hit counter

Hydroxyzine For Dogs: Potential Uses In Canines

Hydroxyzine is a drug that was initially approved by the FDA in the 1950s as an antihistamine.  Most users know hydroxyzine under the brands Vistaril and Atarax, each of which are still popularly prescribed to treat medical conditions such as: allergic skin reactions, generalized anxiety disorders, and nausea resulting from motion sickness.  In some cases, …

Read more

Hydroxyzine (Vistaril, Atarax) For Anxiety Disorders

Hydroxyzine (brand names Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class.  It was initially synthesized in 1956 and thereafter marketed in the U.S. by the pharmaceutical juggernaut, Pfizer.  Although a relatively ancient medication by today’s standards, hydroxyzine is still commonly prescribed: as a preoperative anesthetic, analgesic, and anxiolytic adjunct; as an …

Read more

Inositol Side Effects & Adverse Reactions (List)

Inositol is a non-essential nutrient and natural sugar present within phospholipids of cell membranes, plasma lipoproteins, and the nuclei.  Chemically, there are 9 subtypes of inositol each with distinctive stereoisomers, the most common of which is known as “myo-inositol.”  Within the human body, myo-inositol is synthesized from glucose and accounts for 95% of total free …

Read more

Adderall Tolerance: Causes & How To Prevent It

Nearly all individuals taking Adderall can attest to the fact that its psychostimulatory effect is most potent after an initial “first-time” dosage.  Thereafter, its efficacy is generally maintained for weeks, or perhaps months after the initial dosage with favorable results.  However, eventually Adderall users may notice that its therapeutic psychostimulation seems to have dwindled and/or …

Read more

Long Term Effects of Modafinil: Hypothetical Risks & Rewards

Modafinil (brand name “Provigil”) is a blockbuster eugeroic drug synthesized by Cephalon Pharmaceuticals (now Teva) and approved in 1998 for the treatment of excessive daytime sleepiness (EDS) associated with narcolepsy.  It was since approved for the treatment of excessive daytime sleepiness associated with obstructive sleep apnea, as well as to normalize circadian rhythms in diagnoses …

Read more

Hydrafinil (Fluorenol): A Modafinil Analogue with Questionable Safety

Hydrafinil (Fluorenol) is an unregulated research chemical originally synthesized by Cephalon Pharmaceuticals (now owned by Teva) as a eugeroic (wakefulness-promoting agent).  After its synthesis, fluorenol was one of several agents to be considered as a hypothetical successor to the popularized and FDA-approved drug, Provigil (Modafinil).  Comparative data from animal trials indicated that fluorenol exhibited ~39% …

Read more