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Statins and Dementia Risk: No Long-Term Signal in 322,358 Patients

Statins do not look like a dementia-prevention drug, but they do not look like a dementia hazard either. In 322,358 Kaiser Permanente Northern California patients followed for an average of 11.8 years, dementia diagnoses rose right after statins were started, then flattened: after the first year, the hazard ratio for Alzheimer’s disease and related dementias …

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Cannabis After Pregnancy Did Not Increase Hypertension Risk in nuMoM2b

Photoreal illustration of a postpartum woman with stethoscope and cannabis imagery, conveying cardiovascular implications of postpartum cannabis use.

A 2026 nuMoM2b Heart Health Study analysis tested whether urine-confirmed cannabis exposure 2–7 years after a first pregnancy predicted incident stage II hypertension; it did not: adjusted odds ratio (AOR) 1.05, 95% CI 0.63–1.76, with 216 of 4,079 participants developing hypertension.1 Research Highlights The headline result was null: cannabis exposure at the 2–7 year postpartum …

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Schizophrenia Dementia Risk: Diabetes, Head Injury, Substance Use

Photoreal illustration of an aging brain with cardiovascular and lifestyle risk imagery, conveying preventable dementia drivers in schizophrenia.

Patients with schizophrenia have substantially elevated dementia risk compared to the general population — roughly 2-3 times the age-adjusted rate — but the specific drivers within the schizophrenia population have been less well characterized. A 2026 case-control study by Ho et al. used population-based data to identify which factors specifically elevate dementia risk among schizophrenia …

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