A 259-person multiple system atrophy survey found diagnosed neurogenic orthostatic hypotension in 41.7% of respondents, while another 40.0% had upright symptoms suspicious for nOH without a diagnosis and 21.2% reported never having upright blood pressure measured.1 The operational problem is simple: in MSA, low blood pressure on standing can be disabling, missed, and still undertreated …
ZzzQuil is an over-the-counter medication utilized most frequently to enhance sleep quality among individuals with allergies or the “common cold.” However, because ZzzQuil is a potent sleep aid, individuals without health problems sometimes use the medication to help manage insomnia. On occasion, ZzzQuil is even administered for the treatment of motion sickness and extrapyramidal symptoms …
Xanax (alprazolam) is a drug of the benzodiazepine class originally developed by Upjohn, a Michigan-based pharmaceutical company (now a subsidiary of Pfizer). In the United States, Xanax first received FDA approval for the treatment of panic disorder and hit the market as a prescription medication in 1981. It eventually received subsequent FDA approval for the …
ZzzQuil is an over-the-counter (OTC) sleep aid manufactured by Vicks (a subsidiary of Proctor & Gamble) that initially hit the market in 2012. When administered on an “as-needed” basis, ZzzQuil is thought to alleviate occasional bouts of insomnia and other sleep disturbances with minimal risk of abuse, addiction, and/or dependence – as compared to pharmaceutical …
Kratom (Mitragyna speciosa) is an evergreen tree from the Rubiaceae (coffee) family that produces leaves containing numerous psychoactive compounds, most notably including indole alkaloids: 7-hydroxymitragynine, mitraphylline, and mitragynine. When ingested by humans, the aforestated indole alkaloids significantly modulate CNS activity primarily via partial agonism of mu-opioid receptors (MORs). In addition, evidence from pharmacodynamic investigations suggests …
Ubiquinol is an electron-rich, highly-bioavailable, fully reduced form of coenzyme Q10 (CoQ10) that occurs naturally within all of our cells. When we’re young, the body is well-equipped to synthesize ubiquinone into ubiquinol (via Q Cycle reactions) which elicits an antioxidant effect to reduce free radicals and enhances cellular energy. However, biological aging interferes with a …
Belviq (Lorcaserin) is an anorectic medication manufactured by Arena Pharmaceuticals for the long-term management of obesity. As of 2012, the FDA approved lorcaserin to promote weight loss in adults with: BMIs exceeding 30 or BMIs exceeding 27 plus [at least] one weight-related medical comorbidity such as diabetes, hyperlipidemia, and/or hypertension. Upon administration, lorcaserin functions primarily …