A 2026 PLOS One study fine-tuned Qwen-2.5 and GLM-4 for psychology questionnaire generation and reported the largest gain in readability and comprehension difficulty: 3.41 to 4.66 on a 0–5 scale, a 36.7% relative improvement.1 The result supports item drafting inside a psychometric workflow, while clinical or research scale use still requires ordinary validation. Research Highlights …
A 2026 nationally-representative study by Johnson, Parker, and Wade in the Canadian Journal of Psychiatry tested ACE-style screening in 7,608 Canadian adults and replicated what US, UK, and New Zealand cohorts already found: predictive accuracy is poor, with AUCs of 0.62 to 0.67 across anxiety, mood, substance use, and suicidality — all below the conventional …
A 2026 preprint found that an independent supervisory safety agent detected suicide-risk signals in 205 of 224 synthetic evaluations, compared with 41 of 224 for native ChatGPT Health crisis safeguards.1 The result is a strong benchmark signal for external monitoring, not proof that AI systems can safely manage suicidal patients without human oversight. Research Highlights …
A 2026 preprint combining 2,189 university participants with 477 clinical patients with problematic sexual behavior found a gender-specific self-harm signal: women with problematic sexual behavior had higher non-suicidal self-injury risk, but clinical severity of problematic sexual behavior did not predict NSSI inside the patient cohort.1 Research Highlights Total sample was 2,666 people: Jiang et al. …
Transcranial direct current stimulation (tDCS) has been pitched as a scalable cognitive-enhancement tool for schizophrenia, where roughly 98% of patients show working-memory deficits, but a 2026 sham-controlled crossover trial from Ke et al. delivered the standard 1.5 mA anodal protocol over the right DLPFC to 27 stable patients and found no detectable benefit over sham.1 …
The depression-inflammation literature has firmly established that elevated inflammatory markers track with mood symptoms, but a 2026 study of 14,419 postpartum women from Xie et al. found the opposite pattern for postpartum anxiety: women with higher second-trimester platelet-neutrophil products and related immune-inflammation indices had substantially lower postpartum anxiety risk.1 Research Highlights Higher second-trimester PPN was …
Schizophrenia’s genetic architecture sits awkwardly between neurons and the immune system. A 2026 CRISPR screen of 30 schizophrenia-associated genes in human microglia-like cells found that several risk genes meaningfully alter how microglia engulf synaptic material, supporting the synaptic-pruning model at the functional gene level.1 Research Highlights 30 schizophrenia risk genes were knocked out one by …