Mental Health DailyResearch. Evidence. Perspective.Published research on amyloid beta.
A 2026 Molecular Psychiatry study found that oral FP802 disrupted the NMDAR/TRPM4 death complex and preserved memory-task performance in 5xFAD Alzheimer’s mice treated for 3 months.1 The fin…
Read articleA preprint in 84 older adults with epilepsy found that abnormal Alzheimer's-related blood biomarkers were common, but the biomarker categories did not line up neatly with cognitive impairmen…
Read articleA 2026 review argues that neurovascular-unit dysfunction may precede amyloid-beta generation in Alzheimer’s disease and then synergize with amyloid deposition, tau pathology, inflammation, a…
Read articleA 2026 medicinal-chemistry study found that thymol carbamate TC-6 inhibited human butyrylcholinesterase at 3.6 nM, showed more than 2,500-fold selectivity over human acetylcholinesterase, cr…
Read articleA 2026 mechanistic Alzheimer’s study found that suppressing NDST3 shifted lysosomal pH in APP695Swe neuronal cells from 5.6 back below 5.0, then reduced amyloid-β, MAPT/tau pathology, neuron…
Read articleA 2026 single-cell and spatial-transcriptomics study of 21,156 brain immune cells found that late amyloid disease shifted interferon-driven neuroinflammation from microglia toward plaque-ass…
Read articleA 2026 iScience study found that 45 days of clomipramine improved spatial, working, and reference memory in female APP/PS1 Alzheimer’s-model mice, apparently by blocking the E3 ubiquitin lig…
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