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Adult Hippocampal Neurogenesis Added 670,000 Rat Dentate Neurons

MHD featured image for adult hippocampal neurogenesis and dentate gyrus neuron turnover.

A 2026 rat study estimated that adult hippocampal neurogenesis added 670,000 dentate gyrus granule neurons from 2 to 18 months of age, but the total dentate gyrus population grew by only 385,000 cells because older developmentally born neurons were also being lost.1 The result makes adult neurogenesis look numerically larger than the usual “tiny trickle” …

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Fibromyalgia Costs in Saudi Arabia: $2,560 Annual Direct Medical Cost

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A 2026 Saudi tertiary-hospital study estimated that adults treated for fibromyalgia — chronic widespread pain with fatigue, sleep disruption, cognitive symptoms, and overlapping mood or medical problems — generated SAR 9,601.2 (USD 2,560.3) in annual direct medical costs per patient, with specialist visits and diagnostic procedures accounting for 96.3% of recorded spending.1 Research Highlights Annual …

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PHQ-15 and SSD-12 1-Week Versions Support Clinical Symptom Tracking

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A 2026 psychometric study of 354 Swedish participants found that 1-week versions of the PHQ-15 and SSD-12 mostly preserved internal consistency and construct validity, but reliability was acceptable mainly in clinical participants or when researchers averaged 2 timepoints. Research Highlights Clinical tracking looked more defensible than healthy screening: Hybelius et al. studied 194 people with …

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Teen Substance-Use Prediction in ABCD: Stable Signals, Small Effects

MHD featured image for teen substance-use prediction in the ABCD Study.

A 2026 ABCD Study preprint involving 11,868 youth found stable time-ordered predictors of teen substance-use initiation, but the adjusted effects were small: most estimates ranged from −0.01 to 0.02 initiation-probability points per 1-SD predictor increase. Research Highlights Large ABCD panel: Wei et al. analyzed 11,868 youth with repeated observations and interval-level initiation outcomes for alcohol, …

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Clomipramine Improved Alzheimer’s Mouse Memory by Blocking Itch in 45 Days

Editorial card showing clomipramine, Itch signaling, and Alzheimer's mouse-memory rescue with a molecular neuroscience background.

A 2026 iScience study found that 45 days of clomipramine improved spatial, working, and reference memory in female APP/PS1 Alzheimer’s-model mice, apparently by blocking the E3 ubiquitin ligase Itch rather than by clearing amyloid plaques.1 Research Highlights 45-day clomipramine signal: 6-month female APP/PS1 mice received 25 mg/kg clomipramine every other day for 45 days, then …

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tDCS Failed Visual Working Memory as Distraction Increased Orientation Bias

Editorial card showing visual working memory, tDCS electrodes, and distraction-linked orientation bias in a cognitive neuroscience task.

A 2026 two-experiment study found no visual-working-memory benefit from parietal or occipital transcranial direct current stimulation, while distraction unexpectedly made the cardinal-over-oblique orientation advantage stronger than it was without distraction: the pooled distraction-by-angle interaction had BFinc = 1021.671.1 Research Highlights Distraction strengthened the bias: pooled data from 68 analyzed adults showed a strong distractor-by-angle interaction, …

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