleep a bit but I still was only able to sleep for 3-4 hours. Today has been horrible. I am exhausted, nauseous, depressed, and have a headache.

    I want to take a nap but can’t. I am going to get more seroquel as soon as possible but the pharmacy always takes a long time to fill my prescriptions. They are also closed on the weekends so I have to endure at least two or three more days of this. When I finally get my prescription I, going to taper a lot more slowly, but after reading all of the other posts here I’m sure I’ll still have to go through this hell again. I’m sorry all of you are going through horrible withdrawals.

    I should have never taken this terrible stuff, but at the time I was desperate and my doctor gave it to me like it was harmless. I have to work tomorrow so I hope I will be able to function better than I am today. All I feel like doing is laying on the couch…

    • Kelly November 13, 2015, 6:09 pm

      Hi, I can relate to what you are going through. When my dog died 5 years ago, it threw me into a massive depressive episode for months followed by extreme mania which eventually landed me in the hospital. I am off the seroquel finally for two weeks and it is miserable. But worth it in the long run I think.

  • Jonathan July 2, 2015, 6:13 pm

    I have tapered off Seroquel over the past few months. I was at 150 mg, and tapered down by 25 mg each month. I noticed some anxiety, but not too much. Then a few days ago I went from 25 mg to 0. My anxiety went through the roof, I could only sleep about 3-4 hours a night and my whole body itched horribly for almost two days! Now it’s day 4 and my itching is much less. Hopefully I’ll sleep well tonight. :) I’m sure this will pass too. Working out helps.

  • Nancy G July 1, 2015, 9:37 am

    This isn’t OK. I took 25mg x 2 a day to enhance Zoloft and was extremely allergic to both. My PCP ignored my complaints, I got angry, which turned into rage and aggression, I lost my house, some friends. 6 weeks off of it and I am still having screaming nightmares. Every comment I read, not only here, but elsewhere, indicates that this drug is a nightmare. Are there any lawyers out there who want to take this on?

    • Elektra July 12, 2015, 12:00 am

      Re: the part of your comment about lawyers…there have been reams of lawsuits over Seroquel. AstraZeneca, the maker of Seroquel, was even forced to pay the government over $500 million for illegally marketing the drug for off label uses. Sadly, that amount is roughly equivalent to 4 months of Seroquel sales alone. The system is so broken at this point that lawsuits aren’t going to fix these problems. What we need is either serious legislation (good luck on that) or criminal charges for specific individuals.

      • Shannon Barnes February 7, 2016, 11:50 pm

        I agree with Nancy. This drug is a nightmare!! I think it is over prescribed. The withdraw symptoms were SO TERRIBLE!! I have so much energy now that I’m off of seroquel. I think seroquel should be discontinued!

  • Lind June 30, 2015, 1:18 am

    Hearing all of these comments makes me hopeful, but what I am going through right now makes me feel like I’d rather die than suffer through another day of withdrawal. I feel like my chest is going to explode, and the anxiety and heart problems are immobilizing and torturous. I am taking valium given to me by the hospital, but it isn’t helping….If I have to go through this for 90 days, I would rather die. I didn’t even take that much.

    I was switched onto Latuda (20 mg) and they are gradually taking me off my 100 mg of seroquel (which I have taken for 2 years). I have been taking 50mg for the last few days. That, coupled with the raise to 60 mg of latuda landed me in the ER. Please someone help me. I’m suffering so much…. I am back on 20 mg, but I am ready to give up. The chest paint is too much. Please help.

    • ktlady July 15, 2015, 2:50 pm

      Hey there, stick with it! When I came off Seroquel (I took 600 mg for 3 years) I began to have horrible panic attacks and anxiety like I had never had before. I couldn’t sleep, as every time I laid my head down I panicked and thought I was going to suffocate/have a heart attack. It lasted for a few months before I got it somewhat under control. Be wary of using any other substances (for instance I had to stop smoking marijuana as that was definitely making it worse).

      Know that it is only the withdrawal, and it won’t last forever! You can get thru 90 days of hell, it is only a slice of your life. I repeat, IT WILL GET BETTER. It sucks. It sucks so so so bad, but you have to just hold out. Try to distract yourself. Watch your favorite movie, spend an hour in a hot shower, exercise, do anything other than just let the anxiety consume you in a quiet dark space. Talk to someone you trust, if you can, or to strangers in forums like this online.

      Something else you can try: Write down your thoughts, then look at them and see if you can substitute or insert one or two words that completely change the whole idea/context. You can get creative or ridiculous if it works for you. For example, if I was thinking “I feel like I am going to die if I just lie here” you can change it to “I feel like I am going to melt into a pool of chocolate if I just lie here”. That kind of stuff helps ground me and distract me when my thoughts are in an anxious whirlpool.

      Make yourself laugh if you can. Realize that the thoughts/feelings you are having aren’t necessary, they aren’t the only way you are capable of being. But seriously. You will get through it. Take care of yourself. You aren’t alone. Look at all these other survivors here who felt like shit and made it to the other side. Best wishes to you.

      • Julie November 2, 2015, 5:38 pm

        Thanks for your comments! They give me hope!

  • Caitlin June 26, 2015, 12:56 am

    I’ve been on 200 mg of seroquel for about 9 months following my last hospital stay for a psychotic episode . While I can honestly say the medicine has helped (no psychotic episodes since starting it, better sleep), I am terrified of the withdrawal. About 24 hours after a missed dose, I begin with a migraine headache and vomiting.

    I recently lost my insurance and am in the process of signing up for a new plan (I turned 26 and had to get off my parents insurance). I tried making the seroquel last as long as possible before running out by weaning down for a few weeks but I am now completely seroquel free for 3 days and I can barely function. The nausea is unbearable (I’ve vomited 8 times in the past two days), I feel like I’m constantly carsick, and I am barely sleeping.

  • Brian June 25, 2015, 5:27 pm

    Hi everyone. First, I want to encourage everyone that’s suffering from seroquel to be strong. I say that as I’m in the throes of side effects from it. I started about 6 weeks ago and about 2 weeks ago started feeling brutal side effects: leg cramping, involuntary arm and leg movements, sweating, mouth/throat spasms, excessive belching, not being able to sleep yet having no energy to do anything. When I lie down I cannot get comfortable on any level.

    I told my wife it feels like I’ve been poisoned because there’s this extraneous, spastic energy coursing through my body, especially my arms an legs. I’ve never felt so bad EVER where I couldn’t get into a comfortable position in order to sleep. I was on 100mg and my doctor said I should stop it cold turkey. I verified that with her more than once and she said with the severity of my symptoms, this is the best route. My last dosage was 2 nights ago and I’m still getting the shakiness and restless leg thing so she prescribed Klonopin which has been a Godsend because it’s taken the squirminess away to a great extent.

    • Giffordw August 25, 2015, 3:00 am

      Klonopin also has severe withdrawal symptoms! You might be trading one poison for another.

    • Ben November 11, 2015, 6:02 pm

      Don’t take the Klonopin!! Klonopin was the thing that set me down this horrendous road, Seroquel was prescribed to get me off Klonopin and I don’t honestly know which is worse.

  • Sarah June 15, 2015, 3:49 pm

    I have been on Seroquel for 22 months. Last night was the first night in almost 2 years without Seroquel. I started taking it when I was hospitalized with mania from taking trazadone and zoloft. I had an allergic reaction on the lowest dose for about 5 days! I was a hot mess so I was in the hospital for 10 days and I started taking this drug not knowing anything about it. When I checked into the psych ward, the nurse gave me seroquel and told me to SLEEP. I slept 14 hours straight that first night. It took me weeks to get adjusted to this medication.

    I was in a constant haze and always tired. When I was released, was put on 600 mg for about 15 months. With the help of my pdoc, I have been tapering from 600 mg down to 25 mg. I’ve been tapering pretty steady for 7 months and last night was the first night without it. I took 50 mg of benadryl and only slept 2 hours from 10 to midnight. I snapped wide awake and couldn’t relax or even close my eyes. It’s like I drank a pot of coffee I was so wired. I managed to take an hour nap in the morning. I feel like crap and I fear what is to come in the next few days.

    I’m going to try GABA supplements tonight and skip the benadryl. I see my pdoc at the end of this week and I hope he has encouraging things to say. I don’t want to get back on this drug. Each taper went really well for me with no withdrawal side effects. I’m hoping this is just a hurdle to get back to “normal” with time. Good luck to anyone trying to get off this drug. It was a lifesaver for me at the time but I no longer need it! Diabetes runs in my family and I am obese from this medication. I want to live a healthy life with my daughter and husband.

  • JR June 14, 2015, 10:57 pm

    I have been on Seroquel since 2009 150mg and in 2012 I tried to get off the drug. The first time I tried to get off the drug I didn’t take long enough to wean myself and I had horrible withdrawal symptoms. I was vomiting, sweating, had severe anxiety and basically my mental health went in the toilet. My doctor tried several other drugs but they all had horrible side effects and in the end I went back and begged to get back on Seroquel.

    So I started again with 50 mg and was back up to 150 mg. I also started to cry all the time and asked if I could take another type of antidepressant so he prescribed me Viibryd. The combination did the trick and I resigned to myself that this is what I needed to do to function. After a few months on both these drugs I was finding that I was so tired that I asked the doc if I could try going down to 100 mg of Seroquel and I did that for about 1 year.

    I felt the Viibryd was working for me very well and so I decided that I would again try to cut my dose of Seroquel in half and take 50 mg. I did that for a year. In February of 2015 I had my physical. My cholesterol went up, I was up to 180 lbs (I’m 5’3”) and on top of everything else I started to have these very vivid dreams and was not sleeping great. I changed my diet even more (I eat mostly fruits, veges, beans, lean meats, cut way back on sugar and started to exercise more) I didn’t lose anything so I decided at that point that I was going to try to get off this awful drug one more time.

    I started to cut the 50 mg in 1/2 and did that for about 2 months and then I cut the 50 mg into 1/4 and did that for another month then stopped. My pdoc is on board with me in this endeavor. So I have not taken Seroquel for 3 weeks. Sleep is definitely an issue – the first two weeks were rough. I am taking a combination of melatonin, hops, l-theanine and valerian supplement. I’m not sure if it is helping but I am getting at least 4 hours per night.

    I am extremely fatigued and I swear every muscle in my body hurts. But that being said – I am not overly anxious and I feel fairly normal mentally. I am still struggling with weight but hopefully my metabolism will speed up. For anyone out there reading these posts… Do not try to get off this drug cold turkey. I know it took me about two years and you may not need that much time but don’t be in a hurry. Take your time, cut your doses small amounts at a time and give your body time to adjust to the smaller doses.

  • Ruby June 13, 2015, 9:52 pm

    I was prescribed Seroquel, for Major Depressive Disorder 3 and a half years ago. Initially I was on 100mg and then that was increased to 200mg. It really helped my mood and my sleep at the time and enabled me to function, however I noticed very rapid weight gain, especially after the increase to 200mg, and for this reason I cut it down to 100mg about a year ago.

    I didn’t notice any significant side effects, but thankfully, I felt less sedated, my voice stopped slurring so much in the mornings (I teach!) and my weight stopped increasing, although I couldn’t lose any of the weight I had put on, even with diet and exercise. I was putting up with the weight for the sake of my mental health, but after learning about side effects like high cholesterol, blood pressure and also diabetes and under active thyroid (which are in my family) about a week ago, I took the plunge and cut it down to 50mg.

    I was really scared to do this. I was worried I wouldn’t be able to sleep and it would affect my mood, but I have been okay so far. I had difficulty sleeping for the first couple of nights, but I am sleeping some now. I am hoping to come off this drug completely, lose weight and for my body to return to normal. If my mental health deteriorates I would seek an alternative drug, although I acknowledge it helped me at a very difficult time when antidepressants alone didn’t. Some months ago I starting withdrawing from a Diazepam (Valium) and that had much worse withdrawal effects for me.

  • Elektra June 11, 2015, 8:20 pm

    I’ve been on Seroquel 150mg XR about five years now, along with several other meds (Zoloft, Abilify, Adderall, and Wellbutrin), ostensibly for bipolar II. My husband and I want to have children, which means I have to get off all these medications at least for a while. Between the Seroquel and the Abilify I also went from 110lbs to 180 lbs in just over two years, and this was another motivator to get off the meds. (I used to be an acrobat, but I lost all that thanks to the relentless weight gain).

    Anyway, I started the process of tapering off this past January, beginning with Adderall. I got off that successfully and was encouraged to keep going. Now I am trying to get off the Seroquel. I went down to about 100mg XR for a month, during which time I began to have trouble sleeping and very vivid nightmares. I was familiar with this from trying to get off Seroquel before, so I took it in stride and after a month I continued down to 50mg XR.

    I am still having trouble sleeping and vivid nightmares but now I am taking melatonin, and that has been enough to keep me asleep for a few hours at a time. Unfortunately, I am also having some more serious problems. I am very depressed and moody, and have noticed that I am having more suicidal thoughts than usual. So far it’s manageable, but I’m worried about where things are going.

    I guess I am going to hang out at this dose for a month or maybe two and see whether things improve any. There have also been some good parts, such as the fact that I can feel the chemically induced lust for sweets fading gradually. In all I guess I feel lucky things aren’t worse, but I’m still pretty damn depressed, and I’m concerned about what the final transition off is going to be like.

    • Elektra July 11, 2015, 11:44 pm

      I just wanted to come back and update to say that I went through a bad patch after transitioning to the 50XR, but after a week or so it passed. I have now switched to 50mg non-extended release, so I can continue down to 25 and then 12.5 before going off altogether. This process is long (almost a month for each step), but so far the suffering has been minimal, compared to other people’s stories.

      • Elektra September 30, 2015, 8:34 pm

        Just wanted to leave an update to say I’ve been on 25mg for about a month now, and tonight will be my first night entirely without Seroquel. I’m nervous but hopeful. Since I switched off the XR I’ve had a lot of difficulty sleeping and a lot of REM rebound (vivid dreams/nightmares), so I’m a bit worried that will get worse. My psychiatrist prescribed Prazosin for the REM rebound, but I’m not sure I want to take any more medication, so I’m probably going to try going without it. Anyway, I will come back and update when I’ve been off a while.

        • Elektra November 11, 2015, 5:28 pm

          Just wanted to leave an update to say I have been completely off Seroquel for over a month now, and I’m doing fine. The final step off the 25mg wasn’t that bad, except for some difficulty sleeping. I want to encourage everyone who reads this: you CAN get off this drug, if you go very, very slowly. I wish you all the best of luck!!!

          • Julia March 2, 2016, 3:12 am

            Elektra (and anyone else with a similar experience) I need your help here so I hope this post is still on your radar! I was hospitalized in 2010 when I was 18 with severe anxiety and depression. Now that I know more about mental illness It was almost like a panic attack that lasted for a week. Finally I begged my parents to take me to the hospital and they did where I was then assessed and checked into the psych ward, the scariest time of my life.

            Please note this was very possibly brought on by drug abuse through my teenage years including excessive marijuana use and occasional psychedelics as well as ecstasy. Like this exacerbated an underlying condition I already had. NOTHING worked. They tried xanax and regular seroquel which temporarily helped but hours later I would be breaking down again. Finally they prescribed me Seroquel XR and I woke up the next day feeling almost like myself again.

            In the years following I went from 250 XR to 150 XR and most recently I got down to 50 XR – the lowest dose. My current psychiatrist and my step-moms sister (a therapist) thinks I should be getting off the drug since it’s somewhat of an unconventional drug for my diagnoses (anxiety, depression, and panic attacks). I am also taking 10mg Lexapro and have ativan when I almost never take for panic attacks.

            The past week and a half I have tried to take regular seroquel instead to start getting off of it completely. My doctor said to take half of 25 mg (12.5) in the morning, lunch, and before bed for six days then take it at the morning and night for six days and then to just at night. So far I have gotten to two times a day and I can feel myself getting anxious and sad again. I have no sex drive, I am not interested in what I normally am, and am just overall sad. I also am severely constipated.

            Today I elected to go back on the XR. I am only 23 and to me at this point it is more important to have good quality of life. But I don’t know if this is the right decision. I keep putting it off – but I have tried to take regular seroquel instead before and have ended up going to the ER with severe panic. I don’t know what to do really – for now I want to live my life with the XR, but one day if I have kids and want to get off I don’t want to lose my sh*t again. Any advice?

  • heidi June 8, 2015, 8:08 am

    My husband was on 800 mg of Seroquel and 1500 mg of depakote. He tapered off depakote not too much trouble then tapered off Seroquel and 30 days after taper off, he started getting violent ended up in jail, back on seroquel but 200 mg, he has been diagnosed with early onset dementia. This is cause by the medication and I am scared out of my mind the last 5 years have been a messed up hell anyone have any suggestions? He is in a nursing home with a restraining order I cannot contact him, this is horrific. I am scared he won’t even know me by the time the courts get around to letting the restraining order go.

  • Mario June 7, 2015, 5:04 am

    I have been prescribed 1200 mg of Seroquel per night, for major depression and insomnia. I have been taking this dose for over two years. I am gradually tapering off by taking a quarter of my 400 mg tablet (100 mg) per night. I have never had any blood sugar issues, but I am noticing that when I am hungry if I don’t eat almost immediately I feel extremely tired, almost as if my blood sugar is extremely low.

    It has been noted that Seroquel in high doses, such as mine does increase blood sugar levels. I now regularly exercise in order to alleviate withdrawal symptoms. I have tried quitting cold turkey, but I get less that 1 hour of sleep per night. I would recommend tapering over quitting cold turkey. Be sure to inform your psychiatrist of any and all symptoms. Good luck and easy does it.

  • debbie June 2, 2015, 6:03 pm

    I unfortunately forgot to get refills and it was 4 days till I was able to get with my doctor. It was intentional. By the 4th day I was sweating, sick, and couldn’t sleep. Don’t go cold turkey it’s awful.

  • Stephanie Templeman June 2, 2015, 3:37 pm

    I am so sorry others are going through these symptoms of withdrawal. But at the same time, I am so relieved I am not going crazy and it’s not just me! I feel so unwell; flu-like symptoms, itching and the sweating is all-consuming! I thought I had a horrible virus. I haven’t slept for 3 days, one minute I feel exhausted and try to sleep, the next I am tossing and turning in bed unable to sleep and suddenly feeling wide awake. I cannot stop crying, I feel so low and have horrible thoughts creeping in. I cannot believe coming off a medicine can be so horrible!

  • Gt May 31, 2015, 3:28 am

    I just wanted to say as someone who has struggled to first get off the serotonin antidepressants for 7 years. That the struggle getting off of this was the same as you describe for Seroquel. It made me feel so much better to read this and know that I am not wacko. I was one of the ones who experienced severe withdrawal symptoms. It took 6 months for them to go away getting off the Zoloft.

    I’ve been taking the Seroquel for almost 10 years and now that I don’t take an anti depressant that Seroquel seems like it is way too much. I am so hung over all day. So I’m trying now to taper off of this medication as well. I only took this for sleep. I couldn’t sleep on my own and nothing else they gave me worked but this. I appreciate the candid description of what I can expect and knowing what is causing you to feel a certain way is half the battle. Thank you.

  • Kirsty May 26, 2015, 6:57 am

    This has been such a helpful website, I am so glad I knew what to expect. I take Lamitrogine too so decided to come off Quetiapine (having been on it for 5 years) because of side effects, such as severe palpitations, anxiety at night and ballooned weight (3 stone) I was originally on 600mg for Bipolar. Taper has been OK, a few days of vision and auditory problems each drop but manageable. I’ve now been totally off for three days, as expected insomnia has hit and snatched dozes full of vivid dreams.

    There’s been some nausea and anxiety levels are changeable and yes, the itching can drive me wild at times. The worst thing for me has been the ‘Hay-fever’ though! Having never suffered with it in my life before it has knocked me for six. Streaming eyes, nose, sneezing my lungs out, feeling proper rough!!! I have been reluctant to take antihistamine, not wanting to replace a drug for a drug, but I need to go to work!! So I think I may have to…

    I’m still bewildered as to how this powerful drug is administered with no warning about its potential long term effects, what its actually doing to your body and how hard it is to come off it!!! I’m sticking with it, I will not be going back in it if I can help it. Hope this is helpful.

  • curt May 23, 2015, 5:01 pm

    Took me a year to taper off 300mg of seroquel. I crushed them used a digital scale and lowered the dose 5 to 10 percent per month. I’ve tried cold turkey – it’s not worth the pain.

  • Scott May 22, 2015, 5:38 am

    Hi I can help… I think I might have the solution to help withdrawal… I’m still on, but when I can’t afford medication I take phenibut and I’m able to function. Take 3 days on, and two days off. I think it may help some of you, as it has helped me. Do not overdue the phenibut and do not take for more than 5 days tops, always take a few days off. Tolerance builds fast. This is a gaba that passes the blood brain barrier.

    You will need a break as you build up a tolerance fast. The off days might be a little tough but phenibut is long acting. I’m not advertising anything here just found this forum and I think I can help some people here. I have extensive experience with phenibut…. Email me [email protected], I can help give you more information.

  • Marianne May 21, 2015, 2:36 pm

    Two weeks since I stopped with my last pill. I’ve been up at 800 mg, taken it for three years, and weaned myself off it so the last pill was 50 mg. And yet, I am still feeling really sick. I don’t get out of bed, I am constantly nauseated, itchy, achy. I can’t get to sleep and I wake up once I finally sleep. I can’t stand smells of anything and if I sit up too long my head is dizzy.

    If I had known how this would effect me I’d signed myself in to a clinic for it. Or not stopped. But I wanted to stop because of my usually bubbly personality, which is now lethargic and totally energy-free. I sleep 16-17 hours per day and I can’t work. I hope to find myself again, even with my Bipolar 1 disorder.

  • Lykke Kingston May 21, 2015, 10:00 am

    I was put on Seroquel in Denmark when I made a much-needed visit to the psychiatrist. Needless to say that I didn’t even NEED the Seroquel; when I got back to England, I was told that the doctor could have killed me with the dosage I was on because I didn’t even NEED it and he insisted that I go cold-turkey from Seroquel. I’ve been off it for a week and I already feel like crap. I’m waking up in cold sweats and today I was almost sick, I am nauseous, weak and the muscle pain is just unbearable. My mum is looking after me whilst I take the time to recover and has bought me painkillers today.

  • Rachel Forbes May 19, 2015, 6:45 pm

    I began taking Seroquel a little over a year ago. I was in a mental hospital and they went up to 500mg for me to sleep. I stopped taking it a week ago and it has been terrible. I can’t sleep, I’m nauseous, migrains are a constant thing. Also my motion sickness has gotten worse so much so that I can’t watch presentations/movies I have to report on in class. Reading on my phone hurts my eyes and head. I can’t concentrate on anything for long and my joints are aching. I am not looking forward to this process but I believe after I will feel much better. I just need to get through these next few months.

  • Kelly May 12, 2015, 7:57 am

    Hello everyone! Although I didn’t know what it was that was going on with me, I now know (strongly believe) I was extremely sick from abruptly stopping to take my seroquel. Originally, I was put on 300 milligrams due to having night terrors and panic attacks in my sleep, which were partially caused from getting so severe that I was starting to get seizures and syncope episodes while awake, that there was a real concern of this happening to me while I was asleep with no one aware.

    Besides those ailments, I was diagnosed with PTSD and type 2 bipolar disorder for severe bouts of long lasting depression, as well as occasionally accompanied by 2-3 day periods of “mania” or cycling, where I couldn’t sleep for days. Amongst other things, these were the main causes for the doctors to put me on seroquel. After a few months, I asked to be dropped down to 1/2 my dose, or 150 milligrams at night, but was told to take 1 (100mg) pill during the day as needed for anxiety, etc.

    Well, I decided that I was sick of having to be a 30 year old woman on so many strong medications and decided to rule out the seroquel unless it was absolutely called for (thankfully I’m taking Lamictal for my unfortunate ailments, and it seems to helping a great deal so far!) Anyway, about Saturday night of last week, I started to notice I wasn’t feeling 100%, but nothing to really speak of, until about early afternoon on Sunday. Out of the blue, I became extremely nauseous, feelings of hot flashes, extreme burning sensations and soreness in my calves and down to my feet, like I’ve never experienced before.

    The nausea was unrelenting until I finally vomited. Thinking I would get some kind of relief afterward, I tried to sip some room temperature water and eat a few French fries to try to re-hydrate myself and make up for what I had just lost. Horrified, I took no more than 3 steps n out it all came again. Besides the constant feeling of having to vomit, I was very uncomfortable, pale, weak, and sleep deprived. If I did happen to fall out for a very short period of time, I had terrible dreams of a constant spinning sensation, along with a feeling of not being able to breathe, causing me to wake up drenched and afraid!

    Now I became even too scared to fall back asleep! The only odd thing that would happen every so often is it would seem to feel like I was finally getting some relief from the constant nausea and intense leg and feet pain(s), and even possibly getting better, until WHAM!!! It would come right back again. This lasted from being extremely mild on Saturday night all the way through Tuesday afternoon! By then, I was so dehydrated and weak, and just plain old sick of being sick and tired, that I got up enough energy to make it to my mother (for there is no one like your mother when you’re sick, no matter what age you are).

    She immediately had me wash my face with cool water and sat me down while running to the pharmacy to get me some Dramamine (for motion sickness) and a case of pedialite (to help hydrate me and give my poor body some electrolytes, etc.) to help strengthen my immune system back up. Although I still wasn’t totally out of the woods, the crippling feeling of extreme nausea dissipated. It is now going on 10 days, and although I’m feeling much better.

    I still have leg/muscle/joint/nerve pain down the back of my right leg, I’m thankful that is over, especially when you have no idea what caused it!! These medications are no joke and should be explained to patients in greater detail about both the pros and cons of these strong drugs. NEVER AGAIN!!!!

    • BeenthereDonethat July 14, 2016, 7:30 pm

      Dramamine helped the nausea and vomiting? That’s what I’m looking for!

  • Rachel May 10, 2015, 6:18 am

    Thank you for this website. I have been taking 250mg Seroquel nightly for two years. It was prescribed for anxiety, depression and insomnia. I tapered down to 125mg, and about four days ago I decided enough was enough and I stopped completely. I have gained over 40lbs since starting this drug, and I haven’t felt a proper emotion in I don’t know how long. It REALLY helped me sleep, but it turned me into an overweight zombie.

    The withdrawal so far has been what I expected. I haven’t slept more than 3 hours in about two days or so. I feel tired, and wide awake at the same time. My moods are going up and down. Mad, angry, irritated, nervous, anxious and sad. I have no appetite and ALL the bones in my body are aching like I have severe flu. The itching is moderate, as is the nausea.

    What I will say is that despite all this, I feel like this is the best decision I have made in a LONG time. It’s only been four days and my libido has sky rocketed. That alone, is amazing because I have not been interested in sex for about a year and a half and it was obviously affecting my relationship. Even though I can’t sleep and I’m pacing the house at night, I feel like I’m coming out of a dead existence, and I like it.

    I feel like I might be coming back into my own again. I don’t care what my doctor says, I am not going back on it. I’m sure it helps some people, but for me I think it just wasted the last two years of my life.

  • Deniesha Mercer May 6, 2015, 4:24 pm

    Well I’ve been on seroquel since 15. Started at 800 stopped cold turkey at 600 I will be 19 next month. I went cold turkey and its been 3 weeks. I’ve had headaches and vomited like 3 times. But overall the withdrawals aren’t as bad as I thought, I have a strong body. I’m still doing my normal day-to-day life things. My body still hurts, but not as bad. And my taste-buds seem to like salty foods instead of sweets.

  • Jacey Phillips May 6, 2015, 5:34 am

    I just cold turkey quit my 300mg daily dose of Seroquel because it’s personally too expensive to pay for without insurance. I’m glad I found this page because it just helped me realize a lot of my symptoms are withdrawal symptoms. Like EXTREME itchiness all over my body, the heart rate changes, dizziness, and foggy brain. This is really tough.

  • Russell April 26, 2015, 11:00 pm

    I had been on seroquel 200 mg for 10 months when I had stepped down to try a new medicine. From doing so I had a psychosis breakthrough and it destroyed my life for a month (and still is). I experienced delusions of being possessed because of uncontrolled muscle movements in my arms, legs, and neck. I went back up and everything was better… for a week. So my doctor told me to taper down over a period of three days which I now understand is not enough time to do so. I tried abilify for 4 days, but it added even worse side effects so now I am on nothing but my original mood stabilizer (lamictal).

    I now have symptoms such as nausea, constipation, extreme restlessness (can’t stop walking around), extreme anxiety, irregular heart rate when attempting to fall asleep, and the original psychosis symptoms from before(but not as worse this time. Its been close to a week this has been going on now and each day it seems to slightly worsen. I almost refuse to believe such a state of discomfort can last 90 days for me. Does anyone have any information that might help me to understand when this will end?

  • Rhonda April 23, 2015, 1:21 am

    I’ve been off Seroquel for about a month. My doctor did take me off slowly. The itching is almost unbearable!! I scratch my arms and blood pools under my skin like I’m on a blood thinner. I scratch and get red bumps that turn into sores. This is awful!! Wondering how long this will last.

  • Lel April 22, 2015, 1:10 pm

    Hi I’m Lel. I thought I was imagining my symptoms until I found this web page and all the wonderful entries. This is my first day of complete withdrawal from Quetiapine, having reduced gradually. I did not take my last 50mg last night and am ill with symptoms. my torso is covered in welts from itching, my head is in a vice and I just want to vomit.I should be exhausted from not sleeping last night and sweating, but my body and joints throb and my mind is jittery, speeding and I am irritable as hell.

    At least I do not feel alone with this. I just want to get off this toxic poison. I have never had psychosis or mania, but after my last bout of severe depression 2 years ago, I was put on 300mg of Q. I trust that staying on Paroxetine only will be enough for me. I send hopes to everyone that they may find the support and the courage to endure this awful withdrawal. I am reassured that this present condition will neither kill me nor last forever!

    • Lucie October 5, 2015, 1:15 am

      Hi Nel, your story is similar to mine. May I ask how long you have been on Paxil and what dose you are taking. I’m embarrassed to say; but I have been on Paxil 20mg for 20 years.

  • Jess April 21, 2015, 10:51 pm

    I’ve been on Quetiapine for just over two years now (I’m currently 16). I used to be on 600mg but it was tapered down to 200mg. I don’t remember experiencing withdrawal symptoms but I probably wasn’t aware that they were due to withdrawal and ignored them. I was prescribed because of the mood swings and psychotic symptoms of my ’emergent’ (as I’m under 18) Borderline Personality Disorder, as well as depression and chronic insomnia. Because of the excessive weight gain I’m trying to come off it, but the insomnia is horrendous and I feel run down and nauseous all the time.

  • Holly April 21, 2015, 1:07 pm

    I’ve been gradually tapering off of 900 mg of Seroquel. When I went down to nothing I got very sick. I initially assumed that what I was experiencing were symptoms of bipolar disorder since I wasn’t taking the drug. Then I realized I was going through withdrawal. Went back up to 300mg on the advice of my nurse practitioner, and this helped. There are still times when I feel like a dope sick junkie. I am determined to get off of it, and wish everyone else luck.

  • Borei Hoshech April 20, 2015, 3:58 pm

    After months on 300 mg of Seroquel (as an off-label adjunct to an MAOI for major depression), my psychiatrist and I decided I should go off. He had me take 150 mg for about a week and then go off it completely. He said I shouldn’t experience any side effects other than irritability two weeks after going off. I went off of it completely about a week ago, and I’ve had severe insomnia, nausea, and itchiness all over my body (but especially my scalp!) since then. This is still not as bad as going off of Cymbalta was for me last spring, but it’s unpleasant. I’ll go mad if it lasts 90 days!

  • Jules April 20, 2015, 4:41 am

    I feel really fortunate I was only on this for a month. The side effects of taking it for me were awful. I felt suicidal, worse than ever before, and I had other physical symptoms. I was on a 50mg extended release. I stopped taking it 4 days ago. Since yesterday I have felt so nauseous and couldn’t understand why. I thought I would google withdrawal symptoms and found this site. Hopefully the nausea will pass quickly, and thanks to some of the comments here I will try the phenergan I have to see if that controls it, or at least makes it a bit more bearable. I’m so glad I made the decision to come off it, but it has meant I’ve got a rapid referral back to the psychiatrist from my GP.

  • Amanda April 18, 2015, 12:17 pm

    I was diagnosed with bipolar and personality disorder. After I was put on many drugs from a horrible doctor and I checked myself in a psych hospital. I went with many months of not being able to sleep and became phobic of falling asleep. I was put on seroquel and Lexapro. I felt like a zombie and slept a lot. I had no sexual functioning. I gained weight and it raised my cholesterol – over 300. We moved out of state and lost our insurance, so I filled my last prescription. It’s been almost 8 months. I have went from 100 mg to 10 mg of seroquel.

    The last 3 days I stopped taking it and have had severe nausea, headaches and stomach pain. But I feel very lucky I’m not taking any meds and feel great other wise. I feel happy when I wake up and can actually get out of bed. I have read a lot of research and I am taking omega-3s and eating a lot of fish. I think that is making all the difference. I hope this continues and wish everyone the best and to hang in there.

    • BeenthereDonethat July 14, 2016, 6:55 pm

      Fish? LOL, right!

  • Mia S. April 15, 2015, 8:14 pm

    I read through multiple posts and am grateful to know that I am not alone. Seriously there have been many days where I have felt totally insane and miles away from an ability to interact with others. I had asked to come off of Seroquel XR 2 years ago and the RN talked me out of it. My doctor didn’t even know we had had the conversation. If you check in with a RN, NP, etc. – double check with your psychiatrist!

    I went in a month ago and demanded that I be taken off due to the many side affects I had been having due to taking the medication. Which were the inability to follow through, not holding down a job, getting lost in conversations, word searching, migraines, fatigue, 2 naps a day, rigid muscles, tremor had worsened and so confused. So here I am now 1 month into my taper. My taper began with 400 to 200 immediately along with Trazadone for sleep when needed. Immediately my symptoms got worse, I could no longer drive or operate kitchen appliances, we ate soup for a long time.

    Anger ran deep, I woke up hating the world and I mean hating everyone and everything. It had been a long time since I had had that thought process go on for days. I have been on Seroquel for 8 years, it was the fix all. I was put on this medication for PTSD, not sleeping and bad dreams. It worked for a while I felt alive again, and then the side affects stared kicking in. I gained 10 lbs and for me that is a great amount as I have a very tiny frame.

    Today I am clear, my tremors have lessened, still have migraines, some muscle stiffness, less yet still have the word searching problem going on and I still get confused, especially if I am under pressure. So today I am ready to get off of the last 200 yet after reading all of the above information I am really thinking about a longer taper. I’m going to visit family in NY and would really like to be able to function.

    I have a month and a half before I go. Last but not the least… I take this medication for needs that I no longer have and pay $1500.00 for 3 months to do so. My husband’s insurance picks up the remaining balance of $4500.00 for 9 months. Thank you all for submitting responses, they have helped me have a clear picture of what my taper may look like. I will check in in a couple of months and go from there! Thanks again all!

  • Elizabeth April 9, 2015, 10:34 pm

    I am finally off Seroquel but it took a lot to do it and I did it very, very slowly. I was on it for anxiety and, while the anxiety did not return I had lots of trouble sleeping. I have never before had insomnia except at the beginning of taking antidepressants. I was prescribed Trazodone to sleep and it worked well. During the time I was weaning off 150mg daily of Seroquel I gradually increased the Trazodone from 100-150mg at night under doctor supervision. I take 3 capsules of Omega 3 twice daily along with niacin and magnesium, vitamin D3, folic acid and one vitamin E. I also take a multivitamin and B50. I still have a bit of fatigue and headaches but all in all I feel really well. I’m not a doctor. This is just my experience and please don’t take what I’ve said as medical advice.

    • Giffordw August 24, 2015, 10:23 pm

      Did your doctor recommend all these OTC meds and herbs you are taking?

      • BeenthereDonethat July 14, 2016, 6:44 pm

        Yeah, I don’t buy these herb, vitamin, and homeopathic solutions. There would have been a lot more people here with success if they really worked, for I’m sure many have tried them. I think most of the posters touting them have a financial interest in doing so.

  • M. April 9, 2015, 10:09 pm

    Reading everyone’s posts has me a bit frightened to even be prescribed this drug in the first place. I have been taking seroquel for about 3 months for type 2 BP disorder. Prior to this I was unmedicated for 10 years (I honestly don’t know how I did it). I switched insurance companies and after seeing a new psychiatrist, I was put on lithium. I’ve been taking lithium for about 3 weeks and tapering the seroquel.

    There have been days where I have felt awful, and this whole time I thought it was just the initial side effects of the lithium… but after reading these comments I’m not so sure. I was taking 50 MG seroquel, then 25, now I’m on 12.5. I think I might just stop cold turkey and deal with it. I’ve already had trouble sleeping, vivid dreams, nausea, inability to exercise without feeling faint, extreme shakiness. The dr never even warned me about withdrawal symptoms. Ugh wish me luck. Best wishes to all of you in this crazy game of finding the right meds. It’s friggin hard, huh?

  • Herbie April 6, 2015, 3:47 pm

    Checking back in, at a bit over four months zero Seroquel. Doing just about perfectly fine now. Was still having trouble sleeping two months ago, and researched natural sleep aids. St Johns Wort seemed to be best bet, even though it seemed to solve insomnia mostly related to easing depression. Right at the one month period where it’s supposed to start working; (beginning of March, a tad over a month ago) it kicked in and now I sleep great.

    I was still having trouble with energy levels during the day however, and unrelated; I tried some ginseng powder at a local health food store. That stuff is fantastic! Elevates energy levels w/o the jitteriness that comes from coffee. Elevates mood too! Been on it for a month now. Best med ever, though I can easily fall into the trap of; ‘if a little is good, more would be better,’ and go into a minor tweaker binge. It’s good to be diligent on dosage. In the past month, twice I’ve gone a day w/o ginseng, and still been free of the listlessness I was associating with seroquel.

    (If you are interested in ginseng, don’t be scared of it’s $250/lb price tag. I bought $20 worth from the bulk section, and used about $15 worth in a month.) I’ve got another issue though, which may be related to seroquel w/d. While trying to fall asleep, about once or twice a month I’ll hear a sound like an electrical zap inside my head. Either a brief pop, or a short but sustained arcing. This has been going on for only as long as I’ve been off Seroquel, and off nicotine as well.

    Did a bit of poking around online and found it seemingly related to other pharm w/d, though none mentioned Seroquel. I didn’t cross ref to see if same company makes Seroquel and the other meds, but I could see it coming from a binder in the pills or something. It also seems to be connected to tinnitus, which I just noticed that others on this forum have mentioned. I also notice I’ve got minor memory lapses. I forget what I’ve talked to people about. My personal issues, not as much theirs.

    For instance, yesterday I talked to a clerk in the store about my dog, and ten minutes later when he was ringing up my purchases, I forgot what topics we’d ever covered before. Later, obviously, I remembered. This however, could be something I’ve always had and only noticed recently once I started giving a dang about other people. All in all though, I’d say I’m pretty much clear of issues related Seroquel withdrawal. It’s been rough. Paranoia, itching, sleeplessness, grogginess, mental fog and (perhaps situational) depression.

    All along in the three months while tapering off, and for at least three months while totally off. Interestingly to me, the biggest jumps in improvement were the couple days immediately post my posting on this site. So things DO get better, and I encourage everyone to push through. Just like quitting smoking, the intense period of withdrawals are better to deal with, than a lifetime of more minor side effects from remaining on the med.

    • Annie May 15, 2016, 2:29 pm

      Hi Herbie, thanks for taking the time to post. It is really good to hear that there is light at the end of the tunnel. There are so many horror stories about withdrawal that it is easy to forget that you can be free of the evil drug.

  • Pheora April 2, 2015, 4:12 pm

    I am on day 4 of being without the Seroquel. So far I am only tired and a little nauseous. I am not sleeping because my body has to learn to fall asleep on its own now. My brain seems to run all night. These few symptoms are just fine with me compared to the brain fog I was always in and the extreme weight gain. It got to the point I was adding 2 to 3 lbs a week and the medication was affecting my speech at times.

    Initially I thought it was the most amazing drug out there. And eventually I began feeling like a zombie or a puppet. I just feel that I will stick with my Celexa and therapy for now. My mental clarity is coming back and I do physically feel better. Results may vary. I hope this helps someone out. There is hope for coming off the medication. You have to prepare yourself for the side effects.

    • jacey May 6, 2015, 5:40 am

      Ok I’m on my 4 day cold turkey and I’m having the same inability to fall asleep. I had horrible weight gain with mine and my only other side effect is horrible itching. I hope it all gets better.

  • Bella Page March 31, 2015, 1:14 pm

    I am 46 y.o and was put on this a year ago by psych doctor to control repetitive thoughts and hopefully to get me up & out as social anxiety is a constant on my Bipolar I. I never thought as being addicted to these drugs, including my Klonopin 1 mg 3x’s daily PRN. My seroqel was introduced at 150, IN COMES OBAMA SCARE INSURANCE (Paid by my mother) and I must go In Network, New Doc after 5 yrs. He is 71, and cycles his patients through his old facility, The Psych Ward to keep his former co-worker & buddy busy, and go STRETCH those tired dogs by putting them up instead of doing Hospital Rounds.

    I went to see him on a F/Up visit because after he doubled my intake 150 to 400 mg, I walked into walls I was leaning, and (I call it) losing my words when speaking, had no energy, motion sickness sex as a newlywed of 2 years (errrrr!) No Thank You, Light & Noise Sensitivity so severe I Flap now and had to quit driving. After Going into that Hole and they just jabbed me for Lithium Levels (nada on anything for seroquel) I A.M’d out and fired him. Went back to old Dr, out of Pocket and he reduced me back 150 mg. I had no side effects at all.

    I then choose to get off this as the plethora of other drugs surely will make up for it and this drug can go back to be used for when I am in a black hole (Risperdal gave me Rx-Induced Parkinson’s x4 )went from 150 mg to 75. I was at 50 but the withdrawal was too much, have lost 15 pounds (gained 60) sweating, Flu like symptoms, MOODINESS, grr (must watch myself) and Motion Sickness. TRYING 50mg FOR 2 DAYS, CAN’T WAIT TO BE FREE. Blessed are the chosen to fight mind battles on this plane, we will be Warriors on the the Next.

  • Jeff March 28, 2015, 8:28 pm

    I had an episode of depression a several years ago and agreed to finally get some help. While in there I noticed the Psychiatrists put EVERYONE on Seroquel. I found it a little strange at the time as I was informed by my Psychiatrist that it was a new drug and does wonders. I mean come on… Everyone in the place was on the same drug? Can anyone say kickbacks? It was a state run facility.

    Took the stuff and didn’t like how I felt, sure didn’t fell any better. Didn’t have any insurance so they were trying to get me on state insurance. When that fell through, they just kicked me out the door and I was on my own. So I ended up quitting Seroquel cold turkey. When the Psychiatrist first prescribed this drug to me I asked him what the side effects were and if there were any withdrawal symptoms. He was honest about the side effects but he flat out told me that there were no withdrawals from it.

    2 days after quitting cold turkey came the withdrawals. I probably had it better than some people but I was still miserable. Never experienced anything like it in my life. The constant nausea, cold sweets, I wanted to bad to commit suicide. And the uncontrollable crying. I couldn’t stop. After that experience I will never trust another doctor again and I know now that I will always be alone in my battle against depression.

    • Bella Page March 31, 2015, 1:16 pm

      **I know now that I will always be alone in my battle against depression.** You aren’t ever alone. We have a world to ourselves.

  • Coral March 27, 2015, 6:31 pm

    I have been on Quetiapine for 3 years now and recently decided I was sick of being tired every morning from it! I started on 400mg but have only been on 200mg for last 2 years so cut down to 100mg for a week no problems, then 50mg for a week. I thought all was OK so stopped completely last Sunday. Had a cold the next day but so did everyone else!

    Wednesday I woke feeling sluggish but after then being in a car for 20 mins started to feel very sick. I thought it was because I had taken some codeine on an empty stomach. It came and went throughout the day but I ate a little so still wasn’t worried. Was sick in car on way home that day too but thought maybe travel sickness! Yesterday my daughter text and suggested it may be the tablets and then before I could look it up I started to feel very strange and my 2 year old was laughing and it was freaking me out (like she was a monster).

    Kept crying too and just felt awful and scared. I called my GP and she said to start taking 50mg again so took that last night. I have had headaches constantly and the nausea comes and goes. I will stick on 50mg as determined to still come off it. Wish I had seen this site first.

  • josh March 24, 2015, 8:16 am

    I was prescribed seroquel for bipolar disorder before being properly diagnosed, my symptoms worsened during the duration of the “treatment” I had abruptly quit taking the drug and I’m paying the price. I’m extremely nervous now and having issues trying to sleep, this in addition to an underlying anxiety makes for one heck of a bad day, so if I could persuade anyone, I would say stay away from this drug. This drug makes you feel as though you are suffering from more problems when you’re on it than before you start it. My opinion is that seroquel is a BAD drug.

    • Shannon Barnes February 7, 2016, 12:51 pm

      I AGREE!! I don’t think it is good for long term use. I can’t walk but now that I’ve been off of it for a couple of weeks, my energy has increased and I’m doing better.

  • Kelly March 18, 2015, 8:57 am

    I had been taking quetiapine for just over 12 months for severe depression 600mg to start with. And after feeling like a zombie I thought enough was enough, I booked an appointment with my GP and explained that I would like to stop them, he advised me to gradually taper from them, but me being me I decided that I wanted off them straight away. I stopped taking them all together. After 3 days I seriously thought I was dying! Cold sweats, thumping headaches, couldn’t concentrate and the itching OMG!

    I couldn’t wait until I could take one that night. Never again would I do that!. Another 12 months and I have gradually tapered from the 600 mg to 25 mg. I am to completely quetiapine free( been 2 months now) I feel great well apart from the odd mild headache in the morning. Eating healthy and exercise has been my only drug throughout this process I have also lost 3 stone that I put on through quetiapine.

  • Afflicted March 11, 2015, 5:09 am

    I started taking Seroquel for anxiety related insomnia. I was being blackmailed by someone I once trusted who was set on destroying my life because I wouldn’t pay up. The first time I tried it I was utterly smashed for a day or two. I gradually needed a higher dose and once I had that dose I could not then function or sleep properly on any less.

    I currently take 1200mg every night and my weight has ballooned to over 130kg. I’ve made three attempts to get off Seroquel and each time I went sleepless for over 4 days straight…NOT A WINK OF SLEEP! I ended up taking it again out of sheer desperation and delirium from lack of sleep. On Seroquel my motor skills are seriously compromised and I constantly bump into walls and doors.

    My new wristwatch is already trashed from contact with surrounding obstacles. Just 24 hours without Seroquel and I start to sneeze and itch without its antihistamine properties. It feels awful and much like having the flu. I really want to get off Seroquel completely but I can’t find a suitable alternative to use as a bridge across to being medication free.

  • Pammie March 6, 2015, 4:22 pm

    4 nights off it now and still feel OK. Mildly anxious yesterday, but got 7 hours sleep last night. No other symptoms really – have been a bit itchy and have a slight mottled looking rash but nothing I can’t handle. Feeling very positive!!

    • Pammie May 12, 2015, 5:31 pm

      That’s 2 and a half months I’ve been off seroquel now and haven’t looked back. Best thing I ever did. Went cold turkey from 25mg and withdrawals were minimal. I am now due to drop from 75mg venlaflaxine to 37mg tomorrow. This will continue for 2 weeks before a further 2 weeks of 37mg every 2nd day. A little nervous but very focused. Best wishes to all going through this! You can do it.

      • Pammie June 4, 2015, 8:11 pm

        Been seroquel free for 3 months and it’s best thing I could have done! Cut my venlafaxine from 75 to 37mg with no issue and I’m now on 37 every other day. Been doing that for a week – slight anxiety but that may have been circumstancial and not due to med withdrawal. I’ve been very lucky and compared to others I’ve got off lightly but feel the need to reassure anyone who is thinking about coming off that not everyone has a terrible experience. Much love.

  • Wendy March 5, 2015, 10:20 pm

    2-1/2 months now and I still have anxiety attacks every day since jumping, even though I’m still taking Xanax. I had only been on 25mg Seroquel too, supposedly a low dose, but the withdrawals are still hitting me hard. I’m even considering giving up and going back on it just to get some release. Maybe it’s better to be in a drugged stupor than live in fear every day. :(

  • roxy March 5, 2015, 5:51 pm

    Thanks for this article, I found it very helpful. I’m off quetiapine for 5 days now and have massive itching of the body. I can handle it, it is just the thing what makes me angry. Sleeping problems are huge, I was ready for it, so I can’t complain. I’m ready to quit and I will. The problem I have now is that I didn’t know that withdrawal effect can last months. I thought it will be maybe a week or two. I took seroquel for 24 years :O how crazy that is? Wow. Good luck to all! Don’t give up, do it and after some time you will congratulate yourself! :) much love.

  • Dee March 5, 2015, 12:19 am

    I have found very few testimonials of people who quit Seroquel who really understand the drug. I took Seroquel for 10 years 150mg each night. After severe edema, explosive weight gain, and onset of diabetes I knew it was time to get off. I tired cold turkey, but that did not go over very well. So I did the gradual taper. I tapered ever 10-12 by 50% until I was down to 12.5mg and then came off it completely.

    Each step down on the taper I experienced a couple days of severe headaches, and insomnia. After day 4 or 5 each step I felt better. I would wait an additional 5 days before stepping down again. I have been off Seroquel for 6 weeks now. The only symptoms I experience are mild headaches at night that I keep in check with Tylenol successfully and major insomnia.

    On Seroquel I would sleep 9-12 hours, since stopping 4-6 hours. Massive change. I am feeling good though. Energized like I was as a teenager and started to exercise. In 6 weeks I am down 15 pounds and I imagine just moving around for the extra 6 hours a day that I don’t sleep is enough to really help that. Good luck to all!

  • Pammie March 3, 2015, 9:12 am

    First night with no seroquel for 5 and half years. Slept from 2:30 am to 6:30 am and actually feel OK! I was only on 25 mg (50 mg few years back for about a year) woke up this morning and even took the dog out at 8 am and walked for over a mile which I’ve never had the energy to do before 12 noon. Very early days, but I’m determined to stay seroquel free! I also take 75mg venlafaxine and hope to come off that next year. Awaiting the horrible withdrawals kicking in… But so far so good!

  • Tina March 2, 2015, 7:55 pm

    I have been on a low dose for insomnia & mood stability, and I’ve been decreasing my dosage by 25mg every 1 1/2 months. Every time I reduce by 25mg it’s awful. I’m on day 7 of taking only 25mg. Blurred vision, dizziness, nausea, and aggitation every day. I cannot wait for this to finally be over. DO NOT TAPER TOO QUICKLY – it’s still awful doing it slowly. I have barely maintained my life just due to the side effects of withdrawl. Just do it slow and steady. Very slow.

  • RWA March 2, 2015, 5:18 pm

    I’ve been on Seroquel XR 50mg for about 5 months as an adjunct to my 60mg of Cymbalta for anxiety and depression. My P-doc told me I no longer needed Seroquel any longer as I have stabilized and am doing well. I haven’t had any Seroquel for 3 days now, and my sleep is patchy at best. I can fall asleep but wake up many times at night. I also feel quite anxious, and as tho the depression is creeping back.

  • Maureen Rush March 2, 2015, 2:55 pm

    Thank goodness that I have found this website. I actually thought I was going completely mad! Suffice to say, I have been suffering intermittently with depression. All circumstance based. My last bout was three years ago. It was severe. I was prescribed Quetiapine. I noticed a weight gain almost immediately. I was on 250mg,then 150mg gradually reducing to 50mg. My Doctor knows very little about Quetiapine. I have had to inform her of the side effects, withdrawal symptoms, etc.

    I have reduced my dosage to 25mg. I feel like I have been hit by a train. I’m mentally, physically exhausted, flu like symptoms, severe stomach pains, legs aching. Basically, I feel like hell. But I am determined. Has anyone any advice on long it took to lose the increased weight. I am aware that this awful drug interferes with your metabolism. I jog, walk as well as Teach SEN children so always on the go. But struggle to lose 1 lb a month! Thanks for listening.

  • Karen March 2, 2015, 12:45 pm

    I’ve been reading through the comments and while some of them are similar the worst problems I’m having with cutting both fast and slow release are intense food cravings and unbearable restlessness. It’s not a panic attack, more of a constant internal churning which makes it difficult to work or study, and resting, sleeping or lying down bring no relief. Has anyone experienced this side effect and what helps for it? I’ve been self medicating with benzos but the amount I have got only helps take the edge off. I feel like I want to scratch my insides out.

  • Prug February 27, 2015, 12:55 am

    I first started taking seroquel about 3 years ago – went up to 300mg for about 6 months but found the fatigue was too much to bear seeing as I was entering my last year of university. I have been able to taper it down to 75mg for the past 9 months and have begun the 50mg last week. The main reason for trying to get off seroquel was to stop the dependence on it for helping me sleep, make myself more aware and active during the day, lose weight (I’ve put on about 30kg over the years), and finally to cut down the amount of meds I’m taking (5 with the seroquel).

    I didn’t have any side effects tapering down from the higher dose, but transition to 50mg has been hell. I am sweating liters a day, constantly feel like throwing up, nausea, jaw grinding and headaches – tension, hypersensitivity to light and sound, anxiety, rapid heartbeat. Sleep has been okay but not refreshing. Although I keep thinking of upping the dose back to 75, I keep telling myself that the symptoms will pass. I think the 2 major pluses have been my energy increase and finally no recurrence of the psychotic symptoms that were present when I started the meds.

    I know that seroquel was definitely needed in my recovery but I am of the opinion that it shouldn’t be prescribed long term – I became way too dependent on it, which is something I have always promised myself I would never become (use the meds as an aid, but not a crutch on the walk to becoming healthy). I am also hoping that my libido will return soon…for both my partner and my own sake.

    • Tina March 2, 2015, 7:58 pm

      Yup – 75mg to 50mg was exactly the same for me. My energy has steady increased though – so that keeps me going. Stick with it. I find 1 & 1/2 to 2 months after a decrease before all the side effects are gone.

  • Pedro February 25, 2015, 12:56 am

    I was placed on Seroquel at a very young age (8 or so) and was on it until I turned 18. I was neither schizophrenic or bipolar, my grandma just wanted to use it to get a disability check. I don’t know what dosage I started off on, but I know that it was at 200mg when I stopped. I tapered off and felt fine for about 7 months, but suddenly woke up with anxiety followed by depression; my vision got worse; my speech started to slur a bit; I easily became light headed and my memory got worse.

    I always feel zoned out and spacey, like I’m not really there but I can still function. Things that were simple before seem a little more difficult and, a few days ago, I started having delusions. Is it weird for that stuff to happen so long after stopping? Or could being on it at such a young age, for practically no reason, have messed me up? Please let me know if you know anything. My family is spending a lot of money on my doctor visits and we can’t seem to find any other causes. Thanks.

  • Wendy February 22, 2015, 2:40 am

    Update at two months off Seroquel. The dizziness and nausea are much better now, but I still have daily anxiety, especially at the end of the day, as well as flu-like muscle aches. Tinnitus is bad as usual. Fatigue waves come and go, worse in the later half of the day.

    • Giffordw August 24, 2015, 3:58 am

      Tinnitus is a side effect of Seroquel. Supposedly it is permanent. I have it too. Likely caused by being on Seroquel for 10 years at 100-350 mg/day.

  • Herbie February 21, 2015, 1:26 am

    Back with an update. Been three months or so now of zero Seroquel, and I think I tapered down for close to three months. Panic attacks, I think I mentioned; they were gone almost immediately once I realized they were chemically caused. I don’t think the itching went on much longer than my last post, or I may have mentioned it was going away already. Runny nose, that went on for about another month after last post. Seems to run on a cycle though; every week or two it comes back, a little less severe than before.

    Still can’t sleep very well. Probably two nights out of three, I either lay awake for hours, or wake up after just one or two hours, and can’t fall back to sleep again. That does seem to be getting better, and maybe closer to two bad nights in four, and certainly the sleep periods are lengthening. But I am somewhat mildly depressed nearly all time. And have an extreme lack of energy. I’ve suffered from depression for most of my life, and usually it’s more extreme than this.

    So I can handle it fairly well. But this has been going on for a long time, and coupled w the lack of energy; I don’t get hardly anything done. At all.
    There are good days. Perhaps one in seven is decent, and one in 14 is great. But it’s rough the rest. I’m not suicidal. It sure would take a lot for me to get to that point. But I doubt that I will get much accomplished in the next three to even six months. But I do have dreams and goals, which if I don’t soon begin progress on, yes; life will look pretty bleak.

    My head is a little clearer. A little. And, oddly since I was taking Seroquel largely for social anxiety, my confidence in self-value has gone up quite a bit! I think that’s because I believe people are interacting with who I am, instead of who a drug makes me become, so I have less to hide or be ashamed of. It is already worth it, getting that satanic crap out of my body. Probably in another three to six months, I can begin accomplishing all that I missed out on while being foggy for years! Be well everyone!

  • David B February 20, 2015, 7:58 pm

    Seroquel was prescribed by my family doctor to help lower my anxiety, depression and OCD in combination with other drugs. But my Psychiatrist wants me off of it. Therefore I am weaning off, and it has been hellish. I feel suicidal and depressed. I maxed out at only 150mg daily, so I feel fortunate that I am on a low dose compared to other people. I feel empathy for people who are weaning off. I am down to 75mg and it is very hard to cope, but I am getting through it day by day.

    • Tina March 2, 2015, 8:03 pm

      I feel ya. I had the 150mg max dose to, and it’s been awful. I have no clue how higher dosed people do it. 75 to 50 was hardest for me. I don’t decrease more until I feel completely OK. 150 to 100, 100 to 75 was OK – took about a month each- 75-50 took almost 2 months. I just didnt want to decrease again when i was still feeling crappy. Im on day 7 of 25mg, the side effects are different & much more manageable. Good luck! Keep working on it. I feel like it’s a huge deal to go through this.

  • francesca February 13, 2015, 4:10 pm

    Hi, I have been on 150mg quetiapine for 8 years. I recently found out that I am pregnant and was told to reduce my tablet to 100mgs for 3 days, 50mgs for 3 days then nothing! I have not slept for 2 days, I have really bad itching, stomach cramps and headaches. My psychiatrist says that these are not symptoms of withdrawal – that the drug will be out of my system now after 8 days. She has made me feel worse, like it is all in my head – I am sick since stopping taking my meds, but she said that is because I’m pregnant… I wasn’t sick before. I am really struggling and feel no-one will help me. My psychiatrist also said that a quetiapine is not addictive.

    • Giffordw August 25, 2015, 2:21 am

      Time to get another psyc. Before you see him or make an appointment ask if he is aware that Seroquel has severe withdrawal symptoms.

  • Mike February 11, 2015, 5:45 pm

    My friend was put on Seroquel and Celexa for anxiety, depression and insomnia. He felt slow and confused while on it. He tapered and than quit. First the side effects were irritability and moodiness, which he could cope with. Then came the extreme insomnia followed by mania and psychosis. He says he’s fine and just undergoing a transformation. I’m hoping it will eventually subside. I’m at a lost as to what to do. I’m anti-drug, but at first I thought it helped but after seeing the results, clearly this drug is being over prescribed for patients who have other avenues.

  • Marie February 11, 2015, 4:52 am

    Nineteen years ago, as I went throughout menopause, I had a bout with run-of-the-mill depression. Had a bad reaction to first antidepressant – kept me awake for 2 weeks – no sleep at which resulted in sleep-deprived psychosis and my first hospitalization. Each new psych drug had a side effect so the doctors (I”m on my 6th psychiatrist) would add a drug for the side effect. Of course that drug had a side effect so we just added another one. At one time I was on 10 psych meds in addition to monthly electroshock treatments.

    Yes, just like in One Flew Over The Cuckoo’s Nest. 10 years on Seroquel – gained 100+ pounds which I consider excessive. No amount of diet, exercise would stop the gain. Was constantly sleepy – can fall asleep from just sitting for less that 15 minutes – after sleeping 8-10 hours per night. Have reduced Seroquel from 400 to 300 to 200 but now have quit cold turkey. Using Ambien for sleeping and Benedril for itching. Had only one headache, used Tylenol.

    Biggest problem in horrible diarrhea; my bottom is sore and I’ve had a couple of accidents. I’ve had some brain zaps but they have not been as bad as from quitting Cymbalta. And the dizziest I ever was was with quitting Paxil. Been exercising daily, eating lots of fruits and vegetables, meditating and spending lots of time cuddling with my kitty cat. Best part of all after being zonked out for all those years is the feeling of being wide awake – all day long. And after only 4 days I’ve lost 6 pounds. I am going to do this. All of these drugs are bad.

  • Jim February 8, 2015, 4:26 am

    I have been taking Seroquel for over 12 years. I am 64 years old and feel the need to get off this drug ASAP. I have tried a few times only going back because the symptoms were too much. (Withdrawal symptoms and not Psychiatric symptoms) I have had a few drug dependencies in my years including, Valium, Heroin, Alcohol to name the difficult ones to quit and having “true addiction” qualities. Seroquel was and is a very difficult drug to quit with so many withdrawal symptoms… making it one of the worst experiences I have had with getting off drugs, and meds.

    I an still trying. I am now tapering 0-20 mg/month with my goal of off Seroquel by the end of 2015. It is now February 7 and I am at about 120mg/month now and feel I need all of that time to minimize the pain of “Protracted Withdrawal Syndrome”, or Post-Acute-Withdrawal Syndrome aka- PAWS. I tell anybody I know who is taking Seroquel to get off it as soon as you can. It is not a good medication for what many Psychiatrists and MD are prescribing it for. It is not a sleep aid. Well I suppose it is but should not be used for so many off label symptoms.

    I have found that most proscribing doctors are not sufficiently informed about what it takes to get stop this med and are prescribing too easily. I am mad as hell about not having “informed consent” back 12 years ago. The informed consent process is becoming more prevalent as time goes on. I was trying to get off addicting drugs not start a long term relationship with another miserable drug to quit down the road. Anyway my advice is get off it if you can, lower the dose if you can. You can either resign yourself to taking this med forever, or begin the fight to get off it. It is your choice. Good luck.

    • Tina March 2, 2015, 8:07 pm

      I wanted something for insomnia, so my doc gave me this at 150 mg. When I started sleeping way better, months and months later, I wanted to decrease to 100 mg. He said no, because I was on it for insomnia and MOOD STABILIZING. What? He never even told me that. I feel so mislead. (Did it on my own time and now down to 25 mg – feeling great).

  • justin c February 3, 2015, 5:32 pm

    I’m trying to come off seroquel now after almost ten years. It’s really bad. I can’t stop throwing up, can’t eat, can’t sleep, and I feel like I’m going to die. I don’t know if I can handle this for 3 months. I kill myself by then. I don’t know what to do. Detox facilities won’t accept me. I never thought I would have to go to the streets for this medicine.

    • jim February 8, 2015, 4:33 am

      I know exactly what you mean. My comments follow. I tried to get into a Detox facilities too but the only ones who would address it were “cash only” and a whole lot of it. Keep the faith and keep in contact with medical professionals. Good luck. It can be done. Keep trying to get some kind of help with it. I know it really sucks, I have tried and failed. Felt awful, like you described. I am starting a long term tapering of 5-10 mg/month. I think that may have to be lowered so as not to feel too sick and function day to day. Again, good luck.

  • Deb January 29, 2015, 11:25 am

    Interesting to read all the issues people are having withdrawing from Seroquel (quetiapine). I work with a population of addicts and mental health clients. I have been on Seroquel XR for a number of years with a max dose at one time of 900 mg. I gained a horrific amount of weight, have trouble swallowing to the point of not being able to unless I drink something and things go down with a great deal of discomfort.

    I finally reduced that over time to 200mg. I again went down to 150mg. I would like to further reduce that and eventually get off the stuff. Recently I had the discomfort of finding out what happens when you quit cold turkey but in my case it was missed doses for 48 hrs. I should by now recognize those symptoms as they will occur if I am late taking it as I have to vary the times because of working graveyard shifts. I started with shivering, then sweating profusely and eventually the nausea started.

    I know I will have to go at this over a period of time for sure because of work, something I can ill afford to miss. The other realization is that the withdrawal symptoms are the same as what my clients experience when withdrawing from any street drug. Made me realize just how much this poison is really affecting my system to experience a hard core drug addicts withdrawal symptoms. Please, if you are trying to quit, do it slowly!

  • aylad39 January 28, 2015, 8:32 pm

    Has anyone experienced extreme hunger? I’ve had the nausea, vomiting, insomnia, exhaustion and now today I’m starving. I’ve been eating well all day and still my stomach is growling. I have been tapering down from 600mg for about a year because I couldn’t take the exhaustion. I also experience memory loss and decreased cognitive function, but the fatigue was the worst. Anyway, I have been doing some searching online and I can’t find anything about extreme hunger but going off of the Seroquel is the only thing I can link it to. Thanks in advance for any input.

    • ktlady July 15, 2015, 2:24 pm

      I quit Seroquel years ago, and I experienced the extreme hunger you described. It also came along with a whole host of stomach/digestion problems but the hunger thing was the weirdest part. I had upper GI workup done and they couldn’t find anything to explain the symptoms I was having. What I think now is that it is linked to overall increased anxiety.

      After coming off seroquel my anxiety skyrocketed for years, only just now (8 years later) getting somewhat under control. My stomach is doing much better. My advice is to try not to listen to the hunger. Put yourself on a very regular eating schedule (3 healthy meals of breakfast, lunch, dinner at set daily times) and don’t snack in between. It will be hard since you are feeling hungry, but I think giving into that sensation makes the feedback loop worse.

      Make sure if you can to get enough sleep as I notice the less sleep I get the more fake-hungry (hungry even after eating) I feel. Only when I started scheduling my eating and not giving into to snacks and cravings did the constant hunger abate. Also try to do relaxing things to distract yourself when feeling hunger, whether it’s reading, watching your favorite movie, talking to someone you love, doing some art, taking a bath, whatever. Hope you’re not still having that issue but if you are, try some of those suggestions. Can’t hurt, might help!

  • Olivier Sw January 27, 2015, 2:18 pm

    Psychiatrists keep delivering Seroquel simply because… they don’t use it on themselves. Also because, Seroquel does help on certain major conditions (schizophrenia). Side effects? Shrinks are not interested: “it fluctuates from a person to the other”… Which is right, but also closes any debate. I have been on Seroquel for 8 years now and I have decided to taper off. I have been up to 300 mg then 200 mg for two years (in the evening) and I have now reached 175 mg.

    I will stick to that for a month and then reach 150 mg. Then I’ll stop for a further 2 monthes and hopefully I’ll look for 125 mg. The golden rule is 25 mg as a unit. I don’t think I will ever be capable of withdrawing totally from the drug because of sleep deprivation. Anyway NEVER quit cold turkey especially if you’ve been on it for many years. Your brain might never heal itself properly. Watch out for this beast…

    • Ricky April 15, 2016, 6:53 pm

      Have you suffered any muscle spasms? I have been on Seroquel for 8 years myself. Frankly, I am emotionally numb. I want to get off of it.

    • BeenthereDonethat July 14, 2016, 6:25 pm

      What makes you think your brain won’t heal properly if you go cold turkey? Do you have some good professional advice for this view, or is it just a hunch off the top of your head?

  • Susan January 21, 2015, 5:15 pm

    I have been on Seroquel for 4 years. I was up to 400mg and wanted to slowly go off but then I got a new insurance policy and its been a week and they haven’t approved it yet so I’m going through horrible withdrawal and lost 5lbs in a week. Not that I’m complaining of weight loss, but it’s the nausea and the lack of sleep that’s horrible. I wouldn’t wish this withdrawal on my worst enemy. My dr just gave me two meds so I can sleep so last night was the first night I had a few hours of sleep. But as the day goes on I feel like I still haven’t slept. I want this feeling to go away so bad.

  • David January 15, 2015, 10:00 am

    Dave’s 2nd Video Update:
    Three Months off Antidepressants and Antipsychotics.

    First Video Link is in the Description.

    Wishing you all well in whatever challengers you chose to take on.

  • Susan January 12, 2015, 11:01 pm

    I was on 600mg of Seroquel and we decided to switch me to Latuda hoping this would work better. I have been very slowly tapering down the seroquel while increasing the Latuda. Since the last decrease from 200mg to 100mg I can’t stand to be in my own body. I am agitated and anxious all the time. My sleep is erratic. Noises and lights bother me like nails on a chalk board. My heart is racing and I feel like things are surreal sometimes.

    I got so anxious one evening I ended up having to take anxiety meds twice and I rarely have to take them. I’m shaking and I can’t stand to be around anyone. I live with my daughter and son-in-law so that’s not really possible most of the time. I see my pdoc in a few days but does anyone have experience with how long this lasts or anything that has helped. This feeling of wanting to crawl out of my skin is just intolerable.

  • Ms. Karma January 12, 2015, 4:11 pm

    Hello again, I posted some time ago regarding tapering off Quetiapine. About two weeks ago i finally finished my last 50mg tablet (down from a peak dosage of 800mg I believe). Although I had already read about it, I wasn’t ready for the weird stuff this has done to my sleep. Not only has it done what it says above, disrupted sleep pattern, but I am starting to remember all of my dreams again.

    This is really odd for me since it’s normally a rarity, or has been whilst on the drug. The trouble is that I’m tired, really tired, but when I sleep, I wake up roughly every hour to hour and a half. It’s REALLY annoying. I’m hoping it will pass. And despite having two other drugs helping with anxiety and mood stabilizing, I have this weird feeling of feeling ‘exposed’, I suppose it’s a combination of extra anxiety and the effect above of being more sensitive to light.

    Another effect which I didn’t quite expect was that my period has suddenly re-started, for context I hadn’t had one for over two years. Annoyingly, it’s been going on for nearly 3 weeks now, which hasn’t helped my general mood, and after not having one for so long, I don’t quite know how to deal with it! I guess this means my body is trying to start functioning again, lol.

  • R January 12, 2015, 2:40 pm

    I am so glad to have found this. I was on Seroquel (100 mg) for 1.5 years. I was diagnosed with major depression and anxiety after learning some thing about my now ex-husband. I did have a breakdown and spent two weeks hospitalized. The Seroquel was given for insomnia, in addition to Celexa and Xanax. I stopped taking the Seroquel gradually over a two week period and could not understand where my symptoms were coming from. I have muscle pains, a constant runny nose, and a low grade headache that won’t go away.

    I have had these since stopping the Seroquel completely and am wondering how long they are going to last. I was working out on a regular basis but stopped a week ago because I thought I was getting sick. It appears I am not sick, I am withdrawing. Wow, I had no idea the power this drug had. While I may have needed it for a while, I am glad I am off and will continue to put up with these symptoms until they let up. Thank you for this forum.

  • leann January 7, 2015, 5:55 am

    I’ve been taking Seroquel consistently for 4 months, started at 150 mg due to bad insomnia and depression. Went as high as 225mg. My psychiatrist now has me on a gradual taper since I’m a whole lot better. I went from 75 mg to 25 mg in a month. I tapered about every week to two weeks in 10 to 12 mg increments. The withdrawal symptoms were intense but I avoided the more serious withdrawal symptoms because I didn’t rush my taper. You have to take it slow. My psychiatrist reminded me that there is no rush.

    The symptoms I experience are extreme fatigue, stomach pain, diarrhea, heart palpitations, and tiredness. That’s about it, I avoided all the other withdrawal symptoms. Just do your best to be productive, eat very healthy, whole foods only, and drink lots of water. Pray a lot, and get support. I’m so excited I’m finally on my last dose. I should be med free in a couple weeks. So the med should be out of my system by the 2 1/2 month mark. Try to keep your head up. We are a lot stronger than we think :)

  • Victoria January 4, 2015, 11:37 pm

    Hi everyone! I quit cold turkey ten days ago, after about 12 months of taking 400mg a night in conjunction with venlaflaxine for major depression and personality disorder. I feel physically well for the most part, more energized and positive about quitting (even though it’s against the advice of my GP). The thing that I am struggling with the most is nausea and being unable to eat much. This is a symptom that at the moment, isn’t too bad to cope with.

    I am also feeling as if I am getting a cold and am really itchy EVERYWHERE. If you are thinking of quitting then I suppose it’s important to remember that our bodies are all different. But I hope it brings someone some comfort in knowing that I am not struggling too much and the withdrawal symptoms so far, are manageable.

  • Wendy January 3, 2015, 5:55 pm

    I was on 50mg Seroquel for a year for insomnia, then reduced it to 25mg a few months ago, then quit it entirely two weeks ago. I switched to taking Lunesta to sleep, but I still only get about 6 hours before I wake up. I really need closer to 8 most nights to feel ok. I felt ok for three days after quitting, then got hit with dizziness and nausea, with occasional body aches and chills. The dizziness is the worst, it has lasted non-stop for two weeks. I have an inner ear condition that causes dizziness, but I was pretty stable until two weeks ago.

    I don’t know if cedar season has triggered the dizziness, or if it was triggered by the Seroquel. I was never on more than 50mg, and was down to 25mg for a few months before quitting, so I’m not sure if even coming off a low dose can cause these ongoing symptoms for weeks. I was on it for a pretty long time though. I hope this clears up in a few weeks, I really don’t want to feel this way for three months like the article says above.

  • Justin January 3, 2015, 1:29 pm

    I have been on seroquel for 4 years. Originally prescribed XR, and switched to non-extended about 9 months into treatment. Holy weight gain Batman. Also, although I enjoyed the sleep benefit of the med, I felt like I had a small window in every day when I wasn’t negatively impacted by the drug. (Nighttime and morning blurs from the sedation). I was on 100 mg for awhile and then decided (on my own) to cut the 100 in half and take 50. I wasn’t doing that to ween myself off. I did that BC I found that I got some of the sleep benefit, and didn’t have such a difficult time waking up (physically and mentally) in the morning. 2 weeks ago, I decided I didn’t want to take the drug anymore so I stopped.

    Again, I was only taking 50mg at night so my Dr insisted I was not receiving any therapeutic benefit from the med, and was only getting the benefit of its side effect, sleep. 2 weeks in, and I feel great. I told my wife I was stopping and to please be upfront and honest with me regarding any moods changes or negative impact, and we both agree fortunately I’ve had none except for the insomnia. I cannot sleep. I can’t fall asleep. I cannot day asleep. All day long I’m completely fine. My wife is in the field, so if I was struggling with anything mental she would call me out on it, so I’m pretty confident when I say I’m fine, I’m fine. The only problem is the lack of sleep.

    Additionally, my allergy symptoms (runny nose, sneezing, watery eyes) are present now at night only. No itching as others have mentioned, just the name and eyes. I can’t take my normal allergy med zyrtec-d at night BC that would contribute to my insomnia. I tried taking a sleep aid, zzzquil and it hasn’t helped.. I don’t want to go on another prescription that I could get dependant on just to help me be less dependent on another drug. I am not a guy that wants to remove drugs and go holistic or anything. I just don’t like Seroquel. Can anyone offer insight? I know anything is possible, but could my onset of allergies which were pretty controlled while on seroquel be related to discontinuing? Again, it’s only at night, no sneezing or anything during the day. Thanks!

  • Miss R January 1, 2015, 12:10 pm

    I’ve stopped less than 4 days. I was on 50mg on seroquel and I thought I was going through menopause. My withdrawls at this time are vomiting, stomach pains, dizziness, lots of night and day sweats! Thank you all for this information.

  • Allison December 31, 2014, 8:53 pm

    Tonight is my last 25mg of Seroquel, down over a few months from 300mg. I don’t have nausea or itchiness. But def insomnia and depression – however I have some reasons to be legit depressed. My daughters have had the flu the past 6 days. I don’t have the resources or $$ for any more pills, so I am kind of forced into dealing with whatever comes my way. I have herbs, support of friends, etc. But wondering if I am kidding myself that this is as bad as it will get?

  • Donna December 31, 2014, 6:32 pm

    I have been taking Seroquel for about 5 years. I was on 50 mg for some time and then decided to drop to 25. I didn’t have any horrible withdrawal symptoms. Then I tried cutting down to 12.5 mg twice and both times I had such horrible nausea and difficulty concentrating that I went back to 25 mg. I am a college professor and feel that I can’t go through withdrawal until I have some time off like this summer. It is so good to know that others have experienced withdrawal symptoms similar to mine. I REALLY want to be off of this drug! Thanks to everyone who has shared experiences with Seroquel withdrawal. You really encouraged me!!

  • Allison December 30, 2014, 3:02 am

    I have been on 300mg of Seroquel for about 5 years. For the last three months I have been tapering from 200mg to 100mg to 50mg down t0 25mg the last two weeks. I have begun feeling withdrawal already and have two 25mg left to take. The worst is ahead of me. I was put on this horrible drug because I was “depressed” and had insomnia — I had two babies, worked full time, my then-husband was having affairs and he physically and verbally abused me. My two daughters and I have been stuck home with the flu, and I hope people just think I keep having the flu.

    I am scared, but enjoy seeing my thoughts more in color already. I never put on weight with this but my feelings were cut off. I am losing weight already, and probably shouldn’t much more. But I can’t eat. Dave, your posts have inspired me. I work for a Doctor of Oriental Medicine and Acupuncturist so I have been given a full arsenal of herbs and healing. I hope I am one of the lucky ones and with the help I have don’t feel so horrible over the next few weeks to months. I’ll keep you posted. It’s with gratitude for all who posted.

    • M.b September 30, 2016, 3:14 pm

      Best of luck. I’m down to 12.5 mg. It’s tough.

  • Dave December 27, 2014, 5:38 am

    ITCHING YES! – I believe you – some doctors won’t. My doctor refused to believe that seroquel had anything to do with the itchiness. I knew better – His refusal to hear me out and or regard my own research on the internet as pointless was why I never told him when I decided to come off it. I think some doctors are just plain lazy and or rutted in their ways. At lease I find the majority of them within the welfare system to be very much this way. Itching was a major pain with this drug for me.

  • Lorena Martinez December 24, 2014, 2:01 am

    I have been taking Seroquel 150mg at night for about 6 months. I decided to get off it cold turkey not remembering that you are supposed to taper off antipsychotics because they’re so strong. After the second night, the following morning I started feeling nauseous and like I had a cold, and about an hour layer felt do miserable I had to lie down. I had had insomnia the whole night before, and I realized I had to take half for the horrible feeling of nausea to go away.

    I took half and felt better in a half hour and them slept for four hours. I decided to take 75mg a night for the following week and then stop again, which was a few days ago. I have had nonstop nausea since then, which I have been relieving with pepto bus mom chewables throughout the day, but I am weary of overusing them. Does anyone know how to deal with the nausea?

  • L December 21, 2014, 5:34 pm

    I’m joining the fight! I’ve been on quetiapine for 1.5 years. First, I was on 100 mg. Then, 600 mg for a few weeks. I have been on 100 – 200 mg for a few months. I have attempted to leave off this drug cold turkey a few times, but the itchiness is INSANE and also insomnia. I have taken 50 mg for two nights. Bit harder to sleep, but feeling OK. I want to avoid the itchiness. I think sleep will be a difficulty for me. I will go down to 25 mg soon. Good luck everyone.

    • L December 31, 2014, 9:56 am

      I have now been on 25 mg for 4 or 5 days. I am doing OK. I feel physically quite bad; a bit like I have a cold coming on. My brain also feels a bit odd, attributable to a general “I feel slightly ill” feeling. However, I can think quite clearly about things. Like others here, I have been trying to exercise every day since dropping, to give myself the best chances of survival (and of sleeping). On 25, my sleep has been a bit dodgy sometimes, but I force myself to go to the bed at a similar time every night (usually 11:30 – 12).

      This morning, actually I woke up at 7:50 and then went back to sleep until 9 AM; I think I went to bed at 11 PM… I think this might be attributable to my “I feel slightly ill” feeling, as I tend to try to sleep off colds. However, I was also walking outside for an unusual amount of time yesterday, so might have been more tired. I managed to get hold of a prescription for 14 more days of 25 mg. I do not feel ready to come off just yet, as I have important commitments coming up and I do not feel secure in my sleeping habits on 25 mg yet. When I do, I will drop to 0 mg and update. No itchiness. Head hurts, but think it is a cold coming on a bit. Trying to eat regularly, exercise every day and stay healthy. We can do it!

  • Laura December 14, 2014, 7:42 pm

    I was on 300 mg Seroquel XR for about a month and hated the way it made me feel; irritated, sad, and I had no sex drive along with gaining 10 pounds within the first two weeks. Last weekend I stopped taking it altogether and suddenly I’ve been constantly nauseous and I just want to cry all the time because it’s so bad. I went to the hospital and they said I had the flu and did blood work, so I know I’m not pregnant. But I didn’t mention I had been on the Seroquel at all. Is it possible I am having withdrawal symptoms even though I wasn’t on it long? If so, how long is this going to last? I feel like hell

    • Megan December 22, 2014, 2:52 am

      Yes, you have to titrate off it and very slowly if you don’t have doctor supervision. I was on 600mg/day and a different psychiatrist titrated me down to 300mg/day. I have cut a third off and will take 200mg/day for three weeks. Then cut another third off and do 100mg/day for three weeks, then taking 50mg/day until it runs out (I’d say a month). Slower is better and yes, the crying and insomnia is most likely withdrawal. These pills are dangerous and they have our brains and bodies hooked so to deny them these chemicals suddenly, is not a good idea. Take your time. No rush.

      • BeenthereDonethat July 14, 2016, 6:05 pm

        They thought you had the flu???? Wow! What’s wrong with those people! Of course you were withdrawing! Those are classic symptoms of Seroquel withdrawal, especially the constant nausea! You were on a really high dose so it probably doesn’t take long to get to a point where withdrawal becomes terrible.

        I’ve been on 200mg for a couple years and I came off it for 4 days and wanted to die! I had most all of the symptoms except itching. Nausea seems to be the most common complaint, I had that so bad, couldn’t even look at food. Had bad sinus problems (evidently Seroquel is a great antihistamine!), slept all day and night with bad sweating, vomited, etc.

        So, don’t even question if it was Seroquel withdrawal, it was! What is amazing is that you can have the same terrible withdrawal with 25mg as you do with 400mg! And all the terrible symptoms can last a year after quitting! I don’t see myself ever coming off this drug. I hope it doesn’t kill me! I am going to try to taper off, although that seems kind of hopeless, too.

        One thing I would like to add to the discussion is that I noticed one thing. After being off the drug for 4 days, and going through all that hell of sleeping all day and night, and then getting where I couldn’t sleep I took a third of my regular dose of what I usually take and I was out like a light! Seroquel was losing it’s effect at helping me sleep, and this was like when I first took Seroquel and would be out like a light 10 minutes after taking it at night and would basically sleep through the night 8 hours (in this case it was more like 10-11 because I was depleted).

  • Lynn December 13, 2014, 6:30 pm

    Everyone’s comments have really given me hope that I can get off these meds. I have been taking seroquel for probably about 9 or 10 years, and Zoloft on and off during that time period. I’m currently taking 400 mg of seroquel. I have been down to 300mg but am more comfortable on 400. The last time my doctor tried to stop the meds it didn’t turn out well at all.

    I felt awful and my bipolar symptoms came back right away so I went right back on the meds. I really think I was weaned off way to fast. I’m willing to take a year or two to get off them if that would be easier on my body. Will I still have as bad of withdraw symptoms if I do it very slowly? I’ve been having a lot of side affects. I just turned 23 and I really am afraid this medicine will kill me. I want my life back!

    • Dave December 14, 2014, 8:57 am

      Hi Lynn, I am no doctor, and by the sounds of it you might understand that whilst many people will advise “Check with your doctor first”, that not every thing these professional say or do it correct and or guaranteed. Coming off anything that has been relied on heavily for years will often require a few attempts, so please don’t be disheartened with less than favorable results.

      MY ADVICE – 1st … Make a determined decision that sets like concrete. That way if you do decide something, you will not be so easily put off with the stigma often faced by those who are used to being seen in one light. Often Doctors and those closet to us are not as supporting as we would like when making such changes. Letting others know that you have thought long and hard about your decision to choose another method may ease the concerns of those whom may be resistant to the changes you may wish to make.

      Explain to them that you are aware of the dangers and wish to tapper off or whatever it is that you feel comfortable with trying various other copping strategies that you have researched and so on. Provide an Outline and present a plan to anyone wondering what you are doing and or thinking. Tapering off is pretty much the wise way to go. “HOW MUCH & HOW FAST” I guess your looking to that already. Things to consider are your own past experiences. No one knows your body better than you.

      You mentioned you struggled going from 400 to 300 … so why not just drop it to 350 … and see how that feels for starters. You can even drop in to 375 and go down on 25 lots. Remain proactive in your approach by keeping a small record/diary/journal … I have been using this place as well as another. Understanding the physical symptoms that can occur when coming off takes away fear of not knowing what it happening – when withdrawals and resultant side effects take place.

      Adopt the alternative strategies that you have read about: Outdoor Exposure, Exercise, Healthy Eating, Supplements, Self Hypnosis, Music, Hobbies, Creating & Regulating Routine, Psychotherapy/Therapist. Make a list of what works for you … include these in your place so when asked “Then what is your alternative?” Refer to your list – Take it with you to whatever appointments and sell your plan to those who are less encouraging as others – show them that it’s not an easy route, but that you are more than prepared to take it on and that you will in all likelyhood be the better for it.

      Just be careful of replacing one medication for another – in all likely hood you may very well end up in the same position. There is nothing wrong with taking something to assist coming off, however what you choose to take or are “recommended” (even the doctors) is not always explained very well in terms of underlying complication and “other People” rarely care to take all the variable that relate to you personally into consideration.

      Sorry for the long winded reply – I just wanted to encourage you that whilst it sounds like a huge effort … well … IT IS … the fact remain that you and other like yourself CAN DO IT! Just be sure to make the decision yours! Set is in concrete and Have a Plan! – learn your plan and learn it well … so that you can tell others. Be prepared to be met with resistance but gravitate towards those who encourage. Understand that you are not your label!

      Understanding that provides a wealth of insight, however its something that only comes from after taking the first few steps into the unknown; but KNOW THAT YOU CAN DO IT, and you will soon begin to grow in confidence and embrace whatever follows … mania becomes more your passion, instead of what others may term as negative … you will begin to see yourself in a new light and others who thought only one way existed, will also be more open to seeing in a new light as well. Wishing you all the best. -Dave.

  • Ms. Karma December 2, 2014, 2:35 pm

    Hello, thought I would share my experience, which fortunately for me is not so bad. Perhaps encouragement that it isn’t always awful coming off Quetiapine? I am bipolar. I was on 800mg of Quetiapine for around 18 months or so. I’ve been coming off it for some time – I went down to 300mg, I think early this year? Then in the summer I was told by my psych Dr that I could come off it, reducing by 50mg each month. I’m now on the penultimate month, on my 50mg.

    I’m definitely feeling better, but the reason I was on it was because I was manic, and I’m scared I’ll end up there again and back in the hospital again. I think I’m doing OK though. I am kind of irritable, but I put it down to the fact my energy levels are going back up! I don’t feel nearly as tired in the daytime any more. Obviously, I still have to come off it altogether, but I’m quite big and weighty, so I figure this dosage is like having nothing anyway.

    What I would say is that I am also having Pregabalin (for general anxiety) and Lithium. So I do have that safety net of a mood stabilizer and something to help anxiety. I do find that I have the desire to stay up late again, which could be tricky as that’s what got me manic in the first place, but I just have to remind myself that I’m still on something to help. If you are considering coming off something cold turkey, don’t! I’ve done that with a few things, a long time ago, and it NEVER ends well, trust me!

  • Dave December 1, 2014, 10:03 pm

    Hey guys, I’m not on 12 weeks “Off” yet, but wanted to encourage some of you and also reiterate what Kathie said about coming off of this Cold Turkey. “Don’t do it.”

    -Hi Julia – I was too was taking Seroquel for extreme anxiety and depression. The obesity that followed for me has been quite debilitating. I did have to up my dose as I too, tried coming off abruptly, but without success. I wish you the very best and hope your able to record some of your efforts in coming off.

    -Hi Herbie – Was good reading your experiences there. I hope you are getting or at least will find some restful moments soon enough. I did a bit of reading online in relation to hive like symptoms and Seroquel/quitpine. There defiantly seems to be an issue with histamine imbalances which varies from person to person based on this or that variable. I was majorly one of them. I avoided taking 50mg when weaning down, as I found the online text quite evident about low doses of quitipine triggering hive like symptom for some users. Double edge sword for dropping the last dose in order to avoid the nightmare of itching as it was for me. I preferred the headaches and found avoiding the low does towards the end of my tapper effective in “reducing” the amount of itching considerably. (This may not be the case for everyone)

    Headaches – I’m still yet to end my second month, since taking my last pill of quitipine. The headaches seem common and something I am learning to deal with. Drinking more water helps. (I don’t like to overload my kidneys – so drink in small amounts and often) Stress – Dealing with stress is quite the task when not so pacified.

    “Dealing with the Stigma of Being Medicated for Mental Instability.” This one can be hard and I’m hoping some of you might be able to identify. I’m speaking more of the behavioral patterns of others with regard to coming off your medication and having to live with others whom are so used to “having” you medicated, that when you struggle – you are greeted with words like -> “Time to go back on your meds again.” This aspect of coming off medication can sure be disheartening. I think for many people, such attitudes are yet another nail in the coffin – so to speak.

    I do my best to simply encourage myself. The first thought that comes to my mind when hearing comments like that is “like no way in hell am I going back on those damn pills gain!!!” I’d rather embrace the anxiety and deal with that as best I can as opposed to the alternative of screwing up my body’s chemical process long term. Like take antacids, use moisturizers, and whatever else I can to assist with the side effects of anxiety whatever they may be, instead of taking meds that numb my brain and give me twenty more Sid effects that will lead me to actually stepping off a chair.

    Forgive the macabre nature of that last sentence. I’m all for living – which is why I had to come off quitipine. Fatigue is definitely something I am continuing to battle. Have tried the doctor and all my bloods seem fine. It’s like some kind of mystery illness that has me wondering whether I have lime disease or not – or something that is not so easily picked up. I’m even wondering if the simply act of sleeping next to my wife as she deals with her own depression and illness of MS is having some kind of residual affect.

    Hard to know – so many factors actually … Age is getting up on me. Pushing 46 and whilst no doubt considered quite young – trying to live in a world that’s seemingly set to be young has me forgetting about the limitations of being human, or what drives me to feel like I do – somewhat fully depleted. Sigh – Anyways – I think given my background in clinical depression and anxiety … I’ve pretty much worn out my tread an in great need of an overhaul with much more insights yet to come.


    TIME – Being real about the damage done to my brain. Not just the past abuse, but also the long term effect of having been on the meds – all of them. – I need to set myself up with a time period of two years off, before I can make any real judgments to how messed up I may be. So I’m giving the process of resetting my brain the time it needs. No expectation on how I should be by this of that date.

    FOOD – Have now reduced the amount of food I eat. It’s an art form that requires its own research. I’m basically eating small meals that are wholesome. Due to the extent of my weight, current fatigue issues and all else coming off and my brain adjusting – Food is by far that most important way to address my health. I’m glad I can see this now, as otherwise I’d easily have a heart attack with the way things currently be.

    OUTDOOR EXSPOSURE: This one in hard, although I do have a back yard. I seem to be very light sensitive and also UV sensitive as well. Yet more imbalance attributed to the meds. None the less – My body – especially my brain … seems to thank me if I am able to give the right mix of sunlight as it be. There is also the fresh air (if you lucky to have any … lol macabre again, but also funny) … I live by the ocean so have no excuse not to get any. It goes without saying, learning to deal with anxiety is quite the lesson with the outdoors … but I pretty much just keep to myself and accept that better than others. I think most time; it’s more about learning to accept others than myself. Hehe.

    I’m definitely looking to do another video update and will link that when done. I am aiming to make that a hopeful outing with good things to share. I guess in all of this – there is much to expect in the way of hardships coming of whatever mood stabilizing meds as dealing with life itself is generally hard enough. I certainly wish everyone the very best in learning to deal with life as best they can and most of all with at least some form of peace. As unfortunate as it may be, I don’t think peace comes without at least some form of stress. So it is that I now get up off my but and go make push myself as little (and a touch more – just a touch) as need be.

  • Bob November 29, 2014, 10:33 pm

    I went from taking 1200 mg, going to sleep at night and then back to sleep to 300 mg. Yes, I went through 2 terrible weeks and thought I was OK. Then after 4 weeks became confused. That was followed with a seizure. Lost my freaking license. Bad drug, sorry I was ever on it.

  • Herbie November 27, 2014, 5:11 pm

    Here’s another issue I’m having that may or may not be related. Above article lists Heart Palpitations as possible withdrawal effect. I’ve got some heart issues at the moment. Nothing I’m too worried about, right now. I mentioned I’m in college classes. Emergency Medical Technician. Been in for as long as I’ve been tapering off Seroquel. In the class, I’ve been dinking around w listening to my heart beat. Speed varies a lot. You can usually tell multiple rate changes w/in any 15 second measuring window. I never noticed that before, but then again, I never paid attention.

    In and of itself, not a big deal. I noticed the same thing on another student, mentioned it, and the teacher said it’s not an issue as long as a person doesn’t feel anxious. The other student didn’t feel anxious. While I do, I think the heart rate is an effect of the issue we are discussing here, not a cause of anxiety. The heart rate would be a brother to anxiety, not a father. But this is a little more worrisome. Yesterday I was moving my stethoscope from one place to another, paused to listen to my heart. Got a random, intermittent, double ventricular contraction.

    Lub, dub.. Lub, dup.. Lub dupdup.. I listened for a while to make sure I didn’t imagine it, and I heard it multiple times. Still assumed I was imagining it. Didn’t notice any rate variations though. Then, of course, last night, I read this page. Breezed past heart issues w/o notice. But this morning, I remembered. Went to grab stethoscope and have another listen. Didn’t hear any double ventricular beats, but did hear a constant variation of rate, including speed/power of individual contractions, and spacing between pairs.

    I went online to check a video we saw in class on Cardiac DisRhythmias, but didn’t notice anything that directly related to the double beat, unless maybe it was a “Sinus Rhythm w Intermittent Unifocular Premature Ventricular Contraction.” But I remember mine more as an added minor double secondary contraction. I’m very active. If mood allows I’m in the gym 2-3 times a week, ride my bicycle to get there, and a 40 minute each way ride to church on Sundays.

    I can recall a few times of lightheadedness in the gym a month or more ago, but overall I feel about normal, physical energy wise. I go to the hospital today for clinical rotations, if I run into a Cardiologist I’ll talk to them. But an update to last night’s post. After reading the page, recent events in my life made sense. I was relaxed and happy. These crazy mood swings are indeed a result of a temporary external force, and not just a forgotten aspect of normal life! I returned to bed, and fell asleep fast, sleeping most of the way thru till my alarm rang. Things will get better. In time, things will get better.

  • Herbie November 27, 2014, 9:28 am

    I’m so glad I found this page! Incredibly reassuring; that all this weirdness is normal! I’ve been on Seroquel for 8-10 years. Initially for a psychotic reaction to Ritalin. Might have been up to 800mg of Seroquel, I know I was on 500mg for a long time. Maybe down to 150 for about the past year. But I got tired of being tired all the time. I decided to stop, dropped by 50mg every three weeks. Got down to 50mg, stayed on that for about a month, quit. Couldn’t sleep. Cut 50mgs up into halves for two weeks, then halved them again but took larger of each half and halved them.

    That for about three weeks, quit. Couldn’t sleep, and I mean for about five days straight. I remember wondering where the headaches were coming from. And itching, oh the itching! But I didn’t know where it was coming from, thought maybe a reaction to new tea I started drinking. Some nausea, but again I didn’t know what to attribute it to. Doc gave me some 25mgs, I took them for a few weeks, then did the 40/30/30 cut again. I’m taking college classes. Started fearing the other students. I’m scared in the gym, I wonder what people in the other cars going by think of me. The suicidal thoughts are awful!

    Thank God I have a family and believe in a spiritual destiny with Him, or I’d have done myself in! Five days ago I stopped the tiny little sections of the 25mg. Fine for a few days. “Great! That was the way to do it! I’m fine now!” Two days ago I started itching again, today it’s back in earnest. Could hardly sleep last night, can’t sleep at all tonight. So this stuff creeps up on you, huh? Crazy. I’m definitely staying off it. Pharmakia, or spelled some such, is the Greek word for witchcraft, and you can see what word we turn it into once it’s English.

    Chemically caused depression, once I know where it comes from, I’ve been able to handle it much better in the past. Now that I know that these weird withdrawals are from stopped Seroquel, I’ll be much more able to deal. I’ve got a month? Maybe three of them? I sure hope it’s only bad for a month, and then gradually goes away. Maybe up to a year? Well, beats a lifetime of foggy headed stupor.

    • Declan Corr December 8, 2014, 11:58 am

      Damn straight bud! Power on through! I’ve done 6 weeks now and the symptoms are letting up, still kinda hard but it does get better =]

  • Kathy November 27, 2014, 6:53 am

    My doctor, psychiatrist, and pharmacist ALL say NOT TO QUIT SEROQUEL COLD TURKEY. It is too much of a shock to your body unless you were on 50mg or less. The same goes for when dropping the seroquel and weening off of it slowly, dont do it too fast. The max I was on was 200mg, slow release and I have to drop it by 50mg as thats as slow as I can do it. I was on seroquel for just barely over 2 years and decided to come off of it because I’m starting to get a lot of the bad side effects like chest pain and muscle spasms/twitching. So please, if your doctor tries to tell you that you can drop it cold turkey or drop you down in dose too fast, DONT DO IT.

  • Melissa Rencken November 25, 2014, 10:23 am

    Hi Everyone. I am also glad I came across this. I have been a Seroquel, Velanfaxine and Epitec since May after a nervous breakdown. I have been taking ivedal for sleep. So 2 weeks ago I ran out of sleeping tablets so went off them cold turkey which I was fine with but then I ran out of Seroquel. (Didn’t have cash to get my script). So I have been off it for a week now. Last week I thought I picked up a bug with vomiting froth like stuff and gastric stomach. Since Saturday I have been itching and couldn’t understand why.

    It just dawned on me that it may be withdrawals so fortunately found this site and I think that’s whats happening to me. Also feeling headachy and cant concentrate (almost a bored feeling). So what does everyone reckon. Should I go back on a taper off or just carry on like I have been? I feel OK but I don’t want to have another breakdown. Hopefully I will also lose a bit of weight in the process as well. I don’t want to take any drugs anymore. I’m sick of it. I wish everyone the best of health.

  • Julia November 23, 2014, 7:22 am

    I’m on day two of my cold turkey quit of 300mg a seroquel and it’s a living and sleeping nightmare. I was taking it for my extreme anxiety and major depression but I just couldn’t stand it anymore. Now I wish that I had weaned off of it. The shaking, the night sweats, the vomiting, the uncontrollable muscle movements, the loss of appetite, the agitation, it’s almost too much it’s really awful. I wish my doctor had never put me on this drug in the first place.

  • Casey November 22, 2014, 3:02 am

    I originally got put on it for Borderline Personality Disorder and Insomnia, but was misdiagnosed and have chronic anxiety and PTSD. They put me on it 8 years ago. I was on 100-150mg. I quit cold turkey 3 weeks ago. Been taking Benadryl and Ativan for sleep. Had flu-like symptoms and dizziness but it went away… but now? I’m a psychotic mess. I lost my partner, I’m about to lose my job, and I’m going to end up hospitalized if I can’t calm down.

    If I get hospitalized they’ll just put me on something else. The anxiety is awful, I can’t stop crying, and I so desperately want to run away…or worse. Now so many of you are telling me that this could last a year, and I just can’t do it anymore. I refuse to go back on it, but I can’t live like this.
    I’m so alone and so afraid.

    • Dave November 23, 2014, 9:38 pm

      Nearing 6 weeks off the drug now. I seem to be suffering fatigue – have been for a few weeks now. Will Check back at the 12 week mark – If I remember. Perhaps summer is not the best time to be coming off it. :)

  • Declan November 19, 2014, 10:48 am

    Heya folks, coming all the way from Northern Ireland here. I suffered what they’re calling a drug-induced psychosis about 11 months ago, Christmas last year – I have to say it felt more like a spiritual awakening to me, it was beautiful =] unfortunately some of my behavior began to alarm those around me and so I agreed to see the doctors, for my mother’s sake. They put me on 600mg seroquel and 250mg depakote. I had awful fogginess, lethargy, reduced willpower and motivation, slept for 12 hours a night with crazy vivid dreams, movie-script dreams – and all of this I had to suffer in silence, get on with my life as best I could.

    I eventually started to acclimatize to all of this and then after a few months began to reduce my dosage…without medical assistance. You see, the doctors wanted me to do a minimum of 2 years. I said to myself ‘no way, I can’t go on living like this for that long’. Anyway, I cut from 600 to 450, 450 to 300, 300 to 150, a month or two between each time, and actually began to feel great on the last cut, hadn’t felt so happy in a long time, though the same lethargy and awful sleeping remained; so, I made the Final Cut about 3 and a half weeks ago.

    Good lord, I was not prepared for this hardship. I thought 2 weeks at the most and I’d be fine. But no, I’m in hell haha. It’s not so bad though, I’m coping well, considering. I’m a spiritual kind of guy so that’s helping me through the difficult times. Main symptoms for me are messed up sleeping pattern, I wake about 3pm, can’t operate for a few hours, don’t feel like going outside so I’m pretty much alone until I sleep at 7am. I stick that for a few days then decide to try and reset the pattern which never works lol.

    Ehh, nausea, tiredness, sore eyes, headaches, some depression, appetite’s affected slightly. But look, all that said, I’m coping grand. I’m sitting in a packed library computer room as I type this, a little freaked out, I should be asleep but I had to get out. All I can say is good luck to anybody coming off it. Be strong and persevere. I know I’m not out of the woods yet, or anywhere near it probably, but it’s helped to read this information and all of your comments. Just some good old-fashioned willpower and strength from your higher power, whatever you wanna call it, can get you through this =] Will check back in after a couple of weeks and let you know how things have improved.

  • Shaune November 18, 2014, 1:11 pm

    I was diagnosed with Bipolar 2 a while back… which, in hindsight, I find was a misdiagnoses. I was prescribed Cymbalta 60mg, Lamotrigine 200mg and Seroquel 150mg daily. After the first few weeks I experienced extreme side effects and because all of the medication was started at the same time, they couldn’t pinpoint which was causing the side effects. Blood pressure was 165/109 as a baseline while extreme fluctuations on my pulse ranging from 80 to 140+.

    I decided to quit all my medication cold turkey, and to be blunt, IT’S BEEN HELL! Unrelenting nausea (no vomiting), headaches, severe insomnia. I can’t believe that doctors (psychiatrists) so easily prescribe medication with such horrendous side effects and withdrawal symptoms that will bring you to your knees. My deepest sympathies for anyone and everyone that’s going through to same hell as I am.

  • Sylveser November 18, 2014, 8:57 am

    I’ve been taking quetiapine for roughly 5-7 yrs with another drug the doctor said it went well together. I’ve gotten myself off that other drug completely (Tapered off) and it wasn’t easy, took 5 months. Now it’s time for quetiapine. I tapered it from 100mg to 25mg in the past year without much problems other than not sleeping as long. I’ve been taking half the 25mg (12.5) for about 2 months and just starting to cut in quarters (6.25) now. The doctor said that if I was taking 12.5 a day, there isn’t much use to taper any more and just skip a day instead.

    But contrary to some reports I’ve read, this drug helps you sleep and have been relying on it for sleep for years. It was my decision to get off the drug as the doctor seems to want me to stay on it at the same dose she put me on even though I’m feeling fine. I’ve read that it isn’t recommended for long periods unless in severe cases, which I was given for anxiety, not schizophrenia or bipolar disorder.

    Since I’ve gotten off that second drug (can’t recall name, but it’s a bad one too), I’ve started to exercise again. I used to run alot before I started getting anxiety. This anxiety was just a phase in a life changing experience and needed something to cope till it subsided, but kept taking the drugs while waiting for the doctor to say it’s time to come off them, but that wasn’t going to happen.

    I feel I’ve been cheated 7 yrs of my life. I haven’t been working and living at home during this time. While taking these drugs, I’ve felt in a cloudy state without any motivation or drive to get out there. Given proper treatment, I probably would have been ok after a year. To sum up, tapering off was better than cold turkey for me, the withdrawal symptoms were too severe.

  • Erica November 18, 2014, 8:03 am

    Quick comment. I have only been on seroquel for a little over a month and low dosage. Quit cold turkey as I have seen no benefit and put on 10 lbs. all the bad stuff is happening to me. If a drug does that to a person taking it for a short time… Only thing to say BAD DRUG.

    • Deb May 3, 2015, 6:01 pm

      I totally relate to what you have said. I am on my second day cold turkey from just 25mg taking approx 3 months and I have been violently sick both days, major migraine headache, and generally feel weak and ill. Thought it was a bug but after reading these posts I assume it’s withdrawal, thought I would be OK on such a small amount.

  • jon holbrook November 17, 2014, 3:56 pm

    I quit seroquel 600mg/day by cutting back from 600 to 300 to 105 to nothing. I am experiencing heavy withdrawal symptoms such as sweating, sleeplessness, upset stomach, and headaches. I do not recommend a fast taper like I did. Trust me it’s very unpleasant.

  • David November 11, 2014, 8:53 pm

    Hi guys, Nice to see others sharing. Unfortunately we live in a world that sells drugs to the wider community. Words like Reliance and Trap comes to mind when thinking of prescriptions based drugs. ANYWAYS – it almost one month now! I am walking twice a day and now my wife comes along. :) We are going to both start eating healthier – although I am now contracted to giving a massage once a day. LOL. Also now lifting some light dumbbells in my house and actually feeling much better around my waist. My core has become so slack and greatly has affected how lethargic I feel. I can only attribute my ability to even try – because I have weaned myself and stopped that horrific drug. I still find it hard to deal with reality outside my home – but I am getting there. I am learning to deal with that as much as I am attempting to regain my strength and mind. Look forward to reading more as people take up the challenge of coming of this terrible drug. Take care -Dave.

  • Jacqueline November 10, 2014, 9:31 pm

    I took 100mg Seroquel for 10 years for Depression. I ceased it on my 5th attempt. The first 4 times the effects were intolerable. The last time I took 2 years to cease the drug. At a dose of 25mg, I started having symptoms of tardive dystonia and gastroparesis. I was hospitalised with dystonic storms on cessation of the poison. I am utterly disabled and have gone from a high functioning Emergency Nurse to begin unable to live alone or work. I have lost 7kg in weight and the medical profession has little to offer. I believe this drug should be taken off the market except for psychosis unable to be treated by anything else. :) Peace and love to anyone who is suffering.

    • GLOOM November 11, 2014, 12:04 am

      Very sorry to hear that you were put on an antipsychotic for depression. The general public has become confused (including doctors) thinking that it is acceptable (and safe) to treat patients with AP drugs for depression. I’m in total agreement with your sentiments that APs should be reserved for psychosis. Hope you are doing better now.

    • Zel August 7, 2016, 1:57 am

      My heart goes out to you. I too was a high functioning professional and psych drugs put me on disability. Love to you. Zel

  • Rae November 10, 2014, 6:41 pm

    I’ve been on Seroquel for almost two years now, and for most of that time I’ve taken 50mg. I take it for insomnia. Since I’ve been on it, I’ve run out twice —once last November when I was off for thanksgiving break and once this past summer — and haven’t been able to get my prescription refilled until the next day. I am still alarmed by what’s happened when I’m without it. I’ve always had issues sleeping, even as a baby; it can take hours to fall asleep and once I do I wake up constantly, sometimes every ten minutes.

    On Seroquel, I can usually sleep well, waking up only once or twice a night (I also take Adderall for ADD on weekdays and my Seroquel dosage isn’t enough to guarantee a full night when combined with Adderall; I sleep all night on the weekends). When I ran out, oddly enough, both times, I had not been on Adderall for a week or so, but I could not sleep for moment for 36 hours. I don’t mean I had a lot of trouble sleeping — I couldn’t fall asleep, period.

    Around the 36-hour mark, my body gave up and I passed out for about twenty minutes (I say “gave up” because my heart was racing constantly, I was sweaty and anxious and shaking, my breathing was slightly shallow; I felt like I was going to collapse and/or die). When I came to again, I was back to being awake and absolutely wired until I got the next dose. Is this normal? Will I be permanently dependent upon it?

    I can’t foresee weening off of it if I cannot sleep for a moment without it. I’m 17, but I’ve been seeing a psychiatrist for three years now and am very informed about my medication. I’m worried nonetheless. I don’t know if this makes a difference, but I take 20 to 30mg of Adderall and 200mg of Lamictal (for major depression). Can anyone offer advice or insight?

  • David November 8, 2014, 3:28 am

    24 DAYS OFF – No added medications to buff the process. I’m experiencing Headaches and Fatigue. I am however sleeping OK. I also need to start watching my diet more and only have just now started walking. Other factors include not getting enough fresh air into my house.

  • vanessa November 6, 2014, 6:38 am

    I’m currently 8 months pregnant and have been on seroquel for about 9 months. When I found out I was having a child I wanted to stop taking it but was advised not to because of the withdrawals my body would face and the harm it could put on my unborn child. I didn’t take it last night and was really nauseous all day and for the last hour have been severely itchy.

    My OBGYN told me to take it tonight so she can consult with another doctor about what to do. If you are a woman who wants to have children one day DO NOT start this medication. My newborn is going to have to face these disgusting withdrawals. She’ll have to spend WEEKS in the NICU once I give birth to her. This medication does more harm then good. I haven’t been on it for long but it’s tormenting me.

  • Jerry November 2, 2014, 10:39 am

    Hai all. More then a month ago I quit the Seroquel. Its all way better now. No more insomnia, exhaustion and all that.

    What worked for me:

    -Taper off from (in my case) 100 to 25 mg. Tapering off is in my case not the worst, its quitting totally.
    -Mirtazepine (remeron) helped me coping with the withdrawal effects. It did wonders for me, even a small dose helped me to get my sleep back and helped me to function during the day. It did nothing for me when I tried to quit at a 100 mg level.

    After three weeks of insomnia, I took remeron instead of sleeping pills and muscle relaxants. That made the list of symptoms even longer. It seriously helped me to overcome all the nasty withdrawal effects and it is a non addictive, easy to quit drug when you use it for a short term. So be patient and with a little help it can be even bearable to come off that nasty drug. Hope it helps for someone. Good luck all.

  • Mike October 31, 2014, 6:42 pm

    I have been taking Seroquel for over 15 years. I am starting to show the side effect of Tardive dyskinesia (TD), look it up, it’s really nasty. I am starting to reduce my Seroquel from 100mg.

    • David November 2, 2014, 2:46 am

      I believe ya. 17 Days of the Seroquel Now – I even picked up some WORK! Not that it means I am now Saved. But it goes to show just how complacent the professionals by placing so much emphasis on being long term medicate for the masses when it comes to mental instability – AKA “The By Product. “Take a pill and chill!” We as victims, also become complacent as well. I am still having a little hard time adjusting, but over all – I am still getting psychotherapy and accept using medication for PRN – but no longer interested in poisoning myself long term. I’m starting to live again, and doing things I like to do.

  • Caroline October 29, 2014, 7:44 pm

    I was on 100mg Seroquel and Solian 400mg for eight years. It has been hell for me. I started decreasing my Solian slowly from 400mg to 300mg without side effects, but in June when I went on tapering further I had nausea, vomiting, insomnia, but I still functioned pretty well regardless, I was taking 4 X500mg Gaba Capsules to alleviate the anxiety as well as eating Gaba rice, yoga, acupuncture three times a week. I was tapering my seroquel to 50mg then to 25mgs where I stayed for three months then I started getting what presents itself as atrial fibrillation which stopped when I stopped the seroquel but since I have had breathlessness even at resting, the insomnia persists, I now have fluid retention which is a bugger to deal with at the best of times.

  • David October 26, 2014, 10:50 am

    Ten Days Clean – lol – Fancy saying it like that. My head has been spinning, but seems to be winning. Those other two days were like hell. So so tired and could not sleep despite trying. I’m still feeling a little run down, but nothing near as bad as before. I can feel my head working hard to keep a balance and now understand how it is that I can tire so quick when using my brain. I laugh to think on that.

    Still under the two week mark though – I am waiting for day 14 or there about… hmmm… possibly more, because I like to start with the week. I am referring to an exercise routine to which I know I will hit hard. I know not of any other way… I now laugh again to think of myself run into the ground. I’m just going to use some light dumbbells and my elliptical. Goal has to be weight loss, but not straight away. So far so good – I fear the itching might come when I exercise, but I reamin hopeful… we shall see. Here’s to Day 10 :)

  • David October 24, 2014, 7:19 am

    Day 8 – Night 9: I am struggling with fatigue – hard to sleep at night… Hopefully this will change over the next few days. I feel exhausted although doing not much at all.

  • David October 21, 2014, 10:44 am

    Night Number SIX, since I have stopped taking any seroquel as all. Was on for 2 Years. 50mg to 100mg to 150XR. – Tapered Off for a few weeks down to 75mg then stopped Six nights Ago.

    Day five and now night six:

    Still have runny nose with tingles and warm sensations that come in waves over my body. Also very fatigued. I am hungry (as was the case on the meds) but now I feel sick when I eat. Today I had to lay down due to many hours of a sick stomach combined with the fatigue. Generally I fight feeling tired, but today I just knew I had to listen to my body or otherwise faint.

    I am a little worried where this may lead, but still optimistic about my plight. I’ve come too far now to simply go back. The itching seems way more bearable than last time I tried to give up. I was exercising at that time. This time I am avoiding the exercise early on given my tapering off is as much a case leaning into cold turkey. I hope the 2 weeks weaning off with 75mg was enough to help – but somehow think not enough to avoid many of the cold turkey symptoms.

    I must avoid over eating or at least choose easily digestible foods. I’m getting around 5 hours continuous sleep with a lot of tossing and turning in the beginning and then when I wake up. My plan for good sleep is not a return to the meds – During this phase in coming off … it’s to be expected. How long this goes on will be the focus of my concern … not the symptoms unless I’m straining my heart and setting up for a stroke. Those things I am on alert for.

    I am going to take three Valerian tonight. My tummy is quite ill and I think it will help to take the edge off with less tossing and turning. Valerian is just a herb which for me has helped me sleep in the past.

    Until next report :)

  • David October 19, 2014, 6:31 am

    Hi Rachael, sorry to hear about the long haul there. I can relate very much to the side effects you have mentioned regarding being on the medication. I like both what you said about the emotionless state and also the longing for your mania. Made me smile. The drugs take away our passion. I have been making gains with mindfulness. I went for a walk yesterday. I wandered off track like I normally do into the woods away from the people using the track. I made a video both to share my experience and also to push myself in a way that’s positive without overdoing things whilst coming off the meds.

    If the Admin of this blog does not mind, I’ll share the link:

    David & Mindfulness:

    Please forgive my stuttering and slurred speech. Whilst getting flustered with my thoughts in public situations is a common thing for me, I feel the meds have not made that any better and then coming off on day 3, I guess I’m a little stressed as well. But I choose to remain as positive as I can. Don’t get me wrong – I do not subscribe to the “Happiness Trap” but I also acknowledge my negative thoughts and very long state of depression over the decades have debilitated as much as the side effects of my medications. Mindfulness helps me to create much needed space in my otherwise chaotic head.

    Anyways – I don’t really know … I’m on Day four now – still sneezing and finding it hard to sleep. I am thankful that my skin is not burning this time around. I expect and accept the discomfort that is yet to come – I welcome it as part of my plan to reclaim my health. Like when I gave up smoking 8 years ago … I count each day from this point on as a day towards my well being.

    This is also a link to my Flikr account – it somthing that shows what mindfulness does for me, despite my inability to fit well in society. But that’s OK – like it’s OK to be alone – I just have to learn to accept it and not worry about what others think. That’s my advice – for myself today.

    https://www.flickr.com/photos/[email protected]/
    Best wishes – Keep strong.

  • Rachel October 18, 2014, 9:18 am

    I quit my dose of 400mg a day 6 months ago. Firstly trying cold turkey & then took 6 weeks to taper off. I hated being on the stuff for 2.5 years. Gained weight & became emotionless. The withdrawals were shocking & like nothing I’ve ever experienced in my life. I had 3 months of physical withdrawals. Vomiting, shaking, insomnia, sweats etc. followed by anger, psychosis, unconquerable depression & crying.

    Now, 6 months on, I am still in a bad way. My body & mind has completely broken down. I find it impossible to function & achieve basic tasks. I can’t even dress most days & I’m constantly exhausted. My sleep pattern is messed up. I wake between 1&4am daily. I am very sensitive to light & noise. It feels as though I will never recover. This is the worst breakdown I’ve had to date.

    I will never touch another antipsychotic drug again as I’ve lost nearly 2 years of my life from seroquel. I have lost all interest in life & if not for my 2 sons, I would be suicidal. I am bipolar 1 & the only thing that keeps me going is the thought that this will pass eventually. I long for my mania to return & the huge lust for life that comes along with it. I believe this drug to be incredibly dangerous & unfit for man or beast!

  • David October 17, 2014, 10:08 am

    2nd night without my meds, dropped off from 75mg – I could not sleep, but that was a blessing in disguise as the itch can get real bad. I am pleased to say that although I have been up for 20 hours, I am thus far able to handle the itch. I am drinking lots or fluids, mostly clear and or herbal tea.

    I can feel my immune system on the edge with flu like systems about to kick in, therefore no exercise just yet. I will make sure to go for a walk tomorrow and get a little sun – maybe do some yard work if no hot flushes like I had come and go today. With regard to the no sleeping – I found it best to get up and do some writing. Staying in bed and fighting it seemed counter productive to me.

    Here’s hoping to some more sleep – if it happens again, I guess I’d do the same thing, however this time I will sleep some the next day. I note the hints in this blog. I’m pretty much following them. Best of luck guys – It’s not easy … but there have to be other ways. :)

    • Suzy October 19, 2014, 11:29 am

      How are you going now David? I have just stopped taking seroquel too – four nights ago for me. The itching has been unbelievable – I had been thinking that I was having a severe allergic reaction to something but now realise that the itching is happening because I stopped taking seroquel. I have been finding it really hard to leave the couch too, and have felt like I have a cold. I haven’t slept properly for four nights. Trying hard not to turn back now though.

      • Kim June 10, 2016, 8:42 am

        Hi David, two weeks ago I was rushed to ER with drug induced hepatitis. The problem raised levels of Seroquel, thus was taken of ALL Seroquel. Cold turkey (1/06/2016). I have found great success for insomnia is Melatonin. I take two at about 8/9 pm and find that I sleep about 7/8 hours a night.

        After reading this site I now have an understanding of why I am so itchy and am sneezing so often. I have yet to experience the worst of the side effects listed above, but I have enlisted the help of friends and family to help monitor me for relapses. I am trying to keep a diary of my experience. I really believe that faith in God and prayer help. Please be well.

  • David October 16, 2014, 10:32 am

    NIGHT ONE – off Seroquel/Quetiapine.

    I hope its OK, if I can join on in here – recording my own efforts coming of this drug? I’ve been on it off and on over the last two years – mostly on because the first time I tried to come off it, I suffered extreme itching like many others. I can only see this drug as a trap the longer I stay in it. I am now obese and more depressed with no energy at all. I started on a 50mg dose and went to 150 – the XR was no good for me – too tired for too long.

    I’m now down to 75mgs over the last week – tonight being my first night complete off. I wont take the 50mg – because low doeses also set up the itch for me. High doses are actually taken by many simply for it’s anit-histamine properties, but again – in low doses it triggers the itching. The Sad fact is – I know I’m also going to go through hell with itching coming off – Burning skin and all. Not to mention most of the other things already mentioned. If no objection – I’ll continue my records in here?

    I’m thinking about taking phenergan (another antihistamine) BUT – I will have to wait and see. I’m going to go walking and have an elliptical that I can use (with no resistance) – see how I go sweating … but will watch the flu like symptoms – I may very well not do much at all. I’ll have to wait and see. For me – the itching is like hell – it’s on par with having Scabies – a human form of dog mange. To make things worse, I live on the coast with mosquitoes and midges!

    LOL – I’m just going to have to meditate all this through and try to laugh at the insanity of it all. I’d prepared to suffer for a few months if it means I can reset my body’s antihistamine levels as too my metabolism and much much more. Instead of forcing people to take these damn meds, they should enforce compulsory group therapy and or mindfulness. :)

    Best of luck to you all.

  • Virginia October 14, 2014, 10:11 pm

    I have been on 200mg of Seroquel for 4 months and last month started to taper off. It has been about 4 weeks and am down to 25mg. Every day seems to get worse instead of better. It is horrible. I can’t believe they would give you a drug this bad. I am also taking Zoloft hoping that it isn’t causing some issues also. They say it’s going to get better but when it’s awful that’s all I can say. It’s a bad drug. Any helpful and encouraging comments would be appreciated.

    • David October 17, 2014, 10:30 am

      Hello Virginia, sorry to hear about your struggles. I was on Zoloft before the seroquel and at some stage was taking both. I gave up the Zoloft at about 12 months. It helped at first, but like the quitpine/seroquel, it reached a stage that where I had begun. Weight gain and lost of will. I don’t believe these meds should be used full time – they have their uses to be fair and it would seem some people can handle them longer than others.

      I still suffer extreme anxiety, social phobia and depression. Suicide attempt only weeks ago. Having said that though, I checked myself in at the local hospital and now getting help/phyco therapy and all that. Have a support person. I’m looking to first regain my health with this plan to come off the meds. Again, I don’t believe even the doctors expect some people to rely solely on meds. I will use the PRN/if things go bad – but not with the same reliance that can unbalance things as time goes on.

      Hard to explain and sorry I can’t be concise. I do lots of things – or used to before I hooked into all the prescriptions given to me. You get some doctors that listen and others who seem hard of hearing. I have had to change a few – but now think I have one I can work with. Mind you though – this action I now take is my own plan and not one I am wasting with the doctor I see. I’m only on welfare… so is best not to drain him with stuff I know I can do myself. (He is more pro-meds – but I am done for now changing docs like my jocks).

      They have seen me up and down, but I always say sorry and try and be friends. They actually like that because like professionals that grow wearing – so do many patients. I just want to get along as best I can. Generally speaking though – I don’t do people very well. I actually can’t hold down a job and on a pension for my instability – which requires me to have some kind of plan based on stability. It’s just a damn shame that they gauge such a thing based on meds! That really makes me sad, because like I said – they can be good for a while, but things like Psychotherapy, or just plain socializing can do so much more.

      Being part of some kind of group that accepts people for who they are. I might be getting into some kind of writing course yet on top of other things – but I pull up here and not bore you all with such things. Take heart – there is a huge amount of self doubt and negativity on the internet – I find it’s not so bad to commiserate, however there also comes a time where one has to find hope. There;s just too much pain in the world as it is – as you may or may not know, there comes a time where if one is still breathing, then it’s best to make the most of what little is left. Turning to nature is good for such things.

      Righto – best of luck – we all have the power within … some just need a gentle touch and a little reassurance that not everyone in the human race is all trying to be someone they are not. It’s OK to be right where you are. Peace to you and yours – if no others, then all the more for crossing paths.

  • Jerry October 13, 2014, 5:50 pm

    Its been two weeks now since I am off the seroquel. The main problem is overall exhaustion during the day and severe insomnia that even a high dose sleeping med cant beat. My body is to tense, especially my legs and mind. I try clomazepam once in a while, it seems to work a bit but it comes with…surprise surprise…nasty side effects.

    I am hoping someone can share me their experience, especially considering the insomnia. How do you cope with that..? Meds? Herbal/ natural stuff, mindfulness, yoga? And how long did it take to beat those withdrawal symptoms? I need someone to say it’s temporary because I am getting more and more frustrated and desperate. Reading all those posts above tells me its a challenge for a lot of people. I think you can really be proud of yourself if you finally are able to get clean because it takes a lot of awful setbacks to overcome.

  • Janet October 12, 2014, 5:34 pm

    I took seroquel for one year and my doctor decided it was time to come off because if ling term effects. He tapered me off and it took two months. No problems. He retired and the doctor that took over insisted I was given bad advice and must be put back on seroquel xr 200 mg. I trusted her and two years later I have decided I am tired if feeling like a zombie.

    I told her I wanted to taper off. She said that was not possible. If I wanted to quit I just needed to stop taking the drug. Well I did and the withdrawals were so horrible I was back in her office begging to be put back on it. Since that day I have been trying to get off. Every time the withdrawals are too much. Attempting it again and on day two and feeling nauseous. Sure I will fold again, wish I had never started.

  • Natalie October 11, 2014, 8:17 pm

    Hi, I have been on 300mg of Quetiapine for 2yrs after being diagnosed with bpd, my Doctor has suddenly taken me off it cold turkey. I feel so awful: nausea, bad stomach, insomnia, vivid dreams if I do get sleep, headaches but the worst is the constant nausea, I can’t eat or even think about food. How long will this last? It’s been 2 weeks and I’ve never felt so sick in my life although the doctor says I shouldn’t be feeling too bad. I’ve tried explaining that I do so thank you to everyone that has posted on here. At least I know it’s not all in my head, I just hope this nightmare will soon end, good luck to you all.

  • Jim Okeeffe October 9, 2014, 1:41 am

    I am a 63 year old male. I have been taking Seroquel 200mg + for over 10 years. A couple of weeks ago I decided I was done with this med. I was very ill for 6 days and went back on it. Severe withdrawal. I have been through a narcotic withdrawal and got off that but I am troubled wondering about getting off Seroquel. I can’t believe information on the severity of symptoms quitting this drug were never presented.

    I am angry. And the extended time needed to feel “normal” again. I’m reading at least a few months to a year or more. This is outrageous. I have looked into inpatient medical withdrawal programs using a protocol particular to Seroquel but the thing is the time needed. Narcotic withdrawal can be accomplished fairly quick but this drugs negative effect is long lasting. I’m not sure what to do.

    I guess the gradual reduction is all that realistically can be done. I will probably start some other drug as a comfort drug during the taper period. I’m thinking of a benzo. I have quit long term benzo also so a year or so controlled use looks better to me than living with the prolonged effects of getting off Seroquel.

  • Caroline Constantinou October 8, 2014, 9:55 am

    I have been on Solian 400mg per day and Seroquel 100mg daily for eight years. I decided to do a detox as I felt terrible, first I detoxed by stopping coffee, dairy, meats then the medications. I was tapering down to 25mg Seroquel for a couple of months with support of acupuncturists three times weekly to help with symptoms. My body responded positively my sinuses disappeared but now the other symptoms now I deal with are insomnia and tiredness upon exertion from the dreaded seroquel!!!!

  • Tyler Sellers October 8, 2014, 6:14 am

    I’ve been on this drug for 5 years at 400 mg daily because of my mental illness. The tramatic experience of losing my mother at age 7 has always been the root of this. Trying to call home through the 911 operator turned out to be a catastrophic decision as I was essentially arrested and forced into rehab where they would commit me to this medicine. I will NEVER get off this drug!!! I just don’t see it as a realistic possibility.

    My shrink writes up these ridiculous suggestions such as eating healthy as well as exercise when I express my concern of the ugly stretch marks that have covered my stomach. The weight I have put on is excessive. Long, long ago I used to be slim like about 175 lbs. These days I’m at least 230 and its all belly. I look like Peter Griffin. When I tell this doctor I don’t like it she recommends adding more medicine! I don’t know what it was nor do I care.

    At first this actually seemed to make my life better but by now it has really taken its toll on me. This drug is equal to a never ending stint as a prisoner in a insane asylum. It stops me from being me. Without it I definitely would’ve found a way home a good while ago. Instead my brain is altered and balance the way the pharmaceutical companies feel it should be. I’m treated poorly at work and don’t get the respect I know I deserve anywhere else.

    I’m supposed to see this doctor next week and don’t know how I should conduct myself in the interview because I just want out. I can only hope one day I am roaming the streets and get met by a gigantic storm of bullets. That’s absolutely the only way this can end. For those of you who say you quit cold turkey I don’t believe you. For those who want to forget it!

  • Marie October 5, 2014, 5:05 pm

    I was on 200mg at night and 100mg in the morning. Quit taking it about 4 days ago. feel like absolute hell. Sleep is almost non existent (until I’m so tired I pass out). Luckily I took vacation from work so I have some time to work this all out. Day 3 was the worst so far I was sick to my stomach and I was hurting soo bad I actually had to call off work. This is not going to be a fun trip.

  • Krystyna October 4, 2014, 9:21 pm

    I’ve been taking the horrible drug called quetiapine. I’ve been taking this for many years; my diagnosis is emotionally unstable personality disorder. I started of taking 400mg and thanks to a recent hospitalization they put me on 600mg as well as Venlafaxine I have recently decided to come off this drug and it makes me feel really bad burning chest and back.

    Tiredness all the time I was literally sleeping twenty 4/7 agitation in my legs can’t concentrate so I came of it cold turkey now I suffer from insomnia migraines 24/7 vomiting nausea hot and cold sweats. I feel like I’m dying and the psychiatrist said I should go back on it, but I’ve had enough of this awful drug so I’m putting up with the withdrawal symptoms. -Krystyna

  • Melissa October 4, 2014, 6:14 am

    I’ve been taking 300 mg of Seroquel for the last 18 months, I just quit taking my Seroquel cold turkey a week ago. I’ve had nausea, eye pain, vomitting, headaches, insomnia, heart rate changes, Concentration problems, fatigue. It’s been a very bad week. And I know it’s going to be hell for quite a while but I WANT to be drug-free really bad enough to go through hell to get there. Will power.

  • Phil October 3, 2014, 7:44 am

    I just tapered by 200mg and the day I stopped taking the med, I can’t sleep and today is day 2. Is anybody having severe (can’t sleep at all) insomnia from Seroquel withdrawal? Thanks.

    • jenn January 16, 2015, 3:57 pm

      Yes!!! Last night was my first night of no seroquel… I didn’t sleep a lick not to mention the shakes and dizziness this morning!! I hope I can get some rest tonight!!

    • Cathy February 10, 2016, 2:27 pm

      YES! I can’t sleep, eat and have nausea with side effects that come with that. I want to feel normal again!

  • Finally free September 29, 2014, 6:49 am

    I just want to write a few lines of hope to the people who are trying to become med free.

    It has taken me over 3 years to completely withdraw from this drug. Reducing 50-100 mg every 3 months.

    I was on the highest dosage with a cocktail of sleepers , anti depressants and diazepam.

    The sleep is truly a killer, the aches, pains, inability to watch television with the lights. Sickly feeling and the sweating ( hung over ) there was times when the withdrawal was worse than the condition.

    However after having a strict diet of protein and veg. No alcohol , coffee, pop fizzy drinks, caffeine , no take outs, fried food, chocolate ( rarely) I have not only got off the drugs but lost 5 stone (70lbs)

    Advice – setup a exercise plan. No matter how rubbish you feel get up and out. Fresh air is the key ( helps with the dizziness and sickly feeling )set goals especially food cook fresh gives you something to occupy your mind.

    Remember why you want to withdraw and keep a diary. I didn’t realize how numb I was emotionally. I now feel human.

    Good luck

  • Jeff September 28, 2014, 11:10 pm

    First of all I want to sincerely thank all of the above posters. Your comments literally saved my life and gave me the kick to hang on. I had no idea about the dangers of Seroquel until I had already quit them cold-turkey. That was the beginning of what was literally the most horrific month of my life. It was a 24/7 panic attack of the highest degree, along with constant nausea, diarrhea, dizziness, days upon end with no sleep, severe suicidal thoughts, waking nightmares, and every single minute was like an hour.

    I pray that anybody even considering taking this hell-bringing drug does some research and finds this page first. The irony is that at my Pmed’s office there were Seroquel magnets ALL over the place so it’s clear that they are getting rewarded for pushing this garbage. It has been 4 weeks now and I am still feeling minor emotional effects but I have survived the worst time of my life. Out of curiosity, I am the most non-litigious person around, but does anybody happen to know if there is a class-action suit against AstraZeneca, and/or if there is a certain type of attorney I need to seek out to initiate something?

    After disrupting our whole family with such terror I would love to see these diabolical pushers have to face up to what they have done to me, and so many others. Again, thank you all for your uplifting words, and convincing me that I would survive. Thank you!!! Jumbled Jeff

  • Bonnie September 28, 2014, 10:40 pm

    23 years old … Been on 600mg for about a year and a half for Bipolar/borderline personality disorder/ ocd and ADHD. Started meds when I was in a crazy place… I was breaking down crying every day, I was starting rows with my best mates telling myself they weren’t there for me and picking out the smallest things just being horrible, I was smashing my house down in fits of anger …. Smashed a 52 inch brand new plasma with a deodorant tin and was out of control…. 4 overdose attempts layer I was diagnosed and started on the meds.

    Always took it at night or I wud be monged during the day. It completely helped me mentally …. But I was pretty much confined to my flat through being dizzy and worried and anxious about leaving. Going shopping would worry me …. And then I brought a horse and started going out every day… We’ll that was 3 months ago and I now manage the whole yard and I have never in my life felt more stable and happy. I actually really get myself now and have the best fella I’ve ever met supporting me so I stopped my meds completely cold turkey. He said when we got together as a joke he wud get me of my meds and I laughed my head of and said no way! Never ….. I need them to b normal*ish.

    When I got the hump with letting people down at the yard … Being a grump to wake up I thought that’s it. I’ve never been happier in my life so now would b the best time to try. Well I’m 4 days in …. Finally managed half a sandwich today. Haven’t had any side effects apart from not being able to sleep a wink…. I lay awake like all night with my eyes closed but get up in the morning like a bouncing bean and manage to do a lot of hard graft and I’m still here wide awake Lol. I haven’t had any other symptoms really …. Maybe a little bit sick at times but I put that down to no food. I’m crossing my fingers that I don’t start getting worse with symptoms like some of you guys. Good luck to all of ya, your posts helped me get an idea of what I could b expecting. I had done no research whatsoever so a bit scared but glad I’ve got the knowledge now :)

  • Jordan September 25, 2014, 12:34 pm

    I’ve been on seroquel since I was 18 I turn 23 next month… I’ve not been able to hold a job longer than a few months and I believe that it is this drug that is causing this. I usually take up to 3oomg fast release a night solely for insomnia issues, but time has flashed before my eyes and it has already been 5 years since I’ve started taking this drug to sleep every night, and honestly do not know if I legitimately have a sleeping disorder anymore or If I ever really did to begin with.

    I feel like my life is passing me by due to this horrific drug. I tapered all the way down to 50mg a night and now this is night 2 of absolutely no Seroquel. Wish me luck, btw it is 5:30 a.m. and I still cant sleep but I’m sure this is a sign of withdrawl… Hopefully. Thank you everyone It really does help knowing you’re not the only person wanting off this drug =)

  • Jerry September 25, 2014, 12:32 am

    I’m very glad to have found a site like this and to read all your experiences…i have quit seroquel yesterday and i’m really worried what is coming to me. Also I found that there was little information about how to cope with withdrawal. You need also a SOCIAL and medical plan to combat the withdrawal. I try to be one of the first.

    After 5 years on 100 mg as a sleeping aid it has lost its magic and turnt on me. Well, its not really magic because its hijacks your emotions but for sleeping it worked brilliantly…for a while and then it kept me awake. If I was lucky i got 4 hrs a night. It was wearing me down and the pressure to perform and function my ordinary life was killing at that time. My goal is to sleep on my own and finally be energetic and to ‘feel’the life as anyone should be.

    The first time I tried to quit at once. From 100 to nil. People dont ever do that at once. Or at least read about so that you can expect what may be coming your way as well. I was chronically awake, in panic because I convinced my self I would never sleep again, anxious, had to ate 5 times a night, and thought this feeling would never stop as well.but it seemed i was getting emotions back…i was really horny again.☺️ I cant believe how this drug messed up my libido. What else can I experience again without the drug?

    Now I am down to 25 and give it my best try again to quit totally. This s supposed to be the hardest part. I gave myself some space in order concentrate totally on my withdrawal. I took a break from work and other appointments to eliminate the stress of feeling obliged to function while feeling like trash.

    Tonight didnt take my 25 mg dose again . I have tension in my legs, fatigued, i have to eat 5 times a night without feeling satisfied etc. during the day i can be extremely aggressive and irritated about stuff i see or read. I have clonazepam to battle the insomnia… I’ll use that to tomorrow…my plan is to watch TV all night just till I eventually fall asleep. I’m not going to wait for something that may even not come, so frustrating.

    I hope this can be helpful to some one. I’ll report tomorrow again

    How do others COMBAT. Withdrawal?
    greets jerry

  • vince September 20, 2014, 11:24 pm

    I have been on seroquel since 1997 when it first came out. I have diabetes because of it. I am trying to taper off and it is awful. I don’t know anyone who has been on it as long as me. I need help as my doctor is a bit of a quack.

    • Shannon Barnes February 6, 2016, 8:24 pm

      I was on 400mg to help me sleep and I tapered off of seroquel until I got to 100mg. Then I just quit cold turkey. I had BAD insomnia for about 3 weeks. I didn’t feel like doing anything. I CAN’T BELIEVE A DOCTOR WOULD GIVE SOMEONE SOMETHING THAT COULD MAKE YOU FEEL SO BAD!!! I can’t walk because I was in a car wreck.

      Now that I don’t take any medicine, I seem to be doing better. If I would have known what this drug could do to you, I would have never taken it! OMG!! The itching was terrible!! When I was taking all the medicine I had headaches all day. Now that I don’t have headaches, I can deal with walking. I think you should get off of seroquel!!

      • HELEN WARMAN October 21, 2016, 2:39 am

        I have been on Seroquel for 8 years. 100mg also 150 XR. I dropped the XR after a couple of months. Lately I have weaned myself off sertraline 200 mg, then weaned off Lamotrogine 200 mg and finally have weaned off seroquel – I went down half a tablet every month till I got to 12.5 mg.

        Stayed on that for 1 week and stopped. All was fine-ish, lack of sleep. but the itching has started to get worse- 3 weeks after stopping. Instead of just a mild irritation it is getting worse. Anyone managed to get through this stage?

  • Brian September 20, 2014, 6:13 pm

    After 6 years of 400mg per day and to much weight gain I came off seroquel and have had terrible itching all over my body it’s terrible has any one else experienced this symptom please let me know?

    • Kara October 30, 2014, 2:21 pm

      Yes I am itching all over, that’s why I found this site because I was trying to figure out why I couldn’t sleep and was sooooo itchy. I have run out of zopiclone and quitiapine as I couldn’t make it to the pharmacy in time to pick up my prescriptions…. I am not intentionally trying to stop but am thinking now that I should. I have been taking only a small dosage of around 100mg most days but am on other meds for Fibromyalgia symptoms which are almost identical to the side effects of quitiapine use that others have described here.

      The weird thing is that I was experiencing these symptoms before I started taking quitiapine. The drug helps me in the short term but what is it doing to me in the long term? right now I am unable to sleep and am itchy all over. Have had really terrible feelings of depression in the past week which I just put down to hormonal changes during menstruation. It Sucks. I hate that some days I can’t face even talking to anyone. Does anyone have any answers to how to deal with this sh#t? Tired and wired. :-(

    • Dave February 17, 2016, 4:24 pm

      Yes and the bad thing is that the itching takes a long time to go away. Benadryl is the only solution. I was put in prison for a year and 3 months in they stopped giving Seroquel to inmates and switched me off of it. The itching never went away for me. It is severe itching too. The day I got out of prison I started my Seroquel again cause I had some at home and the itching stopped 30 min after taking the pill. A lot of people stop and have the itching problem. The only solution for me was to take Benadryl.

  • JJ September 18, 2014, 7:58 pm

    Hello. I just wanted to share my story with you all. In my case, I have two family members who take Seroquel. One is 17 and has been taking it for almost 5 years. Over the past year, the doctor has agreed to lower his dose, aka taper it off. In the past month, my little brother has been diagnosed with low blood pressure, and now he is being tested for thyroid disease. His family doctor had to look up the side FX of seroquel and confirmed that low blood pressure and thyroid issues are indeed potential risks. The sad thing is he was only 12 yrs old when he was 1st given Seroquel during his first major depression. It’s worrisome that such a young person has had this drug in his body during such important years. I am saddened, but hopeful that we are as a family moving in the right direction – to eventually see him be seroquel free. After reading all your stories, I can honestly say tapering off sounds much better than cold turkey.

    I wish you all health & happiness,


  • Andreia September 17, 2014, 11:03 pm

    Hi, i am Portuguese and i am in the seroquel trap too, for almost six months. It was prescribed by my shrink for depression and anxiety. I feel cheated, in a no return train because of this medication… i wish i never put this poison in my body and brain. I’m so scared when i think in starting a Seroquel withdrawal. Weeks ago, i forgot of taking just one pill and i felt like i was in a tiny boat in a storm to hell. I need your help. I want to start but i am to scared…

  • Sarah September 16, 2014, 7:56 pm

    I am coming off quitiepine, I can’t believe all the awful stories I have read about this awful tablet. I can’t believe that any Dr can prescribe this for anything other than serious disorders. I was diagnosed with borderline personality disorder about a year ago, and have been on quitiepine ever since, I have put on an absolutely massive amount of weight, and it’s the weight gain that has pushed me to want to stop, but the side effects I have had since cutting down are horrendous.

    And I’m still cutting down, I’ve been doing it slowly but after reading all the awful side effects it can cause, I feel like I want to stop immediately but then there are horror stories from people that did it cold turkey, so now I’m confused as to what to do for the best, I really want to be off them now, but am worried that I could potentially make myself a lot worse if I do. It’s a nightmare to know what to do for the best. I was on 300mg and have come down to 75mg in about 5 weeks, now I’m on a low dose, is it really going to cause my withdrawal symptoms to worsen if I just stop taking them??

    If anyone can reply to that question I would really appreciate your advice. I want to be off this awful drug as quickly, but as safely as possible. Any comments regarding what I’ve written would be so gratefully received. Also, it’s nice to know that I’m not the only one, it can make you feel so alone in the world, so it is a comfort to know I’m not alone.


    • GLOOM September 17, 2014, 2:11 pm

      Hi Sarah, keep tapering slowly and do your best to put up with what you experience while coming off. I am very surprised you were put on this med for Borderline PD… Antidepressants and anxiolytics are regarded as being much safer long-term options.

      Additionally I’d recommend seeking the help of a therapist who knows DBT (dialectical behavior therapy) as this is an effective non-drug option for Borderline PD. Withdrawal will be different for everyone, so it’s not easy to say whether you will have extreme symptoms or not until you make the full transition. Whatever you decide to do, wish you nothing but the best of luck.

    • Thriver January 3, 2015, 3:27 am

      During the withdrawal of long term over prescribed benzos (lorazopam and clonazapam) I was unable to cope and did a self admit for ten days. During that time I was given seroquel because I was not sleeping. The 300 mg seroquel was a short term solution to a larger problem. Though I am still detoxing from the benzos I was guided to now dose down the seroquel. After reduction in doses by 50 mg every two weeks for about two months the withdrawal symptoms started only after I stopped taking seroquel completely.

      I was put on restoril to aid in sleep one month prior to stopping the seroquel. So it has been about 4 months of all benzos, one month off of seroquel and one week off of the restoril. The withdrawal is pretty awful with all the above described symptoms. However, for me, the episodes on all these drugs were horrible in comparison. I am managing the itching with benadryl every 4 hours and it also helps me sleep when I am tired enough. Yes, I am bed ridden. I am giving myself in total another 4 months to completely stabilize.

      I am offended by the mismanagement of my mental health by a doctor who said my PTSD would always worsen. With the aid of EMDR, CBT and now DBT I now know I can, and am, getting more cognitive clarity. My mood is stable with low doses of lexapro and lamictal for the night terrors. Just giving myself permission to rest, eat right, take a 5 minute walk every few hours, nap. Still have nausea, high level muscle/joint pain, depression, etc. but it will pass.

  • yvette September 10, 2014, 10:34 pm

    hi first of all i would like to comment on how i appreciate the other comments on this site. i have been taking seroquel 10 years. the dosage ranges from 100 milligrams to 300 milligrams. i have had a range of psychiatric problems for most of my life. i am now 53 years old. i have decided to stop taking this medication as my quality of life has been appalling for the last 10 years.

    The worst part has been my total lack of motivation. it is as if my life stopped, it feels like i have done nothing for 10 years. i have been isolated and housebound. I cannot bear being like this any longer, that’s why i have decided to stop taking this drug. one of the scariest things is is that it seems to take away your willpower. i am hoping that the withdrawal process won’t be too severe. if i can find the site again i will keep you posted to how i get on.

    • Thomas January 1, 2016, 9:05 pm

      I’m trying to taper off Seroquel XR and Invega. Both of these drugs have much the same withdrawal effects. I was taking 900MG of seroquel XR for the last four years. For the last six months I have cut the seroquel down to 300MG. I was able to stop the Seroquel for two weeks. Had a hard time with fear, agitation, anger, depression, anxiety and suicidal thoughts. So I went back to the 300mg. Of course I had problems with sleep.

      Now I’m taking 150mg, breaking the 300 in half. Having again the same cognitive side effects. Fear and anxiety are over-powering. Agitation, poor thought process. These mental problems are huge. It’s hard not to go back. Someone else said that it takes your willpower away. It does. I’m having problems dealing with things. I am 55 and usually power-lift at the gym.

      Age has made me weak but I know that Seroquel XR decreases testosterone production and makes me fat. I can deal with the age induced weakness, not well. But to take drugs that increase that is crazy. I’m on a lot of other meds. But low seroquel is difficult to live with. I just hope I can drop the 150mg and be seroquel free. I hope these withdrawal symptoms get easier to deal with.

  • Eranga September 9, 2014, 5:40 pm

    I quit cold turkey about 2 months ago. I feel like I’ve been shot in the head.
    My muscles ache. I have these manic anger episodes. I feel agitated.
    I feel sexually frustrated. My testicles hurt so bad. I feel like someone is trying to rip them off. I can’t sleep. I am forced to take either NyQuil or Benadryl as a sleeping aid. I look like a fool right now. I wish I tapered off.
    To make it worse I quit Prozac cold turkey at the same time. I can’t concentrate to save my life. I just can’t take this anymore. I had an anxiety attack and had to be hospitalized.

  • Alice September 9, 2014, 7:48 am

    ohmygosh.. I just thought I had a bad bout of food poisoning. I feel so sorry for all of you who have been on this drug for what must seem an eternity! My last visit to a psychiatric institution landed me under a section 30 here in New Zealand – which is a community outpatient treatment order that can last for up to six months and requires me to legally take my medication.

    But shhhhhhhhhhhhh don’t tell anyone, last night I decided I don’t like the way this drug makes my head foggy, I don’t like the weight gain, and I don’t like the nightmares; so I didn’t take my relatively small dose of 200mg. I have had constant diarrhea (in the middle of a bush walk – yeah I had to use a sock.. use your imagination), my shaking is uncontrollable, and I am sweating like I never have before.

    Mentally I feel like magic so I think I am going to put up with the nausea and sweats for now; I’m just praying its not going to get worse but from what you guys are saying (and this is only day 1 for me) I get the feeling its not going to get any better. I definitely would have gone with the tapering method had I done a bit of reading about coming off this awful drug. Good luck to everyone else who is planning to come of q! peace :)

    • Kara Healey October 30, 2014, 2:09 pm

      I am in New Zealand as well. I was diagnosed with Fibromyalgia about 3 years ago and have been on a mixed cocktail of drugs and medication for over 4 yrs. I used to take codeine and tramadol everyday just to be able to deal with pain so I could get out of bed in the mornings. I have been using zopiclone and or quitiapine most nights to sleep. I have run out of both of my scripts and this is the first night I have been without help to sleep. I was wondering why I felt so itchy all over my body and am having intense insomnia.

      So I googled withdrawal symptoms and found this page. I was not intentionally trying to stop taking these meds as I love the feeling of being able to sleep that hey give me. reading other peoples experiences with this drug has made me think I should stop. A lot of the symptoms that people are describing sound exactly like Fibromyalgia symptoms: pain, fatigue, brain fog etc. But I was experiencing these symptoms before I started taking quitiapine.

      I am wondering if the intitial fibro symptoms were actually caused by codeine and tramadol addiction. I had reconstructive surgery to repair a torn ligament in my knee about 4 yrs ago and was prescribed tramadol for post surgery pain relief. My health and quality of life has pretty much gone down hill since then. I asked my doctor at the time of my fibro diagnosis if it could possibly be caused by the dependence on pain killers and was assured that it wasnt related. I am seriously doubting that advice now.

      I am totally dependent on medication now just to function but sometimes I am barely functioning at all, spending days in bed, lack of desire for anything, depression etc. Then I will have a few days where I am highly functioning when I have remembered to take all my meds. It’s making me crazy right now.. I wish I could sleep without drugs.

  • Sandy September 8, 2014, 7:46 am

    Day 12 and I am coming out of my Seroquel withdrawal with the help of Vistaril for the itching and anxiety and Ambien for sleep. I also take Ropinerole for Restless Leg Syndrome. These three drugs have counter acted the miserable withdrawal side affects of this bear of a drug, Seroquel. My problems now are mental again. I have come out of Bipolar Depression and and facing a quickly rising onset of mania.

    It is time to clear my body of the other drugs that I have found to make me feel comfortable in my skin and try another round of drugs to treat my insanity. I fear that I will lose it this time and not come out of it. If only I could feel good in my skin and feel balanced in my brain and be able to function in the world around me and be a valuable employee. Can I do this myself without this powerful mind drugs that ruin our neuro and digestive tract systems?

  • Kerrie September 4, 2014, 7:39 am

    I am 25 years old, and have suffered from severe mental illness since the age of 16. Over long and numerous stays at psychiatric institutions, I have wasted 2 years of my life behind locked doors restricted to a ward. I have been prescribed 600Mg of Seroquel XR by my psychiatrist for 5 years now.

    I have never wanted to decrease my dosage or come of this drug before, as it has been very beneficial to the slow learning curve of adjusting to living and surviving with my mental Illness. It has been somewhat of a lifesaver. The side effects of taking this medication for me were massive weight gain, tiredness/lethargy, and decreased mental functioning.

    I have come to a point now though, where these negative effects are far outweighing the good. Medication is merely a stepping stone, not something to live on forever. I believe, though it will be extremely difficult, that I can go on managing without taking this medication.

    As of Monday I have stopped taking my daily 600Mg of Seroquel XR. It has been 4 days so far and feels like an eternity. Initial withdrawal symptoms for Day 1 and Day 2 were very much flu like, with a running nose, constant sweating, headaches, mental foggyness and little to no sleep.

    Day 3 and the nausea and vomiting began. I threw up for 9 hours every half hour to hour, until I gave in and visited the doctor for a Maxalon injection. It relaxes the stomach muscles and the body so you stop vomiting. Alas I would be safe from further vomiting for the night.

    As well as nausea and vomiting I have a constant migraine and my head gets so hot it feels like it is on fire, accompanied by hot and cold sweats and dizziness quite similar to a fever. I still can’t sleep. Only managing a few mere hours if that amidst constant waking up, tossing and turning, being either too hot or too cold and tumultuous dreams.

    Day 4 and the Maxalon Injection has worn off. I feel constantly nauseous and have resumed vomiting. Headache is still going strong and feels like it is only getting worse. Hot and cold sweats and dizziness still accompanying everything else. I have never felt so bad in my life. It is unbearable constant suffering.

    I wanted a faster result than weaning myself off though so I guess this is my punishment.

    I will NOT lose my resolve

  • Sancy September 2, 2014, 12:37 pm

    Day six, diarrhea for 24 hours. I am sleeping, thanks to Hydroxyzine (Vistaril) an antihistamine and anti-anxiety drug. It has been a life-saver. Controls the nausea, itchiness, and general anxiety of Seroquel withdrawal. Seroquel has been the worst withdrawal in the way of flu like symptoms that keep you in bed but unable to sleep through the pain of it.

    Again, hydroxyzine has been the saving grace here. I could not have done it on my own. I am convinced that Seroquel prevents the brain’s cognitive function and disturbs normal sleep and digestive tract functions. A BAD DRUG.

  • Jack September 2, 2014, 11:09 am

    Still trying to get well 3 weeks last dose very sick can not believe how sick I am and getting sicker not better

  • Sandy August 29, 2014, 5:09 pm

    Thank God that I have found this website. Five days ago, I took my last dose of Seroquel. I started at 400 mg four years ago and have been on 300 for at least three years. I am one that cannot take less than 300 or my body goes into an extreme restlessness that is unbearable. I quit cold turkey.

    My reasons to quit were that: 1) I could not keep a job. My brain does things that I cannot control or understand. 2) I cannot urinate in the morning. Takes at least 15 or 20 minutes to eliminate. 3) I cannot swallow or breathe when I wake up. My mouth is dry all the way to my esophagus and I am unable to talk for about three hours after waking. 4) Weight gain 20 pounds. That said, the withdrawal has been something completely unexpected, so I am thankful for this website. My doctor insists that I go back onto the meds (Lithium and Seroquel for bi-polar I.)

    I quit the Lithium with no physical problems. The Seroquel, however, is causing insomnia, rapid weight lose (ten pounds in five days), head ache, nausea, body aches, waking every two hours, and a mental “flushing” of bad memories. Hot and cold flashes. Irritability. A pained expression on my face. I am unable to urinate or eliminate normally. At first, I thought that I would die and that I needed to go to emergency. That has subsided. I am waiting for the vomiting to start.

    This is day six. I cannot eat or sleep. The mental fogginess and blurry vision even with glasses is what made me stop this drug. I am 61 and cannot afford to die on this drug. Now that I have read the side effects in depth, I cannot believe that any physician would prescribe this drug to another human being. When I read that the VA has spent billions on prescriptions for this drug, I am enraged. Why subject our soldiers to this hell? This drug could sent anyone over the edge to suicide.

    • Sarah December 6, 2014, 9:04 pm

      You are 100% exactly right!!!! I have literally just gone through the worst time of my life the past 3 weeks. All while trying to raise my 3 year old… on my own. I thought I was going to die. I was a vegetable on my sofa and couldn’t move. The scariest thing of my life coming off this HORRIFIC drug. Thank God for Homeopathic and Naturopaths. Just within two days I feel like a completely different person. One day at a time… the natural way. I will never trust this health care system again.

      • Donna January 21, 2016, 8:40 pm

        Sarah, Can you please contact me about using homeopathic and Naturopaths helped you get off of Seroquel? I have tried multiple times to get off of this medication and ended up in the hospital and on more meds. I do go to a naturopath and a homeopath but obviously they don’t know what your doctors know. Please contact me… donnaciaccio[AT]msn[dot]com.

        • Dee June 1, 2016, 2:44 am

          I’d also love to know the homeopathic remedies you were given by your Naturopath to enable you to discontinue Seroquel… and quell the horrible withdrawal effects. Can you please share? Thanks so much.

          • BeenthereDonethat July 14, 2016, 4:12 am

            I really don’t like these homeopathic sales pitches on here. If they really worked the world would know about them. I am willing to bet anything you have a monetary gain in promoting them here.

  • John August 28, 2014, 11:24 pm

    I’ve come off 1500Mg in the span of about 5 weeks and have realized only a few real symptoms. I have a lot of trouble sleeping. I had intense nausea and vomiting for about 48 hours. And the biggest thing is I’ve lost about 22 pounds and don’t have that great of an appetite. Which really doesn’t help that I’m a 3 sport athlete. I have a lot less energy at football practices and games.

    However I find it easier to wake up and get going places. I feel better on the inside knowing I am now off all my meds. Seroquel, Trazodone, Zoloft, and Depakote. I was on over 3000Mg of medicine just about two months ago and now am completely off. Just want to let anyone know who is suffering that it does end and it gets so much better.

  • Sue August 28, 2014, 4:00 am

    I take 200 mg time released. I have been taking it for a couple of years, and before that risperdal for many years. I have gained a tremendous amount of weight from these medicines (although my bp and all that are ok). I have diagnoses of schizoaffective disorder and borderline personality disorder. I do not want stop seroquel because it has saved my life.

    I cannot function without it, because of hallucinations, agitation, panic attacks and wanting to cut. Because of seroquel I finished my graduate degree. Yes, the wait gain will shorten my life. The seroquel may also damage my live. I do have some signs of tardive dyskensia. But, There is such a thing as quality over quantity of life. I have been mentally ill since young adulthood, and I am just passed middle age now.

    I have been in psych wards 8 times. Since seroquel (along with all the other medications I take) allows me to have some sort of life, then I will go with it. Also, the antipsychotics in decades past were much much worse than seroquel for side effects.

  • cherie August 27, 2014, 5:14 pm

    Hi, I have been on serequel 300mg for 4yrs and quit cold turkey. I have had vomiting, diarriha, trouble sleeping, can’t eat or drink, the smell of food makes me vomit, my bones ache, headache I lost 10lbs in 10 days so I had to start the medication again and taper off slowly. I couldn’t handle the withdrawals.

    • Sandy August 29, 2014, 5:15 pm

      How are you today, Cherie? It is two days later. How many days have you been detoxing? The pharmacist tried to tell me about half-lives of drugs which I did not understand. Hope you are feeling better. You give me hope.

      • Dave February 17, 2016, 4:09 pm

        Half life of a drug is how long it takes for your body to reduce a drug to half. So if you took 10mg of a drug and 10 hours later you had 5mg left in your blood then that means the Half Life is 10 hours. The longer the half life the longer it takes to leave the body. I would read up before taking any drug whether it’s legal or not.

        Me myself would never take anything without knowing everything about it. Even then I still took most substances regardless. Never trust a Doctor trust me. When you educate yourself about drugs you will come to find out that you know more about the drug you are taking than your own doctor does.

        I have caught doctors not knowing the answer to questions about a drug they were prescribing me. I found that crazy but in reality all the doctors know about the drug is what the drug manufacturer tells them in a lot of cases.

      • Marley March 22, 2016, 12:55 pm

        Hi Sandy. March 2016. To try and simplify 1/2 lives: A dose of 100mg may have a 1/2 life of 8 hours so in 8 hours plasma (blood) levels have dropped to 50mg (1/2 of 100mg) in a further 8 hours it drops to 25mgs and so on 12.5mg, 6.25mg, 3.125mg. This would be said to have 5 half lives. Hope this helps.

  • jevonna August 27, 2014, 3:01 am

    I’m going through withdrawal and it is not nothing nice vomiting, nausea, headache, dizziness, blurred vision, unable to do day to day functions it’s a real mess

  • rick August 1, 2014, 8:37 pm

    I have been on Seroquel for three or four years, Things got bad around the first of the year and I could no longer get a perscription or meds from Astrazeneca anymore. I keep reducing the pills I had left and then ended up with a half ass medical insurance. You know what on I am talking about. Saw a doctor and he doubled the 300mg to twice a day. I was tired, Hungry and getting fat. Well I can see that I will be without again so its time to dump all meds and let life do what it has to do. Seroquel is a dangerous drug and the doctor says dont stop taking it. Well I am down to 50 mg piece a day before sleep. I already tried to just stop but no sleep. Why do american doctors perscribe so much crap to us. They get paid to and your health is not the number one concern. Healthy people are not a profitable thing and money is. If I die I dont care at 59 years old as I am not going to keep taking more and more meds to stay alive so they say. All I can do is let God decide what to do with me. DOnt let your family or friends let the medical community make them sick for profit. Go to another country for medical advice thats is not like americas sorry deadly healthcare providers. People with no insurance live longer as they dont have access to deadly perscriptions to make them sicker as life goes on.

    • Skylark November 26, 2014, 1:05 am

      Hey Guys, I’m on 900mg for bipolar and I kinda love the stuff – only because I’m so better on in than I am without it. Just recently though, I’ve missed a few doses – like I’ve ran out or whatever… The withdrawal effects are so bad that I’m literally unable to function in any way at all. That’s from just missing 1 dose. It is unbearable. Massive sweating, excessive muscle pain, paranoia, constant vomiting, insomnia and worst of all suicidal tendencies. The worst of it is that the drug really works and helps me live a somewhat normal life – but missing one dose really really messes it all up… any help on alternatives would be greatly received.

    • Thinh August 22, 2016, 5:00 am

      Like you, I have had seroquel for 4 years now. Last 4 months reduced to 50mg / 4 nights = over 10mg only a night. Still sleep well. But this week non sleep when full quit. Trying to deal for more coming days.

  • Kayleigh July 31, 2014, 5:01 pm

    I was given a misdiagnosis of borderline personality disorder a year and a half ago and I found out about a month ago that I actually have PTSD. I was given 500mg of Seroquel to start of with and I have been struggling constantly with the effects of this evil drug. I have dropped out of college twice due to how much this drug makes me sleep and lack of concentration and there was a phase of about 2 months where I was embarrassed to leave the house due to the harsh muscle spasms seroquel caused. I also have tried 4 times to quit this drug and the withdrawal symptoms have been atrocious. I have now gone two days cold turkey and I am feeling positive that this time I will succeed and get this poison out of my body.

    • Matthew November 30, 2014, 11:52 am

      Kayleigh, Sorry to hear you have PTSD. I have been seeing an EMDR Therapist for my PTSD, and getting remarkable results quite quickly. I have gone from 4-5 nightmares every night to 1 every 3weeks, a remarkable change given years of other therapies have not worked. The concept sounds like new age tree hugging mumbojumbo but it is well research. I am starting the decrease in my Seroquel, and 2 days in things have been unsettled, overly emotional and fragile. Thank you to everyone.

  • Victoria July 14, 2014, 6:12 pm

    And YES your body dont need that “thing” in your brain I suggest you for maintaining this thing in your brain be careful what you eat ( less dead food -like the junk food more more fruits and vegetables) Please check about ‘the role of adrenal glands =which main role is to produce hormones for balancing the anxiety and about thyroid=which if doesn’t produce the necessary amount calcium appears depression feelings ‘) Try to use more vitamins for your brain s function BUT what you put in your body is ESSENTIALLY! Peace!

  • Victoria July 14, 2014, 5:59 pm

    Bodies are different What I have learnt from my own experiences and the other s one is that no doctor has no idea which quantity of serotonin or other neurotransmitters is lack in your brain so they do estimate as the entire pharmacy dose when they do create pills So if for you example you have been taking 400 mg of Seroquel but your brain needs only 310 mg and you don’t know- the rest of the pill quantity is going to be itself side 0 effect -thus you feel more agitated or mania etc it s depend on each other person brain Plus if you have been functioned with a drug perfectly and when you took off cold turkey and had no side effects-means your doctor prescribed exactly what your brain needs in perfect quantity plus you didnt suffered from terrible side effects which eventually became toxins in your body and once you stopped it your body is of toxicity and it doesn’t have the proper power in a short time to get them off immediately Another thing if you withdrew Seroquel and you feel great mean your brain chemistry balance is so perfect that the body doesn’t feel abruptly the lack with the Seroquel Another possibility is that you have been taken small quantity of Seroquel for shorter time so the body didn t intoxicate itself with the toxin of it and when you withdrew because probably you have a strong body constitution But remeber there are people who suffer from withdrew s and other not and you are one of the lucky one !!! Wish all the best and Love !

  • Sam de Thierry July 14, 2014, 6:47 am

    Before I go into this, I want to say one thing, I am in no way gloating or trivializing what seems to be an awful experience I am trying to find some information for my experience. I was diagnosed about 4 years ago with bipolar 2 (not sure about that in the first place) and was put on Lamictal and Quetiapine. I had no problem with the Lamictal but the Quetiapine has been just evil. I had all the normal side effects of really bad lethargy, weight gain etc and just got sick of it so decided last week that I needed to come off it. I did all the research about coming off and all the horror stories about withdrawal but decided that I would just do it cold turkey I mean if it go to bad then I would just revisit it. Well I am a week down now and the only side effect that I have had was a bit of insomnia, other than that, absolutely nothing. I kept waiting for things to hit me, but nothing at all. I really don’t know why but the only thing that I can put it down to is that about 5 years ago I had serious addiction to codeine and eventually got sick of the toll it was taking and went cold turkey off that and had terrible withdrawal which lasted 3 days. I know this might sound strange but because I went through that, is it possible that my body no longer has the ‘thing’ in me to go through withdrawal. Anyone with ideas?

    • Megan December 22, 2014, 3:07 am

      That’s how I feel my titration is going. I am taking it very slooowww and gradually going down to zero the next two months. I have every bad side effect. My psychiatrist said I’m bipolar too (don’t be so complacent or believe everything the “experts” tell you about what to do. It’s your body. Your life. Your brain. They can go f*ck off). When I spoke slowly and calmly to the psychiatrist that I have an abusive, very dysfunctional living situation. No friends as I haven’t lived in this part for 12 years.

      I don’t fit in. It can feel isolating at time when no one around you listens to you and tries to get you or god forbid, just be nice. He told the seizure neurologist I needed a double dose of the lamictal because I’m “hypomanic.” Bull f*cking sh*t. I said that’s not going to happen, no thank you. I haven’t found a doctor to take me off seroquel, so I’m doing it myself, very slowly. Don’t let people run all over you because your “mental health is compromised.”

  • Nadia July 10, 2014, 5:53 pm

    I have been tapering myself off Seroquel for the past 6 weeks after 2.5 years on 25mg a night. It was prescribed for insomnia induced mania. I felt like it was my saving grace. Six weeks ago I decided I couldn’t take the weight gain any longer and didn’t want the possible side effects of diabetes so started to take half a night then going two nights without one night on! I started to exercise of a morning but the side effects kicked in, depression, lethargy, nausea, anxiety, sleeplessness, weight loss, (which wasn’t necessarily a bad thing) and then one day I got prickly heat and couldn’t sleep so took some Seroquel two nights in a row! OH MY GOD THE ITCHING since then has been unbearable! I have had all over body itching for the last two weeks! My doctor has told me to go back onto the Seroquel but I refuse to because I do not want to go through withdrawal again! Nobody told me this would happen. In the end because of such distress and not sleeping and getting manic again, the doctor has given me an itch cream and some over the counter sleeping tablets. The itching is still happening but it is bearable now am sleeping! I am hoping and praying this feeling like my skin is on fire with hot pins and needles will eventually stop! My last half a Quetiapine tablet was 8 days ago. I have found out form forums since 2008 that this is a withdrawal effect! And that I have also essentially been taking a anti-histamine for neary 2.5 years! I am now looking into alternative therapies to help rebalance my brain chemistry and find a more holistic way of balancing my moods! Never again will I take Quetiapine.

    • Angie May 8, 2015, 10:05 pm

      Nadia thank you SO MUCH for your post. I thought I was LOSING MY MIND WITH THE ITCHING. I was beginning to think I had bed bugs or scabies it has been so UNBEARABLE. I have been on only 25 mg for sleep for about 5 years now. My last dose was 7 days ago. I did not expect to have severe withdrawal on such a low dose. Was I wrong! I have barely slept since I stopped taking it. I burst into tears. I am hypersensitive and having mild hallucinations. OMG! I pray this doesn’t last much longer!

      • Eva May 16, 2015, 4:05 am

        I was on 50mg, then back down to 25 after researched that it was killing me… I got the “OK” to stop, and this ITCHING is so awful I’m not even sure what other side effects I have right now. I feel so obsessed with the itching I can’t even think. Irony…

    • Dave February 17, 2016, 3:58 pm

      25MG is an extremely low dose. I would suggest switching to diphenhydramine aka (Benadryl) at bedtime. A dose of 50mg should suffice and you may just want to try 25MG at first to see how it affects you. By the way if you have completely gotten off Seroquel let me know how long it took for the itching to stop. This is by far the worst symptom I had and one of the reasons I mentioned Benadryl. Hope all is well…

  • Jackie July 6, 2014, 12:14 am

    This is very useful information.

    I began Seroquel in 2007. My highest dose was 1500mg during psychosis in 2009.

    From 2009-2014 I tapered my dose down from 1500mg to 50mg a day. With the supervision of my psychiatrist.
    5 days ago I had my last dose. Wednesday was fine, then Thursday the withdrawal hit. I had no idea what I was in for.

    The nausea is the worst medical thing have experienced in my life. It’s relentless. This is awful, I wouldn’t wish it on my worst enemy.

    Seroquel is a serious drug. I would not have taken it if I had known this would happen.

    • Kristopher July 25, 2015, 8:40 pm

      The stomach pain is indeed relentless =( It’s been a month for me now and it hasn’t stopped. Stopping seroquel has just completely thrown my digestive system out of whack.

      • Rod December 30, 2015, 10:48 am

        Hi Kristopher :) Just wondering when you wrote this & whether you’ve gotten over these stomach pains. I am getting off this terrible Seroquel & have been getting the worst abdominal pains & pains in the guts. Hope you’re succeeding in getting off this horrendous drug!

    • BG September 23, 2015, 4:18 am

      I am coming off 200 mg of seroquel and 3 months later, I am down to 100 mg and the nausea is AWFUL! Has your nausea gone away? Wondering how long I have to suffer like this. It’s affecting my daily life which pisses me off to no end. I feel like I’ll never feel better.

      • Cathy February 10, 2016, 1:48 pm

        I too have quit cold turkey after 6 months of 100 mg. I have had several stomach scans, tests the works thinking I was having something other than withdrawal symptoms. I have been nauseated have been having sharp pain in the abdomen upper and lower with diarrhea and vomiting.

        I wish it would end. I have lost weight though since everyone says they have gained which is the only good thing about this for me. It has been an eye opening experience for me and now I ride it out. I pray we all get relief soon.