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Vitamin D for Prevention & Treatment of Parkinson’s Disease? (2023 Research)

Parkinson’s disease (PD), a prevalent neurodegenerative brain disease, is marked by the loss of dopaminergic neurons in the substantia nigra. Recent research has illuminated the significant role of Vitamin D (VD) in the brain, particularly its neuroprotective effects on these neurons. Highlights: Vitamin D’s Role in the Brain: Beyond its well-known functions in bone health, …

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Olibanum Gum Ineffective for Mild-to-Moderate Alzheimers Disease (2023 Study)

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline, significantly impacting the elderly. A recent clinical trial investigated the memory-improving potential of Olibanum, a traditional herbal remedy, in AD patients. Highlights: Alzheimer’s disease is a leading cause of dementia, characterized by memory loss and cognitive impairment. Olibanum, also known as Frankincense, has a …

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Alzheimer’s Disease, Microglia, & Environmental Risk Factors (2024 Evidence)

Alzheimer’s disease, a debilitating neurodegenerative condition, is influenced significantly by a blend of genetic, environmental, and lifestyle factors. New research focuses on environmental risk factors and microglia (the brain’s immune cells) for Alzheimer’s development. Highlights: Alzheimer’s Disease and Microglia: Alzheimer’s is characterized by cognitive decline, and microglia play a crucial role in its pathogenesis, acting …

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Marijuana Abuse & Early-Onset Frontotemporal Dementia: 34-Year-Old Male (Case Report)

A 34-year-old man developed symptoms of frontotemporal dementia (FTD), a rare form of early-onset dementia, after using cannabis for two years. This case highlights the potential risks of long-term cannabis use on brain health, especially for vulnerable individuals. Key Facts: The 34-year-old man used cannabis for two years before experiencing personality changes and behavioral symptoms …

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Gene Editing (CRISPR) for Alzheimers Disease Treatment

Alzheimer’s disease (AD) is an incurable neurodegenerative disease and the most common form of dementia. Research is ongoing to better understand AD pathogenesis and explore potential treatments. Genome editing tools like CRISPR/Cas9 offer new approaches to study and potentially treat AD. Key Facts: AD pathogenesis likely involves multiple genetic and environmental factors Gene mutations linked …

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Parkinsons Disease Diagnosis Years in Advance? Retinal Thinning via Optical Coherence Tomography (OCT)

Recent research provides evidence that Parkinson’s disease (PD) is associated with thinning of specific retinal layers that can be detected years before diagnosis. Key facts: Individuals with Parkinson’s disease (PD) had thinner retinal ganglion cell and inner plexiform layers compared to controls. Thinning of the inner nuclear layer, which contains dopamine cells, was also seen …

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Sinemet (Carbidopa-Levodopa) Side Effects & Adverse Reactions (List)

Sinemet is a pharmaceutical drug engineered by Merck that combines Carbidopa (a peripheral enzymatic inhibitor of DOPA decarboxylase) and Levodopa (an agent that crosses the blood-brain barrier to increase central concentrations of dopamine); hence it is frequently referred to as “Carbidopa-Levodopa.”  The drug was initially approved by the U.S. FDA in 1988 for the treatment …

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