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PTSD Counterconditioning Strengthened fMRI Safety Memory

A 2026 functional magnetic resonance imaging study involving 54 adults found that pairing a formerly threatening cue with positive images, a laboratory method called counterconditioning, strengthened later neural safety-memory signals in people with posttraumatic stress disorder. The experiment measured fear-learning biology, not PTSD symptom improvement after therapy.1 Research Highlights 54 adults were analyzed: Cooper et …

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Low-Dose Oral THC Did Not Reduce Stress Memory Distress: 36-Adult Trier RCT

Stylized Trier Social Stress Test memory scene with THC capsule and stress-response signals, representing a randomized trial showing no reduction in stress-memory distress.

Cannabis users often say the drug helps them blunt stressful memories. A 2026 randomized trial of 36 healthy adults tested low-dose oral THC against placebo during retrieval of a standardized lab stressor, and on every subjective and physiological measure that mattered, THC did nothing.1 Research Highlights 36-adult, 3-arm RCT: participants got placebo, 5 mg oral …

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Rwanda Resiliency Training Improved Forgiveness and Social Cohesion

MHD featured image for Rwanda Community Resiliency Model training and social cohesion.

A 2026 randomized comparison study of 152 Rwandan genocide survivors and released perpetrators found that 3-day Community Resiliency Model training improved social cohesion, compassion, forgiveness, and resilience over time, with social cohesion F(1) = 36.1, compassion F(1) = 131, forgiveness F(1) = 19.8, and resilience F(1) = 8.10.1 Mixed survivor-perpetrator groups improved slightly more, but …

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STAIR-R Did Not Beat Supportive Care for Refugee PTSD

A pilot randomized trial involving 71 refugees with posttraumatic stress disorder found large symptom improvement after narrative exposure therapy-based care, but adding refugee-adapted emotion-regulation training before narrative exposure therapy did not outperform supportive problem-solving before narrative exposure therapy in the full sample.1 Research Highlights 71 refugees were randomized: 35 received STAIR-R plus narrative exposure therapy, …

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Major Upper-Extremity Amputation Raised Mental Health Odds

Major upper-extremity amputation was linked to substantially higher odds of new mental-health diagnosis, antidepressant initiation, and psychotherapy claims than minor upper-extremity amputation in a matched national database study. The clearest clinical implication is early mental-health screening after major limb loss, not waiting for distress to surface months later.1 Research Highlights 2,452 matched patients were analyzed: …

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Ethiopia Somali Region Stigma Delayed Mental Health Care

MHD featured image for mental health stigma and care-seeking in Ethiopia's Somali Region.

A 2026 qualitative study from Ethiopia’s Somali Regional State found a harsh care-seeking pattern: mental illness was often recognized only when it looked like visible “madness,” was commonly explained through spiritual causes, and carried stigma severe enough to delay biomedical care.1 Research Highlights 16 interviews shaped the analysis: Warfa et al. interviewed health workers, service …

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