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Small-Vessel Disease MRI Score Predicted 90-Day Cognition After Stroke

MHD featured image for composite small-vessel disease MRI and post-stroke cognitive recovery.

A 2026 medRxiv preprint involving 65 early subacute stroke survivors found that a composite cerebral small-vessel disease MRI score predicted 90-day cognitive recovery more reliably than any single input marker.1 Lower baseline burden predicted higher follow-up Montreal Cognitive Assessment scores (β = −0.19; p = 0.009) and remained associated after baseline cognition was included (β …

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rTMS Plus Risperidone Improved Schizophrenia Cognition

A 2026 randomized study involving 80 people with schizophrenia found that adding high-frequency repetitive transcranial magnetic stimulation to risperidone improved PANSS cognitive-factor scores and aggressive-behavior ratings more than risperidone alone over 4 weeks.1 Research Highlights Design was randomized but short: 80 patients were assigned to risperidone alone or risperidone plus rTMS, 40 per group, with …

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Ultra-Processed Foods Linked to Lower Attention in 2,192 Adults

MHD featured image for ultra-processed foods, attention, and dementia-risk scores.

A 2026 Australian study involving 2,192 dementia-free adults found that each 10% higher ultra-processed food intake was associated with 0.05-point lower attention and 0.24-point higher modified CAIDE dementia-risk score.1 The memory result was not significant, so the honest read is attention and risk-score signal, not global cognitive collapse. Research Highlights Attention was lower: Each 10% …

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Hypoglossal Nerve Stimulation Improved Sleep Symptoms More Than Cognition

MHD featured image for hypoglossal nerve stimulation, sleep apnea symptoms, and cognition.

A 2026 CARDIOSA-12 secondary analysis found that active hypoglossal nerve stimulation improved sleepiness, insomnia, snoring, and sleep-related function, but objective cognitive test performance mostly did not improve compared with partially therapeutic stimulation.1 Symptom relief and measurable cognitive recovery answer separate clinical questions in treated obstructive sleep apnea. Research Highlights Subjective outcomes improved: active HGNS improved …

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Antipsychotic Dose Was Not Linked to MoCA in Schizophrenia

A 2026 cross-sectional schizophrenia study found no meaningful association between antipsychotic dose and Montreal Cognitive Assessment (MoCA) performance in young, clinically stable outpatients. Cognitive scores related more strongly to symptom burden, illness duration, education, and age at diagnosis than to daily or 1-year cumulative antipsychotic exposure.1 Research Highlights Daily dose was not linked to MoCA: …

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Virgin Olive Oil Linked to Cognitive Preservation and Gut Diversity

MHD featured image for virgin olive oil, gut microbiome diversity, and cognition.

A 2026 PREDIMED-Plus cohort analysis linked higher olive-oil intake with 2-year cognitive preservation in 656 older adults, with each 10 g/day increment associated with higher global cognition change compared with lower intake (beta 0.044 z-score; 95% CI 0.013 to 0.075; p = 0.006).1 The more specific signal favored virgin olive oil and gut-microbiome diversity, while …

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Teen THC Increased Anxiety-Like Behavior in Adult Rats

A 2026 rat study found that 21 days of late-adolescent tetrahydrocannabinol (THC) exposure produced adult anxiety-like behavior in the elevated plus maze and weaker novel object recognition than vehicle exposure. The controlled animal result gives a biologically anchored model for why repeated high-THC exposure during development remains a real concern.1 Research Highlights Late-adolescent THC exposure …

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