A 2026 automated MRI analysis of 153 adults with first cortical middle cerebral artery stroke found that remote deep gray nuclei changes were already measurable within 21 days, and 2 asymmetry markers independently predicted 3-month disability change: putamen volume Z-score asymmetry (β = −0.24; p = 0.021) and thalamic apparent diffusion coefficient asymmetry (β = …
A 2026 rat and astrocyte study found that human umbilical cord mesenchymal stem cell exosomes given 6 hours after experimental intracerebral hemorrhage reduced pro-inflammatory signaling and improved neurological recovery scores through the PI3K/AKT/PKM2/H3K18la pathway.1 The result is a mechanistic preclinical signal, not an emergency treatment for human brain hemorrhage. Research Highlights Exosomes were timed early: …
A 2026 medRxiv preprint involving 44 people with chronic post-stroke aphasia found reduced performance on nonverbal false-belief tasks in 23% of participants on the Reality-Unknown task and 36% on the Reality-Known task, with accuracy tied more clearly to cerebral microbleed burden than to aphasia severity.1 The result reframes social-cognitive testing after stroke as a vascular …
A 2026 secondary randomized-trial analysis found that low-intensity focused ultrasound and repetitive transcranial magnetic stimulation reached statistically similar 2-week post-treatment motor scores after subacute stroke, even though LIFU produced larger median Fugl–Meyer Assessment gains than rTMS: 7 vs. 2 upper-limb points and 3 vs. 1 lower-limb points.1 LIFU therefore carries the recovery-dynamics signal in this …