hit counter

cognitive enhancement

Latest Treatments for Frontotemporal Dementia (FTD): High-Dose Oxytocin Emerges as the Standout (2023 Review)

by

Frontotemporal dementia (FTD) is a challenging and impactful neurodegenerative disease. Recent research offers new insights into its management, particularly regarding the effectiveness of pharmacological treatments. Highlights: High-Dose Oxytocin Shows Promise: High-dose oxytocin (72 international units) has been linked to significant improvements in neuropsychiatric symptoms and daily interactive activities in FTD patients. Piracetam Poses Risks: Contrarily, …

Read more

CE-123 vs. R-Modafinil for Cognition: Dopamine Modulators (2023 Study)

by

Recent advancements in neuropharmacology have brought to light S-CE-123, a dopamine transporter inhibitor showing remarkable promise in cognitive enhancement. Its emergence alongside R-modafinil, a well-studied compound with a similar target, paves the way for a fascinating comparative study. This duo of compounds, entwined in the complex dance of brain chemistry, offers a glimpse into the …

Read more

Cognitive Enhancement Effects of Caffeine, Methylphenidate, Modafinil (Study)

by

In the pursuit of peak mental performance, scientific studies have explored the effects of stimulants like methylphenidate, modafinil, and caffeine on cognitive functions such as memory and attention. Recent research utilizing advanced neuroimaging techniques has begun to unravel the intricate ways these substances modulate brain activity and connectivity, offering insights into their potential as cognitive …

Read more

Hydrafinil (Fluorenol): A Modafinil Analogue with Questionable Safety

by

Hydrafinil (Fluorenol) is an unregulated research chemical originally synthesized by Cephalon Pharmaceuticals (now owned by Teva) as a eugeroic (wakefulness-promoting agent).  After its synthesis, fluorenol was one of several agents to be considered as a hypothetical successor to the popularized and FDA-approved drug, Provigil (Modafinil).  Comparative data from animal trials indicated that fluorenol exhibited ~39% …

Read more

TMS For Cognitive Enhancement (Transcranial Magnetic Stimulation)

by

TMS (Transcranial Magnetic Stimulation) is a technique utilized to stimulate specific regions of the brain via electromagnetic induction.  The regions that receive stimulation typically depend on an individual’s reason for using TMS.  For example, individuals using TMS for the treatment of depression may administer electrical pulses to the left prefrontal cortex, while individuals using TMS …

Read more

Genetically Modified Mice: PDE4B Inhibition Increases Intelligence, Reduces Anxiety

by

Perhaps you’ve heard of the fictional story “Flowers for Algernon” about a laboratory mouse named Algernon.  The mouse undergoes a nootropic-esque surgical procedure that dramatically amplifies his intelligence.  The experiment is deemed so successful, that scientists decide to test the procedure in a human character named Charlie Gordon. Prior to the artificial enhancement of Charlie’s …

Read more