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Anterior Cingulate Sulcus Asymmetry Linked to Lower Delay Discounting

MHD featured image for anterior cingulate sulcus asymmetry and delay discounting.

A 2026 Human Connectome Project MRI study linked asymmetric anterior cingulate cortex sulcal pattern to lower delay discounting in 390 healthy young adults: asymmetric ACC morphology predicted a higher delay-discounting area under the curve, meaning delayed rewards lost less value.1 The finding is not a diagnostic scan for impulsivity, but it puts an early-formed cortical-folding …

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Ethiopia Somali Region Stigma Delayed Mental Health Care

MHD featured image for mental health stigma and care-seeking in Ethiopia's Somali Region.

A 2026 qualitative study from Ethiopia’s Somali Regional State found a harsh care-seeking pattern: mental illness was often recognized only when it looked like visible “madness,” was commonly explained through spiritual causes, and carried stigma severe enough to delay biomedical care.1 Research Highlights 16 interviews shaped the analysis: Warfa et al. interviewed health workers, service …

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Preschool Sleep Under 9 Hours Linked to Anxiety in 1,589 Children

MHD featured image for preschool sleep duration and anxiety symptoms.

A 2026 Shanghai study of 1,589 preschoolers found that children sleeping ≤9 hours at night had higher parent-rated anxiety scores than children sleeping >10 hours. The effect sizes were small, but the pattern appeared across total anxiety, physical injury fears, social phobia, obsessive-compulsive symptoms, and generalized anxiety symptoms.1 Research Highlights 1,589 preschoolers were analyzed: Zhang …

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Reward Activation Failed as Bipolar-Psychosis Endophenotype

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A 244-person functional MRI study found no significant evidence that ventral striatum activation during reward anticipation works as an endophenotype — a measurable trait used to connect inherited risk with diagnosed illness — for bipolar and psychotic disorders. Research Highlights The registered hypothesis failed: Barendse et al. found no significant ventral striatum reward-anticipation difference among …

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Drug-Induced Dystonia: Metoclopramide and Antipsychotics Lead FAERS

MHD featured image for drug-induced dystonia signals involving metoclopramide and antipsychotics.

A 2026 FAERS pharmacovigilance study of 28,938 dystonia reports found the strongest reporting signal for metoclopramide, while antipsychotics dominated the high-volume psychiatric medication signal and most timed cases began within 30 days of drug exposure.1 Research Highlights 28,938 dystonia reports: Chen et al. analyzed 27,618 patients represented in FAERS reports from Q1 2004 through Q3 …

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Pulse-Wave Harmonics Flag MCI During Cognitive Stress: 2.6-Point Gap

MHD featured image for pulse-wave harmonic coherence, cognitive stress, and mild cognitive impairment screening.

A 2026 community study of 101 older adults found that pulse-wave harmonics changed in a more organized way during a subtraction task in cognitively intact participants than in people with MoCA-defined mild cognitive impairment: amplitude-coherence scores averaged 9.00 vs. 6.40, a 2.60-point gap on a 0-10 scale. Research Highlights Cognitive stress exposed the signal: resting …

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Neighborhood Deprivation Linked to Faster Epigenetic Aging in 370 Adults

Editorial card showing neighborhood deprivation, lifetime adversity, and epigenetic clock acceleration.

A 2026 medRxiv preprint involving 370 healthy adults found that each increase in neighborhood-deprivation percentile rank was associated with epigenetic age acceleration on 3 of 4 second-generation DNA-methylation clocks, with lifetime adversity explaining 20.3% of the GrimAge association and 23.3% of the PCGrimAge association.1 Research Highlights 3 of 4 clocks accelerated: each increase in Area …

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