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Calorie Restriction (CR) Effects on Brain Gene Expression & Behavior in Rats (2023 Study)

Calorie restriction (CR) is increasingly recognized for its potential benefits beyond just weight loss, including reducing anxiety, slowing aging, and mitigating the risk of obesity. Recent research focused on how both short-term and long-term CR affect behavior and gene expression in various brain regions, providing insights into the molecular underpinnings of these effects. Highlights: Behavioral …

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Antidepressants & Dementia Risk in Elderly Users: SSRIs vs. TCAs (2024 Study)

Recent research has uncovered connections between the use of antidepressants and the risk of developing dementia in the elderly. This complex relationship, marked by varying results and considerations, is becoming a critical area of study in geriatric medicine and mental health. In light of these findings, it is crucial to delve into the nuances of …

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Microplastics & Nanoplastics Cross Blood-Brain Barrier within Hours & May Cause Damage

Microplastics and nanoplastics (MNPs) from the breakdown of plastic materials pollute the environment and make their way into the human body, raising concerns over potential health impacts. Research shows that microplastics and nanoplastics are able to cross the blood-brain barrier in mice within 2 hours of ingestion. Key Facts: Polystyrene nanoparticles with a size of …

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Parkinsons Disease Diagnosis Years in Advance? Retinal Thinning via Optical Coherence Tomography (OCT)

Recent research provides evidence that Parkinson’s disease (PD) is associated with thinning of specific retinal layers that can be detected years before diagnosis. Key facts: Individuals with Parkinson’s disease (PD) had thinner retinal ganglion cell and inner plexiform layers compared to controls. Thinning of the inner nuclear layer, which contains dopamine cells, was also seen …

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Dementia Linked To Benzodiazepines, Sleeping Pills, Anticholinergics

In recent years, increasing evidence has suggested that certain types of commonly prescribed medications may cause increased risk of developing dementia. This ranges from drugs used to treat anxiety (e.g. Xanax) to over-the-counter drugs (e.g. Benadryl). A majority of these medications tend to depress activity in the CNS and help minimize arousal and/or anxiety. Dementia …

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