≡ Main Menu

Topamax (Topiramate) Withdrawal Symptoms + How Long They Last

Topamax (Topiramate) is an anticonvulsant drug that is used to help prevent seizures in epileptics. It was later approved by the FDA in conjunction with phentermine for weight loss. Although the two primary uses of the drug remain to treat epilepsy and to help people lose weight, it is prescribed by some psychiatrists to treat bipolar disorder. Despite the fact that it is used to help treat bipolar disorder, most evidence suggests that it is ineffective for that particular condition.

If you are on this drug to manage bipolar disorder, understand that it has not been proven therapeutically effective. Some newer studies suggest that Topamax may provide some benefit in treating borderline personality disorder, but further research is warranted. Researchers have noted that long-term effects of this particular drug have not been well documented and that using this drug to treat borderline personality disorder is not well-supported.

In the same regard, this drug has been utilized to help people with alcoholism, but there isn’t enough supporting research. Other investigational uses for this particular drug include: PTSD (post-traumatic stress disorder), tremors, eating disorders, smoking cessation, cluster headaches, and OCD (obsessive-compulsive disorder). Fortunately most people end up having more problems with side effects from the medication than they do with any sort of major withdrawal.

Factors that influence Topamax withdrawal

As with any drug, there are going to be various factors that influence withdrawal from Topamax. These factors include things like: how long you took the drug (time span), your dosage, how quickly you tapered, as well as other individual factors.

1. Time Span

How long were you on Topamax? Someone who was on Topamax for a longer period of time may experience a longer withdrawal period compared to someone who was only on it for a few weeks or months. If you took it for years and suddenly quit, it may take some time before you readjust to functioning without it.

2. Dosage (25 mg, 50 mg, 100 mg, 200 mg)

The initial target dose of Topamax for adults is 100 mg per day – typically divided into two doses. The maximum recommended dose is 500 mg per day divided into two doses of 250 mg. In the event that you are on a relatively high dose, it may take longer for your body to adjust to reductions in dose during withdrawal and therefore you may experience more discontinuation symptoms. People that are on higher doses tend to

3. Cold Turkey vs. Tapering

It is always recommended to conduct a gradual taper to prevent rebound headaches as well as seizures upon withdrawal. Those who are susceptible to seizures should take the time to follow a tapering protocol as opposed to quitting cold turkey. To be on the safe side, you may want to withdraw at a rate of 25 mg every 2 weeks. So if you are currently at 100 mg, cut your dose to 75 mg after 14 days.

Some suggest dropping 25 mg every week, which is a little bit quicker, but many people have successfully managed with that tapering protocol.  If these reductions are too intense, you could taper at an even slower rate such as 10 mg per week just to be extra safe. As long as you aren’t cutting from 100 mg to 0 mg or making drastic reductions in your dose over short terms, you should be able to avoid seizures and debilitating withdrawal symptoms. If you have any questions regarding your tapering, be sure to talk to a professional (e.g. a doctor).

4. Individual Factors

Although most research suggests that withdrawal from this particular medication should be relatively short-lived, many people have reported pretty severe symptoms weeks after their last dose. Just know that a lot of the symptoms that you experience will be related to how quickly you tapered, whether you are on any other medications, and how sensitive you are to withdrawals.

Some people may not notice much of anything when they quit taking the drug, while other people may feel relatively sick and unable to function. Just know that your experience with any drug is going to be unique – everyone is different. Having good social support, a withdrawal plan, and doing your best to stay productive can help take your mind off of symptoms and make for a quicker recovery.

Topamax Withdrawal Symptoms: List of Possibilities

Below is a list of symptoms that have been reported during withdrawal from Topamax. Understand that you may not experience all of the symptoms listed below, but you may experience some. Keep in mind that the severity of the symptoms and how quickly you recover from them will be an individual experience.

  • Anger: If you find yourself prone to bouts of anger, just know that it could be due to withdrawal from the medication. Some people have reported that they notice themselves becoming angry during withdrawal when they didn’t have any anger problems prior to using this medication.
  • Anxiety: Many individuals report feeling extra anxious when they reduce dosage and/or discontinue the medication. Although the exact cause isn’t known, it may be due to the effect that this drug has on the GABA receptors. It may take some time for the anxiety to subside, but everything should return to normal.
  • Appetite changes: If you notice that your appetite increases when you quit the medication, this is a normal reaction. Topamax has been approved to help people lose weight and it tends to suppress appetite. When you stop taking it, your appetite may temporarily increase and/or return to baseline.
  • Concentration problems: It may be particularly difficult to concentrate during the acute withdrawal period. You may have a difficult time staying focused at work and/or completing normal tasks involving critical thinking and planning.
  • Confusion: The combination of physical withdrawal symptoms as well as concentration difficulties can lead people to feel “confused” for a few days of withdrawal. The confusion may persist for a week or two, but eventually you should be able to think clearly again.
  • Dehydration: This isn’t necessarily a common withdrawal effect, but some individuals have reported dehydration during withdrawal. It is always recommended to stay hydrated during withdrawal because it helps flush the system of the drug. Don’t overdo it, but drink a healthy quantity of water.
  • Depersonalization: Feeling unlike your normal self is something a lot of people report while on this drug as well as when they quit. Some individuals have gone as far as to say it changed their “personality.” It may have changed it while you were on the drug, but as time passes off the drug, you will eventually return back to normal.
  • Depression: Some people end up experiencing depression on the drug as well as when they withdraw. If you didn’t have any sort of severe depression prior to taking the drug, then your mood will return to normal after you quit.
  • Dizziness: This is perhaps the most common withdrawal symptom from any medication along with headaches. Many people have reported dizziness and vertigo immediately after they quit. The dizziness may last for a couple weeks, but should gradually diminish as time passes.
  • Fatigue: Don’t be surprised if you feel pretty tired during the withdrawal period. You may notice that you have low energy and want to sleep more than usual. After a couple weeks your energy levels should pick back up.
  • Headaches (Migraines): A lot of people take Topamax to help with cluster headaches and migraines. Don’t be surprised if you experience rebound headaches when you discontinue the medication. Additionally even if you didn’t have migraines prior to taking the drug, you may end up dealing with headaches for a few days as you withdraw from the drug.
  • Insomnia: Some people notice that they are unable to sleep when they quit taking this drug. It is thought that the increased anxiety as a result of GABA changes can lead to insomnia. Do your best to reduce your arousal with relaxation exercises if you are experiencing insomnia.
  • Irritability: You may notice yourself becoming increasingly irritable during the withdrawal period. Just keep in mind that this is temporary and a result of your brain readjusting to normal function without the drug.
  • Mood swings: Some individuals have experienced changes in mood upon withdrawal. One minute you may feel angry, the next depressed, the next more like your normal self. As time passes, your mood will stabilize.
  • Muscle pain: A common reported withdrawal effect is that of muscle weakness and pain at the joints. This could be due to the fact that your body is now functioning without the influence of a drug and is no longer getting the subtle pain relief and muscle relaxation that the drug may have been supplying.
  • Nausea: You may feel nauseated during withdrawal as this is a normal reaction to withdrawal from most medications. The nausea is typically not overwhelming and will likely subside within a week or two.
  • Panic attacks: If you experience anxiety and allow it to get out of hand, it may lead to panic attacks. In part this may be due to changes in the GABA receptors during withdrawal. As long as you taper slowly and do your best to practice relaxation exercises if you experience intense anxiety, panic attacks shouldn’t be long lasting.
  • Seizures: It is important to avoid quitting this medication “cold turkey” as you may experience rebound or withdrawal seizures if you aren’t careful. Therefore always follow the protocol as issued by your doctor and report to your doctor if you experience any problems.
  • Shaking: Some people have reported experiencing “shakes” and/or tremors when they discontinue. These should not last more than a couple days unless you quit cold turkey from a high dose.
  • Sweating: In some cases people have intense sweats throughout the day and while they sleep during withdrawal. This may be a detoxification mechanism by the body to help itself readjust to functioning without the drug.
  • Thought changes: Some people have noticed that their thoughts are weird or “odd” during withdrawal. Additionally others have noted that this drug changed the way that they think and/or their entire personality. Once you are off of the drug for awhile, your personality and thoughts should return to normal.
  • Vision changes: A troubling side effect that people report while on the drug is changes in vision and eyesight problems. During withdrawal, people have noted blurred vision and visual changes. In most cases, these changes in vision should return to normal over time.
  • Weight gain: Since this drug is used to help people lose weight and it inherently suppresses appetite, many people gain back the weight that they lost while taking it. Don’t be surprised if you gain a little weight once you withdraw.

Topamax Withdrawal Duration: How long does it last?

There is really no telling how long the withdrawal from Topamax is going to last. Most people suggest that it takes anywhere from a few days to a few weeks to be free of withdrawal symptoms. The half-life of the drug ranges from 19 to 25 hours, meaning it could take over 2 days for the drug to leave your system. Most reports suggest that there isn’t a protracted withdrawal syndrome associated with Topamax, so no need to panic.

Many people experience the usually mental fogginess, low energy, and thought changes for a few days, and end up returning to normal relatively quickly. Some people actually feel better within a couple days of stopping Topamax. Obviously it may take your body longer to adjust if you were on a relatively high dose for an extended period of time and/or you quit cold turkey.

There aren’t many horror stories regarding Topamax withdrawal like there are other drugs. During the withdrawal, it would be in your best interest to make sure that you get plenty of sleep, eat healthy, and get some light exercise (e.g. go for a walk). If you feel anxiety and/or possible panic, take the time to utilize some sort of relaxation techniques.

Most people end up feeling as though they have fully withdrawn within a couple weeks after discontinuing. If you still don’t feel better after a couple weeks, just know that everyone reacts differently to withdrawal. Some people may experience symptoms for a longer time than others upon discontinuation.  Do your best to stay productive, engage in healthy habits, and eventually you will feel fully recovered from the withdrawal period.

If you have been through Topamax withdrawal and/or are currently in the process of withdrawing, feel free to share your experience in the comments section below. Sharing your experience may prove to be very helpful to another person going through the same thing as you.

Related Posts:

{ 301 comments… add one }
  • Beth February 17, 2018, 11:36 am

    I was in 200mg for nearly 10 years for migraines. So far I’m down to 100mg taking myself off and the side effects are invading my personal and professional life. Going without sleep, being anxious, irritable, outbursts of anger, and sweating just seems to make all that worse. I sought out help from a nutritionist who put me on a clean diet, detox tea, activated charcoal, a vitamin B complex, magnesium, fish oil w/ D and CBD on top of my regular multivitamin.

    I noticed it take the edge off the symptoms. It was a bit costly but I have been on Topamax a decade and fully intend to get off in one try. I have had a hysterectomy last year and been put on estrogen. They believe now that was the cause of my migraine and other issues. The symptoms I described did not start until the day I cut my Topamax dose. My hysterectomy was a blessing and a success.

  • charlotte austin February 9, 2018, 6:56 pm

    I’ve been on Topamax for about 10 years I moved to another state and it’s hard to find a doctor. I’ve been without my medication for about five days and I’m starting to feel really bad. I’m getting headaches I’m not eating well, so I’m gonna see if I can just wean myself off.

    I take 100 mg in the morning and 100 mg at night. Right now it’s not too bad I mean I can barely remember stuff and I’m always shaky and nervous but let’s see will happen because I don’t want to get worse than what it is. I had no idea this medication could do all these things to you.

  • Annie January 30, 2018, 10:29 pm

    My 67 y/o husband took Topamax 100 mg a day for 2 months in conjunction with Phentermine for weight loss. 2 weeks after starting he began loosing his words , asking the same question 2-3 times during a conversation and loosing small tracts of time. Plus anxiety and panic attacks are daily.

    His MD just began a taper down of 50mg daily for a week then 50 mg every other day for a week then stop. My question is has anyone else suffered the memory loss with this med and how long after withdrawal before these symptoms stop? So scared and concerned for my sweetie.

  • Miriam Grant January 27, 2018, 10:16 pm

    I’ve been on Topamax 50 mg twice a day for migraines for 4 years. I finally decided to stop talking it after I couldn’t remember the simplest things. I was having horrible memory problems and brain fog, to where I seriously thought I was losing my mind.

    I’m currently tapering off from 50 mg to 25 for 10 days, then 25 every other day for 5 days as told by my doctor. I’ve experienced, hot and cold flashes and mental fog and small panic attacks. If I could go back I would have never started this drug.

  • Kelly January 22, 2018, 11:05 pm

    Hi, I just wanted to come and share my experience of weaning off topiramate. I was on it for 4 months looking to control my extremely infrequent focal seizures. This is my 5th attempt at finding an AED I can tolerate and I’m desperate to get driving again, so I persisted past early weeks of feeling completely rubbish and eventually, very slowly titrated up to 100mg.

    Once I stabilized at this dose, I felt completely fine – but then I had some auras just before my morning dose (I’d never had auras before, but given my type of epilepsy, this made sense), so drs gradually increased to 200mg per day. Due to some side effects suddenly having a severely detrimental impact on my career, it became apparent that although I ‘felt’ fine, I actually wasn’t fine at all.

    My dr agreed I could wean off rapidly and helped me to do so. I won’t put the details of the schedule here as I wouldn’t suggest anyone does this without medical supervision, but I went from 200mg per day down to 0 per day within a much shorter period of time than usual (not cold turkey, but very, very fast). My career was literally in jeopardy, and I was desperate – so my drs and I both felt it was worth accepting the risk of rebound seizure and a few unpleasant weeks.

    Initially I felt very ‘twitchy’ and incredibly restless, but it wasn’t nearly as bad as I expected. I had a few afternoons where I had a minor headache, and a few occurrences of aura just before my next dose. I had 2 days where I felt like I had a cold coming on (but this never happened), a bit of an upset tummy that I assume was related but this was tolerable, and a few nights where it was difficult to fall into then stay in a deep sleep.

    Finally, right at the end, I felt vaguely dizzy all of the time – but this was so vague I sometimes felt like I might be imagining it. The day I stopped altogether, I had one episode of severe depersonalization that passed within seconds, and later, another aura. Best of all – even as the dosage dropped, the issues with my work resolved.

    So for me at least, the withdrawal process was not nearly as bad as it has been for many others who have commented here, even though I weaned off super fast. But given what I’d read on this page and others, I had expected the experience would be horrific, and it just wasn’t. I’ve been completely off topiramate now for a few days, and I do feel like myself again, except for a little lingering fatigue and maybe a tiny bit of lingering short term memory degradation – but I’d say that’s already getting better every day.

    I just wanted to share a positive story here to give some hope to others who might be weaning off. It’s not always a horrendous process. Good luck to you all.

  • Melissa Heisey December 14, 2017, 8:14 pm

    I am so glad that I found this article. I was put on 50 milligrams of Topamax a day after having a Thunderclap migraine. I hate this medicine and I am really upset with my doctor for not properly giving all the upfront information about it! I could be the poster child for the side effects of this drug.

    Its horrible! I have a job that requires concentration and being precise and I feel like I have my head in the sand for most of the day. I can’t concentrate on anything or finish my sentences. I didn’t even make it a full month on this medication.

    After I figured out that is was the medicine that was actually making me worse, I cut my last week of pills in half and tapered myself off this drug. Now I am experiencing vision issues and dizziness. Hoping this doesn’t last long.

  • Ali December 13, 2017, 5:38 am

    I have been taking between 75-150mg of Topamax for 2 years for migraines. Have tapered for several months now to nothing. Having a lot of withdrawal symptoms to the point where I present as manic/depressive (or bipolar). Feel like anxiety had hit the roof, muscle pain, fatigue, insomnia, very moody, combative and all the while feeling like I live in a brain fog. Hope it gets better soon.

  • James Lacewell March 21, 2017, 1:38 pm

    I was on Topamax for 6 months for migraines and seizure-like episodes. My doctor recommended an alternative treatment and I tapered off of my 100 mg per day dosage over a 2 week period. That was three months ago and I am still suffering from insomnia, anxiety and minor depression.

    It has been awful. My doctor said they could put me on an antidepressant for the anxiety and depression, but I don’t want to get dependent on another drug and then face more withdrawal symptoms at some point. Has anyone else had the symptoms last this long? Any advice?

    • Gina March 29, 2017, 1:36 pm

      Yes, still struggling with withdrawal. I went from 50 milligrams to 25 last June, and became very depressed. I recovered a bit with the use of Zoloft, and then stopped the 25 milligrams of the beginning of February, and things have gotten bad again. I don’t know how long it will last. I feel like perhaps my brain is permanently altered from taking Topamax for 4 years. I was never on a very high dose, usually just 50 to 75 milligrams.

  • Jen March 7, 2017, 5:07 am

    So relieved for finding this forum! I think I was only on topiramate for maybe 2-3 weeks tops. Never upped my dose. Dr prescribed for eating disorder control. Decided I didn’t like being foggy and exhausted all the time so quit cold turkey. Already prone to anger/anxiety/depression and now my anger is out of control. Debating if I should get back on just to taper off.

    • Gina March 29, 2017, 1:38 pm

      If you can, stick it out. You weren’t on it too long, should be easier to recover. Good luck!

  • Colleen February 28, 2017, 12:16 am

    I have been trying for the last month to taper down my Topamax from 500mg would like to get down to 200 or 100mg. So glad I found this site was feeling awful, couldn’t understand why have only reduced 50 mg so far tried 25 mg more this week and I have been so tired, dizzy and nauseous. At least now I can understand why… I am going to try and cut the 25’s in half. Thanks for the support!

  • Melissa February 12, 2017, 1:07 pm

    This is such a needed website! So much pertinent information. I too had been on Topamax 100 mg for 10+ yrs for migraine issues. Recently I’ve made healthy choices with my lifestyle, going Vegan and cutting out sugar, and I wanted to go off meds.

    I love my doctor but he’s never been the best at advising me with proper protocol. I cut back to 50 mg and then went to every other night. After a couple few weeks I thought that should do it. After only 3 nights without it, I suffered tremendously!

    I had the worse migraine all day and was nauseated all day. In bed all day and then finally took 50 mg that evening. Next morning still feeling a bit shaky. Not worth going thru that again. Will slowly decrease to 25 mg over a longer period of time and hope to eventually get off of it one day.

  • Brianna February 7, 2017, 10:34 pm

    I’ve been off Topamax since January 30. I was taking 50 mg twice a day. Most of the time I feel okay – I’m sleeping a little better, although I’m still pretty tired, but the rebound headaches are torture. It’s just constantly there and I can’t deal with it – nothing provides relief – not ibuprofen or Frovatriptan. Does anyone have any advice? How long did the rebound headaches last?

    • James Lacewell March 21, 2017, 1:48 pm

      My headaches have been controlled by drinking plenty of water, a balanced diet, reduced caffeine, exercise and ibuprofen. You may have tried this already. Hope you find relief soon!

  • Marcy McCahan February 5, 2017, 3:56 am

    I started Dopamax 14 years ago. My pdoc put me on it to help me loose the 35 lbs. I’d gained from the depakote I’m on. Went up to 200 mgs. And it worked taking that weight off! Plus it made me very manic a lot which was fun. Better than being depressed. But I hated the dumbness. And it’s just gotten worse over the years.

    Besides this drug, I’m on four others 😟. I’ve weaned off of much of the depakote. But I’m just starting on tapering topamax. I’m down to 100 mgs. A miracle happened a few months ago. I went to get my prescription filled and instead of the 200 mg pill they gave me 100 mgs. So I took them not realizing the difference.

    I did that for over a month and finally saw what happened but never noticed any withdrawal. Only slightly for a couple of days and I thought it was allergies. I had dropped 100 mgs all at once! Wow. Wish it was always that easy. Now I’m cutting 25 mg pills into quarters and going slow. Have 100 mgs. to go.

    I’m getting clearer headed. I want to get off of as many of my pills as possible. Taking depakote, Wellbutrin, topamax, celexa, xanax. Ick… way too many. I want my life and mind back. I’m tired of being stuck on the couch and feeling like I have gum in my head all the time. I want to live! I want to see color in the world again and notice things around me again and feel feelings again!!!

  • MK January 28, 2017, 3:34 am

    I took 100mg-150mg each day for 3 years and my migraines eventually returned, so I tapered off recently. When I started the doses, I lost 20lbs (I’m not overweight), patches of hair, and had severe trouble remembering basic things like words, tasks, etc. Now that I’ve been off for a month, I’ve experienced some minor weight gain, severe fatigue, listlessness, vision problems, and depression to the point of breaking down into crying spells and wanting to withdraw from my friends and family. After reading this article I am hoping that I can return to my normal self because I’ve never had depression issues or fatigue before. I’m afraid my eyesight is just worse altogether.

    • James Lacewell March 21, 2017, 1:53 pm

      I’ve had the depression as well. It’s been 3 months but I feel like it’s going away. My doctor recommended exercise, fun activities, redirecting sad thoughts, balanced diet and staying active. Good luck!

    • Gina March 29, 2017, 1:41 pm

      Your experience is the exact same as mine: Some minor weight gain, severe fatigue, listlessness, vision problems, and depression to the point of breaking down into crying spells and wanting to withdraw from my friends and family. I am so tired, so hungry all the time. Have been off Topamax since Feb 1.

  • Belle January 22, 2017, 4:45 pm

    I started taking 100 mg of Topamax and went up to 200 mg after six months. After I began taking Topamax and then increased the dosage, I experienced severe depression, anxiety and exhaustion – I could not get out of bed. Each time the symptoms subsided after four weeks or so. My neurologist prescribed it for the basal migraines I frequently had (and are breaking through again).

    The Topamax has stopped working. Therefore my neurologist is taking me off of it after five years or so – not sure how long. But the weaning process is supposed to take place within ten days. Directly afterward I am to stop Primidone, and then Effexor. After reading this article and the comments (thank for all of the the input), I realise there is a reason why I feel so awful going from 200 mg to 25 mg of Topamax within seven days.

    I am going back up to 50 mg of Topamax and will then see how I feel. I’ll go from there. If and when I am off of Topamax I will give my body a long break before weaning from anything else. I continually kick myself for not asking the right questions of my doctors. Just once I wish I could fully trust a doctor, but after twenty-five years I know I must be my own advocate.

  • sarah January 18, 2017, 3:57 pm

    I had been taking Topamax 400mg PO every day since summer of 2014. My MD cut me down to 200mg PO daily a couple months ago. It was originally prescribed for migraines but I was also on it to treat my bi-polar disorder. I stopped taking this medication cold turkey and have ended up suffering from most of the symptoms above.

    I have been off of this medication for a week now and still do not feel like myself. I am tired, feel like sleeping all day, have had extreme bouts of anger (like I have never had before), I am nauseous and don’t feel like eating, and find myself crying a lot because I am overwhelmed by things that wouldn’t normally be overwhelming for me to deal with. I am kicking myself in the ass that I did not taper off this medication as opposed to going cold turkey.

    I highly recommend that anyone coming off this medication talk to their MD and get a proper taper schedule before stopping this medication.
    Hope this helps. Comments are welcome.

  • Ariana December 26, 2016, 6:02 am

    My sister has epilepsy and a bipolar disorder which causes her to become very angry and violent and she has been taking topamax for the past 16 years. She decided that the medication was no longer helping her with seizures or with her bipolar disorder and decided to go see a different Neurologist than the one she usually goes to.

    This neurologist recommended she stop taking Topamax, so she did and then everyday she started having anxiety and panic attacks that lasted an hour. She shakes, screams, and her body turns bright red! I would like to know what others like her have done to relieve withdrawal symptoms like anxiety and panic attacks? Any advice will help thanks!

  • Rivetted December 21, 2016, 12:52 am

    I have been on the drug for 4 years @ 100mg daily for migraines. It worked great, until I can’t remember my kids birthdays or how old I am. I’ve been detoxing for a few weeks with a taper system but decided not to refill & try to go cold turkey the rest of the way. Insomnia, excessive joint paint, headaches that remind me of why I started the med & some very location specific ones due to the detox.

    I am frustrated! It seems like I’m never going to be free of pain in someway or the other. This is my 2nd detox, the headaches got the best of me last time, but this is worse. The symptoms don’t wane. I can’t see, I can’t speak, I’m dizzy, I’m nauseated, I’m in pain. I do massage therapy, acupuncture, yoga, eat healthy all in the hopes of staving off pain/ discomfort that I can grow through… there’s no growing through this.

    This is a fog that I am anxious to have clear so I can see whats ahead.

  • Linda Hilgenkamp December 11, 2016, 6:25 pm

    I decided to discontinue taking Topiramate 100 mg. daily due to severe hair loss and memory problems such as getting lost, can’t remember words phrases, my own address, etc. I have a master’s degree and feel like my ability to communicate was at a first grade level. I had been on it for 3 years and didn’t know this drug may be the cause.

    I had been taking it for seizure related and migraine headaches. I dosed down very slowly and have been off of it for 2 months. My side effects during and shortly afterward were rebound headaches, blurred vision, insomnia and increased appetite. All the side effects have become much better.

    I have not gained any weight back. This is probably due to the fact that I never had much to lose in the first place and I always eat very healthy. I am a borderline diabetic and have eaten frequent, but very small portions at a time for many years, to stabilize my blood sugar.

    I have read all the comments and can’t find any one off the medication for a significant amount of time. What I really want to know is if your cognitive function returns, as so far my memory problems continue. Please tell me this is not permanent!

  • Izzy December 9, 2016, 6:45 pm

    Topamax is a nightmare. 3 months after I tapered off and I’m still feeling the huge mind fog and can’t make a sentence. I really hope it will go away, otherwise I have no idea what I will do. I used to be a sharp and talented cookie, I feel like an idiot now.

    The recall issue is the most problematic and both short and long memory. Overwhelming concentration issues. Keeping a conversation is just so difficult when you can’t recall words you have known all your life.

    They are somewhere there (just like all the rest of the lost memory) but it feels like they’re locked up somewhere without any natural smooth direct access to it. So frustrating and embarrassing. DON’T Ever TAKE IT!!! Try CBD instead.

  • Tonya November 29, 2016, 4:07 pm

    This was very helpful information and I’ve been taking Topamax for several years now. I had been suffering from migraines for almost 20 years and although they increased my dosage to 100mg daily I was still having more migraines than I should have. Most times when I took it my head would burn as if I had sores on my brain and I wanted to stop taking it.

    I had a car accident on 28 July 2016, got a concussion and could not keep up with my dosage. By 30 July I had completely stopped taking Topamax. At first all I did was sleep, didn’t want to eat or do anything but things got better. Unfortunately, three months later and I am still lethargic, it’s very hard for me to get motivated and I have gained 15 pounds!!

    It’s not that I eat more but I’m gaining weight almost every day even when I can get it together and exercise. I do not want depression to set in and I know that I need to see my doctor but I don’t want to be handed more pills. I still get headaches but they are nothing like the severe migraines I had while on Topamax.

  • Diane DeLorenzo November 18, 2016, 4:45 pm

    I have been on Topamax 75mg for migraines for a couple of years now and remember how hard it was to adjust to the side effects which took about two months. I lost about 20 pounds, have poor concentration and cognitive issues but did cut my headaches in half. Now I have to come off because I have kidney stones on both sides; not necessarily because of the Topamax (had them in the past) but it can make them worse and now I am worried about the withdrawal symptoms.

    My Dr. has me tapering 50 mg for three weeks, 50 mg for 2 weeks then 25 for 3 then 25 mg for 2 then stop. I am grateful for this website and find comfort in sharing this experience with others. Thank you and will keep you posted.

  • Kristie November 16, 2016, 7:09 am

    I’ve been on Topamax 100mg at night for several years. It helped my migraines/headaches… however I too have had increase problem in word finding and memory. I can not remember names of people or my own address for several minutes until I can finally grab them and say them. My MD has dropped me to 50mg at night x1 wk then supposed to stop.

    I have a horrible appetite right now with this transition off… and I have some 25mg tabs in the home and am going to take those for a week prior to stopping, but it sounds like that is still really fast. I have had 3 migraines already in the first week too. :( I am glad I am not alone though with the cognitive changes… being 44 and not being able to remember things is really scary and just not right.

Leave a Comment