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Hypoglossal Nerve Stimulation Improved Sleep Symptoms More Than Cognition

MHD featured image for hypoglossal nerve stimulation, sleep apnea symptoms, and cognition.

A 2026 CARDIOSA-12 secondary analysis found that active hypoglossal nerve stimulation improved sleepiness, insomnia, snoring, and sleep-related function, but objective cognitive test performance mostly did not improve compared with partially therapeutic stimulation.1 Symptom relief and measurable cognitive recovery answer separate clinical questions in treated obstructive sleep apnea. Research Highlights Subjective outcomes improved: active HGNS improved …

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Medical Cannabis for Chronic Pain: Stress and Sleep Drove Satisfaction

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A 2026 mixed-methods study of 32 chronic non-cancer pain patients found the strongest satisfaction signal when prescribed cannabis-based medicines affected stress, sleep, coping, anxiety, appetite, and daily function — not pain intensity alone.1 Research Highlights 32 patients were interviewed: Pombeiro Stein et al. studied adults from a German pain clinic who had used physician-prescribed cannabis-based …

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PHQ-15 and SSD-12 1-Week Versions Support Clinical Symptom Tracking

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A 2026 psychometric study of 354 Swedish participants found that 1-week versions of the PHQ-15 and SSD-12 mostly preserved internal consistency and construct validity, but reliability was acceptable mainly in clinical participants or when researchers averaged 2 timepoints. Research Highlights Clinical tracking looked more defensible than healthy screening: Hybelius et al. studied 194 people with …

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