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Catatonic Depression: Symptoms, Causes, & Treatment Options

Catatonic depression is defined as a state of stupor that results from neurogenic motor immobility and is thought to be caused by dysregulation of the neurotransmitters: GABA, glutamate and dopamine in the brain. It was first recognized in 1874 by Karl Ludwig Kahlbaum. In the current DSM (Diagnostic and Statistical Manual of Mental Disorders), “catatonia” …

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Suboxone (Buprenorphine) For Treatment-Resistant Depression: Partial Mu-Opioid Agonist

Suboxone (Buprenorphine) is a medication that is used by people withdrawing from narcotics (opioids). It helps alleviate withdrawal symptoms and most people end up able to experience a smooth withdrawal while on this particular drug. In people that have either extreme or treatment-resistant depression, many have turned to trying a variety of drugs besides that …

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MDMA (Ecstasy, Molly) Drug Withdrawal Symptoms: What You May Experience

MDMA (“Molly” or “Ecstasy”) withdrawal symptoms have not been extensively documented. Although most people use ecstasy on a recreational basis (e.g. once in awhile), there are some people that are more consistent with their usage. People who use Ecstasy often may actually become both psychologically and physically dependent upon this substance for everyday functioning. The …

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Lanicemine (AZD6765) For Treatment-Resistant Depression: NMDA Antagonist

Lanicemine (AZD6765) is an NMDA antagonist developed by the company AstraZeneca in hopes to help people with treatment-resistant depression. Let’s face it, if you have treatment-resistant depression, you are probably waiting for some sort of breakthrough in technology and/or a new class of drugs for treatment. Although many people find benefit from SSRI’s, TCA’s, and …

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Lithium For Treatment-Resistant Depression: An Effective Augmentation Strategy

Lithium carbonate has become a very popular augmentation option for treatment-resistant depression. ┬áIf you have treatment resistant depression, chances are that most psychiatrists have explored antidepressant monotherapy – or treatment with a single antidepressant. Once you have gone through the ringer of SSRI’s, TCA’s, and MAOI’s and found that none of the medications help your …

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Using Psilocybin (Magic Mushrooms) To Treat Depression

Would you have ever thought that the hallucinogenic drug Psilocybin, commonly referred to as “magic mushrooms” could help cure you of depression? Probably not. Although I have never tried them to treat my depression, there seems to be mounting scientific evidence in support of Psilocybin as a treatment option for cases of treatment-resistant depression. These …

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