One Session of tACS Changed Opioid-Cue Brain Activity but Not Craving
In 60 men with opioid use disorder, one tACS session changed cue-related brain activity and network coupling. Craving did not differ from sham.
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Published research on fMRI.
Social Anxiety and Depression Symptoms Linked to Avoiding Tough Judges
In a brain-scan study of 135 young adults, higher depression and social anxiety symptoms were linked to giving up rewards to avoid demanding judges, with a stronger threat response and weake…
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Social Anxiety: Prefrontal Connectivity Differs but Amygdala-PFC Doesn’t
The textbook story of social anxiety disorder is broken amygdala-prefrontal regulation — an overactive threat system the prefrontal cortex can’t calm down. A 2026 effective-connectivity stud…
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fMRI Low-Frequency Oscillation Tracked Nicotine Dependence and Arousal
A 2026 multi-cohort fMRI study found that a signal often treated as physiological noise tracked nicotine dependence, cue-induced craving, abstinence, and stimulant effects.1 During cigarette…
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Postpartum Depression Brain Activity: 12-Study fMRI Meta-Analysis
Resting-state fMRI studies of postpartum depression have produced inconsistent results for years. A 2026 voxel-based meta-analysis pooled 12 studies of 475 patients and found 4 reliable regi…
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Trauma Disrupts Parent-Child Fear Extinction in Youth With PTSD Symptoms
A 97-dyad adolescent fMRI study found that trauma-exposed youth with high posttraumatic stress symptoms did not use parent-observed safety learning in the usual way: their arousal rose to a …
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PTSD Counterconditioning Strengthened fMRI Safety Memory
A 2026 functional magnetic resonance imaging study involving 54 adults found that pairing a formerly threatening cue with positive images, a laboratory method called counterconditioning, str…
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