Mental Health Daily

Mycobacterium vaccae Vaccine: A Novel Soil Bacteria-Based Treatment for Anxiety & Stress Disorders

by GLOOM

Stress can induce anxiety and depression, which appears to be mediated in part by stress-induced neuroinflammatory processes. The immunoregulatory bacterium Mycobacterium vaccae (M. vaccae) has anti-inflammatory and stress-resilient effects, but its impact on the brain is unclear. A study discovered that M. vaccae immunization: induces anti-inflammatory and immunoregulatory processes in the hippocampus, blocks stress-induced neuroinflammation …

Semaglutide & Empagliflozin May Treat Obesity-Related Cognitive Impairment (Mouse Study)

by GLOOM

Obesity now affects over 650 million adults globally and is a major risk factor for various chronic diseases including cognitive decline and impairment. Recent evidence shows a link between obesity, reduced brain volume and neuronal loss, increased dementia risk, and impaired learning, memory and cognition. Preliminary evidence suggests that weight loss drugs like semaglutide may …

Moon Rock Weed (Marijuana): Psychosis & Seizures in 20-Year-Old Male (Case Report)

by GLOOM

Cannabis use is associated with neurological and psychiatric side effects, but the risks of highly potent forms like “moon rocks” are not fully characterized. This case report describes psychosis and new-onset seizures in a 20-year-old following the first-time use of this THC-concentrated preparation. Key Facts: Moon rock cannabis contains high levels of THC, which acts …

Allopregnanolone Agonists for Depression: Brexanolone & Zuranolone in Focus (2023)

by GLOOM

Allopregnanolone agonists represent a promising new class of medications for treating depressive disorders. Evidence suggests that allopregnanolone agonists exhibit rapid-onset of antidepressant action – particularly in women with postpartum depression (PPD). Key facts: Allopregnanolone is a neurosteroid that acts as a positive allosteric modulator of GABAA receptors and is decreased in depressive disorders. The allopregnanolone …

Owners of Vicious Dog Breeds (Pit Bulls) Linked to Criminal Behaviors & Antisocial Personality Traits

by GLOOM

According to the Centers for Disease Control and Prevention (CDC), around 4.5 million dog bites occur annually, sending nearly 800,000 Americans to the emergency room. (R) An analysis of the characteristics of vicious dog owners and their pets suggests the public and lawmakers should reconsider breed-specific legislation. Key Facts: Owners of dogs classified as “vicious” …

Top 12 Antidepressant Nutrients & Foods for Depression Treatment

by GLOOM

Depression is a growing public health concern, but nutrition may offer a pathway for prevention and treatment. A new research study identified the most nutrient-dense foods for brain health to inform dietary recommendations. Key Facts: 12 nutrients have evidence supporting a role in preventing and treating depression, including omega-3s, B vitamins, minerals like magnesium, and …

Eye Tracking Technology for Rapid Depression Diagnosis in Young Adults

by GLOOM

Researchers have proposed a novel eye tracking method to rapidly screen for depression risk in young adults. This intelligent approach analyzes emotional perception deficits through objective eye movement biomarkers. Initial findings suggest promise for large-scale, low-cost depression screening without specialized doctors. Key Facts: The “eye movement emotional perception evaluation paradigm” extracts digital biomarkers related to …