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Chinese Herbal Acupoint Patches Improved Sleep After Stroke in Small Trials

MHD card with a glowing outline of the sole of a foot wearing a square herbal patch, a dotted amber meridian line, a crescent moon, and scattered dried berries and cinnamon pieces on a warm dark background, illustrating herbal acupoint patches for sleep after stroke.

A 2026 meta-analysis of 7 small Chinese trials found that adding herbal patches on acupuncture points to usual stroke care improved self-rated sleep in 608 stroke survivors with sleep problems.1 The researchers rated that evidence as very low certainty, and safety was barely reported. Research Highlights Better sleep scores: across 6 trials (536 people), Pittsburgh …

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VR Training for Alzheimer’s Improved Memory Tests, Not Daily Function

MHD card with a VR headset and memory tiles: 11 study reports include 2 from the same cohort; memory test scores improved, with no clear gain in daily life.

A 2026 meta-analysis of 11 reports from small randomized trials found that virtual reality (VR) training modestly improved thinking-test scores in people with Alzheimer’s dementia (standardized effect 0.44), but it did not produce a clear benefit for everyday functioning, quality of life, or mood.1 The studies were small, several had design problems, and the researchers …

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Ultrasound-Guided Acupotomy Reduced Chronic Spinal Pain in 32 RCTs

MHD featured image for ultrasound-guided acupotomy chronic spinal pain meta-analysis.

A 2026 meta-analysis of 32 randomized trials involving 2,669 participants found that ultrasound-guided acupotomy reduced chronic spinal musculoskeletal pain, with pain intensity improving by SMD = −0.80 and disability by SMD = −0.99 on NDI/ODI measures.1 The direction is favorable, but all trials came from China and evidence certainty stayed moderate for pain and low …

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Substance Use Disorder Brain Connectivity in 53 Studies

MHD featured image for substance use disorder, resting-state fMRI, reward circuitry, and brain connectivity meta-analysis.

A 53-study resting-state functional magnetic resonance imaging (fMRI) meta-analysis found substance use disorder (SUD) linked to altered connectivity across prefrontal, striatal, thalamic, cingulate, and amygdala circuits. The most clinically relevant finding was an impulsivity correlation, not a diagnostic brain signature. Research Highlights Meta-analysis scale was meaningful: Zhang et al. pooled 53 whole-brain resting-state functional magnetic …

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GLP-1 Drugs Reduced Sleep Apnea AHI by 13.89 Events per Hour

MHD featured image for GLP-1 receptor agonists reducing sleep apnea severity and weight.

A 2026 meta-analysis of 4 randomized trials found that GLP-1 receptor agonists reduced obstructive sleep apnea severity by 13.89 apnea-hypopnea events per hour compared with placebo, alongside 12.46 kg more weight loss than placebo.1 The effect looks clinically meaningful for obesity-linked sleep apnea, but high heterogeneity means the result should not be flattened into “GLP-1 …

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AVATAR Therapy Reduced Auditory Hallucination Severity in 8 Trials

MHD featured image for AVATAR therapy and auditory hallucinations.

A 2026 meta-analysis of 8 controlled trials found that AVATAR therapy reduced auditory verbal hallucination severity after treatment, Hedges’ g = −0.40, 95% CI −0.54 to −0.25, across 978 participants.1 The signal is real, but the strongest reading is short-term symptom calibration rather than a finished replacement for standard psychosis care. Research Highlights Voice severity …

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