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tDCS for the Treatment of Cravings in Drug Addiction (2023 Review)

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Transcranial direct current stimulation (tDCS) emerges as a promising, noninvasive treatment for reducing cravings in substance addiction. This technique involves the use of scalp electrodes to modulate neural activity, influencing cravings associated with drug addiction or substance dependence. Despite its promise, further research is needed to standardize protocols and understand long-term efficacy. Highlights: tDCS significantly …

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SSRI-Induced Sexual Dysfunction Reversed with “Drug Holidays” on Weekends (2024 Study)

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Selective serotonin reuptake inhibitors (SSRIs) are a mainstay in the treatment of various mental disorders but often come with the unwelcome side effect of sexual dysfunction. This issue can significantly affect patients’ adherence to their medication regime, often leading to treatment discontinuation. A recent clinical trial offers a new perspective, suggesting that ‘drug holidays’ – …

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Cannabis (Marijuana) Use & Psychosis: Does It Increase Risk? (2023 Evidence Review)

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The relationship between cannabis (marijuana) use and psychosis has been a topic of considerable scientific interest and public health concern. With changing legal statuses and societal attitudes towards cannabis use in many countries, understanding this relationship is more critical than ever. Highlights: Systematic reviews and meta-analyses show a consistent association between cannabis use and increased …

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Reset Modafinil Tolerance with Drug Holidays & Pitolisant-Bridging? (2023 Study)

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Narcolepsy, a chronic neurological disorder, significantly impacts the daily lives of those affected due to excessive daytime sleepiness (EDS). Modafinil has been a cornerstone in managing EDS, but its effectiveness can wane over time due to tolerance. An innovative approach, using the drug pitolisant during modafinil ‘drug holidays’, offers new hope for resetting tolerance and …

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4 Depression Subtypes Identified via PHQ-9 Tool: Affective, Somatic, Internalizing, Sensorimotor (2023 Study)

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Depression, a multifaceted mental health disorder affecting millions worldwide, has long been a challenge for both diagnosis and treatment. The standard method for evaluating depression in outpatient settings, the Patient Health Questionnaire-9 (PHQ-9), has traditionally been viewed as a unidimensional tool. However, recent research suggests that the complexities of Major Depressive Disorder (MDD) may be …

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Anabolic Androgenic Steroids vs. Sleep Quality & Psychological Distress in Weightlifters (2024 Study)

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Recent research has analyzed the relationship between the use of Anabolic Androgenic Steroids (AAS), sleep quality, and psychological distress. A new study specifically evaluated the effects of anabolic steroids on sleep patterns during both active use and withdrawal phases, among male weightlifters in Norway. Highlights: A large proportion of men using AAS report experiencing sleep …

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Optimal Dose of Exercise for Generalized Anxiety Disorder (GAD) in Aging Adults (2024 Study)

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Generalized Anxiety Disorder (GAD), a prevalent condition among older adults, may be significantly influenced by physical activity levels. Recent research from The Irish Longitudinal Study on Ageing (TILDA) provides groundbreaking insights into how even minimal physical activity can reduce the risk of GAD. Highlights: Minimal Dose for Maximum Benefit: Even low levels of moderate-to-vigorous physical …

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