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Epilepsy and Alzheimer’s Blood Biomarkers in Older Adults

MHD featured image for epilepsy, Alzheimer’s blood biomarkers, and AT(N) profiles in older adults.

A preprint in 84 older adults with epilepsy found that abnormal Alzheimer's-related blood biomarkers were common, but the biomarker categories did not line up neatly with cognitive impairment. Research Highlights Only 32.1% had normal biomarkers: 27 of 84 older adults with epilepsy were A−T−N− using blood-based amyloid, tau, and neurodegeneration markers.1 AD-continuum profiles were common: …

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Residual Sleepiness in Treated Sleep Apnea Linked to Memory Deficits

Stylized sleep-apnea treatment scene with CPAP, daytime sleepiness testing, and memory-task circuitry, representing cognitive deficits linked to residual sleepiness despite PAP adherence.

Some sleep apnea patients stay sleepy even when their CPAP is used 6+ hours a night and apnea events have been driven back to normal range. A 2026 cross-sectional study of 65 PAP-adherent adults found those residually sleepy patients performed measurably worse on global cognition, memory, executive function, attention, and processing speed than their well-rested …

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Antidepressants & Dementia Risk in Elderly Users: SSRIs vs. TCAs (2024 Study)

Recent research has uncovered connections between the use of antidepressants and the risk of developing dementia in the elderly. This complex relationship, marked by varying results and considerations, is becoming a critical area of study in geriatric medicine and mental health. In light of these findings, it is crucial to delve into the nuances of …

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