tau pathology

Published research on tau pathology.

Neurodegenerative DiseasesJun 6, 2026

NDST3 Suppression Restores Lysosome Acidity in Alzheimer’s Mouse Models

A 2026 mechanistic Alzheimer’s study found that suppressing NDST3 shifted lysosomal pH in APP695Swe neuronal cells from 5.6 back below 5.0, then reduced amyloid-β, MAPT/tau pathology, neuron…

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BrainMay 18, 2026

Total-Body Tau PET Links Brain-Organ Coupling to Alzheimer’s Cognition

A 2026 total-body tau-PET study of 28 people with Alzheimer’s disease and 23 biomarker-negative controls found stronger brain-organ network connectivity in Alzheimer’s disease than in biomar…

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