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Latuda (Lurasidone) Withdrawal Symptoms + How Long Do They Last?

Latuda (Lurasidone) is a new atypical antipsychotic drug that is approved for the treatment of depressive episodes in bipolar disorder (type 1) as well as schizophrenia. It is considered a relatively new drug as it was just approved in 2013 to treat depressive episodes for people with bipolar I disorder. This drug is somewhat unique because it is among very few antipsychotics that are able to treat the depressive side of bipolar disorder.

Although this drug may work well for treating the depression in bipolar I patients, there is not yet substantial evidence proving that it also helps address manic episodes. For this reason, it is sometimes prescribed with lithium as it is known to help control mania. It also has been thought to work well at addressing both the negative symptoms as well as the cognitive symptoms (i.e. memory deficits) among individuals with schizophrenia.

It is thought to help learning and memory as a result of the effect it has on various serotonin receptors. Despite the fact that there is a lot of hype surrounding this new antipsychotic drug, it hasn’t been around long enough for an accurate evaluation; long-term effects are unknown. Most of the studies suggest that Latuda is well-tolerated with minimal side effects compared to other anitpsychotics.

However, just because it is a newer, trendy drug that is touted as having minimal side effects does not mean it is perfect. Many people will still have side effects with this drug and/or find it ineffective at managing their symptoms. A majority of people will try it for awhile, and end up having to face withdrawal symptoms.

Factors that influence Latuda (Lurasidone) withdrawal

As with any antipsychotic drug, there are going to be various factors that play a role in determining withdrawal symptoms. These key factors include: the time span over which you took the drug, your dosage, how quickly you withdrew, as well as other individual factors such as sensitivity to withdrawal.

1. Time Span

How long did you take Latuda? In general, the longer you take an antipsychotic drug, the more difficulty you are likely to have facing withdrawal. When you take an antipsychotic for a long period of time, your body and brain become accustomed to receiving the drug for everyday functioning.

If you take away the substance that you have been supplying your nervous system for an extended period, it is going to have difficulty functioning properly – leading to withdrawal symptoms. Individuals who took Latuda for only a short period of time are likely going to have a much easier time facing withdrawal and readjusting to normal functioning.

2. Dosage (20 mg to 160 mg)

How much Latuda were you taking on a daily basis? Individuals with schizophrenia tend to start at a dose of around 40 mg and then titrate up to a dose that provides symptom relief if the starting dose is inadequate. It can be taken from the starting dose of 40 mg all the way up to a maximum daily amount of 160 mg.

Individuals with bipolar depression typically take anywhere from 20 mg to 120 mg (the daily maximum). It should be noted that titrating upwards from the starting dosage is typically not necessary and doesn’t usually yield any additional benefit. With that said, when a person is taking a higher dose than average, the body can become tolerant to the extra strength of the drug. Withdrawal is thought to be longer-lasting and more severe if you took a higher dose.

3. Cold Turkey vs. Tapering

Despite the fact that many people claim that this drug has minimal discontinuation symptoms doesn’t mean that you should quit cold turkey. It is still relatively new and the jury is still out on how quickly you can come off of this drug. I would recommend conducting a gradual taper just like other antipsychotics.

A tapering protocol that you can use is cutting down by 10 mg every 2 weeks. So if you were on 40 mg, you could drop down to 30 mg after 2 weeks. By dropping at a rate of 10 mg every couple weeks, you are giving your nervous system a chance to gradually adjust to functioning with less of the drug. Tapering is thought to yield significantly less side effects than quitting cold turkey.

4. Individual Factors

It is also important to consider individual factors when coming off an antipsychotic. Some people may not experience many withdrawal symptoms, while others may be plagued with debilitating withdrawal effects for weeks (or months) following their last dose. Certain individuals are naturally more sensitive to withdrawal from drugs than others.

Various factors to consider include: amount of social support, whether you are taking other drugs, whether you are transitioning to another antipsychotic, and your daily habits. People who eat healthy, exercise, and get plenty of sleep may have an easier time recovering from withdrawal symptoms. Additionally people who are taking other drugs or transitioning to another anitpsychotic may not notice nearly as much of a withdrawal.

Latuda Withdrawal Symptoms: List of Possibilities

Below is a list of possible withdrawal symptoms that you may experience when discontinuing Latuda. Understand that you may not experience every symptom listed and that severity of the symptoms can differ based on the individual.

  • Anger: Various individuals have reported that they felt pretty grumpy during withdrawal from Latuda. This is an antipsychotic that tends to have somewhat of an antidepressant effect and works on serotonin. When coming off of it, your neurotransmitter levels may be lower than average, making individuals more prone to anger.
  • Anxiety: Some people experience pretty severe anxiety when they initially quit this drug. Some withdrawal accounts have stated that anxiety was their worst withdrawal symptom and persisted for a long period (in one case months) after the last dose.
  • Body aches: As with most antipsychotics, you may notice that your muscles feel especially achy and/or you may feel weakness as you come off of this drug. Experiencing muscle aches and feeling weak is likely due to your nervous system adjusting to not having the drug for functioning.
  • Concentration problems: Some people notice foggy thinking when they discontinue this medication. The concentration difficulties may be due to the fact that people are experiencing an array of physical side effects while coming off of the drug – which can be distracting. Additionally the cognitive benefits that a person experiences while taking the drug will subside during withdrawal.
  • Confusion: This drug is thought to improve cognition in some people who take it. When you come off of it, the improved cognition will likely subside. The combination of concentration and memory problems during withdrawal can contribute to a general state of confusion.
  • Depersonalization: You may feel unlike your natural self during the withdrawal process. You may feel like a zombie and/or as if your normal self has left your body. This is largely due to changes in neurotransmitters and brain activity as a result of withdrawal. Over time, you should return to feeling like your normal self again.
  • Depression: It is very common to feel depressed during withdrawal from Latuda. In part this may be due to the fact that your brain is no longer receiving the same degree of dopamine and serotonin regulation that the drug provided. When you stop taking it, you may feel even more depressed than before you started taking it. It will likely take some time for your brain functioning to adjust.
  • Dizziness: One of the most common withdrawal effects from any psychiatric medication is that of dizziness. Do not be surprised if you discontinue this drug and notice that you feel extremely dizzy during the first few weeks following your last dose.
  • Fatigue: Some people experience pretty significant fatigue when they stop taking this drug. The fatigue is usually a result of your brain attempting to reestablish normal, sober functioning. The withdrawal can be mentally draining and leave people feeling lethargy.
  • Hallucinations: During withdrawal, it is possible to experience symptoms of psychosis. One of the hallmark symptoms of psychosis is that of hallucinations. Although this it is not common to hallucinate during withdrawal, it is possible as your dopamine activity readjusts.
  • Headache: Perhaps one of the worst symptoms of Latuda withdrawal is that of headaches. Some individuals have reported severe pressure headaches and/or migraines for weeks following their last dose. Do your best to relax, stay hydrated, and consider over-the-counter headache relief if they are substantial.
  • Insomnia: Another withdrawal symptom that people experience is insomnia or the inability to fall asleep at night. This may be severe for the first few weeks of withdrawal, but eventually your sleep cycle should correct itself and this will subside.
  • Memory problems: This drug is thought to help improve cognition and deficits that people experience as a result of schizophrenia. When you come off of it, you may notice that your memory isn’t as good as it was while you took the drug. In some cases your memory may be worse than before you took your first dose of the drug. Unless you had major memory deficits before you took the drug, you should experience full recovery in memory functioning.
  • Mood swings: This is a drug that affects dopamine, serotonin, and adrenergic receptors in the brain. During withdrawal a person may experience abnormal functioning from the receptors affected by the drug – which could be the culprit for mood swings. One minute you may feel hopeful for the future, the next minute completely hopeless and depressed. Just know that mood swings should eventually stabilize (assuming you are non-bipolar).
  • Nausea: Another fairly common symptom that people experience is that of nausea. If this becomes severe enough it may lead to vomiting. This can be reduced by conducting a gradual taper off of the drug. Quitting cold turkey is thought to lead to more significant nausea.
  • Psychosis: Researchers have found that withdrawal from antipsychotics can cause psychosis. In other words, even if you don’t have schizophrenia, but were on an antipsychotic medication like Latuda, you could end up experiencing temporary psychosis. Additionally people who have been diagnosed with schizophrenia may be experiencing a relapse in symptoms.
  • Racing thoughts: Some people have reported experiencing changes in thought patterns upon withdrawal. You may notice that you experience more racing thoughts (not to be confused with mania) and/or unpleasant, intrusive thoughts.
  • Restlessness: You may feel a general sense of restlessness or inability to sit still. Restlessness is often a symptom that occurs when serotonin and dopamine levels are altered. As time passes, you should eventually feel more naturally calm.
  • Sleep changes: Your sleep pattern may become temporarily altered during withdrawal. Many people report that while they are on Latuda they notice a trend of tiredness and others have difficulty getting restful sleep. When you come off of the drug, your natural sleep cycle may require some time to reset itself.
  • Suicidal thinking: Since this medication tends to provide somewhat of an antidepressant effect, coming off of it may lead a person to feel depressed and suicidal. If you feel suicidal, understand that it may be in part due to withdrawal. Seek help from a therapist if you are unable to cope with this feeling.
  • Sweating: You may experience heavy sweats throughout the day and/or wake up with night sweats. Sweating is a common symptom of withdrawal and in part is due to your nervous system adjusting itself and can serve as a natural detoxification response.
  • Tremors: Antipsychotic withdrawal can lead a person to shake uncontrollably or have “tremors.” You may notice that you shake uncontrollably in the hand region and/or throughout the body.
  • Vision changes: You may notice changes in your vision when you come off this drug. The changes are unlikely to be permanent, but you may experience temporary blurs or alterations. These will eventually return to normal with enough time off of the drug.
  • Weight loss: In general, Latuda is considered an antipsychotic that doesn’t tend to lead to drastic weight gain.  Some people experience significant increases in appetite (and craving for carbohydrates) when they are on Latuda. When they stop taking it, their appetite returns to normal and they lose the weight that they gained. Don’t expect immediate weight loss, but just know that you will eventually lose the weight that you packed on.

Latuda Withdrawal Duration: How long does it last?

There is no exact timeline that can be followed when withdrawing from Latuda. The severity of symptoms that you experience as well as the duration for which they persist will be based entirely on individual circumstances. The drug itself has a half life of 18 hours, meaning it will be entirely cleared from your body within an estimated 126 hours (less than 6 days). However, just because the drug is cleared from the body within a couple of days doesn’t mean that withdrawal is immediately over.

Most withdrawal symptoms start after the drug has been fully cleared from the body. Common reported symptoms from antipsychotic withdrawal include: headaches, dizziness, low energy, and changes in mood. Some people may not notice many withdrawal symptoms from Latuda, while others may have difficult, protracted withdrawals that last for weeks, or in more extreme cases, months.

Although withdrawal symptoms may last for an extended period of time, do your best to engage in healthy habits. Getting proper rest, eating healthy, socializing, and getting light exercise can go a long way towards repairing the nervous system.  If you have gone through withdrawal from Latuda, feel free to share your experience in the comments section below, you may really help another person going through the same journey.

Unfortunately this is a relatively brand new drug and there isn’t much literature surrounding its discontinuation and withdrawal symptoms, so any additional insight that can be provided from those who have been on this drug is appreciated.

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{ 146 comments… add one }
  • Shann March 15, 2018, 12:53 am

    I’ve been on Latuda for about three months. Took 40mg, went up to 60, couldn’t handle the nausea, went back down to 40 and then went to 20mg for three weeks before stopping. The nausea was hit or miss. I didn’t like how numb this made me feel compared to all the medications I’ve been taking prior.

    My libido/ sex drive was dead which made me feel irritable. I felt like I was losing my personality. THAT being said, this drug worked well for my depression. It just amped up my anxiety really bad. I’m about two weeks off Latuda and I’m having mild depression, extreme bouts of anger and tiredness.

  • Mike March 9, 2018, 2:14 pm

    I wanted to share my experience for others going through this. I was on 80mg of Latuda for 6 weeks. My doctor didn’t properly taper me off the drug and after a week of stopping the medicine I started to experience withdrawal symptoms. Insomnia, tremors, anxiety, flu like symptoms and nausea.

    After 4 days of not sleeping I went to the ER. They gave me Valium and it did nothing for my symptoms. I was eventually admitted to the hospital. With the help of treatment the withdrawal subsided after 2 weeks.

    It’s been a month now and most of the symptoms are gone except I’m still having trouble sleeping. This was a nightmare I missed a lot of work and had to go on FML. To those going thru this I hope that you recover quickly and don’t experience this. Good luck.

  • Steven Michael February 20, 2018, 3:54 pm

    Ugh. I’m on day 6 of a taper (10 MG down to 5) of this stuff and it’s miserable. I was on 10 MG for 2.5 years, but once again my insurance company won’t cover it. This has happened to me twice now, so I just can’t deal with the drama and expense of this drug.

    It worked fine for me, but I was using it for an off-label use to combat non-bipolar depression along with Lexapro. So, with my doctor’s consent, I’m trying to wean myself off.

    It has an 18 hour half life, so I thought that by day six I’d be over the worst, but it seems that the wild ride is just beginning. What a drag to have shackled myself to this strong drug. I’m nauseated, clammy, my skin tingles, my head is killing me and I have no energy.

    Appetite ranges from ravenous to non-existent. It wouldn’t be so bad if I didn’t have a mortgage to pay and a job to perform in. You can’t exactly tell your co-workers that you’re temporarily insane because you’re coming off of an anti-psychotic drug.

    And this is just the taper! WTF is going to happen when I go cold? Ridiculous.

    • Steven Michael March 12, 2018, 5:42 pm

      Well… I thought I’d provide an update. It seems that day 6 is the worst day for me, for whatever reason. Because right after I posted my post above, the symptoms seemed to decrease markedly on day 7 onward. Since then, I’ve been reducing gradually, but fairly aggressively.

      After going down to 5MG (quarter of a pill), for about two weeks, I decided to start taking the quarter pill on an empty stomach, because theoretically this would reduce my body’s uptake of the drug, in effect reducing down from a quarter to something less.

      I did this for a week and noticed some cessation symptoms, but it wasn’t bad. After this I quit. I’m now on day 4 of no Latuda and, while I definitely feel I’m going through an adjustment, it’s not as bad as it was when I was reducing from 10 to 5 MG.

      I still have a couple more days until the dreaded day 6, but am cautiously optimistic.

      • Steven Michael March 21, 2018, 3:54 pm

        Ok…here’s my two week update. Once again, on day 6 I felt a minor anxiety spike but then it rapidly diminished. It’s been pretty easy, actually. Much easier than Zyprexa which I was on only for a short time, but was hell to clear out of my system. Oddly, even though I took the Latuda to assist in sleeping, I seem to have had little trouble with insomnia when decreasing and quitting. I’m glad I’m done.

        • Fabulous March 21, 2018, 6:07 pm

          Thank you so much for sharing, Steven. I plan to start taper of in June. I now feel less anxious and more optimistic. The information you’ve provided is much appreciated.

  • Jennifer February 18, 2018, 4:59 am

    I have been on Latuda for three years at 40mg. It was a great help with bipolar depression and I feel it helped be alcohol free during its use. I’m an alcoholic. The last year I developed terrible side effects. Extreme anxiety, Felt like I needed to leave my body at any cost. Lost my love for life and was numb.

    Isn’t from 120lbs to 170. I was so itchy. I tried to stop 6 months but the withdrawal was worse than those I have felt from alcohol. The effects lasted for two weeks before I gave up. I’m now quitting for the second time. I cut my pill in half for5 days and now have been off Latuda for a week. The withdrawal started as soon as I reduced my dose to 20mg.

    For the past four days I have been extremely nauseous with vomiting. I have had a horrible headache that feels like sinus pressure and it’s difficult for me to relieve the pain with aspirin her medication. My itching is worse than ever before and I am dizzy and have very low blood pressure.

    Yesterday I slept the whole day I was so tired I could not even think about getting up out of bed. I am surprised I have the energy to write this post. This time I’m not going to quit… I’m determined to stay off Latuda.

    Even though I am terribly sick at my stomach, I have noticed since quitting Latuda that food tastes better and I am feeling emotions I have not felt for a long time. I think Latuda is an evil drug and I wish I had never taken it. Good luck to anybody out there who is on it. Hang in there.

  • anonymous February 8, 2018, 9:45 pm

    Andy, I quit 100mg of Latuda, 1200 mg of Lithium, 10 mg of Lexapro, 10 mg of Propranolol 2X a day, and Risperidone (injection/shot/consta) of 37.5 mg every 2 weeks because I had gained over 100 lbs than what I used to weigh before psychiatric medication–255lbs at 5’8.25. I am a male, 27 yrs old.

    I quit last April 2017. Withdrawals were horrible. I experienced nausea, severe headaches, trembling, heart palpitations, cold sweats, exhaustion -literally, waking up, eating, falling asleep, waking up, eating, falling asleep… only sent out to buy groceries, and maintained my hygiene.

    My worst withdrawals lasted about 7 weeks. Last night was the worst night. I almost went back on medications b/c I could not stand it. I did not. When I woke up, something felt different. And I went from 255 to around 225 by just eating and falling asleep.

    I then used the south beach diet–something my urologist had recommended since mid 2014, and am now down to around 160 lbs, my spine has decompressed and I am now 5’10 and 7/8. Waist size went from 40 t0 30. I still experience difficulty maintaining focus. from time to time, but things are much better now because I am able to analyze my situation and my vision has improved so I can read books again.

    There is a “way” through the difficult situation. Please do not give up on your spouse. I wish you both the best.

  • Andy February 5, 2018, 9:56 pm

    My wife has been taking 20mg for approximately a year and a half. It has done wonders for her. Due to a change in our insurance status she was forced to stop taking it because it is expensive. Her Dr started tapering her off 3 months ago. She got down to a quarter of a pill, and yes we were cutting them. She started experiencing equilibrium problems, concentration problems and extreme nausea with some vomiting.

    Her Dr told her to just stop taking it. She did, and OMG! The nausea and vomiting are out of control. Its only been 5 days since she stopped. She has been at the ER twice in 2 days because the vomiting and nausea are so bad. Can’t eat, can’t drink anything. I have never in my life seen someone so sick before. People be careful, this is a powerful drug with horrible withdrawal symptoms.

  • Nancy Gordon December 19, 2017, 9:32 pm

    I only took Latuda for a little over a month. I was taking it for clinical/treatment resistant depression. My psychiatrist gave me samples, but not enough to last until my next appointment. I didn’t notice until I was almost out. My insurance company rejected the request for a prescription, so I went cold turkey.

    I have been having withdrawals for over a week & have never felt so horrible in my life, & I’m 51! Nausea, dizziness, worsening depression, bouts of anger. It really was starting to work after only 3 weeks, but if this is what coming off Latuda feels like, I never want to take it again.

  • Amy May 31, 2017, 4:40 pm

    Took Latuda for about a week and a half. Started noticing extreme nausea, restlessness, and anxiety within a week, after going from 20mg dose to 40mg dose. Decided to stop taking it, as I literally couldn’t keep down enough food to take it with.

    Haven’t taken it in 3 days now. Still feeling all 3 symptoms, but slowly to lesser extents. Went to urgent care and got Zofran for nausea, which helps a little. Hoping to feel better in a few days.

  • AMBER J April 15, 2017, 2:21 pm

    Been on Latuda 40mg for more than a year. A psychiatric nurse practitioner thought the med is expensive and I should be taken off. She had me titrate down 20mg for 3 days. I ended up with headaches, shakes, a feeling of motion sickness, vomiting, and allover body aches. I suggest a much lower dose. I have 120mg I cut down so it’s hard. Whoever said you can’t cut the pills is wrong. I’ve been cutting mine to save money the whole time.

  • Jonathan March 3, 2017, 11:58 pm

    I have been taking Latuda for 6 weeks and have decided to quite cold turkey. I am 26 years old and have been depressed most of my adult life, without any formal diagnosis until a little over a month ago. I was diagnosed with bipolar depression, which I was told just a few days ago by another doctor I am not bipolar.

    This may be important regarding what I experienced while taking Latuda. I was a part of an intensive inpatient program for those with severe depression. It was amazing in helping me deal with my depression, and I highly recommend anyone suffering from severe depression admit themselves to such a program.

    I was feeling much better after the first week, before being prescribed to Latuda. They started me at 20mg, and for the first week of taking it I didn’t notice much of a difference. There was a strange uneasy tiredness that came within roughly an hour after taking it, otherwise I felt normal. They decided to up my dosage up to 40mg.

    I started noticing a higher level of concentration, along with a few other side effects. I felt emotionally numb, and had a more difficult time connecting with new people. I also started feeling something I’ve scarcely ever experienced: anxiety. My entire life I’ve been socially outgoing, but Latuda made me feel like an introvert.

    Emotionally I still felt a bit depressed, but I thought it was because Latuda needed more time to build up in my system. I had been taking Latuda exclusively at night before bed, so I didn’t have the chance to experience the side effects for the first few hours of taking the drug. My doctor told me it may make me feel sleepy, but I started to notice more worrying side effects. It felt like I was having more trouble breathing, mostly with my breath being shorter.

    The anxiety started to get worse, and if I was still awake after an hour of taking Latuda, menial tasks felt difficult to carry out. It was strange for me, because as I stated earlier, I have never been an anxious person. After being on Latuda for 5 weeks, I felt that the negative side effects might be subsiding, and that Latuda might have finally built up in my system.

    I had gotten through a very difficult week of school while working full time, so I thought I would be less prone to the side effect of anxiety. I was going in to work the night shift at my job, which starts at 7pm, so I took Latuda a few hours prior at 4pm (I had been taking Latuda at 8-9pm daily). My reasoning was the negative side effects couldn’t be debilitating to the point where I couldn’t do my job, and because I had such a successful week at school, I would be less prone to anxiety.

    As I was getting ready to leave me house, I began to feel uneasy. On my way to work, I started to feel dizzy and a shortness of breath…I really didn’t want to be driving. When I got to the parking garage where I work, I was feeling progressively worse. I felt weak, and afraid to get out of my car.

    It felt like a forced march from the parking garage to the building where I work, and I was trying to just concentrate on breathing normally. My chest began to feel tight, and I could feel my face turning red. When I arrived at my unit, I realized that I was incapable of doing my job. I was dizzy, had developed a bad headache, I was out of energy, I felt like I wasn’t getting enough oxygen, my chest was tight, and I couldn’t focus.

    I also had and incredibly uneasy feeling, and I just wanted to curl up in the fetal position. At this point, I felt the same suicidal thoughts that plagued me me in the past creeping back. I was so unconformable and anxious and had just arrived at work, and it was getting worse. I was having a full-blown panic attack. My colleagues could tell that something was wrong.

    I told them how I felt in what words I could at the time, and that I was unable to drive. They offered to take me to the ER, and I obliged. I spent the night there, and if it wasn’t for the trazodone they gave me, I probably wouldn’t have slept that night. The panic attack lasted for roughly 5 hours, and as the debilitating anxiety subsided I started feeling restless.

    That episode has turned me completely off of Latuda. It was a real eye-opener. Feeling suicidal while on Latuda after 6 weeks of taking it was the nail in the coffin for me, set aside the panic attack. I am now fully motivated to seek alternative methods of tackling my depression and living a healthier lifestyle. I plan on joining a Yoga studio, and start eating a healthier diet.

    I’m not sure how the withdrawal is going to go for me, but so far after 2 days of not taking Latuda, I feel more lackadaisical than usual. I might check back in a few weeks with an update on my withdrawal.

  • Scott February 15, 2017, 10:23 pm

    I’m BP2 and the pdoc suggested I use this as my depresssive episodes were getting worse. 51 years old white male. I’ve tried a number of these things and they generally always end up awfully. I’ve only continued long term with Benzos due to high anxiety.

    This expensive “touted” designer/wonder drug caught my attention and I needed to get the depression down… so I started off on lower dose 20mg. for the first few days – no side effects and I thought, maybe this will help. I did also notice that my depression was much gone along with ideation thoughts. But… I was feeling increasingly “revved” up – which was provoking more anxiety.

    Couldn’t fall asleep couldn’t stay asleep and anxiety went through the roof, increasingly by days 4,5,6. I still stick with it as pdoc said must do. By days 7 and 8 when I finally quit it, I was a complete wreck of anxiety bag of nerves. It was devastating and I thought this cure is far worse than depressive episodes.

    Within 48 hours of quitting it, I started to get the full-blown issue of the tongue stuck in the back of the mouth issue that many have complained about here. It was around my epiglottis, and it was very frightening. It provoked the most scared thoughts in me, that this has taken a turn for the very worst.

    Not knowing what to do, I researched this intensely and found out that it was a common form of tardiness dyskinesia associated with UP 75% of users of this drug!! I was furious and scared and riddled with anxiety. Felt like I was in a permanent state of choking with the tongue dyskinesia issue. It was so frightening. My BP went wacky due to my anxiety as well.

    I read that this evil effect could be countered with Ativan/Lorazepam, which I demanded from my GP and he agreed. That largely worked. I’ve not been so scared in a long time.

    This drug has a Dark Side people. Please be very careful with it even on low doses over 2 weeks. It’s downright dangerous IMO. Don’t be tricked by the early days of use. It’s what comes later, that is truly disturbing. Best of luck.

  • Jess February 2, 2017, 5:17 pm

    I’m bipolar 2 and I have been on Latuda for a month and a half at 60 mg. I gained ten pounds in that course of time and I decided to quit cold turkey. It’s been a week since I quit and I sleep a lot, I am depressed and mildly suicidal. With some headaches.

    It’s not too bad for me since I feel more like myself and anyways I started out with depression so I’m trying to be more mindful. It is affecting my relationships since I tend to isolate myself but I’m going through a tough time of my life so I don’t care I’m just going to take it easy.

  • Beanie January 22, 2017, 12:33 am

    I was on Latuda for three months at 40 mg, tapered down to 20 mg for two days, then quit cold turkey after that. I figured that the withdrawals could not be any worse than actually being on this horrid drug. While on it, I didn’t care about anything…

    I couldn’t laugh, I couldn’t cry, and had terrible bouts of anxiety that would wake me up at 4 in the morning unable to go back to sleep. Also, time stands still while you are on Latuda and it is a struggle to think about anything other than when bedtime is coming… not that it matters because of the insomnia anyway.

    I have been off Latuda for 6 days now and the anxiety is still there, my sleep cycle is all screwed up, and I’m still feeling pretty flat. I wonder if I will ever feel like myself again. I wonder how long it will take for the anxiety to go away. Thinking of all of you who are going through hell with this drug and I pray we all get better.

    • Chris February 14, 2017, 8:46 pm

      I took Latuda for 7 months at 40 mg. It made me feel pretty good, but I was having a very hard time getting my insurance to cover it. With Obamacare on the chopping block, I decided to take myself off of it under doctor’s supervision. I tapered from 3/4 to 1/2 to nothing.

      I felt really good for the first few days. Now is day 5 and I feel so miserable. It doesn’t help that my grandmother just died last night and I have some other uncertainties in my life. But, without Latuda, everything seems so amplified. I feel super depressed and unhappy with everything and everyone.

      I can’t sleep through the night. Things that should make me happy made me sad. I am reading that things are about to get worse. I hope not. But, at least I am empowered and not waiting around until Trump takes me off of it by cutting Medicaid for individuals. I know things will eventually get better. For now, though, this sucks.

    • Scott February 15, 2017, 10:25 pm

      Beanie. My experience was not far different from yours. See my own note below. This thing has a very dark side to it… Scott

  • kay January 21, 2017, 2:35 pm

    I’ve been taking 60mg of latuda everyday for the past two years until I had to stop taking it because the doctors office made an error in scheduling. The withdrawal is something out of a horror book. Constant vomiting now for three days, aches, the no sleeping, and being very weak. I’ve have since got my medication back, but I’m still withdrawing at night. This medication has helped me a lot, but if I would have known that you can get withdraws, I know I wouldn’t have started them.

  • Susie January 1, 2017, 11:31 pm

    I was having restless leg syndrome. Weight gain around my middle, biting my tongue, severe ringing in my ears so I am stopping Latuda. I am so upset as what I was having may become permanent. I am stoping the awful drug Latuda. I am current taking 20 mil, down from 40, and I feel groggy. I’m hoping the withdrawals don’t get too bad. Wish me luck!

  • DJ December 17, 2016, 7:36 am

    Latuda has turned me into a raging b—-. I can’t control the rage, hostility and anxiety all rolled into one. I was never like this on any other medication. I’ve lost all my friends and my family hates me. I tried to explain about the medication but no one cares. It’s near the holidays and has caused me to feel really depressed, worse than before going on this medication. The doctor is trying to taper me off it, but the damage is done. Horrible headaches, insomnia and did I mention anger?! I used to be timid and anxious now I just don’t care and it has changed my personality.

  • ample waters December 16, 2016, 9:34 pm

    I have been on Latuda for a year. It caused weight gain, impotence, low testosterone, memory loss and tardive dyskinesia. I can’t go on like this. I don’t even know if my diagnosis is real or the symptoms were caused by long term alcohol and marijuana use. I have been tapering off the stuff very slowly since August (4 months) and am down to 20mg.

    I started at 80mg. I’ve been cutting up pills with a pill cutter. Now that I’m down to a quarter of a pill, I cannot cut them up further. After a month on the quarter pill, I will take a quarter pill every other day for a month and then every third day the final month.

    It’s going good so far. I’m quite lucky that I get this drug for free from the VA, 6 months at a time.

  • Lisa December 13, 2016, 12:28 am

    I have been on 80 mg for 6 years with the only side effect being fatigue. I have titrated dwon to 60 mg as of last week and have had no side effects. My goal is to go down to 40mgs and hope the fatigue goes away at that dosage.

  • Linda November 1, 2016, 1:21 pm

    I was put on Latuda 3 weeks ago. I was taking 120mgs of cymbalta and was functioning very well. I am diagnosed with depression as well as anxiety panic disorder. On Latuda I was nauseous irritable depressed and wanted to die because I felt so spaced out and angry. I stopped taking Latuda 3 days ago my body aches especially my neck and back. Today my fingers hurt. I have trouble sleeping when I was on it and off it. My anxieties have lessened. This drug should be illegal!

  • Charlene September 6, 2016, 2:45 am

    Has anyone had weird dreams when stopping Latuda?

    • DJ December 17, 2016, 7:41 am

      I have! They are very vivid and seem to distort my daily reality!

  • Anonymous August 1, 2016, 6:23 am

    I was on Latuda 10mg for 11 days. It was added to Lamictal (150mg) because of a manic episode that really scared me. Extreme dizziness (whenever I moved my head) was the only real issue I had with Latuda. It got better, but it did not go away. I staggered and almost fell quite a few times, prompting me to decide the benefit of the med wasn’t worth the risk.

    Tapering didn’t seem important since I used it such a short time and was taking just half of a pill at the lowest dosage available. Was I wrong! It has been two days since I stopped the 10mg dose and the migraines are horrible. I also have sweats and mood swings. 11 days on only a 10mg dose and this is the withdrawal?!

    I don’t want to deal with this. I’m going to take 5mg for a few weeks and then quit. BTW, as much as my headaches are “unbearable,” many of you are dealing with a lot more. This post isn’t meant to put myself at your level of issue. I’m posting to add my voice to the “taper extremely slowly” advice many of you have offered.

    If you’re on Latuda and thinking of getting off, don’t bet you will be one of the lucky ones with no withdrawal. Even someone on a tiny dose, like me, can get hit pretty hard.

    • Michelle August 26, 2016, 12:49 pm

      I am coming off a 60mg dose for two years. I was told to halve my dose for a few days. Big BIG mistake. I felt like I had the worst hangover of my life. Cold sweats. Vomiting. Last night I woke up shaking like I was having a seizure. I haven’t slept since and I can’t calm down. Took a Xanax and am waiting for it to hopefully help. If this is what the next few weeks look like then I am in for one hell of a time.

      • Michelle August 30, 2016, 6:17 pm

        Feeling fine. Instead of decreasing the dose I went cold turkey. I was almost incomprehensible and my husband nearly called 911 to have me committed. :( But since then I feel like a two year fog has been lifted off me! I never realized how strong this stuff is before I tried to quit. Hang in there!!!! You can feel like yourself again.

        • DJ December 17, 2016, 7:42 am

          Hope you’re doing better!

  • Wayne. July 25, 2016, 2:30 am

    I have been misdiagnosed as well and I was put on Latuda to taper off Seroquel. I have not had anything but bad symptoms from this whole misdiagnosis. I quit cold turkey after 4 months almost a week ago from 60mg. I wanted to jump out of my skin I was severely depressed and I have been having increased insomnia. And time stands almost still while feeling extremely restless.

    I feel much better since quitting but I’m afraid that the symptoms will come back in the form of withdrawal. I still have terrible insomnia but I have been taking melatonin and clonazepam to help. I would like to know if anyone else who has been misdiagnosed has had any similar issues?

    I have never been depressed but this experience has been the darkest time of my life. I am just hoping I can get away with going cold turkey since my body and mind rejected it anyways. Any help would be great if you have had similar experiences?

    • DJ December 17, 2016, 7:50 am

      I was misdiagnosed recently. I was locked out of my house one night, walked to my gym which is a 24 hour gym and some guy started following me. I hid behind a building and called the cops. He saw the police and ran into a neighborhood. The cops thought I was homeless and schizophrenic, which neither were true and I was sent for a 72 hour hold.

      I was angry, and the staff were hostile. I have bipolar and tried to clarify this, they said that’s not true. Eventually after a week things got sorted out and my doctor is trying to get me off the latuda the hospital put me on. I learned not to rely on cops!

  • Laura July 1, 2016, 9:49 pm

    Am in the process of dumping both Latuda and Paxil. On Paxil, I had a six-week titration downward and am still sick with the dreaded Paxil Flu. Latuda, I quit cold turkey, and I have to wonder if some of what I am attributing to Paxil is in fact the Latuda. I have a muscle spasm off and on in my right eye; it started when I started Latuda, and is gradually lessening with each day I am off the drug.

    I quit Latuda because I found the restlessness absolutely unbearable, along with the persistent notion that time is standing still. On Latuda, I was tormented by the notion that I could not fill my hours…not a nice combination with restless legs, body, arms. I’m off Latuda now, but the restlessness remains, albeit in smaller doses that I can reason with.

    One week of this misery…less than one week, actually…I try to turn my face to the sunshine, but this feels like forever.

  • Teri B Clark June 16, 2016, 6:50 pm

    Anyone experiencing stomach cramping as a withdrawal issue? My husband was slightly tapered from 80 to 40 to 20. He is very nauseated and has terrible pain in his upper bowel area.

  • Kirsten June 10, 2016, 3:09 pm

    I am currently on Latuda 80 mg and not diagnosed bipolar or schizophrenic. I have been diagnosed with severe depression and BPD. The BPD keeps making my idiot doctors think bipolar, but it takes time to diagnose that. Ever since I’ve been on Latuda I feel detached from my body. My depression and irritability has been off the charts for at least a solid 6 months.

    I sleep my days off away because I feel no point in getting out of bed. You could offer me something I’d love and I would find a way to stay in bed. This medication has ruined my life. I have been struggling with depression for 20 years now (since I was 10) and I know that this medication is causing more depression than ever.

    However, after reading through these virtual HORROR STORIES of withdrawal and weaning symptoms, I feel like my fight still lays before me. I’m seeing a doctor in 2 weeks and discussing weaning me off a medication that is prescribed for something I don’t even have. I’m terrified the suicidal thoughts will get worse. I’m so scared.

  • B.O. May 24, 2016, 9:22 am

    I was on 120mg for a year, gained 40lbs, craved carbs like an SOB. I quit cold turkey because it wasn’t helping my bipolar 1 anymore. It’s been 2 weeks and I have experienced all of the symptoms, especially sweating and severe insomnia (I take 2mg klonopin and 45mg restoril). I have even been taking Benadryl with my sleep meds and at best I get 4 hours of tossing and turning a night. Do not be confused with mania insomnia where you feel good and high without sleep; this is a terrible insomnia with racing thoughts. I hope it goes away soon.

    • Barbara August 11, 2016, 10:44 am

      I was only on Lutuda for 3 months and gained 30lbs. I couldn’t stop waiting. My doctor took me off as the weight gain had me in sever depression. She told me she has never heard of people gaining weight. Hopefully my weight I gained goes back. Hoping yours does too. Side effects I just now learned reading others comments.

      I told my husband last night I thought I was dying as I didn’t feel right at all. Some of the side effects hit me the last two days. Know I feel better in the sense I am not dying. As for the side effects they are torture. Dizziness, my body aches, sleeplessness, when I eat I feel like my stomach is going to explode.

  • Christi May 6, 2016, 3:59 pm

    I was moved up to 40mg and when I took it had a reaction. I couldn’t sit still, wanted to pull my hair out had abs still having severe anxiety attacks. My doctor stopped it for 48 hours and then took me back to 20mg and then I’ll go to 10 and stop it. I feel crazy and not myself. Feel for patients who deal with this daily. I had to take 2 Benadryl to counteract the reaction for the next 36 hours every 4 hours. It’s not fun feeling like you’re going crazy.

  • Neceros March 30, 2016, 11:32 pm

    I am supporting someone who has been on Latuda for about 6 months, even though she isn’t bipolar. The doctors continue to amaze me in the depths of their stupidity. She confessed to me she had gone from 60mg to 0mg in over a month or so. She isn’t psychotic, but she’s begun to have psychosis thanks to this and Clonazepam. This drug is very dangerous. If you have an option don’t take Latuda.

  • Gina January 21, 2016, 9:34 pm

    Latuda has worked well for me. Trying to find a way to stay on it has been crazy. My insurance won’t cover it and have received price quotes from the lowest (500.00) for 30 days to 2170.00 for 90 days. Who can afford this drug? It’s a shame because Latuda has had such a positive effect on me, I’m Bipolar. What has really helped me is being on clozapine… I’ve been on it for about 15 years, it has saved my life!

    • Steve January 31, 2016, 5:29 pm

      I was on 20 mg for three months for anxiety, and it helped a lot. Even at this lowest of doses it was pretty potent – sometime it would knock me out within minutes of taking it. However, after the new year, my insurance company dropped it from their formulary. It would cost me over $1,000/month, so I had to part ways with it.

      I titrated down for about a week, by cutting the pills. The withdrawal from this drug is different for me than others. With others, as soon I as started reducing I felt a withdrawal. Not with latuda. I felt almost nothing, which made me eager to taper faster. However, I’ve noticed that the true withdrawal hits when the drug is completely out of your system.

      I’m on day 9 and feel very anxious and have not been sleeping well the past few nights. My stomach/abdomen feels very tense and my skin tingles a little bit. Part of me wonders if I went to fast, but now that it’s done, I don’t want to retreat. If this is what it’s like tapering from a low dose and relatively short duration, I don’t think I’d like to taper after being on it for years.

      • dan April 20, 2016, 10:39 pm

        Check the price. The 80 mg costs the same as the 20 mg ($900 a month). So if you get a mg scale ($25 on amazon) and a good pill cutter you can cut your cost quite a bit.

      • Christi May 6, 2016, 4:02 pm

        I’m scared now with all the withdrawal I’m having it sucks. I feel like a zombie or in someone else’s body. And that’s from the increasing and me reacting badly to it. I’ve only been on it for 1 month but I am done. I’m tapering off it and won’t go back on it. I can’t function.

  • Colleen January 11, 2016, 4:53 pm

    I was on Latuda for two years and found it to be wonderful for my bipolar disorder. It helped with depression and anxiety and suicidal thoughts. I had minimal side effects, I believe only weight gain. Now I’m at the point in my life where I am getting off of it and I am going through withdrawals, headache, blurred vision, and nausea.

    I did experience a clenching of the jaw and pressed tongue while on it. Trouble sleeping and wild crazy dreams. Looking forward to seeing myself off of it, even though it did help me a lot through hard times and would suggest it to friends.

    • Fabulous February 21, 2018, 5:08 pm

      Hi Colleen, I started Latuda 4 months ago and it’s been a godsend — finally got relief from lifelong bipolar depression. I’ve just found out that my insurance won’t pay for it. So I’m going to have to get off of it. That’s why I came to this site.

      Like you, I am in a much better place in my life now, so I’m hoping I’ll be ok. Can you tell me if you were indeed ok without the Latuda? Would appreciate your reply.

  • Austin December 20, 2015, 9:51 pm

    I took Latuda for three weeks. While I was on it, I experienced low sex drive, sleeping problems, and extreme anxiety. The anxiety was so bad, I quit cold turkey, and am now experiencing extreme nausea for weeks with no end in sight. My life has been completely disrupted by this drug.

  • Tina December 14, 2015, 5:19 pm

    My daughter Sami was diagnosed with bi-polar about 2 years ago and put on latuda. They started her on a very low dose of 20mg but increased it very quickly. She was sick to her stomach, lost her appetite, and was sleepy and spaced out that she nearly burned down the house trying to cook when she fell asleep and did not hear the fire alarms going off for over half an hour. She quit taking the drug but later started again because with the bi-polar she could not handle her school work or hold a job.

    She had another couple of times of taking it for a couple of months and then quitting until early this fall. In August of 2015 she began taking and has taken it up until around the first of December where she quit cold turkey. She has been despondent and moody and tired and just not herself the last 10 days and then she had was seems to be a complete break.

    She has been walking around for the last 2 days not knowing who family members were, her eyes look all glassy and she appears to just not be all there, she ended up wandering around barefoot in the snow ranting and laughing and was taken to the emergency room where they had to restrain her and sedate her and they ran a full range of drug and blood tests but could find nothing in her system and nothing physically wrong with her.

    When she awoke from sedation in the hospital yesterday morning she was out of it like she was on drugs and did not recognize people and just seemed to have a general state of confusion, depression, and nervousness. It has been over 48 hours since she first started displaying this crazed behavior and it does not seem to be getting any better. Should she start taking the drug again and will this stop it or should we get something like zoloft to at least lessen the anxiety which is causing her to do crazy things that are endangering her life?

  • Jeff December 12, 2015, 1:55 am

    Thankfully, I am actually sleeping BETTER instead of having insomnia. Dizziness and depression are problems though.

  • Jffbjiy December 5, 2015, 4:15 pm

    Days on this drug are torture. You *never* feel normal…and your waking life turns into waiting until you can just lie down and sleep. Your sexuality disappears…and I’m pretty sure your testosterone takes a huge hit. Discontinued completely due to misdiagnosis, and three months later I’m still off: still can’t feel ‘normal’. Withdrawal from this drug is like living with a perpetual itch in the middle of your back that you can’t scratch: it is, more or less, a constant feeling that you have a craving for something to fix the way you feel…but nothing will fix it.

    It lasts for months. These drugs have wiped a year off of my life. Think very carefully before you go down the medication road. There are hormonal situations (like a combination of high cortisol and testosterone–which, ironically, peak in your twenties) and psychological situations (like isolation–which also peaks in your twenties–with meditation and visualization techniques) that can provoke psychosis in normal individuals with normal levels of white matter and normal dopamine molecules (in other words, avoid meditation to relieve stress, esp. when you are male).

    And if it is a first time episode, you are in your mid twenties and you have just become financially independent, the above is probably you. Think really carefully…were the decisions and thought patterns things you engaged in voluntarily to relieve stress with dopamine releases…or were they things that happened to you while your life was happy and easy? Before you take the plunge into the medication wasteland, verify that you are actually not normal…because these drugs will put at least 15-20 lbs of belly fat on you that may not come off, and they are hell to be on and hell to get off.

  • Kathy November 17, 2015, 6:46 am

    Gosh glad I read everyones experiences, I’ve just been coming of seroquel. Bad stuff, Dr was going to put me on latuda, no way now, sounds too much like seroquel. I’m still trying to survive, headaches. My bones even my teeth ached, diarrhea every 5 min. Shakes, trembles, awake all night… I will sweat and it smells like toxins coming out my pores.

    I am slowly getting better, was on 800 mg per night. Tapered off, crap was really bad, my heart was racing, and thought I was gonna die. Couldn’t leave bathroom to go to Dr. Anyone thinking about seroquel do your homework. I’m glad I did mine and read everyone’s posts. Thanks for maybe saving more grief.

    • Franccesca November 27, 2015, 5:18 pm

      Latuda is very sedating and caused anxiety and restlessness. It’s supposed to be a “wonder drug”, but none if the AP meds are – they dull your brain and make you into couch potatoes! Get out there, stretch, breath more oxygen and move your bodies…I know when you’re depressed, seems impossible to do, but make yourselves do it. Better than have to suffer through all these annoying side effects. Take care and count your blessings. -A mom with a son plagued with this horrific illness of the mind!

  • Le November 1, 2015, 2:21 pm

    It has been 6 weeks since I have been off of latuda. In August I randomly experienced some electric anxiety on the med and started to experience nausea, loss of appetite and mood swings. I was so freaked out by this I decided to taper. That was late August and it has been absolute hell every since. I went on this med for depression but the withdrawal caused the worst depression I have ever experienced in my life.

    The anxiety attacks I would call terror attacks. I went from daydreaming about suicide as relief sometimes to researching suicide methods with seriousness. I keep getting painful depression periods throughout the day. My life was not like this before. I lost 25 pounds in a month from not eating much and was a binge eater before. I still am having weird dreams. I still have anxiety. My perception is still off. The depression has improved but it’s still terrible which tells you about what this drug caused.

    And to be clear, I went without meds and managed my depression for 4 years so I know my depression. This isn’t just a return of symptoms. The depression was like it wiped everything out my brain. I still sobb on and off throughout the day. But this med is messing with my mind. I don’t want to go on another med but I’m not sure im going to make it.

    • DJ December 17, 2016, 8:05 am

      Hope you’re doing ok? You described my interaction with latuda… about the suicidal ideation. I used to think of it once in awhile because I saw and went through so much, now it’s really bad. This is the drug, I’m pretty sure.

  • Ls October 29, 2015, 5:18 pm

    Has anyone experienced an allergic reaction type withdrawal symptom? I was only in Latuda for 3 weeks (20mg, then 40mg then started tapering off back to 20 because I didn’t like the side effects). I have been completely off for four days, and now, I am experiencing itchy, rash like hives on my neck, upper chest and back. I have never had allergies before in my life so I’m not sure if I suddenly developed one to something or if it’s coming off the medicine. So strange!

    • Anonymous August 1, 2016, 6:37 am

      This happened to me when I took Ibuprofen. Reading up on it, any pain reliever seems to have a potentially “serious” interaction with Latuda. Once I stopped the pain meds, the itching went away. Hope this helps.

  • Kelli October 4, 2015, 5:43 pm

    I recently stopped Latuda after a long spell of depression. On a side note, it didn’t feel strong enough so I drank nightly to control my symptoms. Long story short, I got really screwed up and my doc took me off it cold turkey. After 2 days I felt like jumping off the balcony and I couldn’t deal with it. I am back on it now, I have eliminated alcohol from my diet and am doing well so far.

  • Kim September 27, 2015, 9:39 pm

    Bipolar II went from 20mg to 40mg in 40 days. Felt zero improvement in mood. Unbearable side effects: insomnia, restless leg/body, chills/shivers. Felt like I would jump out of my skin. Maddening sleeplessness and body jumpiness. Stopped cold turkey (figured I hadn’t been on it long enough to matter) and am having same side effects a week later. Do not plan on adding another drug to my lithium. This is after 20 years of “try this”, “let’s try this.” etc. Tired of trying.

    • Jim October 29, 2015, 7:56 pm

      I have had a similar experience. I am also Bipolar II and went from 20mg to 40mg in 30 days. I couldn’t bear the side effects (extreme restlessness and insomnia occurred about two hours after taking it; feeling “like I would jump out of my skin” is a good description) so after tapering off to 20mg, I quit cold turkey. I was fine for a few days, but then the side effects started to come back, with the added effects of tremors and a painful headache on the left side of my head about an hour after I get up in the morning each day.

  • Angela September 24, 2015, 6:23 pm

    I have been taking Latuda for about a year. Depression was worse. Have quit cold turkey for my health and have horrible diarrhea. I am scared. I think I was misdiagnosed and have been for years. I was first diagnosed with severe depression now schizoaffective disorder. I am beginning to think that all psychiatrists are quacks and that a pill is not the answer. Any comments would be helpful.

    • DJ December 17, 2016, 8:08 am

      I’m feeling the same way. Behavioral health seems to be a huge scam!

  • lois garrett September 23, 2015, 5:16 pm

    I took Latuda for about 5 weeks. Was up to 60 mgs for less than a week. I don’t know if it helped but I had severe, severe sweating on it. I could hardly dry off from after a shower! I’ve been off it for about 3 weeks and there has been ‘no change’ in the sweating. I can hardly stand it! Does anyone know how long the sweats might last? No other withdrawal symptoms that I know of. I hope there is no permanent damage to my temperature control. Thanks. Lois

  • David September 23, 2015, 2:07 am

    I have been on latuda 80mg for a year. I started to taper down 2 months ago. Today is day 6 I have been off it and 100mg zoloft. I have been struggling with extreme irritability, panic attacks, disillusion, sleep pattern disrupted, energy level low, mood swings and I think that’s it. So far what I’ve been using to help is xanax .5mg to help me go to sleep. I also exercise at a Crossfit gym 4 to 5 days a week.

    The days I don’t exercise are way worse than the ones I do. I also eat a very strict diet of greens, fresh fruits and veggies and meat and nuts. I keep my meals small so I eat often. Eating healthy has a huge impact on my mood. It feels like my food turns into my mood. If I eat crap most likely that’s how I will feel and vice versa. I’m 6 ft tall and weigh 220lbs… I’m drinking about 1 gallon of water a day. Water also has a huge impact on my mood and my ability to feel balanced.

    It almost feels like the water flushes my system and gives me the ability to feel as good as possible. These exercise and diet habits I have been doing for about a year and a half so that helps a lot too. I did almost cuss my boss out today which I’m sure I would’ve lost my job but instead I prayed first and God told me to keep my big lips shut.

    I listened and I thankfully still have a job. Reading the other comments helps me being into perspective the challenges of doing this med. Sobering but I needed to read it to be prepared for what lies ahead. I also have been masturbating once a day since it does an amazing job at centering me and helping me find a balance. I have a good support network of people, psychiatrist, therapist, wife, 4 yr old son and 1 yr old daughter. My best friend is my God Jehovah who I talk to constantly and who helps me make every decision big and small.

    I hope I’ve helped someone because just writing this has really helped me. I hope all of my mental health brothers and sisters find balance and whatever else it is they are searching for. We are the only ones who truly understand each other and I’m glad this site exist so I could share. I will try to keep checking in thru the stages of my withdrawals.

  • Jennifer September 22, 2015, 5:36 pm

    My Dr took me off cold turkey. I have blurry vision, nausea, anxiety, fatigue, body aches, loss of appetite, and restlessness. I don’t think my doctor should have took me off 120mg cold turkey.

  • candi September 4, 2015, 12:50 am

    I took one dose of latuda in the morning and by the end of the night my whole face was swollen. When I woke up the next morning the swelling was so severe I could barely open my eyes let alone keep them open for very long. My lips were tripled in size and I could hardly swallow. My hands was also swollen along with feeling extremely weak and tired. I also had body aches and a headache that kept persisting. I called my pharmacist and she had an urgency in her voice to take benadryl and put an urgent call into my Dr. It’s been three days now and I’m still swollen in my face. So until latuda is completely out of my system I have to take benadryl. I don’t suggest this drug to anyone!!!

  • adam August 27, 2015, 8:43 pm

    I been taking Latuda for about 16 days, and after realizing that I was miss diagnosed, and that the effects of the Latuda was more harmful then helpful, I decided to stop taking it. I was on 20mg at nighttime, and I just got past the mark where the drug has left my system (36 hours). I been experiencing what I believe or withdrawals, but not sure.

    I am experiencing nausea, restlessness, and my brain feels tingly or just light headed. I have severe fatigue and soreness all over my body, but especially the legs. My doctor is unavailable (big surprise) and I can not break a 20 into a 10, so decreasing dosage isn’t possible. I imagine the withdrawals will get worse before getting better. My main concern is having seizures from it.

    The only other drug I am taking is Clonazepam at the moment and 10 mg of Lamotrigine, which I am also trying to come off of as well. What should I do? Should I go to the emergency room or just wait it out? Any input would be helpful.

    • Vic January 8, 2017, 10:36 pm

      I break mine in half… I have 40’s. My doctor also said I could crush it and swallow it. Helps with nausea.

  • Sharon August 13, 2015, 2:03 am

    I’ve been tapering off of Latuda for 4 weeks from 40mg, to 30mg, to 20mg and on day 11 of the 20’s I started withdrawal symptoms. I am experiencing nausea, trouble sleeping, spaciness, sweating, grumpiness, mood swings, dizziness at times, and memory problems. I don’t understand why all of a sudden I started experiencing this problem. I have a call into the Psych’s office but they haven’t gotten back to me, my Psych is on vacation this week unfortunately. This is miserable. So I have to decide on my own whether to continue at 20, go to 10 or what to do! It sucks.

  • Gina July 23, 2015, 7:41 pm

    I have been taking 60mg of latuda for about three years. I recently tapered down and eventually got off of it within a month timespan. The withdrawal symptom that I’m feeling the most is nausea. I constantly feel nauseous. Has anyone else gone through this and if so how long did it last after stopping the medication?

  • Dosedup July 5, 2015, 7:52 pm

    I also have been taking latuda at 160 mg for a long time and am experiencing weight gain, memory loss, and general “masked face” that is described in medical literature. I want to get off the medication, but I worry from these other posts that I will never be the same again – that I will experience permanent anxiousness, depression, and memory problems even more than I am facing right now – can anyone offer any advice?

    I also feel like maybe I am psyching myself out and that I might be better off with the medication and this is a desire to get off medication altogether, which might not be a productive goal. I would love to speak with anyone about this – I feel alone in that the medical literature is so conflicting with the comments I am reading. I want to return to my normal, bright self before I was diagnosed with schizophrenia!

    • Wes September 11, 2015, 12:20 pm

      I was at 20 mg Latuda nightly for months when I tried getting off. I went to 10 mg for four weeks. This worked pretty well at first. None of the anger, anxiety, muscle pains occurred. I think people should come off of it slower like I did. I was taking it for preventing suicidality. After five and a half weeks off it, I was so suicidal I had to go back on it. I use 10 mg a night and it works great for me at this minimal level. Everyone withdrawing should take it very slow.

  • Sheri May 31, 2015, 8:00 pm

    Long story short, I was put on Latuda last July, had really bad restlessness and anxiety, so they put me on cogentin for side effects. I gained over 50lbs since then. Anyway, it was discovered that my actual diagnosis is actually Complex PTSD as opposed to bipolar, so a few months ago I started getting tapered, gladly, off meds, Latuda being one, down a dosage every two weeks. I was on 100mg Latuda, and the tapering process wasn’t too bad until I got to 40mg. I was there for two weeks, went down to 20mg for almost two weeks, and now I’m off since this past Thursday. It is now Sunday, and I feel SO sick! Mentally I’m OK, but physically I feel horrible! I have severe body/joint and muscle aches, blurred vision, hypersensitivity to sound and light, fatigue, pressure in my head and face, chills, nausea, etc. I hope this doesn’t last too long, I feel miserable!

    • Briana November 14, 2015, 5:07 am

      I was misdiagnosed too. The antipsychotics only made me flat with little emotion but fear. Just took myself off the latuda due to health problems, plus realize the diagnoses of 1st schizoaffective and later bipolar were wrong. I too have complex PTSD. I have dissociative disorder as well…I zone out. I’ve had a week of amnesia from it 3 times since 2015. Smaller bouts of amnesia last hour plus, I’d like to talk with someone else about it.

      I’m currently seeking a therapist but wont start until I move beginning of January. If you’re interested in sharing more or just talking with someone that probably relates, please email me breebear[AT]outlook.com. The antipsychotics took me from an athletic 130 lbs to 285 lbs diagnosed morbidly obese. Other health problems as a result. I believe that a lot of mental illness could be worked out in long term therapy, with only temporary meds given if at all.

      Exercise and a high veggie/protein/healthy fat diet is working. Past few weeks I have been eating anything due to withdrawal symptoms…so need to get back on track. Very tired, muscle pain and spasm, anxiety, feeling disconnected and like something bad is about to happen. I’m curious if withdrawals could cause a heart attack. Felt like I had one 2 weeks ago…started with pounding heart and palpitations. I didn’t call 911. I’ve been 3 times before and it was anxiety. EMT guy said for me to stop wasting their time.

  • Yesi May 20, 2015, 10:16 pm

    This medication has caused me alot of problems coming out of it, little did I know that all psychotic medication causes diabetes. However, while on it I started having panic attacks and sleepless nights waking up with anxiety. I no longer take the medication and almost 4 weeks after still at night can’t have a full night sleep because I wake up with panic and my heart beats fast. How much longer do I have to wait for everything to get back to normal?

  • Jody Rodman May 10, 2015, 8:03 pm

    I went off 80 mg of latuda cold turkey about a month and a half ago. It gave me severe anxiety and the shakes. I was taking it for 2 years and after I stopped, I realized I hadn’t laughed since I started taking it. Although I am not flat anymore and my real personality is coming back, I have still not been able to laugh. The anxiety is a bit less, but the shakiness and uneasiness is worse. I also feel restless all the time. Does anybody else out there have any of these symptoms and if so, how long does it take before you felt better?

    • John May 21, 2015, 10:47 pm

      I was on latuda 60mg for almost three years, and quit it cold turkey. After few days stop taking it, I feeling super super anxious!! Kind of like social phobia or anxiety!! Right now it’s been almost 4 months, and still feeling anxious almost most the time!! And this is the only withdrawal symptom I have! And I really wanna know how long it going to last!?

  • Emi April 29, 2015, 11:51 pm

    I am coming off of 160mgs of Latuda cold-turkey after 4 months of upping the dosage. I was told it was safe to do so. Further independent research says standard procedure is to wean by 20mgs every two weeks. I’m one week in and I’m having confusion, rage, negative impulses, headaches, and for the past two days very intense pain in any muscle I use in any way, like for typing or nodding my head. No stomach or sleep problems. Very poor memory. Two days ago I didn’t recognize my mom’s face, but I recognized her voice.

    I live with her, so I see her every day. I’m not really experiencing mood swings, and my psychosis has gone way down from when I was on the Latuda. The last increase in dose led to three weeks of a medium-strength mushroom trip, which, to explain, meant that colors changed at random, depth perception changes (for instance, if you’re looking down a hallway, the end of it may stretch away from you a great distance and then rush back toward you), light gets much brighter and then much more dim, and the size and shape of objects changes the longer you look at them.

    The only difference was that there is no increase in dopamine, like on mushrooms, so it’s not “magical”, it is highly disruptive to normal functioning. I’ve done a lot of psychedelics (I don’t anymore), and I have a lot of hallucinations and delusions, so it wasn’t scary unless I was having a paranoid delusion with it, but as it happened I was having them at least twice a day during this time.

    Also, on the Latuda I was having intense chest pain that eventually sent me to the hospital last Tuesday, at which point I was instructed to stop taking it. I also had shooting pains in other, randomized locations on my body on the Latuda. Even though I’m miserable now, I would rather go through intense discomfort now (it should get better once I’m placed on another antipsychotic, my appointment is on Monday) than spend eight weeks detoxing. Plus, it was doctor’s orders.

  • Joy April 25, 2015, 5:17 pm

    I have been on antidepressants since age 9 (over 20 years), and I am used to withdrawal. The last time they decreased my Latuda was from 120 mg to 40mg in the hospital in preparation for ECTs. Now, I am going from 80mg to 60mg, and am experiencing withdrawal again. One nurse said to go to the hospital, but my GP and pharmacists think I am going through normal withdrawal. I am dizzy, confused, tired, have a head ache, and lack motor skills. I do not have an upset stomach yet, but am prepared. I can’t drive for 2 days.

  • Elizabeth April 24, 2015, 2:25 pm

    I was on 40 MG of Latuda for 2 months until I increased to 80 MG with the aid of Gabapentin 100 MG 3 times a day and neither of anything for me. I felt exactly the same, if anything worse because I became delusional. I stopped taking it without my doctor’s permission and I have felt no withdrawal symptoms at all.

  • Cliff April 20, 2015, 9:05 pm

    I have been on a number of medications over the last year and a half, with zero affect. The doctors have labeled me as “med resistant” because no matter which medication they put me on, there doesn’t seem to be any affect, aside from side affects that is. I started taking Latuda at 20mg per day, then increased to 40mg. The doctor stated that it should be taken around bedtime, but, some people prefer to take it in the mornings, given the issues I have during the day, I equated having a calmer day to leading into a calmer night… I was wrong.

    About 3 hours after taking this medication it made me feel a way that I really can’t describe… antsy,anxious, rage-filled, severely restless, so I had to switch to taking it at night. I had to time this just right so that I wouldn’t be awake when the effects hit. I stopped taking this medication this past week, I wasn’t experiencing any positive affects from it, and and so no reason to take something that only gave me a negative. I didn’t suffer from any withdrawals, but, I think that would probably attributed to being med resistant.

  • Sarah April 20, 2015, 6:32 pm

    My experience with Latuda has been a living hell. Some of the darkest most terrifying thoughts that have ever been in my head and the closest I’ve ever come to actually killing myself. I don’t know who I am anymore. Will I ever get my life back? I’ve been off it about a week and this is the most depressed I’ve ever been during 20 years of depression. Truly evil side effects.

  • Jamie April 18, 2015, 3:25 am

    Thank you all for your posts, you have helped me feel a little better while being so sick. I took Latuda for over 4 years and it helped me a lot but I had to take Promethazine with it cause I got severe nausea from the Latuda. I just decided I wanted to be on a cheaper drug and my doctor said I could quit cold turkey since I was on lowest dose. I’ve been physically ill, got horrible headaches and anxiety so bad I ended up in medi-center and given Valium. I would like somebody to post that this stuff will end…eventually. I’m kinda scared I’ll be stuck like this.

  • April April 8, 2015, 2:42 am

    I was on 20 mg of Latuda for one week, then it was increased to 40mg. I increased it to 40mg on a Friday morning, within two hours I was in the ER with horrible effects. I didn’t take it on Saturday, I appeared to be fine. Sunday morning I took it the same time I did on Friday and was in the hospital again within two hours. The symptoms I was feeling was hot flashes, dizziness, skin flushing, muscle cramping throughout my body beyond belief. I could hardly walk. This medication was stopped by my doctor cold turkey because of the adverse reactions. I feel like total crap, I am on day 2 of not taking this. I hope the withdrawals clear quick!

  • rklewis2 March 24, 2015, 8:06 pm

    My best friend was on this medication for a month. Then the Dr stopped it upon discharge from the hospital. Within 12 hours of stopping this and starting another like med she lost her balance and fell backwards down a heavily carpeted stairway breaking her neck and dying. Autopsy confirmed she was in multi system shut down from Latuda! Do not ignore changing symptoms. Always get to a Dr or ER and get assistance for your loved ones when any mental or physical changes in Gait or Balance are noted!!

    • Jess Smith July 2, 2015, 1:40 pm

      Psychs need to be held accountable for causing these tragedies with their carelessness. Stories like this are heartbreakingly, infuriatingly common. I’m so sorry for your loss.

  • MB March 7, 2015, 6:05 pm

    I’ve been on Latuda for almost 2 years. I had a great experience with it to be honest it helped me through a very hard time in my life with suicidal tendencies. I will say one thing though: despite what it claims about enhancing memory I actually found the opposite to be true. Before I had perfect recall, which was one of my problems because some things shouldn’t be remembered. Once on latuda my memory changed drastically which I never complained about. I’m now going off latuda and have experienced almost zero withdrawal symptoms but its been about 2 weeks and my memory has not yet regained its former state. I’ll give it more time since I was on it awhile.

    • Tali December 23, 2015, 3:35 pm

      Like you, I was put on Latuda for severe depression. It was great! I wasn’t able to tolerate other depression drugs so this was a last resort. After 2 days I felt much better, I also stopped biting my fingers from anxiety. And when I took it with dinner, I had some of the best sleep and dreams of my life. I’ve been on it 3 months.

      And went on vacay and forgot my meds and have gone off cold turkey. The only side effect I’m feeling is a little weepiness and a little nausea, but other than that I’m okay. The depression hasn’t come back so far. So I’m grateful. This drug has been a lifesaver for me but now that I’m doing good without it, I think I’ll stay off it.

  • maureen March 5, 2015, 1:05 am

    I’m bipolar 1 and have PTSD. Was on Latuda 60mg for over one month and gained almost 18 pounds. My blood pressure skyrocketed et al. I’m currently being weaned from Latuda and it is a living hell. I’m being tirated from 40mg right now to 20mg next week. For the most part I am having severe depression with significant suicidal thoughts. Anger and rage problems as well as agitation. I cannot get a decent amount of sleep at night and awaken exhausted from nightmares.

    I pray to whomever is up there that this garbage ends soon. ‘Plain old Bipolar mixed with PTSD” is easier to predict and deal with than the withdrawal effects of this crap. I would never recommend Latuda to anyone. Anyone have any idea how long I will be like this? I was only on Latuda for one month. Thanks everyone for sharing, I don’t feel as alone now and I hope that we can all make it through to the other side of this.

    • Cianna Brueggemann November 24, 2016, 6:41 am

      Have these symptoms subsided ?

  • John February 27, 2015, 3:09 am

    Was on 60mg for two and half years and quit cold turkey. So far its been about one month from my last dose. I’m feeling very very anxious, and wake up depressed ( 1-2 hrs), and also dizzy.

  • Christy February 20, 2015, 2:26 am

    Latuda almost killed me. I began taking it with Trileptal. I was on both for almost 4 weeks. The Latuda attacked my bone marrow (there is correct terminology for this but I like to keep it simple and degenerate) It screwed with specific types of blood cells. I feel like the Trileptal is what made the roof of my mouth swell and hurt so much. Periodontitis erupted in my mouth.

    I couldn’t wake up in the morning. I bled 3 times the normal amount of my usual menstrual cycle within the 4 weeks. I was seeing a clinician who disregarded most of my symptoms blaming them on other things. I’ve done a lot of research on Latuda, everything I experienced is within the information available, even if it is rare/adverse/hypersensitive side effects. What I haven’t been able to determine is if this happened because I already had something cancerous going and simply didn’t know it.

    I had my blood work done yesterday at the ER and it came back fine but I feel like complete crap and am going through different horrible things as each week passes. I have been taking cymbalta for the past 2 weeks because I abruptly discontinued both of the evil meds, hauled off to an urgent care place begging for help with anxiety and depression. I feel awful physically. This is horrible. I have tinnitus, trembling, joint/bone pain, muscle spasms, fatigue and weakness.

    The ER said all of it is because of the Latuda and Trileptal. I could only sleep about 2 hours at a time since abrupt disc before waking up covered in sweat from my chin to my thighs. The cymbalta seemed to put a dent in the night sweats. I can’t wait to feel better again. I will never take bipolar meds again. I pray to God this didn’t set off some kind of cancer in me.

  • sandra February 19, 2015, 1:29 am

    Worst feeling I have ever experienced. Taking 80mg I stopped cold turkey. I am feeling: dizzy, nausea, double vision, feeling off my body, no energy, migraine, unable to sleep, very very tired, feel very sad, very very sad.

  • Anthony February 8, 2015, 3:27 am

    I was on 40 for a few days and stopped the. Did 60 for a few days then stopped then I did 80. For like four or 5 days and got drunk. That did a huge number on my body in where I wasn’t sleeping so took 40 again one night and then 80 the second night. This has caused crazy thoughts and couldn’t feel any pleasure BC my mind was so whacked.

    Started sleeping better but not totally there yet. Still have paranoia and sweating and restlessness. I wasn’t on latuda for long, but mixing it with alcohol after jumping to 80mg in less than a week really screwed with my energy levels in a huge way. Looking forward to returning to normal just don’t know when that will be. God is healing me and my mind WILL be well in jesus name.

  • C-DR February 7, 2015, 5:26 am

    I have been on Latuda 60mg as a treatment for psychotic symptoms for about 2 years, and I went off cold turkey and have experienced 0 withdrawal symptoms. It’s been about a week.

  • tonya February 1, 2015, 5:14 pm

    I have only been off my 20mg for 2 days due to insurance issues and I have the worst migraine in my life! The pressure is horrible! And sweating and nausea. But the headache is worse than any. Please if you can taper off this thing do it because this is horrible!

  • P B January 19, 2015, 5:24 pm

    On latuda 3 months. Started at 20mg told to stop abruptly at 80mg. Have been experiencing withdrawal symptoms for 2 months now. Suicidal for the first 4 wks. My psych did not see the need for weaning. Bad decision.

  • Marsh January 17, 2015, 11:18 pm

    I started taking 80 mg of Latuda in mid-October 2014 and a month later I started to feel muscle aches, bone aches, joint aches, tingling. I quit cold turkey on January 2, 2015. My doc gave me new medication. Right now its 15 days after I quit cold turkey and the muscle, bone pains are almost gone. I feel better. I did feel confused during my withdrawal. My pains are minor and I hope the pains will go away this week.

  • Jolene January 10, 2015, 1:43 am

    I was only on for 4 to 6 weeks. Went to the ER with chest pain. Dr said it was the latuda 80 mg. The withdrawal is horrendous: Shakes, chills, high pulse, borderline BP, nausea, diarrhea, no appetite, racing heart, foggy, exhausted, sleepless, dizzy, migraines, muscle pain and fever. I never experienced anything like this. Fortunately my heart is healthy. I hope it stops soon. Called my dr and she’s having me taper over 4 days. I just wonder if that’s enough.

    • Anna November 2, 2015, 11:48 pm

      I took latuda for 5 weeks. I stopped taking it because around week three I started getting agitated really easily. My doc is on vacation and I was taking 20 mg. But I feel really weird right now. My vision feels weird and I’ve had a nervous feeling in my stomach that won’t go away. I can sleep, but that’s mainly because I take sleeping pills. I get random feelings of wanting to throw up. I honestly didn’t think I’d get withdrawals since I’ve only been on it for 5 weeks at a low dose, but I sure don’t feel normal. I feel a deep sense of unease in my own skin. I really hate this.

  • Sam January 4, 2015, 2:22 pm

    I started taking Latuda at 20mg at bedtime once a day for Bipolar I in August 2013. I was increased all the way up to 80mg at bedtime once a day by December 2014. At first I liked being on it but as the dosages increased I noticed I would get nausea shortly after taking it and headaches. My psychiatrist told me to eat before taking it to reduce the nausea. After being on it for awhile family members told me that I was irritable a lot.

    I have since decided to cold turkey quit the medication because I am fed up with the side effects and my family telling me I am irritable all the time. The side effects I am experiencing during withdrawal this far during cold turkey quitting and I am one week into it have been:

    – suicidal thoughts
    – poor concentration
    – feeling detached
    – poor sex drive
    – depressive mood
    – lack of motivation
    – feeling spaced out

    That’s all I can think of right now. But it is not as easy to get off of as other meds I have been on. This drug is not as great as they make it seem.

    • Birch May 17, 2015, 7:42 pm

      Wow. My boyfriend is going through this right now. We both are extremely angry that his Dr prescribed 80mg for insomnia. My BF is not bipolar and doesn’t have schizophrenia. This is a powerful drug that had actually put out his fire. We finally had a chat about his “checking out” of life and it’s the Latuda. He basically has every single side effect.

  • Ann December 27, 2014, 11:42 am

    I have been waking up energized since I started taking Latuda. I am able to sleep at least 6 hours straight then can’t go back to sleep. The suicidal thoughts have stopped as well and I was able go get through Christmas without the extra drama. However, I just ran out and currently have no way of getting more. I’m waiting for my insurance to go through. But long story short, after stopping cold turkey I am still waking up energized but now an hour or two earlier and can’t go back to sleep…

  • Tiffany December 17, 2014, 4:54 pm

    I switched to a new psychiatrist last week, and he completely changed my meds around. I was taking 15mg Prozac, 900mg lithium, and 80mg Latuda. Well, this new doc took me off of Latuda cold turkey, is tapering my lithium down each week, and increased my Prozac to 40mg. This started on 12/11 and on 12/15 I started having really bad withdrawals and I cannot figure out why or what it is from, but I’m assuming it’s the discontinuation of the Latuda. I’ve been having tremors, mood swings, anger, irritability, blurry vision, and I feel like I’m out of my mind….like I’m sitting here but my brain is on the other side of the room floating. I’ve sent a message to my Dr. to see what I am supposed to do because all of these withdrawals are horrible!

    • Dj February 29, 2016, 4:44 am

      Find a different doctor. None of these meds should be stopped cold turkey. If you are bipolar, an antidepressant will swing you over to mania and possible psychosis.

  • Carina December 15, 2014, 8:03 pm

    I’ve been on Latuda for over 2 years. My Dr put me all the way up to 160mg. I started experiencing muscling stiffness and and horrible muscle spasms. As time went on I began experiencing more side effects such as exhaustion, deeper depression however no manic spells at all. Which with a 3 and 4 year old I could’ve kinda used the energy. My hair began falling out in clumps, lock jaw, chewing and sucking on my tongue and worst of all I started to lactate.

    Yes from my breast, how embarrassing during an intimate moment. This medicine wasn’t helping me I felt worse about myself gained over 75 pounds. I didn’t know what to do. Now I’m dosing down. It feels horrible. Restlessness, severe increased anxiety, body aches, head aches double vision, fainting. I’m just praying that this will all dissipate and I’ll start to have clarity again. Hope this helps anyone.

    • Jeri April 21, 2016, 4:02 am

      I feel for you. I hope you are doing better now. They put my son on 160mg and ruined our life. It was so hard to come off this drug. Everyday was a crisis for 2 years on this drug and coming off of it. 160 mg would only be prescribed by a quack!

      • Shannon August 28, 2016, 5:56 pm

        I took Latuda 80mg down to 40mg, then down to 10mg. Decreased dosage because I felt extremely foggy and lethargic. Sometimes it felt like my brain was on fire. I’m guessing it was too much serotonin levels for me to handle. Turns out I switched MD’s and he took me off it. Just taking Lamictal 150mg every day.

        I tapered by taking one 20mg tab and cutting it into 4 pieces and then 8. Taking crumb sized pieces. When I got down to my last pill I took one piece every other day, till gone. I have increased levels of energy and I don’t get mood swings anymore at all. I felt like the med was making me have random bursts of uncontrollable anger. I feel great now, just dealing with migraines that won’t quit.

        It’s been 2 weeks since I’ve been off and I’ve had a migraine almost every day. So bad I was thinking of going back on it. I’m assuming this won’t last long. Also I’ve been having periods of confusion, not sure it’s associated with the migraine considering it’s a symptom of migraines, I’m hoping these migraines will stop harassing me. Leaving work early and missing days due to a migraine is really getting me down.

        I’m completely fine for the most part but do have some anxiety/insomnia (Doctor have me on trazodone and klonopin). Getting off such an intense/strong drug is so hard. Glad to hear that some people are having the same symptoms. Hang in there I say… thanks for sharing your stories.

    • Cianna Brueggemann November 24, 2016, 6:38 am

      Did that ever go away? I’m over a month off and still have the restlessness…

    • Linda Burkett November 28, 2016, 7:06 pm

      I hope you feel better soon. I am going to start tapering off Latuda and I am scared that I am going to feel like sh-t.

    • Jackie January 24, 2018, 1:27 am

      How are things going now? I’m a week and a half off and feel awful.

  • Sarah December 3, 2014, 4:59 pm

    I was on 2 mg of Latuda for one week and then my doctor upped it to 40 then eventually 60 mg a day over the course of 3 weeks. When my dose increased, I felt extreme panic, extremely restless movements, feeling as if the walls were closing in around me. I felt hopeless and paced around my home for 4 hours praying for the dreadful symptoms to subside. I even contemplated calling 911. Luckily my boyfriend was able to come home from work and console me until I passed out from literal exhaustion.

    My doctor told me to immediately stop taking it and prescribed me Xanax to handle any withdrawal symptoms if I were to have any. I did have severe headaches, insomnia, lack of normal appetite. About one week later, I had my follow up appointment and my Dr. prescribed me Depakote. My bipolar manic and depressive symptoms are all but gone and I feel hopeful that I am on the right track. So don’t give up hope, there will always be the medicine for you.

  • Nic November 19, 2014, 11:50 pm

    I have insurance through my husband overseas so I have to pay in advance (get reimbursed 3 months later) and was horrified to discover the price is $854 at CVS for a 30-day supply (dosage 40 mg). I pay 20% of medicaments so I am just shocked at the price. The drug is too new for them to experiment on me and for me to get locked in at that price. If something should happen to my insurance and to be on a drug that costs that much… I may be insane but I’m not crazy. I was given 4 one-week packs so hopefully quitting cold turkey will not be too bad. I experienced a lot of dizziness and brain zaps getting off Prozac and Neurontin 13 years ago when I was last on medication. Good luck to all.

    • Doug November 7, 2015, 9:07 pm

      First I thought there were substantial discount coupons available for most people. Don’t ask me how or what, I am in Canada. One months supply is $145. I get 120 mg dosage and split it 4 ways. Doesn’t matter what the dose is the price is the same. Pretty screwy but once you figure it if your doc will cooperate it gets fairly reasonable.

    • Jen January 19, 2016, 1:23 am

      I had been on it for almost a year. I had met my deductable last year, and now that it’s the new year I found that my 30 day supply was around $900. I couldn’t afford it, so I quit cold a few weeks ago. Today has been the 1st really low day I have had, feel out of my body and just not myself. I have been crying for no reason and just lethargic all day. Not sure if this is withdraw or my mind’s “normal” state.

    • Amalia Langford April 15, 2016, 2:15 pm

      Look into Latuda’s $15 copay card!! Huge savings!! I used it at CVS!! Good luck!

  • elsa November 18, 2014, 3:02 am

    I for one am having serious withdrawal symptoms. Mood swings, lack of energy, suicidal thoughts. I even wrote down my possible suicide note for my loved ones and friends to cope with. Every day is a struggle and I find myself wondering if today is the day that I will date my goodbye note. I already called my therapist, hopefully the pharmacy will have something for me tomorrow. Recommendation, withdraw slowly not cold turkey.

    • Michaela November 30, 2014, 7:38 am

      My psychiatrist switched me from Latuda to Geodon while I was in the hospital about a week and a half ago. I really wish he would stop taking me off medications cold turkey because I’ve always had to deal with substantial withdrawal symptoms. Anyway, since he took me off Latuda I’ve been extremely dizzy, I’ve been depressed, anxious, suicidal, and my thoughts have been increasingly difficult to understand. It’s hard to function because I have a heck of a time following conversations, putting an intelligent thought together, and I’m so easily distracted – I hope that’s the withdrawal, anyway, otherwise I’m in trouble.

  • Stephanie November 16, 2014, 6:03 pm

    I had a very rapid w/d from latuda and at first I had flu like symptoms, sweating, nausea, insomnia and an internal fear inside and severe depression. It’s been 9 weeks off and I have windows of feeling ok than the internal fear comes back and I’m paralyzed. It also gave me severe anxiety that I never had before. Could it be protracted withdrawal. It should of been a 3 month taper and was done in 8 days.

    • John March 14, 2015, 5:30 pm

      I’m 6 weeks off now, was on 60mg for almost 3 years. Since I stopped, I’m feeling super super anxious too, it’s kind of like social anxiety, which I never had before. I want to know are you feeling the same, or anyone?

      • Carale March 29, 2016, 2:45 am

        I went off rapidly as well and yes super social anxiety. I don’t leave the house, see no friends and barely answer the phone. Horrible!

      • Phil August 17, 2016, 8:22 pm

        I’ve been on it for three years at 120mg, I dropped to 60mg about three months ago and same thing. Lots and lots of anxiety. Kind of like a prolonged mild panic attack.

      • Jackie January 24, 2018, 1:12 am

        I was on 120 mg of Latuda as well as 400mg of Lamictal. I’ve tapered off both and it’s been about a week and a half. I feel terrible. I had to call in sick to work today. I gained about 80 lbs and am happy to see the weight go down but this is the only good thing. Has anyone tried cannabis to help with the anxiety?

    • Michele December 1, 2016, 11:16 pm

      I have been on this medication for over a year and have found my anxiety has steadily increased over time. It’s to the point now where I’m agoraphobic and cannot go anywhere or do anything without being anxious. I have found out it may be due to this med. I am currently weaning down my dose to find out if this is truly the cause. Coming off of 40 mg down to 20, then off completely… you are not the only one who has been anxious on it!

      • Thomasina January 27, 2017, 3:37 am

        This is exactly how I am feeling!! I can barely do anything and when I do I’m a nervous wreck the whole time. I’ve been on it for years and getting off of it. Was on 40 mg now tapering off to 20 mg for a week then done. I’m so nervous about the withdrawal symptoms!! I hope it makes my horrible anxiety go away!!

  • Anyony November 3, 2014, 4:08 am

    “The worst side effect I experienced and still am is the act that my tongue is pressed up against the roof of my mouth continuously”

    I have that exact side effect if I take it in the day. People who haven’t experienced it wouldn’t believe how annoying and distracting it is.

    @Nicole: did that happen if you took it before bed? As I said, I’d never intentionally take it during the day, but the restlessness was never a problem if I took it less than an hour before bed. Of course, that means you need to eat a large snack right before bed, which I really don’t need.

    I’m just off it for a few days because of a prescription mixup, and the lightheadedness from withdrawal is pretty bad. Feels like a combination of a hangover and the flu. Hope I don’t go through the initial screwed up sleep phase again when I start up next week.

    • Brandon November 4, 2014, 8:10 am

      Look up tardive dyskinesia… Tell your doctor if your experiencing any symptoms involving tongue neck or any involuntary muscl 3 problems. THEY CAN BE PERMANENT. Latuda works for me, however, when I forget two days in a row, it’s the worst withdrawals you could ever imagine. Worse than opiates or benzos. The thought of something happening and running out scares me so much I’m weening off rather than reaping the benefits.

      • Gerry June 15, 2015, 7:29 pm

        You are the first person on here to describe what the withdrawal feeling is for latuda after 2 days. If I forget to take after a couple of days I start to feel like a zombie and my sleep pattern gets all screwed up. I have been on it for about 6 months. It is amazing how after remembering to go back on a regular schedule again how quickly it works. I guess it is a lot stronger drug than I thought. I take it along with Celexa. I had a spinal cord injury 12 years ago and because of the nerve damage if I don’t take celexa everyday I end up all I want to do is cry. Thanks for your comment it has helped me.

      • KM March 16, 2016, 11:19 am

        I have tried twice to get off this stuff. I currently take 40 mg. While on it I do great and feel great, but I hate meds. So I tried tapering. I take it at night-by 10 am the next morning I am ready to jump off a bridge and so restless I can’t stand it. My old shrink just said to stop cold turkey but she was a flake.

        I worry about the long term effects of this, but I’ve never felt this good my whole life, so I guess I will take meds for the rest of my life. I’m not going to try to stop it anymore. I can tell my brain is altered, but it beats the alternative. Otherwise, I love this stuff. My insurance doesn’t cover it, so Im worried about the day the samples will no longer be available.

        • Teri B Clark June 16, 2016, 6:45 pm

          You can buy it in Canada for much cheaper. My husband bought the 80mg and cut it in half. So, we were getting a two months supply for $175. Much better than US prices.

  • Nicole October 31, 2014, 6:41 pm

    I had a HORRIBLE experience with Latuda, which is weird because my psychiatrist said most people really do well on Latuda. It gave me a feeling of EXTREME restlessness that I could not bear. I couldn’t even drive on it because it made me so restless I just wanted to drive off the rode or crash my car. I was on 20-40 mg for two weeks and I just could not stand this feeling. It also gave me pretty bad nausea… Withdrawing from it now and still experiencing the nausea and some restlessness. It was like a devil drug for me and it scared me away from all antipsychotics. The side effects are so hard to deal with and it sucks because I really need to take them.

    • Jason March 3, 2016, 10:30 pm

      Yes me too I felt like I wanted to jump out of my skeleton. Be careful with this drug!!!

    • Heidi May 29, 2016, 1:20 am

      I’ve been taking Latuda for about 3 weeks now. It’s in addition to Wellbutrin 450mg and Pristiq 50mg… added to help with suicidal ideation etc… I’ve had success with Abilify and Seroquel, but didn’t like the weight gain… The Dr started me slowly, cutting the pill in half for 2 days then another 2 days on next dose, etc… “Because she could,” she said.

      No problems except the slight nausea… But definitely taking it with food helps!!! When I got up to 40mg, I believe, I experienced the symptom you’re describing… Maybe the second day on that dose. It’s called akathisia, which is common with antipsychotics (I guess?) and the Dr had warned me about this. She added Cogentin .5 mg (tablet cut in half) to take with the Latuda…

      Saying that I could go w/ the the full 1mg, if needed. After about 2 weeks, the .5mg Cogentin was causing slightly-blurry near vision and mild light sensitivity… So I stopped it one night and (surprisingly) I found I no longer needed it, my body had adjusted to the Latuda. Just thought I’d share that you can get over this initial “tense/crawling” sensation if you stick with it. I’m now taking 80mg without Cogentin…

      And I’ll see how this works for me. My thoughts do seem clearer, but it’s definitely making my mood kind of indifferent, so I’m interested how this is going to go. FYI, I was looking up withdrawal symptoms because this drug is a huge pain in the ass to get and I thought I’d have to go a few days without it until my Rx arrived after the 3-day weekend.

      Luckily I was able to get *4* tablets from a pharmacy an hour away… LOL! 😳 For serious. This stuff is expensive! I hope it works!!

    • Molly June 24, 2016, 7:50 pm

      I also had EXTREME restlessness. My legs, my body. Which really sucked because I considered this drug my miracle drug. I got rid of my suicidal thoughts my depression that came alone with my bipolar. But sadly I had to quit. I did this and right now I have extremely dry mouth, vertigo, nausea, vomiting, still restless but mainly my legs now and not as bad.

      I’ve also had weakness after stopping. I’m really disappointed that I had to quit because of the insomnia and extreme restlessness. I really liked myself on this drug. :-(

      • Brenda August 16, 2016, 9:15 pm

        @ Molly… What was your dosage for Latuda?… I am on 40 mg and considering tapering off… I’m currently on another medication for the insomnia :/

  • Debbi Ross October 22, 2014, 6:34 pm

    I’ve been taking Latuda around 5-6 weeks and found it helpful in eliminating suicidal thoughts. All of a sudden (yesterday and today) I am seeing double and I am not able to walk a straight line. I am all over the place. What happened? I am unable to drive due to my double vision. I am waiting to talk to my doctor, but know I must discontinue this drug. Apparently it often is a bad combination with Lithium. Bummer.

    • Isabella Macher October 30, 2014, 9:59 pm

      Debbie, I’ve been on Latuda for about 8 weeks and just like you, I’ve experienced some relief from the horrible and persistent suicidal thoughts. I had bad blurred vision from the beginning but I was hoping it will go away. My Dr. lowered the doses to 20, but the blurred vision didn’t go away. Today she told me to stop it an she prescribed Lithium instead. I will taper off although she said to just stop it! I hope it goes well for you.

  • flora October 22, 2014, 1:53 am

    I was taking latuda for 2 years and experienced severe side effects such as impaired judgment, confusion, nausea, tremors, pulling my tongue back just to name a few. I’ve been off of latuda for about a month now and feel my mind begin to clear up. The withdrawal I’ve experienced from it has been sweating, sleeplessness. I don’t want to go back to this drug nor any other antipsychotic medicine I’d prefer to hear voices instead.

    • AG December 2, 2015, 7:39 am

      I have the same experience with my tongue, I was off this medicine more than a week ago and I still can’t properly chew food. I hope it will go away and is not permanent. Do you think it can stay permanent or I should wait?

      • Dj February 29, 2016, 4:37 am

        I hope this issue went away for you. It can become permanent. Talk to your psychiatrist – benzos can help.

      • Carale March 29, 2016, 2:41 am

        I’ve been off for 5 months now and my tongue still won’t stop!

        • Charlene September 6, 2016, 2:44 am

          There is a medication called cogentin that helps with those side effects. Ask your Dr about it. I’ve taken it the whole time I’ve been on Latuda. I started it when I was taking geodon because I was having a severe stiff neck. It’s called an extrapyramidal effect.

  • Charlie October 5, 2014, 3:11 pm

    This is bad sh#t. I’ve been on it for five days and have been sick every day. Severe severe headaches, nauseau, GI problems, anxiety, anger just to name a few. The side effects are not going away as I was told. I am getting off.

  • Hank September 26, 2014, 2:22 am

    I have been off of Latuda for over 3 weeks now. While I was on it I experinced extreme insomnia to the point where I only got 1-2 hours of sleep a night. I also experienced a lot of sweating. The worst side effect I experienced and still am is the act that my tongue is pressed up against the roof of my mouth continuously. Be careful with this drug!

  • Sarah September 2, 2014, 7:56 pm

    I have been on latuda for 3 months on 40 mg. I went down to 35 and two days later experienced horrible depression. I would say 10 mg is too much to titrate off try 5 if you can even tolerate that. Its a serious drug. Helpful but hard to decrease.

    • Natalie November 22, 2014, 9:31 pm

      How can you titrate 5mg? Latuda should not be cut and only comes in 20, 40,80,120,160mg tabs.

      • Wes September 11, 2015, 12:06 pm

        This is not true. I have been on Latuda over a year, the past 5 months at 10 mg. I routinely cut the 20 mg pill in half. My pharmacist said it was okay to cut Latuda tablets.

    • Ashley November 18, 2016, 3:34 am

      How did you do 5 mg decreases?

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