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Negative Emotionality Reduces Frontal Midline Theta in 106 Recruits

Photoreal illustration of frontal-midline brain activity overlaid on a stylized portrait, conveying personality-brain link in cognitive control.

A 2026 EEG study of 106 Army National Guard recruits found that higher negative emotionality predicted poorer Go/No-Go discrimination (β = −.234, 95% CI −.392 to −.076) and lower frontal midline theta (β = −.149, 95% CI −.290 to −.001). The key result was not a vague personality-brain link: frontal midline theta, not occipital alpha, …

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Posttraumatic Growth in Farsi Refugees: 61% Explained by 4 Factors

Photoreal illustration of refugees in community setting with imagery of resilience and growth, conveying integrated trauma adaptation.

A 2026 survey of 230 Farsi-speaking refugees in German camps found a hard double signal: 69.1% screened above the RHS-15 threshold for depression, anxiety, and PTSD symptoms, while 4 protective factors explained 61% of posttraumatic-growth variance.1 Research Highlights High distress and growth coexisted: 159 of 230 participants (69.1%) scored ≥12 on the RHS-15 symptom scale, …

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Chronic Pain Plus Depression Alters Brain Structure

Photoreal illustration of brain regions affected by overlapping pain and depression networks, conveying comorbid neural signature.

A 2026 UK Biobank MRI preprint involving 71,214 adults found that chronic pain plus current depression had a structural brain profile that was more than chronic pain plus depression pasted together. The 1,377-person comorbid group showed widespread lower cortical volume, lower bilateral thalamic and hippocampal volume, lower left accumbens volume, and broad white-matter microstructure differences …

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Antidepressant Use in Pakistan (2026): SSRI Prescribing Patterns and Patient-Reported Side Effects

Photoreal illustration of a pharmacist counseling patient on antidepressant medication, conveying global pharmacovigilance.

Most antidepressant pharmacovigilance data come from high-income countries, leaving prescribing patterns and adverse-effect profiles in low- and middle-income countries underdocumented. A 2026 cross-sectional study by Riaz and colleagues describes antidepressant use in Pakistan, with patient-reported adverse effects mapped against prescription patterns.1 Research Highlights Antidepressant use in low- and middle-income countries (LMICs) has grown substantially but …

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Sensation Seeking Predicts Disordered Eating in Teens

Photoreal illustration of a teenager with overlapping symbols of food and personality traits, conveying sensation-seeking eating-disorder risk.

Sensation seeking has long been linked to risky behaviors in teens, but its role in eating-disorder psychopathology has been mixed. A 2026 study by Bogner and colleagues clarifies the picture in 400 German adolescents: sensation seeking matters for disordered eating, but the effects are moderated by weight status and emotional symptoms.1 Research Highlights Sensation seeking …

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How Betrayal Biases Trust: Selective Attention, Distrust, and Social Judgment

Betrayal does not just make people less trusting. It can also change what they pay attention to afterward. After a negative social surprise, people may start scanning more closely for signs of threat, which can make distrust easier to confirm and harder to undo. Research Highlights Selective observation: Son and Yoo 2026 modeled social inference …

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Antipsychotic Shortages Caused Drug Switching: 95,968-Patient Claims Study (2026)

First-generation antipsychotic (FGA) shortages are not just pharmacy annoyances; they force medication changes in people who may have taken years to stabilize on a tolerable regimen. Research Highlights 95,968 patients: Tabah 2026 used Komodo claims data to study people with psychotic-spectrum diagnoses taking shortage-affected first-generation antipsychotics. Switching was not evenly distributed: molindone reached 100% switching, …

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