Mental Health Daily

Chronic Stress Alters the Gut Microbiome & Intestinal Barrier in Mice with Sex-Specific Effects (2023 Study)

by GLOOM

The gut-brain axis, a complex communication network linking the gastrointestinal tract and the brain, plays a pivotal role in maintaining both mental and physical health. Recent studies illuminate how chronic stress disrupts this intricate system, particularly affecting the intestinal barrier in the jejunum, and contributes to the pathogenesis of Major Depressive Disorder (MDD). This emerging …

Symptom Provocation in Psychiatric Disorders: TMS, EEG, Neural Circuits for Personalized Treatment (2023 Review)

by GLOOM

Symptom provocation, a cornerstone of psychiatric research and therapy, offers a fascinating glimpse into the intricate relationship between brain activity and psychiatric symptoms. By deliberately triggering symptoms, researchers and clinicians can identify neurophysiological biomarkers and target them with personalized therapies, such as transcranial magnetic stimulation (TMS). This technique not only enhances our understanding of psychiatric …

Effects of DMT on Mental Health: Depression & Anxiety in Healthy Adults (2024 Study)

by GLOOM

In the quest for innovative treatments for psychiatric disorders, the study of psychedelics has taken a significant leap forward. Among these, Dimethyltryptamine (DMT), known for its rapid onset and short duration of action, emerges as a compelling alternative to traditional therapies. Recent studies have begun to explore its potential, particularly in treating depression and anxiety, …

Dietary Sugar Intake & Depression: 100g/day Increase Equals 28% Higher Risk (NHANES Data: 2011-2018)

by GLOOM

In recent years, the intricate relationship between dietary habits and mental health has come under scientific scrutiny, revealing insights that challenge our daily consumption choices. Specifically, the consumption of dietary sugar has been identified as a potential factor influencing the prevalence of depression among adults in the United States. A study utilizing data from the …

Abnormal EEG Microstates Linked to Major Depression & Related Cognitive Impairment (2024 Study)

by GLOOM

In the quest to understand the enigmatic nature of depression, scientists are turning to the intricate patterns of brain activity, seeking clues hidden within the electrical storm of thoughts and emotions. By examining electroencephalography (EEG) microstates—brief, recurring patterns of brain activity—researchers have begun to piece together how depression alters the fundamental dynamics of the brain. …

Antidepressants & Iron Pathways: Targeting Ferroptosis to Treat Depression (2023 Review)

by GLOOM

Depression, a debilitating mental disorder, stands as a significant challenge to global health, potentially becoming the leading cause of disability worldwide. Recent research has unearthed a promising connection between ferroptosis, a newly discovered form of cell death, and the onset of depression, offering fresh avenues for developing innovative antidepressant therapies. Traditional Chinese Medicine (TCM) and …

tDCS of the DLPFC Treats Anhedonia in Depression & Improves Social Functioning (2024 Study)

by GLOOM

In the quest to find more effective treatments for depression, particularly the challenging symptom of anhedonia, Transcranial Direct Current Stimulation (tDCS) emerges as a promising option. This non-invasive brain stimulation technique targets specific brain regions to modulate activity and potentially alleviate symptoms. A recent study has shed light on the efficacy and safety of targeting …