A 2026 ENIGMA-OCD preprint tested a transformer model on resting-state fMRI from 1,706 participants and reached AUROC = 0.653 ± 0.039 for OCD classification.1 The more important result was the failure mode: held-out-site performance ranged from AUROC 0.427 to 0.819, which is exactly the gap clinical AI has to close before brain-scan diagnosis is credible. …
A 228-person randomized trial found a split result for workplace mental-health apps: executive-function training reduced anxiety and depressive symptoms at 12-week follow-up, while a self-guided CBT app improved workplace wellbeing without reducing symptoms.1 The mechanism claim was weaker than the outcome claim because measured executive-function change did not explain the improvements. Research Highlights 228 adults …
A 2026 qualitative study of a 10-week Danish Arts on Prescription program found that young adults aged 18 to 30 often described more stable daily routine, confidence, and belonging, but some activities also caused stress, fatigue, or discomfort.1 The useful interpretation is structured creative groups may help some disconnected young adults rebuild daily life when …
A 99-patient randomized trial found that adding esketamine to sufentanil patient-controlled analgesia lowered postoperative depression and anxiety scores at 24 and 72 hours after colorectal cancer surgery, while resting and activity pain scores did not differ by group.1 That pattern makes the result more interesting than simple pain relief: the mood signal was partly independent …
A 2026 longitudinal study involving 951 adolescents found 5 emotion-regulation profiles, not the 3-profile structure the researchers expected, and the clearest mental-health separation came from the adaptive and maladaptive profiles.1 Teen coping looked less like a single good-versus-bad scale and more like a pattern of motives, strategies, and beliefs about whether those strategies work. Research …
A 70-person COPD trial found that 12 weeks of app-based rhythm-guided walking plus singing improved shuttle-walk distance by 56.35 m and lowered HADS-anxiety by 2.31 points vs. usual care; rhythm-guided walking without singing did not clearly separate from usual care.1 Research Highlights Combined training beat usual care: the multimodule group improved incremental shuttle walking test …
A 2026 pilot trial tested a classroom program for children's climate anxiety: art projects plus guided discussion were supposed to help students express climate emotions and build coping skills. The intervention did not work better than waitlist control, but it also did not make children more anxious. Research Highlights The intervention failed to separate: 46 …