Mental Health DailyResearch. Evidence. Perspective.Published research on meta-analysis.
A 2026 meta-analysis of 54 human studies found that 8-hydroxy-2′-deoxyguanosine rose in Parkinson’s disease, while F2-isoprostanes did not show a statistically confirmed Parkinson’s signal; …
Read articleA 30-trial meta-analysis found that cholinergic modulators improved schizophrenia negative symptoms, SMD −0.42, while the overall total PANSS/BPRS effect was not statistically significant.1 …
Read articleA 2026 medRxiv meta-analysis of 27 trials found that transcranial direct current stimulation added to cognitive training improved global cognition immediately after treatment by SMD 0.36 com…
Read articlePatients with chronic insomnia frequently end up on both a sleep medication and cognitive behavioral therapy for insomnia (CBT-I), and a 2026 AASM meta-analysis of 15 RCTs from Buysse et al.…
Read articleA 2026 review of 52 studies found that chronic primary pain is linked to several physiological stress markers, especially cortisol, heart rate, heart-rate recovery, and mean arterial pressur…
Read articleAn Ethiopian umbrella review estimated perinatal depressive symptoms at 22.49% across 8 systematic reviews and meta-analyses. Antenatal and postnatal rates were similar, so the burden spans …
Read articleA 2026 systematic review and meta-analysis of randomized trials found no broad superiority for phase-based complex PTSD care across most outcomes. Affect dysregulation was the clearest excep…
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