In 433 non-demented amyotrophic lateral sclerosis (ALS) patients, clinically significant anxiety was present in 18.2% for state anxiety and 13.9% for trait anxiety. The strongest predictor was not motor severity, cognition, or caregiver-rated behavior; it was depression, especially cognitive-affective depression symptoms.1 Research Highlights ALS anxiety was measurable but not universal: Aiello et al. found clinically …
The link between psychological stress and chronic inflammation is well-documented — what’s been less clear is which specific inflammatory proteins move with anxiety in real-world community samples. A 2026 analysis from Loomans-Kropp et al. measured a 33-marker panel in 190 minoritized and medically underserved adults from the Cancer Disparities Research Network and identified three biomarkers …
An 11-person case series tested delayed-release apple cider vinegar capsules in young adults who had gained weight while taking psychotropic medications, and metabolic markers carried more signal than weight loss. Research Highlights Feasibility was the strongest result: 11 of 12 enrolled participants completed the study, 10 of 11 completers missed 5 or fewer doses, and …
A 2026 mouse study linked cholestatic liver injury to smaller thalamic volume than control injury-free mice, broad thalamus gene-expression changes, and partial pathway rescue after systemic tumor necrosis factor neutralization. Research Highlights Thalamic volume decreased: bile duct ligation (BDL; a mouse model of obstructive cholestatic liver injury) reduced thalamic volume vs. sham surgery by magnetic …
A Saudi dental-clinic study found very high caries burden, but dental fear and anxiety were not the main adjusted explanation for dental caries. In 619 Al Ahsa patients, 89.5% had caries, 36.3% reported dental fear, and 25.8% reported anxiety; age, education, and oral hygiene carried a stronger caries signal than fear or anxiety.1 Research Highlights …
A 299-person remote randomized trial found that 10 min of daily focused-attention meditation reduced anxiety and mind wandering more than waitlist control, with the strongest gains among adults who started with higher internalizing symptoms. Research Highlights Anxiety improved in the randomized phase: Glick et al. randomized 299 meditation-naive adults and found greater 8-week Generalized Anxiety …
A 2026 rat study found that 21 days of late-adolescent tetrahydrocannabinol (THC) exposure produced adult anxiety-like behavior in the elevated plus maze and weaker novel object recognition than vehicle exposure. The controlled animal result gives a biologically anchored model for why repeated high-THC exposure during development remains a real concern.1 Research Highlights Late-adolescent THC exposure …