A 2026 FAERS pharmacovigilance study of 28,938 dystonia reports found the strongest reporting signal for metoclopramide, while antipsychotics dominated the high-volume psychiatric medication signal and most timed cases began within 30 days of drug exposure.1 Research Highlights 28,938 dystonia reports: Chen et al. analyzed 27,618 patients represented in FAERS reports from Q1 2004 through Q3 …
A 2026 medRxiv preprint involving 370 healthy adults found that each increase in neighborhood-deprivation percentile rank was associated with epigenetic age acceleration on 3 of 4 second-generation DNA-methylation clocks, with lifetime adversity explaining 20.3% of the GrimAge association and 23.3% of the PCGrimAge association.1 Research Highlights 3 of 4 clocks accelerated: each increase in Area …
A 2026 ABCD cohort preprint involving 10,112 youth found that childhood poverty strengthened the link between cumulative early-life adversity and later behavioral problems; among poverty-exposed youth, inhibitory-control fMRI profiles split children into higher-vulnerability and buffered pathways. Research Highlights Poverty steepened adversity risk: In 10,112 ABCD youth, childhood poverty amplified the baseline early-life-adversity-to-CBCL Total Problems slope …
A 2026 survey of 327 international students in Germany found high symptom burden: 46.5% screened positive for moderate-to-severe depression, 46.8% for moderate-to-severe anxiety, and 31.2% endorsed recent death or self-harm thoughts on PHQ-9 item 9. Only 10.9% of students with moderate-to-severe depression and/or anxiety reported professional help.1 Research Highlights 327 international students were surveyed: Karing …
A 2026 review of 52 studies found that chronic primary pain is linked to several physiological stress markers, especially cortisol, heart rate, heart-rate recovery, and mean arterial pressure. The pattern is real enough to study, but not clean enough to use as a simple biomarker panel for pain severity.1 Research Highlights 52 studies were reviewed: …
A 2026 scoping review screened 174 records and found 7 human studies linking sleep bruxism with gastroesophageal reflux disease.1 The signal was consistent but messy: case-control studies reported roughly 5- to 6-fold higher odds of bruxism with GERD, while instrumental studies suggested reflux episodes, arousals, swallowing, and jaw-muscle bursts may cluster during sleep. Research Highlights …
Trans people in Europe reported more discrimination and violence than cisgender lesbian, gay, and bisexual people in a 30-country survey of 138,212 respondents. The gap concentrated in identity-based discrimination, physical or sexual attacks, disability, ethnic-minority status, and gender identity within trans groups.1 Research Highlights 30-country gap was large and consistent: trans respondents reported discrimination in …