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SSRI-Induced Sexual Dysfunction Reversed with “Drug Holidays” on Weekends (2024 Study)

Selective serotonin reuptake inhibitors (SSRIs) are a mainstay in the treatment of various mental disorders but often come with the unwelcome side effect of sexual dysfunction. This issue can significantly affect patients’ adherence to their medication regime, often leading to treatment discontinuation. A recent clinical trial offers a new perspective, suggesting that ‘drug holidays’ – …

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Antidepressants & Dementia Risk in Elderly Users: SSRIs vs. TCAs (2024 Study)

Recent research has uncovered connections between the use of antidepressants and the risk of developing dementia in the elderly. This complex relationship, marked by varying results and considerations, is becoming a critical area of study in geriatric medicine and mental health. In light of these findings, it is crucial to delve into the nuances of …

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Evening Chronotype & Lower Efficacy of SSRI Antidepressants (2024 Study)

Recent research in the Australian Genetics of Depression Study reveals a fascinating connection between an individual’s chronotype and the efficacy of antidepressants. A study, focusing on selective-serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), suggests that evening chronotypes may experience poorer responses to these medications. Highlights: Chronotype Impact: Individuals with an evening chronotype reported …

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Analyzing Cardiovascular Effects & Risks of Newer Antidepressants

Depression is a prevalent and serious condition in older adults and those with cardiovascular disease. Serotonin reuptake inhibitors (SSRIs) are commonly used to treat depression, but when they’re ineffective, alternative antidepressants must be considered. Key Facts: Depression in Older Adults and Cardiovascular Patients: Affects 15-20% of patients with coronary heart disease. Limitations of SSRIs: While …

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Long-Term Antidepressant (SSRI) Use Increasing: Overprescription & Withdrawal Hesitancy

The rise in antidepressant prescribing, especially selective serotonin reuptake inhibitors (SSRIs) since the 1980s, is a complex phenomenon with broad implications for public health. While these medications are crucial for many, the increase in long-term use has raised concerns about overprescription, side effects, and withdrawal challenges. Key Facts: Rising Prescriptions: Antidepressant prescriptions, particularly SSRIs, have …

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Antidepressants (SSRIs) & Permanent Sexual Dysfunction (PSSD): A Risk to Consider

Treatment with commonly prescribed antidepressants may cause a small proportion of patients to develop persistent sexual side effects that continue even after stopping the medication. This condition is known as post-SSRI sexual dysfunction (PSSD). Key Facts: The study found 0.46% of patients developed erectile dysfunction that continued after stopping antidepressants. This suggests the risk of …

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Social Anxiety Disorder Caused By Too Much Serotonin?

Those with social anxiety disorder are reported to suffer from debilitating, uncontrollable anxiety in social situations.  This condition, also known as “social phobia” can lead to an intense fear of public speaking, forming friendships, maintaining social bonds, and even getting a job.  Individuals living with social anxiety often isolate themselves, suffer from low self-esteem, and …

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