Mental Health DailyResearch. Evidence. Perspective.Published research on brain aging.
A 2026 Molecular Psychiatry analysis from the Rhineland Study found that blood-derived microRNA signatures were associated with hippocampal brain structure: 6 microRNAs linked cross-sectiona…
Read articleA 2022 Nature Communications study used non-contrast 3D T2-FLAIR magnetic resonance imaging (MRI) to map human brain lymphatic signals in living people, including apparent channels from cran…
Read articleA 2026 quantitative MRI preprint reanalyzed 138 healthy adults and found that multivariate modeling detected coordinated age-related shifts across myelin-sensitive, iron-sensitive, and water…
Read articleA 2025 Nature Aging study found that hippocampal ferritin light chain 1 (FTL1) rose with age in mouse neurons, tracked poorer cognition, and became experimentally reversible in old mice. Thi…
Read articleA Nature Communications study found that old vertebrate brains lost almost 40% of cysteine protease deubiquitylase catalytic activity with age, despite relatively stable protein abundance.1 …
Read articleA 2026 mouse and cell study found that ATP11B loss pushed aged brains toward hippocampal iron accumulation, mitochondrial dysfunction, neuronal ferroptosis, and worse memory behavior than wi…
Read articleA 245-person BeLOVE MRI analysis found that tissue immediately surrounding white matter hyperintensities already carried measurable injury: magnetization transfer saturation was lower inside…
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