Mental Health DailyResearch. Evidence. Perspective.Published research on Drugs.
GLP-1 receptor agonists (semaglutide, liraglutide, tirzepatide) act on the brain as well as the gut, and a 2026 real-world cohort study from Kamel-Abusalha et al. propensity-matched 118,993 …
Read articleRestless legs syndrome (RLS), now also called Willis-Ekbom disease (WED), is a sleep-disrupting neurologic disorder that affects roughly 20–30% of pregnancies in some series and is linked to…
Read articleA 2025 iScience study found that nighttime caffeine increased motor impulsivity in Drosophila, with dose-dependent loss-of-inhibition events across n = 30-32 flies per behavioral condition a…
Read articleA 99-patient randomized trial found that adding esketamine to sufentanil patient-controlled analgesia lowered postoperative depression and anxiety scores at 24 and 72 hours after colorectal …
Read articleA 2026 meta-analysis of 4 randomized trials found that GLP-1 receptor agonists reduced obstructive sleep apnea severity by 13.89 apnea-hypopnea events per hour compared with placebo, alongsi…
Read articleCocaine relapse circuitry looks different when alcohol is part of the history. In a rat model, inhibiting prelimbic cortex neurons projecting to the nucleus accumbens core blocked cue-trigge…
Read articleA 2026 preprint following 964 adults who used a Chicago mobile medical unit for opioid use disorder care found 5 follow-up patterns over 12 months: 56% made 1 visit, while the remaining pati…
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