Mental Health Daily

Vortioxetine Efficacy for Major Depression & Comorbid Anxiety (2023 Study)

by GLOOM

The RELIEVE study provides pivotal insights into the effectiveness of vortioxetine in treating patients with Major Depressive Disorder (MDD) co-morbid with Generalized Anxiety Disorder (GAD). A subgroup analysis of the observational study highlights significant improvements in patient functioning, depression severity, cognitive symptoms, and quality of life. The findings underscore vortioxetine’s potential as a beneficial treatment …

Prader-Willi Syndrome: New Treatments & Medications in Development & Clinical Trials (2023)

by GLOOM

Prader-Willi Syndrome (PWS) is a rare genetic condition marked by a diverse range of physical, mental, and behavioral challenges. Characterized by uncontrolled appetite and obesity, cognitive impairments, and social and behavioral issues, PWS presents unique challenges for patients and caregivers. Highlights: Prevalence and Genetics: PWS affects approximately 1 in 20,000 live births, caused by errors …

Psychiatric Disorders Linked to Accelerated Aging in UK Biobank Study (2023)

by GLOOM

Recent research utilizing data from the UK Biobank has shed light on the intricate relationship between biological aging and mental health, particularly focusing on depression and anxiety in older adults. A large-scale study linked advanced biological aging with increased risks of developing mental health issues, suggesting that biological aging could be a significant factor in …

Genetics of Anxiety Disorders: Insights from Human & Animal Research (2023)

by GLOOM

Anxiety disorders, characterized by excessive or prolonged fear and anxiety, are influenced by both genetic and environmental factors. Recent advancements in genetics and animal model research are shedding light on the intricate neurobiological mechanisms underlying these conditions. Highlights: Anxiety disorders have a moderate heritability, indicating a significant genetic component. Chronic psychosocial stress and traumatic events …

Stellate Ganglion Block (SGB) for Anxiety Disorders: Preliminary Evidence (2023)

by GLOOM

Stellate Ganglion Block (SGB), a medical procedure originally designed for pain management, is emerging as a potential treatment for anxiety disorders. This approach leverages its ability to modulate the sympathetic nervous system, which plays a significant role in anxiety symptoms. Highlights: SGB Procedure & Technicality: SGB involves injecting a local anesthetic near the stellate ganglion …

Optimizing Nicotine Replacement Therapy (NRT) to Quit Smoking (2023 Evidence)

by GLOOM

Nicotine Replacement Therapy (NRT) is a critical tool in the fight against smoking addiction, offering a beacon of hope for millions looking to quit. Recent studies have delved deep into the nuances of NRT, providing invaluable insights into its effectiveness, safety, and application. Highlights: Combination NRT has been found to be more effective than single-form …

Quetiapine Dosing for Depression Optimized with XGBoost Algorithm (2024 Study)

by GLOOM

Depression is a globally pervasive mental illness that often requires complex treatment strategies. One such strategy involves the use of Quetiapine, an antipsychotic medication, as an augmentation to antidepressants. However, determining the optimal dose of Quetiapine is challenging due to individual variability. A recent study utilizes machine learning techniques to develop a predictive model for …