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Doxycycline Causes Depression, Anxiety, Suicidal Ideation?

Doxycycline is a broad-spectrum tetracycline antibiotic that kills bacteria and protozoa by inhibiting protein synthesis (aminoacyl-tRNA to the mRNA-ribosome complex).  The drug was patented in 1957, introduced as a pharmaceutical in 1967, and has received medical approval as a treatment for conditions such as: acne, bacterial pneumonia, chlamydia, cholera, Lyme disease, Rocky Mountain spotted fever, …

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Cannabidiol (CBD) Side Effects & Adverse Reactions

CBD (Cannabidiol) is a phytocannabinoid with medicinal properties derived from the cannabis plant (i.e. marijuana).  Of all ~113 active phytocannabinoids, or plant-based chemical constituents within the cannabis plant, cannabidiol is most abundant and accounts for approximately 40% of the plant’s extract.  Unlike other phytocannabinoids that induce intoxicating effects (e.g. THC or tetrahydrocannabinol), cannabidiol is devoid …

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ZzzQuil Side Effects & Adverse Reactions (List)

ZzzQuil is an over-the-counter medication utilized most frequently to enhance sleep quality among individuals with allergies or the “common cold.”  However, because ZzzQuil is a potent sleep aid, individuals without health problems sometimes use the medication to help manage insomnia.  On occasion, ZzzQuil is even administered for the treatment of motion sickness and extrapyramidal symptoms …

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Rexulti Side Effects & Adverse Reactions (List)

Rexulti (Brexpiprazole), is an atypical antipsychotic approved by the FDA for the treatment of schizophrenia and major depressive disorder (as an adjunct).  The drug was engineered via collaboration between pharmaceutical companies Otsuka and Lundbeck and is considered the successor to Abilify (aripiprazole), a formerly top-selling antipsychotic medication with an expired patent.  Although Rexulti is marketed …

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Vyvanse Side Effects & Adverse Reactions (List)

Vyvanse (Lisdexamfetamine) is a prodrug comprised of the amino acid L-lysine coupled with dextroamphetamine, hence its chemical name “lis-dexamfetamine.”  As a prodrug, Vyvanse is inactive until ingested and enzymatically metabolized into l-lysine (an amino acid) and dextroamphetamine (a psychostimulant), the latter of which has been deemed effective for the treatment of ADHD and binge eating …

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Kratom Side Effects & Adverse Reactions (List)

Kratom (Mitragyna speciosa) is an evergreen tree of the coffee (Rubiaceae) family native to countries such as: Indonesia, Malaysia, Myanmar, Papua New Guinea, and Thailand.  It is best known for generating leaves that contain upwards of 40 distinct psychoactive compounds.  Pharmacological research indicates that the psychoactive constituents of kratom – most prominent being [indole alkaloids] …

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Ubiquinol Side Effects & Adverse Reactions (List)

Ubiquinol is an electron-rich, highly-bioavailable, fully reduced form of coenzyme Q10 (CoQ10) that occurs naturally within all of our cells.  When we’re young, the body is well-equipped to synthesize ubiquinone into ubiquinol (via Q Cycle reactions) which elicits an antioxidant effect to reduce free radicals and enhances cellular energy.  However, biological aging interferes with a …

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