MentalHealthDaily

Deep Brain Stimulation (DBS) of Nucleus Accumbens (NAc) for Treatment-Resistant Depression (4 Case Reports)

by GLOOM

Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD) explores the cutting-edge intersection of technology and neuroscience, offering hope to those for whom traditional treatments have failed. By targeting specific brain areas, such as the nucleus accumbens, DBS attempts to modulate the underlying neural circuits associated with depression. A recent review analyzed case reports documenting significant …

Targeting the Nucleus Accumbens D1-MSN cAMP for Depression & Crocin’s Rapid Antidepressant Effect (2024 Study)

by GLOOM

Depression, a debilitating mental health disorder, has long puzzled scientists and clinicians alike. Recent research sheds light on the nucleus accumbens (NAc), a brain region associated with reward and pleasure, highlighting its critical role in the pathophysiology of depression. Specifically, the study shows how manipulating cyclic adenosine monophosphate (cAMP) levels within dopamine D1 receptor medium …

Fatty Acid Sensor GPR120 (FFAR4) Treatment Target for Anxiety & Neuroinflammation (2023 Study)

by GLOOM

In the quest to understand the intricate relationship between our diet, brain, and behavior, scientists are turning their focus to a unique receptor, GPR120. This protein, known for interacting with long-chain fatty acids like omega-3s, is shedding new light on how our body’s inflammation and metabolism can directly affect our mental health. By exploring GPR120’s …

Gene Therapy For Depression: A Futuristic Treatment

by GLOOM

Despite the fact that pharmaceutical companies continue to promote the concept of “chemical imbalances” as the root cause of depression, this is a vast oversimplification of an infinitely more complex condition. While a chemical imbalance may be one of the primary contributing factors to a person’s depression, what causes the chemicals (neurotransmitters) to become imbalanced …