The most-quoted figure on veteran suicide is “22 a day,” produced from 21-state death-certificate data for 1999–2010.2 The VA’s 2024 Annual Report — with mortality data through 2022 — puts the current daily count at 17.6 Veteran suicides, but the per-Veteran rate has gone the other way.1 Research Highlights Daily count was 17.6: 6,407 Veteran …
Psychiatric brain biomarkers have produced a large research literature but little routine clinical use. A 2026 evidence map found 441 primary studies and 27 systematic reviews of neuroimaging or neurophysiologic biomarkers for mental-health disorders, yet the field still looks too small, cross-sectional, and depression-heavy for ordinary diagnostic or treatment decisions.1 Research Highlights Large map, weak …
A 2026 pilot randomized trial involving 36 older U.S. veterans with PTSD symptoms found that a structured social-function group therapy produced stronger signals for romantic and family functioning than a support group, with condition-by-time effects of eta-squared = 0.072 and eta-squared = 0.112. The same trial did not show a specific advantage for friendships and …
A 2026 fMRI study of 1,006 healthy young adults found that emotional pictures were remembered better than neutral pictures, but the brain signal split after arousal was modeled: amygdala and insula effects dropped out, while negative and positive valence kept separate cortical encoding patterns.1 Research Highlights Emotional pictures had the recall advantage: in the full …
A 2026 retrospective case series of 22 adults with treatment-resistant depression and comorbid PTSD found that trauma re-experiencing during intranasal esketamine disappeared over later sessions in 72.7% of patients, while 27.3% stopped esketamine because the flashbacks persisted.1 Research Highlights Flashbacks usually faded, but not always: In 16 of 22 patients (72.7%), esketamine-related trauma re-experiencing disappeared …
A 2026 case report linked 1 mg nightly guanfacine modified-release to first-ever cessation of intrusive deliberate self-harm thoughts in a 16-year-old with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD) traits, borderline personality disorder (BPD) traits, and post-traumatic stress disorder (PTSD). The same case became more interesting after the patient stopped taking guanfacine and the self-harm …
A 2026 Nature mouse study found that basolateral amygdala astrocyte Ca2+ signals tracked fear retrieval and extinction, then showed causality: 3 mg/kg CNO manipulations of astrocyte DREADDs pushed early-extinction freezing in opposite directions while both disrupting later extinction retrieval.1 Research Highlights Astrocytes tracked fear state: after 3 tone-shock pairings and 2 days of 25 cue-only …