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Teen THC Increased Anxiety-Like Behavior in Adult Rats

A 2026 rat study found that 21 days of late-adolescent tetrahydrocannabinol (THC) exposure produced adult anxiety-like behavior in the elevated plus maze and weaker novel object recognition than vehicle exposure. The controlled animal result gives a biologically anchored model for why repeated high-THC exposure during development remains a real concern.1 Research Highlights Late-adolescent THC exposure …

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White Matter Hyperintensity Penumbra MRI Links Hidden Damage to Cognition

MHD featured image for white matter hyperintensity penumbra MRI and cognition.

A 245-person BeLOVE MRI analysis found that tissue immediately surrounding white matter hyperintensities already carried measurable injury: magnetization transfer saturation was lower inside lesions than contralesional white matter, β = −0.48, p < 0.001, and the gradient extended into normal-appearing tissue around the lesion border. The cognitive signal was narrower but clinically interesting: higher perilesional …

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Pareidolia Study: Natural Images Shift Illusions Toward Animals and Nature

MHD featured image for pareidolia, natural images, white noise, and animal-shaped visual illusions.

A 2026 experiment involving 81 healthy adults found similar pareidolia counts across natural and white-noise images, but different content: natural images favored natural-world categories (75.3% vs. 59.37%), while white noise favored human-created categories (27.59% vs. 14.53%). Pareidolia means seeing meaningful objects or patterns in ambiguous input.1 Research Highlights Image type changed the content, not the …

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tDCS Failed Visual Working Memory as Distraction Increased Orientation Bias

Editorial card showing visual working memory, tDCS electrodes, and distraction-linked orientation bias in a cognitive neuroscience task.

A 2026 two-experiment study found no visual-working-memory benefit from parietal or occipital transcranial direct current stimulation, while distraction unexpectedly made the cardinal-over-oblique orientation advantage stronger than it was without distraction: the pooled distraction-by-angle interaction had BFinc = 1021.671.1 Research Highlights Distraction strengthened the bias: pooled data from 68 analyzed adults showed a strong distractor-by-angle interaction, …

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Cognitive Reserve in First-Episode Psychosis: Education PRS Adds 4.2%

Photoreal illustration of brain with strengthening neural networks suggesting reserve and protection against cognitive decline.

A 2026 analysis of 174 people with non-affective first-episode psychosis found that cognitive reserve was tied to 3 signals available near illness onset: age at onset, family history of psychosis, and polygenic liability for educational attainment. Adding the education polygenic score raised the model’s adjusted R² from 13.5% to 17.7%, a real but modest gain …

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Alcohol & Brain Volume in Older Adults: Cortical Thinning & White Matter Loss in Heavy Drinkers (250g/Week) (2023 Study)

Alcohol’s effects on the brain, especially among the elderly, have long been a subject of scientific inquiry. A recent study from Gothenburg, Sweden, provides new insights into how varying levels of alcohol consumption impact brain structure in individuals aged 70 and over. This research sheds light on the relationship between alcohol intake and the aging …

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