Mental Health DailyResearch. Evidence. Perspective.Published research on Schizophrenia.
A 2026 case report described valproate 800 mg/day improving agitation in residual-phase treatment-resistant schizophrenia but being followed by hypoglycemia and pancytopenia; after discontin…
Read articleA 254-person FaceYourFears moderator analysis found that people with schizophrenia-spectrum paranoia and higher avolition or moderate-to-high delusion severity may improve more with virtual-…
Read articleA 2026 randomized study involving 80 people with schizophrenia found that adding high-frequency repetitive transcranial magnetic stimulation to risperidone improved PANSS cognitive-factor sc…
Read articleA 2026 meta-analysis of 8 controlled trials found that AVATAR therapy reduced auditory verbal hallucination severity after treatment, Hedges’ g = −0.40, 95% CI −0.54 to −0.25, across 978 par…
Read articleA 2026 ENIGMA structural MRI preprint involving 3,958 people diagnosed with schizophrenia and 5,489 controls found 2 cortical-alteration subtypes rather than 1 uniform brain pattern.1 The re…
Read articleA 30-trial meta-analysis found that cholinergic modulators improved schizophrenia negative symptoms, SMD −0.42, while the overall total PANSS/BPRS effect was not statistically significant.1 …
Read articleA 2026 systematic review argues that catatonia should be read as a limbic-cortical circuit syndrome, with motor shutdown tied to brain systems for threat, salience, motivation, and emotional…
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