A 36-person experiment found that 18 Hz infrasound raised salivary cortisol and negative mood appraisal even though participants did not detect the infrasound above chance (p = 0.241).1 The result is a controlled acute signal, not proof that every real-world low-frequency noise complaint is physiologically caused by infrasound. Research Highlights Cortisol rose with infrasound: Infrasound …
A human, mouse, and zebrafish study linked long-term chlorpyrifos exposure to Parkinson’s disease risk, with the strongest exposure-duration estimate reaching OR 2.74 for workplace proximity across the 1974-to-index-year window.1 The paper is stronger than a single epidemiology result because animal experiments pointed to dopaminergic neuron loss, microglial activation, pathological α-synuclein, and autophagy dysfunction. Research Highlights …
A 40-rat early-life visceral stress study found auditory pathway sensitization without hearing-threshold loss: neonatal colorectal distension produced IBS-like visceral hypersensitivity, normal ABR thresholds, shortened auditory brainstem latencies, increased amplitudes, and 219 differentially expressed cochlear proteins.1 The result turns IBS-like stress exposure into a gut-pain and sensory-processing question. Research Highlights Visceral hypersensitivity was strong: At 20 …
A 2026 Generation Scotland study linked traumatic physical injury to diagnosis-stratified blood methylation differences in 4,308 people.1 The clearest recurrent-depression signal pointed toward oxytocin signaling and synaptic-plasticity pathways, but the result is still exploratory pathway evidence rather than a blood test for depression or PTSD. Research Highlights Recurrent depression carried the strongest phenotype signal: traumatic …
A 2026 review in the Japanese Journal of Radiology argued that amyloid PET has moved from an optional Alzheimer’s disease biomarker to a practical eligibility gate for anti-amyloid antibody therapy, while tau PET and FDG-PET answer different questions in the same clinical workflow.1 The key shift is not that every memory complaint needs PET; it …
A 2026 review of electroacupuncture for depression found a familiar split: mechanistic evidence is rich, but clinical proof remains uneven because representative trials ranged from 65 to 270 participants, used different sham or drug comparators, and often failed to connect stimulation parameters with biological endpoints.1 Electroacupuncture is plausible as a subtype-matched neuromodulation strategy, but it …
A 124-person study of euthymic bipolar disorder found that patients with early systematic antidepressant treatment history had higher negative affect, attentional impulsivity, non-planning impulsivity, and total BIS-11A impulsivity scores than matched patients without that history.1 The association is clinically cautionary, but the cross-sectional design cannot separate antidepressant effects from delayed bipolar diagnosis or more severe …